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The map label for this gene is yciR [C]

Identifier: 154244039

GI number: 154244039

Start: 86322

End: 87755

Strand: Direct

Name: yciR [C]

Synonym: Xaut_0081

Alternate gene names: 154244039

Gene position: 86322-87755 (Clockwise)

Preceding gene: 154244038

Following gene: 154244040

Centisome position: 1.63

GC content: 67.99

Gene sequence:

>1434_bases
ATGCGCATGATCGCGATCCACGCTCAAACTGAACGAAAGCGGCTGGACAGATCTGTCCGCTGCGCTGAAAAACGCCGCCC
CTGGGCAAGGAAACAGCGGCTTCGCGGTCTGATCCGTCCAGATCCAGCAGTCTGCGCGACCGCAGGTGCCGCTTGCGGCA
GAAAATCCTTGTCTAGCGCTCGGATACAGGCGCTCTTCACCTCAAACGACACGCCACTTGGGGAATGCAGGCTGAAGGAC
GTCAACGACACCCTCGGCCACGATGCCGGCGACGCGGCGCTGATGGAGACCGCCCACCGGCTGGATGCCCTGCTGGAGCC
GGACGGCCTGCTGGCCCGGCTCGGCGGGGACGAGTTCGTGGCGGTGGTGAAGGGGGCGGCGCCGGTCGCCGCCGGCCAGC
GGCTGGCCCACGCCATTCTCGCCGAACTACGCCGGCCGGTGCTGCACGCCGGACGCCATTTCACCACCCGGGCCAGCATC
GGGCTCGCCGCCTGCCCGGACCACGATTGCTCCTATGGCGAACTGATGAAGGACGCCGACCTCGCCCTTTATGCCGCCAA
GCAGCAGGGCCGCAACCGCGCGGTGGTCTACGCCCCGGCCATGCGGCAGGCGGTGCTGGAGCGGGTGGCGCTCAACCGCG
CCATGCGGGCTGCGCTGGCGGAGGACGAGATCATTCCCTATTACCAGCCCAAGGTGTCGCTCGTGACTGGGCGCATCGAG
GGGCTGGAAGCTCTGGTGCGCTGGCGCCGCTCGCCGCACAGCGTGCTGTCGCCGGGATCGTTCGAGGCCGCGCTGACCGA
TCCGGAGCTGGCCGTCCTCATTGGTGAGCGCATGGTGCGGCGGGTGTCGACAGACGTGCGCGGCTGGATCGAGGCGGGCC
ATCCGTGCGGGCGAATCGCCATCAACCTGGCGCCTGCCCAGTTCGCGGGTGGCGACCTCGCGGCGACGCTGCTGCGCCAG
TTCCACGCCGCGGGGGTGGAGCCGACCCATTTCGACGTGGAGATCACCGAGACCGTCTTCCTCGGCCGCAGCTCCGACCA
CGTGGCGCCTATCCTTGATGAGCTCTACCGGGCGGGGGTGCGCATCGCGCTCGACGATTTCGGCACCGGCTACGCCGGCC
TCATCCACCTGAAGCAGCTGCCCATCGACACCATCAAGATCGACCAGAGCTTCGTGAAGGATATCGAGCGCGACGCCTTC
GACACCGCCATCGTCTGCGCCGTGATCGATCTTGGCCGCAACCTCGGCATGCGGGTGGTGGCCGAGGGGCTGGAAACCGC
CGGGCAGGCCCGCTTTCTCAAGGACAAGCGCTGCGAGCTGGCGCAGGGCTTCTTCTTCTTCCGTCCCCTCGACGGGGCGG
AGATGACCGAGCTGCTGCGCAAAGAGGGCGATGAGGCCGCCGCCGCCCGTCTCGCAACGTTTGAGACGAACTGA

Upstream 100 bases:

>100_bases
ACGCCCGCACCATCACCTTCCAGCTGGCCGAGGTCGCTGTCACCGGCACGATGGTACGCGCCATCCTCGCCGCTATCCGC
CGATTGCGAGCGCCACCGCT

Downstream 100 bases:

>100_bases
CTGCGATCGCGTCGGACATCGGACGGGTGATGCGACCCGGCGAAAGCATAACCCCCGGGATTGCTTTGGTGCGCTGCAGC
GCCGCAGGGTGAGGAAAGTT

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 477; Mature: 477

Protein sequence:

>477_residues
MRMIAIHAQTERKRLDRSVRCAEKRRPWARKQRLRGLIRPDPAVCATAGAACGRKSLSSARIQALFTSNDTPLGECRLKD
VNDTLGHDAGDAALMETAHRLDALLEPDGLLARLGGDEFVAVVKGAAPVAAGQRLAHAILAELRRPVLHAGRHFTTRASI
GLAACPDHDCSYGELMKDADLALYAAKQQGRNRAVVYAPAMRQAVLERVALNRAMRAALAEDEIIPYYQPKVSLVTGRIE
GLEALVRWRRSPHSVLSPGSFEAALTDPELAVLIGERMVRRVSTDVRGWIEAGHPCGRIAINLAPAQFAGGDLAATLLRQ
FHAAGVEPTHFDVEITETVFLGRSSDHVAPILDELYRAGVRIALDDFGTGYAGLIHLKQLPIDTIKIDQSFVKDIERDAF
DTAIVCAVIDLGRNLGMRVVAEGLETAGQARFLKDKRCELAQGFFFFRPLDGAEMTELLRKEGDEAAAARLATFETN

Sequences:

>Translated_477_residues
MRMIAIHAQTERKRLDRSVRCAEKRRPWARKQRLRGLIRPDPAVCATAGAACGRKSLSSARIQALFTSNDTPLGECRLKD
VNDTLGHDAGDAALMETAHRLDALLEPDGLLARLGGDEFVAVVKGAAPVAAGQRLAHAILAELRRPVLHAGRHFTTRASI
GLAACPDHDCSYGELMKDADLALYAAKQQGRNRAVVYAPAMRQAVLERVALNRAMRAALAEDEIIPYYQPKVSLVTGRIE
GLEALVRWRRSPHSVLSPGSFEAALTDPELAVLIGERMVRRVSTDVRGWIEAGHPCGRIAINLAPAQFAGGDLAATLLRQ
FHAAGVEPTHFDVEITETVFLGRSSDHVAPILDELYRAGVRIALDDFGTGYAGLIHLKQLPIDTIKIDQSFVKDIERDAF
DTAIVCAVIDLGRNLGMRVVAEGLETAGQARFLKDKRCELAQGFFFFRPLDGAEMTELLRKEGDEAAAARLATFETN
>Mature_477_residues
MRMIAIHAQTERKRLDRSVRCAEKRRPWARKQRLRGLIRPDPAVCATAGAACGRKSLSSARIQALFTSNDTPLGECRLKD
VNDTLGHDAGDAALMETAHRLDALLEPDGLLARLGGDEFVAVVKGAAPVAAGQRLAHAILAELRRPVLHAGRHFTTRASI
GLAACPDHDCSYGELMKDADLALYAAKQQGRNRAVVYAPAMRQAVLERVALNRAMRAALAEDEIIPYYQPKVSLVTGRIE
GLEALVRWRRSPHSVLSPGSFEAALTDPELAVLIGERMVRRVSTDVRGWIEAGHPCGRIAINLAPAQFAGGDLAATLLRQ
FHAAGVEPTHFDVEITETVFLGRSSDHVAPILDELYRAGVRIALDDFGTGYAGLIHLKQLPIDTIKIDQSFVKDIERDAF
DTAIVCAVIDLGRNLGMRVVAEGLETAGQARFLKDKRCELAQGFFFFRPLDGAEMTELLRKEGDEAAAARLATFETN

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=374, Percent_Identity=33.4224598930481, Blast_Score=216, Evalue=2e-57,
Organism=Escherichia coli, GI87081921, Length=383, Percent_Identity=29.7650130548303, Blast_Score=181, Evalue=6e-47,
Organism=Escherichia coli, GI226510982, Length=380, Percent_Identity=28.6842105263158, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI87081743, Length=241, Percent_Identity=34.0248962655602, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1790496, Length=234, Percent_Identity=31.1965811965812, Blast_Score=128, Evalue=7e-31,
Organism=Escherichia coli, GI87081845, Length=246, Percent_Identity=32.1138211382114, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1788502, Length=250, Percent_Identity=29.2, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1786507, Length=257, Percent_Identity=30.7392996108949, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1787055, Length=284, Percent_Identity=29.5774647887324, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI87082096, Length=247, Percent_Identity=30.7692307692308, Blast_Score=108, Evalue=8e-25,
Organism=Escherichia coli, GI87081980, Length=268, Percent_Identity=29.1044776119403, Blast_Score=105, Evalue=7e-24,
Organism=Escherichia coli, GI1788381, Length=349, Percent_Identity=25.7879656160458, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1788849, Length=283, Percent_Identity=26.1484098939929, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1786584, Length=123, Percent_Identity=38.2113821138211, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1787410, Length=226, Percent_Identity=27.8761061946903, Blast_Score=75, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 52044; Mature: 52044

Theoretical pI: Translated: 7.79; Mature: 7.79

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRMIAIHAQTERKRLDRSVRCAEKRRPWARKQRLRGLIRPDPAVCATAGAACGRKSLSSA
CCEEEEECHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHHCHHHHHHH
RIQALFTSNDTPLGECRLKDVNDTLGHDAGDAALMETAHRLDALLEPDGLLARLGGDEFV
HEEEEEECCCCCCCCEEEECCCHHHCCCCCHHHHHHHHHHHHHHCCCCCCEEECCCCEEE
AVVKGAAPVAAGQRLAHAILAELRRPVLHAGRHFTTRASIGLAACPDHDCSYGELMKDAD
EEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCEEECCCCCCCHHHHHHCCH
LALYAAKQQGRNRAVVYAPAMRQAVLERVALNRAMRAALAEDEIIPYYQPKVSLVTGRIE
HHEEEHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEHHHH
GLEALVRWRRSPHSVLSPGSFEAALTDPELAVLIGERMVRRVSTDVRGWIEAGHPCGRIA
HHHHHHHHCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
INLAPAQFAGGDLAATLLRQFHAAGVEPTHFDVEITETVFLGRSSDHVAPILDELYRAGV
EEECCCHHCCCHHHHHHHHHHHHCCCCCCEEEEEEEEEEEECCCCCCHHHHHHHHHHCCC
RIALDDFGTGYAGLIHLKQLPIDTIKIDQSFVKDIERDAFDTAIVCAVIDLGRNLGMRVV
EEEEECCCCCHHHHEEHHHCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
AEGLETAGQARFLKDKRCELAQGFFFFRPLDGAEMTELLRKEGDEAAAARLATFETN
HHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHCCCHHHHHHHHEECCC
>Mature Secondary Structure
MRMIAIHAQTERKRLDRSVRCAEKRRPWARKQRLRGLIRPDPAVCATAGAACGRKSLSSA
CCEEEEECHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHHCHHHHHHH
RIQALFTSNDTPLGECRLKDVNDTLGHDAGDAALMETAHRLDALLEPDGLLARLGGDEFV
HEEEEEECCCCCCCCEEEECCCHHHCCCCCHHHHHHHHHHHHHHCCCCCCEEECCCCEEE
AVVKGAAPVAAGQRLAHAILAELRRPVLHAGRHFTTRASIGLAACPDHDCSYGELMKDAD
EEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCEEECCCCCCCHHHHHHCCH
LALYAAKQQGRNRAVVYAPAMRQAVLERVALNRAMRAALAEDEIIPYYQPKVSLVTGRIE
HHEEEHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEHHHH
GLEALVRWRRSPHSVLSPGSFEAALTDPELAVLIGERMVRRVSTDVRGWIEAGHPCGRIA
HHHHHHHHCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
INLAPAQFAGGDLAATLLRQFHAAGVEPTHFDVEITETVFLGRSSDHVAPILDELYRAGV
EEECCCHHCCCHHHHHHHHHHHHCCCCCCEEEEEEEEEEEECCCCCCHHHHHHHHHHCCC
RIALDDFGTGYAGLIHLKQLPIDTIKIDQSFVKDIERDAFDTAIVCAVIDLGRNLGMRVV
EEEEECCCCCHHHHEEHHHCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
AEGLETAGQARFLKDKRCELAQGFFFFRPLDGAEMTELLRKEGDEAAAARLATFETN
HHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHCCCHHHHHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]