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The map label for this gene is fixC [H]

Identifier: 154244098

GI number: 154244098

Start: 133567

End: 134874

Strand: Reverse

Name: fixC [H]

Synonym: Xaut_0140

Alternate gene names: 154244098

Gene position: 134874-133567 (Counterclockwise)

Preceding gene: 154244099

Following gene: 154244097

Centisome position: 2.54

GC content: 62.23

Gene sequence:

>1308_bases
ATGATCGACGAAAAATTCGATGCCATCGTCGTTGGCGCCGGCATGGCCGGCAATGCGGCGGCCTACACCCTGGCCAAGCG
CGGCCTCAAGGTGCTTCAGCTGGAGCGCGGCGAGTATTCCGGCTCCAAGAACGTCCAGGGCGCCATCCTCTACGCTGACA
TGATGGAAAAGATCATTCCCGATTTCCGGGAAGACGCCCCGCTGGAGCGCCATCTGATCGAGCAGCGCTTCTGGATGATG
ACGGACAATTCGCACACCGGCCTGCAGTACCGGTCCGACGAATTCAACGAGGAAAGCCCGAACCGCTACACCATCATCCG
GGCGCAGTTCGACAAGTGGTTCTCCAGCAAGGTGCGCGAGGCCGGTGCCCTCGTGGTCTGCGAGACCACGGTGACCGAGC
TGGTCCAGGACGCCTACGGCAAGGTGATCGGCGTGAAGACCGATCGCGGCGGCGGCCAGATCCATGCGGACGTGGTGGTG
CTGGCGGAAGGCGTCACCGGCCTGCTCGGCACCCGCGCCGGCTTGCGCAAGATTCCCAAGCCCACCGAGGTCGCCCTCGC
GGTCAAGGAAATGCACTTCCTGCCGCAGGAGGTGATCGAGCAGCGCTTCAACCTCAAGGGCAATGAAGGCGTCGTGATCG
AGGCCGTCGGCACCATCTCCAAGGGGATGACCGGCATGGGCTTCATCTACTCGAACCGGGAGTGCATCTCGATCGGGCTC
GGCTGCCTGGTGTCGGACTTCCAGGCGAGCGGCGTCTCGCCCTACCAACTGCTCGAGAAGTTCAAGAGCCACCCCTCCGT
CGCACCGCTGCTGGAAGGCTCCGAGGTGAAGGAATATGCCGCCCACCTCATTCCCGAGGGCGGCTACAAGGCGATCCCCC
AGCTCTATGGCGACGGCTGGGTGGTGGTGGGCGACGCGGCCCAGCTCAACAACGCCATCCATCGCGAGGGCTCCAACCTC
GCCATGACCTCGGGGCGCATCGCTGCGGAGACGATCTTCCAGATCAAGTCCCGCAAGGACCCCATGACTGCCCAGAATCT
GTCGCTCTACAAGAAGATGCTGGACGACAGCTTCATTATGAAGGATCTTAAGAAGTACAAGGATATGCCGAAGCTTCTGC
ATATCCAGTCGCAGAACTTCTTCCTCACCTATCCCCAGCTGGTCAACAAGGCCATGGAGAACTATCTGCGTGTCGATGGC
ACGCCGAAGAAGGAGAAGCAGAAGCTGACTTTGAAGTCCTTCGTTTCCGCGCGGTCGTGGGCGGGCCTGTTCGGCGACGC
CTTCCGCCTCGCGCGCGCCTGGCGCTGA

Upstream 100 bases:

>100_bases
GACCGACGCGGTGCGCTTCCTGCCCATGCTGACGGAAGCTTTCTCCAAGCGCCTGTCCGCACATTCCCGCGACAAGCTCG
CCAGCTGAAGGATAGCTCCG

Downstream 100 bases:

>100_bases
CGTCCTTTTCGGTCAGCCGAACCTTAGCTCGGACCAAGCGTCCGACATCAGATTGCTCGAACCCAGGCGGCGGATGTGAT
CCGCCGCCGCCAACCTTCGG

Product: electron-transferring-flavoprotein dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MIDEKFDAIVVGAGMAGNAAAYTLAKRGLKVLQLERGEYSGSKNVQGAILYADMMEKIIPDFREDAPLERHLIEQRFWMM
TDNSHTGLQYRSDEFNEESPNRYTIIRAQFDKWFSSKVREAGALVVCETTVTELVQDAYGKVIGVKTDRGGGQIHADVVV
LAEGVTGLLGTRAGLRKIPKPTEVALAVKEMHFLPQEVIEQRFNLKGNEGVVIEAVGTISKGMTGMGFIYSNRECISIGL
GCLVSDFQASGVSPYQLLEKFKSHPSVAPLLEGSEVKEYAAHLIPEGGYKAIPQLYGDGWVVVGDAAQLNNAIHREGSNL
AMTSGRIAAETIFQIKSRKDPMTAQNLSLYKKMLDDSFIMKDLKKYKDMPKLLHIQSQNFFLTYPQLVNKAMENYLRVDG
TPKKEKQKLTLKSFVSARSWAGLFGDAFRLARAWR

Sequences:

>Translated_435_residues
MIDEKFDAIVVGAGMAGNAAAYTLAKRGLKVLQLERGEYSGSKNVQGAILYADMMEKIIPDFREDAPLERHLIEQRFWMM
TDNSHTGLQYRSDEFNEESPNRYTIIRAQFDKWFSSKVREAGALVVCETTVTELVQDAYGKVIGVKTDRGGGQIHADVVV
LAEGVTGLLGTRAGLRKIPKPTEVALAVKEMHFLPQEVIEQRFNLKGNEGVVIEAVGTISKGMTGMGFIYSNRECISIGL
GCLVSDFQASGVSPYQLLEKFKSHPSVAPLLEGSEVKEYAAHLIPEGGYKAIPQLYGDGWVVVGDAAQLNNAIHREGSNL
AMTSGRIAAETIFQIKSRKDPMTAQNLSLYKKMLDDSFIMKDLKKYKDMPKLLHIQSQNFFLTYPQLVNKAMENYLRVDG
TPKKEKQKLTLKSFVSARSWAGLFGDAFRLARAWR
>Mature_435_residues
MIDEKFDAIVVGAGMAGNAAAYTLAKRGLKVLQLERGEYSGSKNVQGAILYADMMEKIIPDFREDAPLERHLIEQRFWMM
TDNSHTGLQYRSDEFNEESPNRYTIIRAQFDKWFSSKVREAGALVVCETTVTELVQDAYGKVIGVKTDRGGGQIHADVVV
LAEGVTGLLGTRAGLRKIPKPTEVALAVKEMHFLPQEVIEQRFNLKGNEGVVIEAVGTISKGMTGMGFIYSNRECISIGL
GCLVSDFQASGVSPYQLLEKFKSHPSVAPLLEGSEVKEYAAHLIPEGGYKAIPQLYGDGWVVVGDAAQLNNAIHREGSNL
AMTSGRIAAETIFQIKSRKDPMTAQNLSLYKKMLDDSFIMKDLKKYKDMPKLLHIQSQNFFLTYPQLVNKAMENYLRVDG
TPKKEKQKLTLKSFVSARSWAGLFGDAFRLARAWR

Specific function: Could be required for the formation of a functional nitrogenase Fe protein. Probably accepts electrons from fixA/fixB and reduces a quinone [H]

COG id: COG0644

COG function: function code C; Dehydrogenases (flavoproteins)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF-QO/fixC family [H]

Homologues:

Organism=Homo sapiens, GI119703746, Length=402, Percent_Identity=26.6169154228856, Blast_Score=120, Evalue=3e-27,
Organism=Escherichia coli, GI1786227, Length=414, Percent_Identity=38.1642512077295, Blast_Score=280, Evalue=9e-77,
Organism=Escherichia coli, GI1787991, Length=413, Percent_Identity=37.772397094431, Blast_Score=280, Evalue=1e-76,
Organism=Escherichia coli, GI87082155, Length=418, Percent_Identity=33.4928229665072, Blast_Score=223, Evalue=2e-59,
Organism=Caenorhabditis elegans, GI25144720, Length=394, Percent_Identity=24.8730964467005, Blast_Score=118, Evalue=5e-27,
Organism=Saccharomyces cerevisiae, GI6324932, Length=361, Percent_Identity=29.3628808864266, Blast_Score=105, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24652256, Length=401, Percent_Identity=25.4364089775561, Blast_Score=115, Evalue=5e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.5.5.-

Molecular weight: Translated: 48375; Mature: 48375

Theoretical pI: Translated: 8.88; Mature: 8.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDEKFDAIVVGAGMAGNAAAYTLAKRGLKVLQLERGEYSGSKNVQGAILYADMMEKIIP
CCCCCCCEEEEECCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCCEEEEHHHHHHHHCC
DFREDAPLERHLIEQRFWMMTDNSHTGLQYRSDEFNEESPNRYTIIRAQFDKWFSSKVRE
CHHCCCCHHHHHHHHHHEEEECCCCCCCEECCCCCCCCCCCEEEEEEEHHHHHHHHHHHH
AGALVVCETTVTELVQDAYGKVIGVKTDRGGGQIHADVVVLAEGVTGLLGTRAGLRKIPK
CCCEEEEHHHHHHHHHHHCCCEEEEEECCCCCEEEEEEEEEECCHHHHHHCCHHHHHCCC
PTEVALAVKEMHFLPQEVIEQRFNLKGNEGVVIEAVGTISKGMTGMGFIYSNRECISIGL
CHHHHHHHHHHHCCHHHHHHHHHCCCCCCCEEEEEECHHHCCCCCCEEEECCCHHHHHHH
GCLVSDFQASGVSPYQLLEKFKSHPSVAPLLEGSEVKEYAAHLIPEGGYKAIPQLYGDGW
HHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHCCCE
VVVGDAAQLNNAIHREGSNLAMTSGRIAAETIFQIKSRKDPMTAQNLSLYKKMLDDSFIM
EEECCHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
KDLKKYKDMPKLLHIQSQNFFLTYPQLVNKAMENYLRVDGTPKKEKQKLTLKSFVSARSW
HHHHHHHCCCHHEEEECCCEEEECHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHH
AGLFGDAFRLARAWR
HHHHHHHHHHHHHCC
>Mature Secondary Structure
MIDEKFDAIVVGAGMAGNAAAYTLAKRGLKVLQLERGEYSGSKNVQGAILYADMMEKIIP
CCCCCCCEEEEECCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCCEEEEHHHHHHHHCC
DFREDAPLERHLIEQRFWMMTDNSHTGLQYRSDEFNEESPNRYTIIRAQFDKWFSSKVRE
CHHCCCCHHHHHHHHHHEEEECCCCCCCEECCCCCCCCCCCEEEEEEEHHHHHHHHHHHH
AGALVVCETTVTELVQDAYGKVIGVKTDRGGGQIHADVVVLAEGVTGLLGTRAGLRKIPK
CCCEEEEHHHHHHHHHHHCCCEEEEEECCCCCEEEEEEEEEECCHHHHHHCCHHHHHCCC
PTEVALAVKEMHFLPQEVIEQRFNLKGNEGVVIEAVGTISKGMTGMGFIYSNRECISIGL
CHHHHHHHHHHHCCHHHHHHHHHCCCCCCCEEEEEECHHHCCCCCCEEEECCCHHHHHHH
GCLVSDFQASGVSPYQLLEKFKSHPSVAPLLEGSEVKEYAAHLIPEGGYKAIPQLYGDGW
HHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHCCCE
VVVGDAAQLNNAIHREGSNLAMTSGRIAAETIFQIKSRKDPMTAQNLSLYKKMLDDSFIM
EEECCHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
KDLKKYKDMPKLLHIQSQNFFLTYPQLVNKAMENYLRVDGTPKKEKQKLTLKSFVSARSW
HHHHHHHCCCHHEEEECCCEEEECHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHH
AGLFGDAFRLARAWR
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1850088 [H]