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The map label for this gene is argD [H]

Identifier: 153952018

GI number: 153952018

Start: 210601

End: 211782

Strand: Direct

Name: argD [H]

Synonym: JJD26997_0225

Alternate gene names: 153952018

Gene position: 210601-211782 (Clockwise)

Preceding gene: 153952612

Following gene: 153951954

Centisome position: 11.41

GC content: 33.25

Gene sequence:

>1182_bases
ATGGATTATAAGGAACAAAGTCATATTATCCCTACTTATAAGCGTTTTGATATAGTTTTAGAAAAAGGGCAGGGGGTTTA
TCTTTTTGATGATAAGGCTAAAAAATATCTTGATTTTTCAAGTGGTATAGGCGTTTGTGCTTTAGGATATAATCATGCTA
AATTTAATGCTAAAATCAAAGCTCAAGTGGATAAACTTTTACATACTAGCAATTTATATTATAATGAAAACATAGCCACT
GCAGCTAAAAATTTAGCCAAAGCTAGTGCTTTAGAGCGTGTTTTTTTTACAAATTCTGGTACAGAAAGTATAGAAGGAGC
GATGAAAACAGCTAGAAAGTACGCCTTTAACAAAGGTATTAAGGGCGGACAATTTATCGCTTTTAAGCATTCTTTTCATG
GGCGTACTTTAGGGGCTTTATCGCTTACTGCTAATGAAAAATATCAAAAGCCTTTTAAACCTTTAATTTCAGGGGTTAAA
TTTGCAAAATATAATGATATTTCAAGCGTTGAAAAACGAGTAAATGAAAAAACTTGCGCCATTATCTTAGAAAGCGTGCA
AGGAGAAGGTGGAATAAATCCTGCAAATAAAGATTTTTACAAAGCCTTAAGAAAGCTTTGCGATGAAAAAGATATATTAT
TAATCGCTGATGAAATTCAATGTGGTATGGGTAGAAGTGGAAAATTTTTTGCCTATGAGCACGCACAAATTTTGCCTGAT
ATCATGACTTCGGCTAAGGCCTTAGGTTGTGGGCTTAGCGTGGGTGCTTTTGTAATAAATCAAAAGGTAGCAAGCAATTC
TTTAGAAGCGGGTGATCATGGAAGTACTTATGGGGGAAATCCTTTGGTTTGTGCAGGAGTGAATGCGGTTTTTGAAATTT
TTAAAGAAGAAAAAATTTTAGAAAATGTCAATAAACTCATGCCTTATTTAGAGCAAAGTTTAGATGAGTTGATCAAAGAA
TTTGATTTTTGTAAAAAACGCAAAGGCTTAGGGTTTATGCAAGGCTTAAGTCTTGATAAAAGTGTAAAAGTAGCTAAGGT
CATTCAAAAATGCCAAGAAAATGCACTTTTACTGATAAGTTGCGGGGAGAATGATTTGAGATTTTTACCTCCTTTGATTT
TGCAAAAAGAACATATTGATGAAATGAGTGAAAAGTTAAGAAAGGCTCTAAAGAGTTTTTAA

Upstream 100 bases:

>100_bases
TAAAAAGGTGCATATTTTAGATGGGCGTGTAAAGCATTCTTTATTGCTTGAGTTTTTTACCGATGAAGGTATAGGCACTT
TGGTGGGTTAAAGGGTGAAA

Downstream 100 bases:

>100_bases
TAAATTTTGTAAAAAAGTTTATTCTTTTCCATCTACTATAGGCACAAATAAACATTCTTCTAAAGTTTCTTTCTGTAAAT
TTGTGCCATTTTTTCTAAGG

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MDYKEQSHIIPTYKRFDIVLEKGQGVYLFDDKAKKYLDFSSGIGVCALGYNHAKFNAKIKAQVDKLLHTSNLYYNENIAT
AAKNLAKASALERVFFTNSGTESIEGAMKTARKYAFNKGIKGGQFIAFKHSFHGRTLGALSLTANEKYQKPFKPLISGVK
FAKYNDISSVEKRVNEKTCAIILESVQGEGGINPANKDFYKALRKLCDEKDILLIADEIQCGMGRSGKFFAYEHAQILPD
IMTSAKALGCGLSVGAFVINQKVASNSLEAGDHGSTYGGNPLVCAGVNAVFEIFKEEKILENVNKLMPYLEQSLDELIKE
FDFCKKRKGLGFMQGLSLDKSVKVAKVIQKCQENALLLISCGENDLRFLPPLILQKEHIDEMSEKLRKALKSF

Sequences:

>Translated_393_residues
MDYKEQSHIIPTYKRFDIVLEKGQGVYLFDDKAKKYLDFSSGIGVCALGYNHAKFNAKIKAQVDKLLHTSNLYYNENIAT
AAKNLAKASALERVFFTNSGTESIEGAMKTARKYAFNKGIKGGQFIAFKHSFHGRTLGALSLTANEKYQKPFKPLISGVK
FAKYNDISSVEKRVNEKTCAIILESVQGEGGINPANKDFYKALRKLCDEKDILLIADEIQCGMGRSGKFFAYEHAQILPD
IMTSAKALGCGLSVGAFVINQKVASNSLEAGDHGSTYGGNPLVCAGVNAVFEIFKEEKILENVNKLMPYLEQSLDELIKE
FDFCKKRKGLGFMQGLSLDKSVKVAKVIQKCQENALLLISCGENDLRFLPPLILQKEHIDEMSEKLRKALKSF
>Mature_393_residues
MDYKEQSHIIPTYKRFDIVLEKGQGVYLFDDKAKKYLDFSSGIGVCALGYNHAKFNAKIKAQVDKLLHTSNLYYNENIAT
AAKNLAKASALERVFFTNSGTESIEGAMKTARKYAFNKGIKGGQFIAFKHSFHGRTLGALSLTANEKYQKPFKPLISGVK
FAKYNDISSVEKRVNEKTCAIILESVQGEGGINPANKDFYKALRKLCDEKDILLIADEIQCGMGRSGKFFAYEHAQILPD
IMTSAKALGCGLSVGAFVINQKVASNSLEAGDHGSTYGGNPLVCAGVNAVFEIFKEEKILENVNKLMPYLEQSLDELIKE
FDFCKKRKGLGFMQGLSLDKSVKVAKVIQKCQENALLLISCGENDLRFLPPLILQKEHIDEMSEKLRKALKSF

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=398, Percent_Identity=32.1608040201005, Blast_Score=218, Evalue=6e-57,
Organism=Homo sapiens, GI284507298, Length=302, Percent_Identity=32.1192052980132, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI13994255, Length=442, Percent_Identity=28.0542986425339, Blast_Score=163, Evalue=3e-40,
Organism=Homo sapiens, GI226442705, Length=430, Percent_Identity=27.4418604651163, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI37574042, Length=430, Percent_Identity=27.4418604651163, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI24119277, Length=408, Percent_Identity=24.7549019607843, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI226442709, Length=367, Percent_Identity=27.5204359673025, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI188536080, Length=414, Percent_Identity=25.1207729468599, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI38679950, Length=414, Percent_Identity=25.1207729468599, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI38679946, Length=414, Percent_Identity=25.1207729468599, Blast_Score=96, Evalue=6e-20,
Organism=Escherichia coli, GI1788044, Length=388, Percent_Identity=36.340206185567, Blast_Score=282, Evalue=3e-77,
Organism=Escherichia coli, GI1789759, Length=388, Percent_Identity=36.5979381443299, Blast_Score=281, Evalue=7e-77,
Organism=Escherichia coli, GI145693181, Length=380, Percent_Identity=33.1578947368421, Blast_Score=194, Evalue=6e-51,
Organism=Escherichia coli, GI1787560, Length=400, Percent_Identity=32.25, Blast_Score=183, Evalue=2e-47,
Organism=Escherichia coli, GI1789016, Length=394, Percent_Identity=30.2030456852792, Blast_Score=173, Evalue=2e-44,
Organism=Escherichia coli, GI1786991, Length=415, Percent_Identity=28.6746987951807, Blast_Score=145, Evalue=6e-36,
Organism=Escherichia coli, GI1786349, Length=324, Percent_Identity=29.6296296296296, Blast_Score=105, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI25144271, Length=386, Percent_Identity=32.6424870466321, Blast_Score=221, Evalue=4e-58,
Organism=Caenorhabditis elegans, GI25144274, Length=383, Percent_Identity=28.7206266318538, Blast_Score=166, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI32564660, Length=441, Percent_Identity=28.3446712018141, Blast_Score=160, Evalue=8e-40,
Organism=Caenorhabditis elegans, GI71992977, Length=412, Percent_Identity=25.4854368932039, Blast_Score=124, Evalue=7e-29,
Organism=Caenorhabditis elegans, GI17541228, Length=440, Percent_Identity=25, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI71981843, Length=160, Percent_Identity=28.75, Blast_Score=86, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6324432, Length=406, Percent_Identity=38.423645320197, Blast_Score=276, Evalue=4e-75,
Organism=Saccharomyces cerevisiae, GI6323470, Length=399, Percent_Identity=28.8220551378446, Blast_Score=177, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6324386, Length=423, Percent_Identity=25.0591016548463, Blast_Score=110, Evalue=6e-25,
Organism=Saccharomyces cerevisiae, GI6321456, Length=426, Percent_Identity=25.3521126760563, Blast_Score=91, Evalue=2e-19,
Organism=Drosophila melanogaster, GI21357415, Length=386, Percent_Identity=32.3834196891192, Blast_Score=221, Evalue=7e-58,
Organism=Drosophila melanogaster, GI161085790, Length=443, Percent_Identity=28.6681715575621, Blast_Score=170, Evalue=2e-42,
Organism=Drosophila melanogaster, GI28574759, Length=426, Percent_Identity=28.4037558685446, Blast_Score=164, Evalue=8e-41,
Organism=Drosophila melanogaster, GI21356575, Length=422, Percent_Identity=26.303317535545, Blast_Score=136, Evalue=3e-32,
Organism=Drosophila melanogaster, GI281366494, Length=428, Percent_Identity=26.8691588785047, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24667139, Length=428, Percent_Identity=26.8691588785047, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24667143, Length=428, Percent_Identity=26.8691588785047, Blast_Score=123, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 43651; Mature: 43651

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYKEQSHIIPTYKRFDIVLEKGQGVYLFDDKAKKYLDFSSGIGVCALGYNHAKFNAKIK
CCCCCCCCCCCCHHHEEEEEECCCEEEEECCCHHHHHCCCCCCCEEEECCCCCEECCHHH
AQVDKLLHTSNLYYNENIATAAKNLAKASALERVFFTNSGTESIEGAMKTARKYAFNKGI
HHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCC
KGGQFIAFKHSFHGRTLGALSLTANEKYQKPFKPLISGVKFAKYNDISSVEKRVNEKTCA
CCCEEEEEEECCCCCEEEEEEECCCHHHCCHHHHHHCCCCHHCCCCHHHHHHHHCHHHHH
IILESVQGEGGINPANKDFYKALRKLCDEKDILLIADEIQCGMGRSGKFFAYEHAQILPD
HHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCEEEEHHHHHHHH
IMTSAKALGCGLSVGAFVINQKVASNSLEAGDHGSTYGGNPLVCAGVNAVFEIFKEEKIL
HHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHH
ENVNKLMPYLEQSLDELIKEFDFCKKRKGLGFMQGLSLDKSVKVAKVIQKCQENALLLIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCHHHHHHHHHHCCCCEEEEE
CGENDLRFLPPLILQKEHIDEMSEKLRKALKSF
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDYKEQSHIIPTYKRFDIVLEKGQGVYLFDDKAKKYLDFSSGIGVCALGYNHAKFNAKIK
CCCCCCCCCCCCHHHEEEEEECCCEEEEECCCHHHHHCCCCCCCEEEECCCCCEECCHHH
AQVDKLLHTSNLYYNENIATAAKNLAKASALERVFFTNSGTESIEGAMKTARKYAFNKGI
HHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCC
KGGQFIAFKHSFHGRTLGALSLTANEKYQKPFKPLISGVKFAKYNDISSVEKRVNEKTCA
CCCEEEEEEECCCCCEEEEEEECCCHHHCCHHHHHHCCCCHHCCCCHHHHHHHHCHHHHH
IILESVQGEGGINPANKDFYKALRKLCDEKDILLIADEIQCGMGRSGKFFAYEHAQILPD
HHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCEEEEHHHHHHHH
IMTSAKALGCGLSVGAFVINQKVASNSLEAGDHGSTYGGNPLVCAGVNAVFEIFKEEKIL
HHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHH
ENVNKLMPYLEQSLDELIKEFDFCKKRKGLGFMQGLSLDKSVKVAKVIQKCQENALLLIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCHHHHHHHHHHCCCCEEEEE
CGENDLRFLPPLILQKEHIDEMSEKLRKALKSF
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10588044; 10688204 [H]