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The map label for this gene is gstB [H]

Identifier: 154244087

GI number: 154244087

Start: 126431

End: 127090

Strand: Reverse

Name: gstB [H]

Synonym: Xaut_0129

Alternate gene names: 154244087

Gene position: 127090-126431 (Counterclockwise)

Preceding gene: 154244091

Following gene: 154244086

Centisome position: 2.39

GC content: 66.67

Gene sequence:

>660_bases
ATGGCCGCGATGAAGTTCTACATGACGCCCGGCTCCTGCTCCACCGGCATCCACATCATCCTGGAAGAGCTGGAAGAGGT
GTTCGAGGCTCACATCGTGAACCTCCCGGCGGGCGACCACTTCAAGCCGGACTATGTTGCGGTGAACCCCAAGTCCACCA
TCCCGGCCCTGGTGCGGCCGGACGGCAGCGCGCTGACCGAAGTGGTCTCCATCGCCTATTGGCTGGCCCGCAGCCGGGGG
CGCGGCCGGCTGTGGCCAGCCGACGTGGATGCGGAGGCCCGCGCCCTCGAAGCCATGGTCTATGTGGTGGGCACGGTGCA
TGGCCAGGGCTTCGCGCGCATCTTTTCCACCCCGACCTTCGCCGCCAGCCCCGCCGACCGGCCCAAGGTGGAAACGCTCG
GCCGCGATATCGTCAGCCAGGGCTTTTCCATCCTCGATGCCGCGCTCGCGGGCCGCGACTATGTGGCGGGCAGCTTTTCG
GCGGCCGATCCCATCCTGTTCTACGTGGAATTCTGGGCGGACAAGACCGGCATGGAGTTGCCGGCCAATCTCGCCGCCCA
CTACCGGCGCATGCTGGAGCGGCCGGTGGTGCAGCGCGTGCTGCGTGAGGAAGGCTACAATCTCGCCCTCCTGGGCGTGA
AGCAAAGCCTTCCGAACTGA

Upstream 100 bases:

>100_bases
GGCCGGTGCCCGAACTGCCCCGATATTTGCATGAAGCATGCCGATTGCCGCCTGCCCGGCCGGGACGGCGCACGACGACG
CGCGCGAGGGAAGACGCCTG

Downstream 100 bases:

>100_bases
CACGATTTGCCAAGCGACAGCCAAGAAGGAGAGTGCCCATGGCCGACATGTTCGTGGTGACTGAAGAGAACCGGGACGAC
ATGTCCCGCAAGGCAGGCAT

Product: glutathione S-transferase domain-containing protein

Products: NA

Alternate protein names: GST B1-1 [H]

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MAAMKFYMTPGSCSTGIHIILEELEEVFEAHIVNLPAGDHFKPDYVAVNPKSTIPALVRPDGSALTEVVSIAYWLARSRG
RGRLWPADVDAEARALEAMVYVVGTVHGQGFARIFSTPTFAASPADRPKVETLGRDIVSQGFSILDAALAGRDYVAGSFS
AADPILFYVEFWADKTGMELPANLAAHYRRMLERPVVQRVLREEGYNLALLGVKQSLPN

Sequences:

>Translated_219_residues
MAAMKFYMTPGSCSTGIHIILEELEEVFEAHIVNLPAGDHFKPDYVAVNPKSTIPALVRPDGSALTEVVSIAYWLARSRG
RGRLWPADVDAEARALEAMVYVVGTVHGQGFARIFSTPTFAASPADRPKVETLGRDIVSQGFSILDAALAGRDYVAGSFS
AADPILFYVEFWADKTGMELPANLAAHYRRMLERPVVQRVLREEGYNLALLGVKQSLPN
>Mature_218_residues
AAMKFYMTPGSCSTGIHIILEELEEVFEAHIVNLPAGDHFKPDYVAVNPKSTIPALVRPDGSALTEVVSIAYWLARSRGR
GRLWPADVDAEARALEAMVYVVGTVHGQGFARIFSTPTFAASPADRPKVETLGRDIVSQGFSILDAALAGRDYVAGSFSA
ADPILFYVEFWADKTGMELPANLAAHYRRMLERPVVQRVLREEGYNLALLGVKQSLPN

Specific function: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles [H]

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1787923, Length=212, Percent_Identity=34.9056603773585, Blast_Score=77, Evalue=8e-16,
Organism=Drosophila melanogaster, GI85725204, Length=161, Percent_Identity=32.2981366459627, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI17737923, Length=161, Percent_Identity=32.2981366459627, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: =2.5.1.18 [H]

Molecular weight: Translated: 23952; Mature: 23820

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAMKFYMTPGSCSTGIHIILEELEEVFEAHIVNLPAGDHFKPDYVAVNPKSTIPALVRP
CCCEEEEECCCCCCCHHHHHHHHHHHHHHHHEEECCCCCCCCCCEEEECCCCCCCEEECC
DGSALTEVVSIAYWLARSRGRGRLWPADVDAEARALEAMVYVVGTVHGQGFARIFSTPTF
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHCCCCC
AASPADRPKVETLGRDIVSQGFSILDAALAGRDYVAGSFSAADPILFYVEFWADKTGMEL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCCC
PANLAAHYRRMLERPVVQRVLREEGYNLALLGVKQSLPN
CHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCC
>Mature Secondary Structure 
AAMKFYMTPGSCSTGIHIILEELEEVFEAHIVNLPAGDHFKPDYVAVNPKSTIPALVRP
CCEEEEECCCCCCCHHHHHHHHHHHHHHHHEEECCCCCCCCCCEEEECCCCCCCEEECC
DGSALTEVVSIAYWLARSRGRGRLWPADVDAEARALEAMVYVVGTVHGQGFARIFSTPTF
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHCCCCC
AASPADRPKVETLGRDIVSQGFSILDAALAGRDYVAGSFSAADPILFYVEFWADKTGMEL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCCC
PANLAAHYRRMLERPVVQRVLREEGYNLALLGVKQSLPN
CHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8761466; 8436105; 2661269; 8645008; 9655824 [H]