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The map label for this gene is oxaA [H]

Identifier: 153951835

GI number: 153951835

Start: 740550

End: 742142

Strand: Direct

Name: oxaA [H]

Synonym: JJD26997_0823

Alternate gene names: 153951835

Gene position: 740550-742142 (Clockwise)

Preceding gene: 153951899

Following gene: 153951735

Centisome position: 40.14

GC content: 31.07

Gene sequence:

>1593_bases
GTGAATAATTCAAATAATATTTTTCAGCAAAAGCGTATACTTTTGGCTGTTGTGATTTCTTTTTTATTTTTTGTTGTTTA
TGATTATTTTTTCATTCCAAAGCAACCTTTAAAAATAGAACAAAACATTACACAACAAAATCAACAAAACACAAGTATAA
ATAACATTCCTAATATACAAAATACCACCACAAATACTCCAAGTGCGGCTTTAGTTTCGCAAGATAGTATGATATCTAAG
GTTCAAAGCAAACATTTTGAAGCACAAATTGACTCTTTTGGTAGAATTTCTGCTTTTTATTTGAAAGATAAAAAATACCA
AAATGAGAAAGGAGAATTTATAAATCTTGTCAGTAAGGAAAATAGTCCTTATCCTTTAGAAATGCGTTTTAGCGATCCAA
GTATTAACTCAGAGGCTTTTAAAATTCCTTATGCCGCTAATGCTAATAATCTTTTTGTTGATGAAAATGGAAGTCAAGTT
TTAAAACTCACCCAAAATCTTTCTGGATTGAAAATCGAAAAAGATATTACTTTTTATGCAAAAGGAAATTATGAGATAGA
AGTTAAACTCAGCAAGAATGCAAATTATTTTATAAGTCCAGGATATCGTCCAAATATTGCTGTAGATAGCTATACAGTTC
ATGGTGCTTTGGTAGTGGATAATAAAGAAACCATCGAAACTTATAAGGATGGAGATGTAGAAAAGGATGAAAGTGCTAAT
AATGTCGTAATGACTTCGGCTTTTGATAGATACTATGCAAATTTCTTTTATAATTTTGATAAACCTTTAAATGTAGCAAT
CAGCAAAGATGCTAATAAAAACCCTATAGTTTTTGCTTATAGTGATAATGAATTTAAAGCAGGGGGCTATATAGGTTCTA
AAGAACATGTGATTTTAAGAAGTATAGATCCACGCCTTGAAGCAGTTGTTGAATATGGTTGGTTTACTTTTATTGCTAAG
CCTATGTTTGAGTTTTTGAATTTCTTCCATCAGTATATAGGAAATTGGGGTTGGGCTATCGTTGTGATGACTTTAATTGT
GCGTATTATTTTATTCCCACTAACTTATAAGTCTATGATTTCTATGAATAAACTTAAAGATCTTGCTCCTAAAATGAAAG
ATATTAGAGAGCGTTACAAAGGCGATCCGCAGAAAATGAATATGCACATGATGGAGCTTTATAAAAAACATGGTGCAAAT
CCTATGAGTGGTTGTTTGCCTATACTTTTACAAATTCCTATTTTCTTTGCTATTTATCGCGTCTTGCTTAATGCTATTGA
ACTAAAAGCGGCTCCTTGGGCGTTTTGGATACATGATTTATCGGTAATGGACCCTTATTTTATTTTACCTATTTTAATGG
GTGCAACGATGTTTTTACAACAACTTATTACACCTATGACTATACAAGATCCTATGCAAGCTAAGATTATGAAATTTTTA
CCAGTGATTTTTACCTTTTTCTTTATCACTTTCCCAGCAGGACTTACGCTTTATTGGTTTGTAAATAACCTTTGTTCTTT
GGTTCAACAATGGGTTATCAATAAAATATTTGCTAAAGAACATCACAAAAAACAAGCGGAGCATGAAAAATGA

Upstream 100 bases:

>100_bases
AGCCTATGTTTTTAGCAAAAAAACAACTTTGTTTTTTATATATACCTTATAAAAATAAAAGTTTTTATCTTATAAAAATT
ATCTTTAAAAGGACAAATCA

Downstream 100 bases:

>100_bases
AAATCGAAGCCATTGATCTTCAAAGTGCTTTAACAGAAGCTTCAAGAAGTTTAGAATGTTCTGTGATGGACTTAGAATAT
GAGATTATTCAGCATCCAAG

Product: putative inner membrane protein translocase component YidC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 530; Mature: 530

Protein sequence:

>530_residues
MNNSNNIFQQKRILLAVVISFLFFVVYDYFFIPKQPLKIEQNITQQNQQNTSINNIPNIQNTTTNTPSAALVSQDSMISK
VQSKHFEAQIDSFGRISAFYLKDKKYQNEKGEFINLVSKENSPYPLEMRFSDPSINSEAFKIPYAANANNLFVDENGSQV
LKLTQNLSGLKIEKDITFYAKGNYEIEVKLSKNANYFISPGYRPNIAVDSYTVHGALVVDNKETIETYKDGDVEKDESAN
NVVMTSAFDRYYANFFYNFDKPLNVAISKDANKNPIVFAYSDNEFKAGGYIGSKEHVILRSIDPRLEAVVEYGWFTFIAK
PMFEFLNFFHQYIGNWGWAIVVMTLIVRIILFPLTYKSMISMNKLKDLAPKMKDIRERYKGDPQKMNMHMMELYKKHGAN
PMSGCLPILLQIPIFFAIYRVLLNAIELKAAPWAFWIHDLSVMDPYFILPILMGATMFLQQLITPMTIQDPMQAKIMKFL
PVIFTFFFITFPAGLTLYWFVNNLCSLVQQWVINKIFAKEHHKKQAEHEK

Sequences:

>Translated_530_residues
MNNSNNIFQQKRILLAVVISFLFFVVYDYFFIPKQPLKIEQNITQQNQQNTSINNIPNIQNTTTNTPSAALVSQDSMISK
VQSKHFEAQIDSFGRISAFYLKDKKYQNEKGEFINLVSKENSPYPLEMRFSDPSINSEAFKIPYAANANNLFVDENGSQV
LKLTQNLSGLKIEKDITFYAKGNYEIEVKLSKNANYFISPGYRPNIAVDSYTVHGALVVDNKETIETYKDGDVEKDESAN
NVVMTSAFDRYYANFFYNFDKPLNVAISKDANKNPIVFAYSDNEFKAGGYIGSKEHVILRSIDPRLEAVVEYGWFTFIAK
PMFEFLNFFHQYIGNWGWAIVVMTLIVRIILFPLTYKSMISMNKLKDLAPKMKDIRERYKGDPQKMNMHMMELYKKHGAN
PMSGCLPILLQIPIFFAIYRVLLNAIELKAAPWAFWIHDLSVMDPYFILPILMGATMFLQQLITPMTIQDPMQAKIMKFL
PVIFTFFFITFPAGLTLYWFVNNLCSLVQQWVINKIFAKEHHKKQAEHEK
>Mature_530_residues
MNNSNNIFQQKRILLAVVISFLFFVVYDYFFIPKQPLKIEQNITQQNQQNTSINNIPNIQNTTTNTPSAALVSQDSMISK
VQSKHFEAQIDSFGRISAFYLKDKKYQNEKGEFINLVSKENSPYPLEMRFSDPSINSEAFKIPYAANANNLFVDENGSQV
LKLTQNLSGLKIEKDITFYAKGNYEIEVKLSKNANYFISPGYRPNIAVDSYTVHGALVVDNKETIETYKDGDVEKDESAN
NVVMTSAFDRYYANFFYNFDKPLNVAISKDANKNPIVFAYSDNEFKAGGYIGSKEHVILRSIDPRLEAVVEYGWFTFIAK
PMFEFLNFFHQYIGNWGWAIVVMTLIVRIILFPLTYKSMISMNKLKDLAPKMKDIRERYKGDPQKMNMHMMELYKKHGAN
PMSGCLPILLQIPIFFAIYRVLLNAIELKAAPWAFWIHDLSVMDPYFILPILMGATMFLQQLITPMTIQDPMQAKIMKFL
PVIFTFFFITFPAGLTLYWFVNNLCSLVQQWVINKIFAKEHHKKQAEHEK

Specific function: Required for the insertion of integral membrane proteins into the membrane. Probably plays an essential role in the integration of proteins of the respiratory chain complexes. Involved in integration of membrane proteins that insert dependently and indepe

COG id: COG0706

COG function: function code U; Preprotein translocase subunit YidC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OXA1/oxaA family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790140, Length=237, Percent_Identity=46.8354430379747, Blast_Score=257, Evalue=1e-69,
Organism=Drosophila melanogaster, GI24662345, Length=217, Percent_Identity=28.5714285714286, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21356443, Length=217, Percent_Identity=28.5714285714286, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019998
- InterPro:   IPR001708 [H]

Pfam domain/function: PF02096 60KD_IMP [H]

EC number: NA

Molecular weight: Translated: 61255; Mature: 61255

Theoretical pI: Translated: 9.04; Mature: 9.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNSNNIFQQKRILLAVVISFLFFVVYDYFFIPKQPLKIEQNITQQNQQNTSINNIPNIQ
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCC
NTTTNTPSAALVSQDSMISKVQSKHFEAQIDSFGRISAFYLKDKKYQNEKGEFINLVSKE
CCCCCCCCHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCEEEEEECC
NSPYPLEMRFSDPSINSEAFKIPYAANANNLFVDENGSQVLKLTQNLSGLKIEKDITFYA
CCCCCEEEEECCCCCCCCEEECCEECCCCEEEEECCCCHHHHHHCCCCCCEEECCEEEEE
KGNYEIEVKLSKNANYFISPGYRPNIAVDSYTVHGALVVDNKETIETYKDGDVEKDESAN
CCCEEEEEEEECCCCEEECCCCCCCEEEECEEEEEEEEECCHHHHHHHCCCCCCCCCCCC
NVVMTSAFDRYYANFFYNFDKPLNVAISKDANKNPIVFAYSDNEFKAGGYIGSKEHVILR
CEEEEHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEECCCCEECCCCCCCCCCEEEE
SIDPRLEAVVEYGWFTFIAKPMFEFLNFFHQYIGNWGWAIVVMTLIVRIILFPLTYKSMI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
SMNKLKDLAPKMKDIRERYKGDPQKMNMHMMELYKKHGANPMSGCLPILLQIPIFFAIYR
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
VLLNAIELKAAPWAFWIHDLSVMDPYFILPILMGATMFLQQLITPMTIQDPMQAKIMKFL
HHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
PVIFTFFFITFPAGLTLYWFVNNLCSLVQQWVINKIFAKEHHKKQAEHEK
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNNSNNIFQQKRILLAVVISFLFFVVYDYFFIPKQPLKIEQNITQQNQQNTSINNIPNIQ
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCC
NTTTNTPSAALVSQDSMISKVQSKHFEAQIDSFGRISAFYLKDKKYQNEKGEFINLVSKE
CCCCCCCCHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCEEEEEECC
NSPYPLEMRFSDPSINSEAFKIPYAANANNLFVDENGSQVLKLTQNLSGLKIEKDITFYA
CCCCCEEEEECCCCCCCCEEECCEECCCCEEEEECCCCHHHHHHCCCCCCEEECCEEEEE
KGNYEIEVKLSKNANYFISPGYRPNIAVDSYTVHGALVVDNKETIETYKDGDVEKDESAN
CCCEEEEEEEECCCCEEECCCCCCCEEEECEEEEEEEEECCHHHHHHHCCCCCCCCCCCC
NVVMTSAFDRYYANFFYNFDKPLNVAISKDANKNPIVFAYSDNEFKAGGYIGSKEHVILR
CEEEEHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEECCCCEECCCCCCCCCCEEEE
SIDPRLEAVVEYGWFTFIAKPMFEFLNFFHQYIGNWGWAIVVMTLIVRIILFPLTYKSMI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
SMNKLKDLAPKMKDIRERYKGDPQKMNMHMMELYKKHGANPMSGCLPILLQIPIFFAIYR
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
VLLNAIELKAAPWAFWIHDLSVMDPYFILPILMGATMFLQQLITPMTIQDPMQAKIMKFL
HHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
PVIFTFFFITFPAGLTLYWFVNNLCSLVQQWVINKIFAKEHHKKQAEHEK
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10688204 [H]