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The map label for this gene is atpA [H]

Identifier: 153952146

GI number: 153952146

Start: 113361

End: 114866

Strand: Direct

Name: atpA [H]

Synonym: JJD26997_0112

Alternate gene names: 153952146

Gene position: 113361-114866 (Clockwise)

Preceding gene: 153951608

Following gene: 153952196

Centisome position: 6.14

GC content: 35.52

Gene sequence:

>1506_bases
ATGAAATTTAAAGCTGATGAGATCAGTTCAATAATCAAAGAAAGAATTGAAAATTTTGATTTAAATCTTGAAATTGAAGA
AACAGGAAAGATTATTTCTGTAGCTGATGGTGTTGCTAAGGTATATGGACTTAAGAATATTATGGCTGGAGAAATGGTAG
AATTTGAAAATGGTGATAAAGGAATGGCCTTAAACCTTGAAGAATCGAGTGTAGGTATTGTTATACTTGGAAAAGGAGAA
GGTTTAAAAGAAGGTGCTTCTGTAAAAAGACTTAAGAAATTACTTAAAGTTCCGGTAGGTGAGGCTTTGATTGGTCGTGT
TGTAAATGCTTTAGGTGAACCAATTGATGCTAAAGGCGTGGTCAATGCTAATGAATATCGTTTTGTTGAAGAAAAAGCAA
AAGGTATTATGGCTAGAAAAAGTGTTCATGAGCCTTTGCATACAGGAATTAAAGCTATTGATGCGCTTGTGCCAATTGGT
CGTGGTCAAAGAGAGCTTATCATAGGTGATAGACAAACAGGTAAAACTACTGTTGCCGTTGATACTATTATATCTCAAAG
AGGTCAAGGAGTTATCTGTATATATGTTGCAATTGGTCAAAAGCAAAGTACAGTAGCACAAGTGGTTAAAAGACTAGAAG
AACATGGTGCTATGGAATATACTATTGTTGTAAATGCTGGTGCTTCAGATCCTGCGGCTTTACAGTACTTAGCTCCATAT
GCTGGTGTAACTATGGGTGAATTTTTTAGAGACAATGCAAAACATGCTTTAATTGTTTATGATGATTTGAGTAAGCATGC
TGTAGCTTATCGCGAAATGTCTCTGATTTTACGTCGTCCCCCAGGTCGTGAAGCTTATCCAGGCGATGTTTTTTATCTTC
ATTCAAGATTACTTGAAAGAGCAAGCAAGCTAAATGATGAATTAGGTGCTGGTTCTTTGACAGCACTACCGATAATCGAA
ACACAAGCAGGAGATGTTTCTGCTTATATTCCAACTAATGTTATTTCAATTACTGATGGGCAAATTTTCTTAGAAACTGA
TTTATTTAACTCAGGAATTCGTCCCGCAATTAATGTTGGTTTATCGGTATCTCGTGTAGGTGGGGCTGCTCAAATTAAAG
CTACAAAACAAGTTTCAGGCACATTAAGACTTGATCTTGCTCAATATAGAGAGCTTCAAGCTTTTACACAATTTGCAAGT
GATTTGGATGAGGCAAGTAGAAAACAACTTGAACGTGGGCAAAGAATGGTTGAACTCTTAAAACAACCGCCTTACTCTCC
GCTTAGCGTTGAAAAACAAGTAGTTTTAATTTTTGCAGGAACCAAAGGTTTCTTAGATGATATTGCTGTTTCTAGGATTA
AAGAATTTGAAGATGGAATTTATCCTTTTATCGAGGCAAAACATCCAGATATTTTTGAACAAATCCGCTCTAAAAAAGCT
TTAGATTCTGATTTGGAAGAAAAACTAGCTAAAGCCATTAATGAGTTTAAAGCAAATCATTTATAA

Upstream 100 bases:

>100_bases
GAATTGGAAGAATTAGGTTATGAACTTTCTTTTTCTATGAAAGCTCTTCAAAATAAGCTAAATGAATATGTATTGAAAAT
TATCTAAGGAGAAAAAGTAA

Downstream 100 bases:

>100_bases
GGTCTTTTATGTCTAATTTAAAAGAAATTAAAAGAAAAATTAAAAGTGTTCATAACACTCAAAAGACTACAAATGCTATG
AAGCTAGTTTCTACTGCTAA

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha [H]

Number of amino acids: Translated: 501; Mature: 501

Protein sequence:

>501_residues
MKFKADEISSIIKERIENFDLNLEIEETGKIISVADGVAKVYGLKNIMAGEMVEFENGDKGMALNLEESSVGIVILGKGE
GLKEGASVKRLKKLLKVPVGEALIGRVVNALGEPIDAKGVVNANEYRFVEEKAKGIMARKSVHEPLHTGIKAIDALVPIG
RGQRELIIGDRQTGKTTVAVDTIISQRGQGVICIYVAIGQKQSTVAQVVKRLEEHGAMEYTIVVNAGASDPAALQYLAPY
AGVTMGEFFRDNAKHALIVYDDLSKHAVAYREMSLILRRPPGREAYPGDVFYLHSRLLERASKLNDELGAGSLTALPIIE
TQAGDVSAYIPTNVISITDGQIFLETDLFNSGIRPAINVGLSVSRVGGAAQIKATKQVSGTLRLDLAQYRELQAFTQFAS
DLDEASRKQLERGQRMVELLKQPPYSPLSVEKQVVLIFAGTKGFLDDIAVSRIKEFEDGIYPFIEAKHPDIFEQIRSKKA
LDSDLEEKLAKAINEFKANHL

Sequences:

>Translated_501_residues
MKFKADEISSIIKERIENFDLNLEIEETGKIISVADGVAKVYGLKNIMAGEMVEFENGDKGMALNLEESSVGIVILGKGE
GLKEGASVKRLKKLLKVPVGEALIGRVVNALGEPIDAKGVVNANEYRFVEEKAKGIMARKSVHEPLHTGIKAIDALVPIG
RGQRELIIGDRQTGKTTVAVDTIISQRGQGVICIYVAIGQKQSTVAQVVKRLEEHGAMEYTIVVNAGASDPAALQYLAPY
AGVTMGEFFRDNAKHALIVYDDLSKHAVAYREMSLILRRPPGREAYPGDVFYLHSRLLERASKLNDELGAGSLTALPIIE
TQAGDVSAYIPTNVISITDGQIFLETDLFNSGIRPAINVGLSVSRVGGAAQIKATKQVSGTLRLDLAQYRELQAFTQFAS
DLDEASRKQLERGQRMVELLKQPPYSPLSVEKQVVLIFAGTKGFLDDIAVSRIKEFEDGIYPFIEAKHPDIFEQIRSKKA
LDSDLEEKLAKAINEFKANHL
>Mature_501_residues
MKFKADEISSIIKERIENFDLNLEIEETGKIISVADGVAKVYGLKNIMAGEMVEFENGDKGMALNLEESSVGIVILGKGE
GLKEGASVKRLKKLLKVPVGEALIGRVVNALGEPIDAKGVVNANEYRFVEEKAKGIMARKSVHEPLHTGIKAIDALVPIG
RGQRELIIGDRQTGKTTVAVDTIISQRGQGVICIYVAIGQKQSTVAQVVKRLEEHGAMEYTIVVNAGASDPAALQYLAPY
AGVTMGEFFRDNAKHALIVYDDLSKHAVAYREMSLILRRPPGREAYPGDVFYLHSRLLERASKLNDELGAGSLTALPIIE
TQAGDVSAYIPTNVISITDGQIFLETDLFNSGIRPAINVGLSVSRVGGAAQIKATKQVSGTLRLDLAQYRELQAFTQFAS
DLDEASRKQLERGQRMVELLKQPPYSPLSVEKQVVLIFAGTKGFLDDIAVSRIKEFEDGIYPFIEAKHPDIFEQIRSKKA
LDSDLEEKLAKAINEFKANHL

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit [H]

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI50345984, Length=500, Percent_Identity=61.6, Blast_Score=632, Evalue=0.0,
Organism=Homo sapiens, GI4757810, Length=500, Percent_Identity=61.6, Blast_Score=632, Evalue=0.0,
Organism=Homo sapiens, GI19913428, Length=406, Percent_Identity=29.3103448275862, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI19913426, Length=291, Percent_Identity=29.553264604811, Blast_Score=120, Evalue=4e-27,
Organism=Homo sapiens, GI32189394, Length=443, Percent_Identity=24.3792325056433, Blast_Score=105, Evalue=9e-23,
Organism=Homo sapiens, GI19913424, Length=251, Percent_Identity=26.6932270916335, Blast_Score=79, Evalue=8e-15,
Organism=Escherichia coli, GI1790172, Length=511, Percent_Identity=56.5557729941292, Blast_Score=596, Evalue=1e-171,
Organism=Escherichia coli, GI1790170, Length=441, Percent_Identity=24.7165532879819, Blast_Score=126, Evalue=4e-30,
Organism=Escherichia coli, GI1788251, Length=322, Percent_Identity=27.639751552795, Blast_Score=106, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI71988063, Length=502, Percent_Identity=60.5577689243028, Blast_Score=617, Evalue=1e-177,
Organism=Caenorhabditis elegans, GI71988080, Length=502, Percent_Identity=60.5577689243028, Blast_Score=615, Evalue=1e-176,
Organism=Caenorhabditis elegans, GI71988074, Length=502, Percent_Identity=57.3705179282869, Blast_Score=570, Evalue=1e-163,
Organism=Caenorhabditis elegans, GI17570191, Length=289, Percent_Identity=30.7958477508651, Blast_Score=124, Evalue=9e-29,
Organism=Caenorhabditis elegans, GI17510931, Length=289, Percent_Identity=29.0657439446367, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI25144756, Length=397, Percent_Identity=23.1738035264484, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71988068, Length=71, Percent_Identity=54.9295774647887, Blast_Score=89, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=66, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17565854, Length=247, Percent_Identity=27.1255060728745, Blast_Score=73, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6319370, Length=506, Percent_Identity=60.0790513833992, Blast_Score=619, Evalue=1e-178,
Organism=Saccharomyces cerevisiae, GI6319603, Length=290, Percent_Identity=31.0344827586207, Blast_Score=127, Evalue=5e-30,
Organism=Saccharomyces cerevisiae, GI6322581, Length=424, Percent_Identity=24.2924528301887, Blast_Score=107, Evalue=6e-24,
Organism=Drosophila melanogaster, GI24658560, Length=506, Percent_Identity=59.4861660079051, Blast_Score=608, Evalue=1e-174,
Organism=Drosophila melanogaster, GI281361666, Length=291, Percent_Identity=29.553264604811, Blast_Score=129, Evalue=3e-30,
Organism=Drosophila melanogaster, GI24646341, Length=291, Percent_Identity=29.553264604811, Blast_Score=129, Evalue=3e-30,
Organism=Drosophila melanogaster, GI17136796, Length=291, Percent_Identity=29.553264604811, Blast_Score=129, Evalue=3e-30,
Organism=Drosophila melanogaster, GI28574560, Length=445, Percent_Identity=26.2921348314607, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24638766, Length=395, Percent_Identity=23.7974683544304, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24583992, Length=251, Percent_Identity=26.2948207171315, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI20129479, Length=241, Percent_Identity=29.4605809128631, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24583988, Length=251, Percent_Identity=26.2948207171315, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24583986, Length=251, Percent_Identity=26.2948207171315, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24583984, Length=251, Percent_Identity=26.2948207171315, Blast_Score=77, Evalue=4e-14,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 54788; Mature: 54788

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFKADEISSIIKERIENFDLNLEIEETGKIISVADGVAKVYGLKNIMAGEMVEFENGDK
CCCCHHHHHHHHHHHHHCCCCEEEECCCCCEEEEHHHHHHHHHHHHHHHCCEEEECCCCC
GMALNLEESSVGIVILGKGEGLKEGASVKRLKKLLKVPVGEALIGRVVNALGEPIDAKGV
CEEEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCC
VNANEYRFVEEKAKGIMARKSVHEPLHTGIKAIDALVPIGRGQRELIIGDRQTGKTTVAV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEH
DTIISQRGQGVICIYVAIGQKQSTVAQVVKRLEEHGAMEYTIVVNAGASDPAALQYLAPY
HHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHH
AGVTMGEFFRDNAKHALIVYDDLSKHAVAYREMSLILRRPPGREAYPGDVFYLHSRLLER
CCCHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
ASKLNDELGAGSLTALPIIETQAGDVSAYIPTNVISITDGQIFLETDLFNSGIRPAINVG
HHHHCHHCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEECCCCCCCCHHHHCC
LSVSRVGGAAQIKATKQVSGTLRLDLAQYRELQAFTQFASDLDEASRKQLERGQRMVELL
EEEECCCCCEEEEEHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KQPPYSPLSVEKQVVLIFAGTKGFLDDIAVSRIKEFEDGIYPFIEAKHPDIFEQIRSKKA
HCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHH
LDSDLEEKLAKAINEFKANHL
HCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKFKADEISSIIKERIENFDLNLEIEETGKIISVADGVAKVYGLKNIMAGEMVEFENGDK
CCCCHHHHHHHHHHHHHCCCCEEEECCCCCEEEEHHHHHHHHHHHHHHHCCEEEECCCCC
GMALNLEESSVGIVILGKGEGLKEGASVKRLKKLLKVPVGEALIGRVVNALGEPIDAKGV
CEEEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCC
VNANEYRFVEEKAKGIMARKSVHEPLHTGIKAIDALVPIGRGQRELIIGDRQTGKTTVAV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEH
DTIISQRGQGVICIYVAIGQKQSTVAQVVKRLEEHGAMEYTIVVNAGASDPAALQYLAPY
HHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHH
AGVTMGEFFRDNAKHALIVYDDLSKHAVAYREMSLILRRPPGREAYPGDVFYLHSRLLER
CCCHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
ASKLNDELGAGSLTALPIIETQAGDVSAYIPTNVISITDGQIFLETDLFNSGIRPAINVG
HHHHCHHCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEECCCCCCCCHHHHCC
LSVSRVGGAAQIKATKQVSGTLRLDLAQYRELQAFTQFASDLDEASRKQLERGQRMVELL
EEEECCCCCEEEEEHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KQPPYSPLSVEKQVVLIFAGTKGFLDDIAVSRIKEFEDGIYPFIEAKHPDIFEQIRSKKA
HCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHH
LDSDLEEKLAKAINEFKANHL
HCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA