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The map label for this gene is clpB [H]

Identifier: 153952470

GI number: 153952470

Start: 1258693

End: 1261272

Strand: Direct

Name: clpB [H]

Synonym: JJD26997_1422

Alternate gene names: 153952470

Gene position: 1258693-1261272 (Clockwise)

Preceding gene: 153951100

Following gene: 153952147

Centisome position: 68.22

GC content: 32.25

Gene sequence:

>2580_bases
ATGGCAAATATACAAGATTTTTTAACTGATAATATGCTTTCAAACCTTGAAAGTGCAGCATCTTTAGCTATACATTCTAA
AAATACTGAAGTCGTACCTTTGCACCTTTTATGGGCTTTAAGCGTAGATAGTACAAGTATTTTAAATCAAATTTTAAATA
AATTAAATATTTCTAAAGAAGCCTTAGAACTTGAAATTAAAAGCAGAATTTCAAAACTTGCAACGAGTTCAAATGTAAGC
CGTGAAAATATACGCTTTTCCAATGAACTTATAAATTCATTAGAAAATGCTAAAGGATTAATGAGCGCTAATGGAGATAG
TTATTTAAGTGTGGATACTTGGCTTATAAGTGAAAGTCAAAAAAGTCCTATTAAAGAAATTTTGGCGCAATTTTTAGATT
TAAGAGAATTTCAAAAAGAGTTTGAAAGTCTAAGAGCAGGACGCAAAATTGATAGCAAAACAAGCGATGAAACCTTAGAT
AGCTTAAATAAATTTGGTATAGATTTAACCTTAAAAGCAAGTGAGGGTAAACTTGATCCTGTTATAGGTAGAGAAGAAGA
AATCGAACGTTTAATGCAAATTTTAATACGCAAAACCAAAAACAATCCTATACTTTTAGGTGAACCAGGTGTAGGAAAAA
CAGCTATAGTAGAAGCTCTAGCACAAAGAATTATCAAAAAAGATGTTCCAAAATCTTTACAAAATAAAAAAGTTATCGCT
CTTGATATGAGTGCTTTAATTGCAGGTGCAAAATACAGAGGAGAATTTGAAGATAGATTAAAAGCTGTGGTTAATGAAGT
GATAAAAAGTGAAAATATCATTCTTTTTATCGATGAAATTCACACTATAGTAGGGGCTGGAGCGAGTGAAGGTAGCATGG
ATGCGGCAAATATTTTAAAACCCGCTCTTGCAAGAGGTGAGCTCCATACCATAGGTGCAACTACTTTAAAAGAATATCGT
AAATATTTTGAAAAAGATGCGGCCTTGCAACGCCGTTTTCAACCTGTAAATGTAGGTGAACCAAGTGTTAATGAGGCTTT
AGCTATGTTAAGGGGTATAAAAGAAAAGCTTGAAATTCATCATAATGTAACTATAAATGATAGTGCTTTAGTAGCCGCAG
CTAAACTTTCAAAGCGTTATATAGCGGATCGTTTTTTACCTGATAAGGCTATTGATTTAATCGATGAAGCTGCAGCTGAA
CTGAAAATGCAAATTGAAAGTGAACCAAGTTCTTTAAGAAAGGTACGCAAAGACATAGAAACTTTAGAAGTTGAAAATGA
AGCCTTAAAAATGGAAAATGATGAGAAAAATCAAAAAAGACTCGATGAAATCGCAAAAGAACTAGCCAATTTAAAAGAAA
AACAAAATGCCTTAAATTCACAGTTTGAAAATGAAAAAAGCGTTTTTGATGGCATAAGTACCAAGAAAAAAGAAATTGAC
CTGCTTAAAAATGAAGCTTCTTTAGCTAAAACTAGGGGTGAATTTCAAAAAGCAGCCGAGCTAGAGTATGGAAAAATTCC
AAATCTTGAAAAAGAAGTAGAAATTTTAGAAGATAAATGGAAAAAAATGAGTGAAAATGGAGTTTTACTTAAAAATCAAG
TAGATGAGGATTTGGTTGCTGGAATTTTAAGCAAATGGACGGGTATTAGCGTACAAAAAATGCTAACTTCTGAAAAACAA
AAATTCTTAGAAGTGGAAAAACATTTAAAAGAAAGTGTCATAGGACAAGATAAAGCCTTAAGTGCTTTAGCTAGAGCCAT
TAAACGCAACAAAGCAGGACTTAATACGGATAATAAGCCTATAGGAAGCTTTTTATTTTTAGGACCAACAGGGGTAGGAA
AAACACAATCAGCTAAAGCTTTGGCAAAATTTTTATTTGACGATGAAAAAGCAATGATTCGCTTTGATATGAGTGAATTT
ATGGAAAAACATAGTGTTTCAAGACTCTTAGGTGCGCCTCCAGGATACATAGGACATGAAGAAGGTGGAGAGCTTACTGA
AGCTGTACGAAGAAAACCTTATAGCGTACTTTTGTTTGATGAAGTTGAAAAAGCGCATAAAGATGTATTTAATGTGCTTT
TAGGGATTTTAGATGATGGTAGAGCAACCGATAGCAAAGGCGTAACAGTGGATTTTAAAAATACCATTATCATTTTAACT
TCTAATATCGCCTCAAATGTTATCATGAATTTAAATGGAAAAGAACAAGAAGATGCGGTAAAAAATGAATTAAAAAATTT
CTTTAAACCTGAGTTTTTAAACCGCCTAGATGATATTATCACCTTTAATCCACTTGGAAAAGATGAAGCTTATGAAATAG
TCAAGCTTTTATTTAAAGATTTACAAATGAGCTTAGAAAACAAGGGGATAAAAGCAAGTTTAAGCGAAAATGCAGCCCTT
TTAATCGCTAAAGATGGTTTTGACCCTGATTTTGGTGCTAGACCTTTAAGAAGAGCTATTTATGATCTCATAGAAGATAA
ATTAAGCGATATGATACTTGCTGATGAACTTCATGAAAATGATAACATTTTAATCGATGCCGAAAATGATGAAATCGTGA
TCAAAAAAATACAAATTTGA

Upstream 100 bases:

>100_bases
TCATTTATCCCATTATTTAAAAAATTTTACTCAATTAACTTGACATTATATGACTAAAGTTATATAATAGCAAGCATATA
AACTAAATAAAGGATAAAAC

Downstream 100 bases:

>100_bases
AAGTAGAATTTTCTACTTTCTTGATTTTTTAAATTCCTTTCTTAATCTTCTTATCTTAAACCACAATTTGATATACCCCC
CCCATACCAATTCTTACTTG

Product: ATP-dependent chaperone protein ClpB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 859; Mature: 858

Protein sequence:

>859_residues
MANIQDFLTDNMLSNLESAASLAIHSKNTEVVPLHLLWALSVDSTSILNQILNKLNISKEALELEIKSRISKLATSSNVS
RENIRFSNELINSLENAKGLMSANGDSYLSVDTWLISESQKSPIKEILAQFLDLREFQKEFESLRAGRKIDSKTSDETLD
SLNKFGIDLTLKASEGKLDPVIGREEEIERLMQILIRKTKNNPILLGEPGVGKTAIVEALAQRIIKKDVPKSLQNKKVIA
LDMSALIAGAKYRGEFEDRLKAVVNEVIKSENIILFIDEIHTIVGAGASEGSMDAANILKPALARGELHTIGATTLKEYR
KYFEKDAALQRRFQPVNVGEPSVNEALAMLRGIKEKLEIHHNVTINDSALVAAAKLSKRYIADRFLPDKAIDLIDEAAAE
LKMQIESEPSSLRKVRKDIETLEVENEALKMENDEKNQKRLDEIAKELANLKEKQNALNSQFENEKSVFDGISTKKKEID
LLKNEASLAKTRGEFQKAAELEYGKIPNLEKEVEILEDKWKKMSENGVLLKNQVDEDLVAGILSKWTGISVQKMLTSEKQ
KFLEVEKHLKESVIGQDKALSALARAIKRNKAGLNTDNKPIGSFLFLGPTGVGKTQSAKALAKFLFDDEKAMIRFDMSEF
MEKHSVSRLLGAPPGYIGHEEGGELTEAVRRKPYSVLLFDEVEKAHKDVFNVLLGILDDGRATDSKGVTVDFKNTIIILT
SNIASNVIMNLNGKEQEDAVKNELKNFFKPEFLNRLDDIITFNPLGKDEAYEIVKLLFKDLQMSLENKGIKASLSENAAL
LIAKDGFDPDFGARPLRRAIYDLIEDKLSDMILADELHENDNILIDAENDEIVIKKIQI

Sequences:

>Translated_859_residues
MANIQDFLTDNMLSNLESAASLAIHSKNTEVVPLHLLWALSVDSTSILNQILNKLNISKEALELEIKSRISKLATSSNVS
RENIRFSNELINSLENAKGLMSANGDSYLSVDTWLISESQKSPIKEILAQFLDLREFQKEFESLRAGRKIDSKTSDETLD
SLNKFGIDLTLKASEGKLDPVIGREEEIERLMQILIRKTKNNPILLGEPGVGKTAIVEALAQRIIKKDVPKSLQNKKVIA
LDMSALIAGAKYRGEFEDRLKAVVNEVIKSENIILFIDEIHTIVGAGASEGSMDAANILKPALARGELHTIGATTLKEYR
KYFEKDAALQRRFQPVNVGEPSVNEALAMLRGIKEKLEIHHNVTINDSALVAAAKLSKRYIADRFLPDKAIDLIDEAAAE
LKMQIESEPSSLRKVRKDIETLEVENEALKMENDEKNQKRLDEIAKELANLKEKQNALNSQFENEKSVFDGISTKKKEID
LLKNEASLAKTRGEFQKAAELEYGKIPNLEKEVEILEDKWKKMSENGVLLKNQVDEDLVAGILSKWTGISVQKMLTSEKQ
KFLEVEKHLKESVIGQDKALSALARAIKRNKAGLNTDNKPIGSFLFLGPTGVGKTQSAKALAKFLFDDEKAMIRFDMSEF
MEKHSVSRLLGAPPGYIGHEEGGELTEAVRRKPYSVLLFDEVEKAHKDVFNVLLGILDDGRATDSKGVTVDFKNTIIILT
SNIASNVIMNLNGKEQEDAVKNELKNFFKPEFLNRLDDIITFNPLGKDEAYEIVKLLFKDLQMSLENKGIKASLSENAAL
LIAKDGFDPDFGARPLRRAIYDLIEDKLSDMILADELHENDNILIDAENDEIVIKKIQI
>Mature_858_residues
ANIQDFLTDNMLSNLESAASLAIHSKNTEVVPLHLLWALSVDSTSILNQILNKLNISKEALELEIKSRISKLATSSNVSR
ENIRFSNELINSLENAKGLMSANGDSYLSVDTWLISESQKSPIKEILAQFLDLREFQKEFESLRAGRKIDSKTSDETLDS
LNKFGIDLTLKASEGKLDPVIGREEEIERLMQILIRKTKNNPILLGEPGVGKTAIVEALAQRIIKKDVPKSLQNKKVIAL
DMSALIAGAKYRGEFEDRLKAVVNEVIKSENIILFIDEIHTIVGAGASEGSMDAANILKPALARGELHTIGATTLKEYRK
YFEKDAALQRRFQPVNVGEPSVNEALAMLRGIKEKLEIHHNVTINDSALVAAAKLSKRYIADRFLPDKAIDLIDEAAAEL
KMQIESEPSSLRKVRKDIETLEVENEALKMENDEKNQKRLDEIAKELANLKEKQNALNSQFENEKSVFDGISTKKKEIDL
LKNEASLAKTRGEFQKAAELEYGKIPNLEKEVEILEDKWKKMSENGVLLKNQVDEDLVAGILSKWTGISVQKMLTSEKQK
FLEVEKHLKESVIGQDKALSALARAIKRNKAGLNTDNKPIGSFLFLGPTGVGKTQSAKALAKFLFDDEKAMIRFDMSEFM
EKHSVSRLLGAPPGYIGHEEGGELTEAVRRKPYSVLLFDEVEKAHKDVFNVLLGILDDGRATDSKGVTVDFKNTIIILTS
NIASNVIMNLNGKEQEDAVKNELKNFFKPEFLNRLDDIITFNPLGKDEAYEIVKLLFKDLQMSLENKGIKASLSENAALL
IAKDGFDPDFGARPLRRAIYDLIEDKLSDMILADELHENDNILIDAENDEIVIKKIQI

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=329, Percent_Identity=34.6504559270517, Blast_Score=193, Evalue=7e-49,
Organism=Escherichia coli, GI1788943, Length=858, Percent_Identity=48.2517482517483, Blast_Score=812, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=265, Percent_Identity=48.3018867924528, Blast_Score=260, Evalue=2e-70,
Organism=Saccharomyces cerevisiae, GI6320464, Length=704, Percent_Identity=47.4431818181818, Blast_Score=651, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=860, Percent_Identity=40.1162790697674, Blast_Score=605, Evalue=1e-174,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 95989; Mature: 95858

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANIQDFLTDNMLSNLESAASLAIHSKNTEVVPLHLLWALSVDSTSILNQILNKLNISKE
CCCHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEEEEEEECCCHHHHHHHHHHHHCCCHH
ALELEIKSRISKLATSSNVSRENIRFSNELINSLENAKGLMSANGDSYLSVDTWLISESQ
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHCCCCCCEEEEEEEEECCCC
KSPIKEILAQFLDLREFQKEFESLRAGRKIDSKTSDETLDSLNKFGIDLTLKASEGKLDP
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCEEEEECCCCCCCC
VIGREEEIERLMQILIRKTKNNPILLGEPGVGKTAIVEALAQRIIKKDVPKSLQNKKVIA
CCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCHHHCCCEEEE
LDMSALIAGAKYRGEFEDRLKAVVNEVIKSENIILFIDEIHTIVGAGASEGSMDAANILK
EEHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCCCCHHHHHH
PALARGELHTIGATTLKEYRKYFEKDAALQRRFQPVNVGEPSVNEALAMLRGIKEKLEIH
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
HNVTINDSALVAAAKLSKRYIADRFLPDKAIDLIDEAAAELKMQIESEPSSLRKVRKDIE
CCEEECCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
TLEVENEALKMENDEKNQKRLDEIAKELANLKEKQNALNSQFENEKSVFDGISTKKKEID
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCHHHHH
LLKNEASLAKTRGEFQKAAELEYGKIPNLEKEVEILEDKWKKMSENGVLLKNQVDEDLVA
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHH
GILSKWTGISVQKMLTSEKQKFLEVEKHLKESVIGQDKALSALARAIKRNKAGLNTDNKP
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCC
IGSFLFLGPTGVGKTQSAKALAKFLFDDEKAMIRFDMSEFMEKHSVSRLLGAPPGYIGHE
CCCEEEECCCCCCCCHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCC
EGGELTEAVRRKPYSVLLFDEVEKAHKDVFNVLLGILDDGRATDSKGVTVDFKNTIIILT
CCCHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCEEEEEE
SNIASNVIMNLNGKEQEDAVKNELKNFFKPEFLNRLDDIITFNPLGKDEAYEIVKLLFKD
CCHHCCCEECCCCCCHHHHHHHHHHHHCCHHHHHHHHHHEECCCCCCHHHHHHHHHHHHH
LQMSLENKGIKASLSENAALLIAKDGFDPDFGARPLRRAIYDLIEDKLSDMILADELHEN
HHHHHHCCCCEEECCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
DNILIDAENDEIVIKKIQI
CCEEEECCCCCEEEEEECC
>Mature Secondary Structure 
ANIQDFLTDNMLSNLESAASLAIHSKNTEVVPLHLLWALSVDSTSILNQILNKLNISKE
CCHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEEEEEEECCCHHHHHHHHHHHHCCCHH
ALELEIKSRISKLATSSNVSRENIRFSNELINSLENAKGLMSANGDSYLSVDTWLISESQ
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHCCCCCCEEEEEEEEECCCC
KSPIKEILAQFLDLREFQKEFESLRAGRKIDSKTSDETLDSLNKFGIDLTLKASEGKLDP
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCEEEEECCCCCCCC
VIGREEEIERLMQILIRKTKNNPILLGEPGVGKTAIVEALAQRIIKKDVPKSLQNKKVIA
CCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCHHHCCCEEEE
LDMSALIAGAKYRGEFEDRLKAVVNEVIKSENIILFIDEIHTIVGAGASEGSMDAANILK
EEHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCCCCHHHHHH
PALARGELHTIGATTLKEYRKYFEKDAALQRRFQPVNVGEPSVNEALAMLRGIKEKLEIH
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
HNVTINDSALVAAAKLSKRYIADRFLPDKAIDLIDEAAAELKMQIESEPSSLRKVRKDIE
CCEEECCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
TLEVENEALKMENDEKNQKRLDEIAKELANLKEKQNALNSQFENEKSVFDGISTKKKEID
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCHHHHH
LLKNEASLAKTRGEFQKAAELEYGKIPNLEKEVEILEDKWKKMSENGVLLKNQVDEDLVA
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHH
GILSKWTGISVQKMLTSEKQKFLEVEKHLKESVIGQDKALSALARAIKRNKAGLNTDNKP
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCC
IGSFLFLGPTGVGKTQSAKALAKFLFDDEKAMIRFDMSEFMEKHSVSRLLGAPPGYIGHE
CCCEEEECCCCCCCCHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCC
EGGELTEAVRRKPYSVLLFDEVEKAHKDVFNVLLGILDDGRATDSKGVTVDFKNTIIILT
CCCHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCEEEEEE
SNIASNVIMNLNGKEQEDAVKNELKNFFKPEFLNRLDDIITFNPLGKDEAYEIVKLLFKD
CCHHCCCEECCCCCCHHHHHHHHHHHHCCHHHHHHHHHHEECCCCCCHHHHHHHHHHHHH
LQMSLENKGIKASLSENAALLIAKDGFDPDFGARPLRRAIYDLIEDKLSDMILADELHEN
HHHHHHCCCCEEECCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
DNILIDAENDEIVIKKIQI
CCEEEECCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10688204 [H]