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The map label for this gene is dcuA [H]

Identifier: 153951706

GI number: 153951706

Start: 99531

End: 100859

Strand: Direct

Name: dcuA [H]

Synonym: JJD26997_0095

Alternate gene names: 153951706

Gene position: 99531-100859 (Clockwise)

Preceding gene: 153952003

Following gene: 153952518

Centisome position: 5.39

GC content: 37.1

Gene sequence:

>1329_bases
ATGATAATTTTGCAAGTAATCGTTCTTCTTGGGGCGATTTTTATTGGTATTCGTCTAGGTGGTATTGCTATAGGTTATGC
TGGAGGATTAGGTGTTGTTGTACTAGGGCTTGTTTTAGGTATGAAACCTGGTAATATTCCTTGGGATGTTATTTTAATTA
TTGCTGCAGCTATTGCGGCAATTTCTGCTATGCAACAAGCAGGTGGACTTGATTATATGGTAAGGGTGACAGAAAAAATT
TTAAGATCAAGCCCTAAATTTATAAATTATTTAGCTCCAGCTTGTGGATGGTTGCTTACAATCTTAGCAGGAACAGGAAA
TGCAGTATTTTCTTTAATGCCTGTTGTAGTTGATGTTGCAAAATCTCAAAACATAAAACCTAGTGTTCCACTTTCATTAA
TGGTTGTTTCTTCGCAAATTGGAATCACTGCTTCTCCTGTGAGTGCAGCTGTGGTTTATATGAGCGGGGTTTTAGAGCCG
CTTGGATGGAATTATCCAACTTTAATTGGAATTTGGATCGGTACAACTTTTATAGCTTGTATGCTTACAGCTTTTATAGT
GAGTTTAATCACTCCTATGGATTTAAGCAAAGATAATGTTTATCAAAAACGCTTAAAAGCAGGACTTGTTAAAGATGCAG
GAGCTATTTTACATGGTGAAGATAAACCAGGTGCTAAACTTTCAGTAGGAATTTTCTTGATCACTGTTTTGGCAGTTGTA
CTTTATGCAACTGCAATTTCAAGTAATATTAAATGGATTGATCCTGTTGTGGTTCCAAGAGATGCAGCTATTATGAGCTT
TTTACTTACTGCAGCAACTTTGATTACTTGGCTTTGCAAAGTTGAACCAGGTAAAATTCTTGATACTAGCGTATTTAAAA
GCGGTATGACTGCTTGTGTTTGCGTTTTTGGTGTAGCATGGCTTGGAAATACTTTTGTTGCAGGACACGAAGCTGCTATT
AAAGAAGTAGCAGGCGACTGGGTTAAACAAACCCCTGCTATGTTAGCAGTTGCATTTTTCTTTGCAAGTATGCTTTTATA
TTCTCAAGCAGCAACCGCAAAGGCCATTGTACCTGTAATTATCACCGCTTTAGGAATTTCAGCAGCAAATCCGCATGATT
CTTATATGCTTGTAGCTTGTTTTGCAGCAGTTTCAGCACTTTTTGTGCTTCCAACTTATCCAACCTTACTTGGCGCTGTA
CAAATGGATGATACAGGAACGACTAGAATTGGTAAATTTATATTTAACCACTCTTTCTTTATACCAGGAGTTTTAGCTAT
TGCAATTGCTGTAGCATTAGGCTTTGTATTAGCTCCTATGCTTATTTAA

Upstream 100 bases:

>100_bases
TTAAGTAAAGAACAAATTGATGAAATTTTAACTCCATCAAATATGCTAAATCCTCACATGAAAGCTAAAAAATAGCATTT
TAGGATTTAATATGGATATA

Downstream 100 bases:

>100_bases
ATCAAACCCTAGGTTTTTCCTCCTAGGGTTAAATTTTTTCATTAGTTTTTAAGTATATACTACGCTATAATATTTTTAAA
ATTTATTGTTAATAATTTAT

Product: anaerobic C4-dicarboxylate transporter

Products: C4-dicarboxylates [Periplasm]; C4-dicarboxylates [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 442; Mature: 442

Protein sequence:

>442_residues
MIILQVIVLLGAIFIGIRLGGIAIGYAGGLGVVVLGLVLGMKPGNIPWDVILIIAAAIAAISAMQQAGGLDYMVRVTEKI
LRSSPKFINYLAPACGWLLTILAGTGNAVFSLMPVVVDVAKSQNIKPSVPLSLMVVSSQIGITASPVSAAVVYMSGVLEP
LGWNYPTLIGIWIGTTFIACMLTAFIVSLITPMDLSKDNVYQKRLKAGLVKDAGAILHGEDKPGAKLSVGIFLITVLAVV
LYATAISSNIKWIDPVVVPRDAAIMSFLLTAATLITWLCKVEPGKILDTSVFKSGMTACVCVFGVAWLGNTFVAGHEAAI
KEVAGDWVKQTPAMLAVAFFFASMLLYSQAATAKAIVPVIITALGISAANPHDSYMLVACFAAVSALFVLPTYPTLLGAV
QMDDTGTTRIGKFIFNHSFFIPGVLAIAIAVALGFVLAPMLI

Sequences:

>Translated_442_residues
MIILQVIVLLGAIFIGIRLGGIAIGYAGGLGVVVLGLVLGMKPGNIPWDVILIIAAAIAAISAMQQAGGLDYMVRVTEKI
LRSSPKFINYLAPACGWLLTILAGTGNAVFSLMPVVVDVAKSQNIKPSVPLSLMVVSSQIGITASPVSAAVVYMSGVLEP
LGWNYPTLIGIWIGTTFIACMLTAFIVSLITPMDLSKDNVYQKRLKAGLVKDAGAILHGEDKPGAKLSVGIFLITVLAVV
LYATAISSNIKWIDPVVVPRDAAIMSFLLTAATLITWLCKVEPGKILDTSVFKSGMTACVCVFGVAWLGNTFVAGHEAAI
KEVAGDWVKQTPAMLAVAFFFASMLLYSQAATAKAIVPVIITALGISAANPHDSYMLVACFAAVSALFVLPTYPTLLGAV
QMDDTGTTRIGKFIFNHSFFIPGVLAIAIAVALGFVLAPMLI
>Mature_442_residues
MIILQVIVLLGAIFIGIRLGGIAIGYAGGLGVVVLGLVLGMKPGNIPWDVILIIAAAIAAISAMQQAGGLDYMVRVTEKI
LRSSPKFINYLAPACGWLLTILAGTGNAVFSLMPVVVDVAKSQNIKPSVPLSLMVVSSQIGITASPVSAAVVYMSGVLEP
LGWNYPTLIGIWIGTTFIACMLTAFIVSLITPMDLSKDNVYQKRLKAGLVKDAGAILHGEDKPGAKLSVGIFLITVLAVV
LYATAISSNIKWIDPVVVPRDAAIMSFLLTAATLITWLCKVEPGKILDTSVFKSGMTACVCVFGVAWLGNTFVAGHEAAI
KEVAGDWVKQTPAMLAVAFFFASMLLYSQAATAKAIVPVIITALGISAANPHDSYMLVACFAAVSALFVLPTYPTLLGAV
QMDDTGTTRIGKFIFNHSFFIPGVLAIAIAVALGFVLAPMLI

Specific function: Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane [H]

COG id: COG2704

COG function: function code R; Anaerobic C4-dicarboxylate transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dcuA/dcuB transporter (TC 2.A.13.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790580, Length=442, Percent_Identity=53.8461538461538, Blast_Score=412, Evalue=1e-116,
Organism=Escherichia coli, GI1790565, Length=418, Percent_Identity=35.4066985645933, Blast_Score=214, Evalue=7e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004668 [H]

Pfam domain/function: PF03605 DcuA_DcuB [H]

EC number: NA

Molecular weight: Translated: 46342; Mature: 46342

Theoretical pI: Translated: 8.75; Mature: 8.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIILQVIVLLGAIFIGIRLGGIAIGYAGGLGVVVLGLVLGMKPGNIPWDVILIIAAAIAA
CHHHHHHHHHHHHHHHHHHHCEEEECCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
ISAMQQAGGLDYMVRVTEKILRSSPKFINYLAPACGWLLTILAGTGNAVFSLMPVVVDVA
HHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
KSQNIKPSVPLSLMVVSSQIGITASPVSAAVVYMSGVLEPLGWNYPTLIGIWIGTTFIAC
HCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
MLTAFIVSLITPMDLSKDNVYQKRLKAGLVKDAGAILHGEDKPGAKLSVGIFLITVLAVV
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHHH
LYATAISSNIKWIDPVVVPRDAAIMSFLLTAATLITWLCKVEPGKILDTSVFKSGMTACV
HHHHHHHCCCCEECCEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
CVFGVAWLGNTFVAGHEAAIKEVAGDWVKQTPAMLAVAFFFASMLLYSQAATAKAIVPVI
HHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITALGISAANPHDSYMLVACFAAVSALFVLPTYPTLLGAVQMDDTGTTRIGKFIFNHSFF
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHEEEECCCCHHHHHHHHHCCCCH
IPGVLAIAIAVALGFVLAPMLI
HHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIILQVIVLLGAIFIGIRLGGIAIGYAGGLGVVVLGLVLGMKPGNIPWDVILIIAAAIAA
CHHHHHHHHHHHHHHHHHHHCEEEECCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
ISAMQQAGGLDYMVRVTEKILRSSPKFINYLAPACGWLLTILAGTGNAVFSLMPVVVDVA
HHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
KSQNIKPSVPLSLMVVSSQIGITASPVSAAVVYMSGVLEPLGWNYPTLIGIWIGTTFIAC
HCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
MLTAFIVSLITPMDLSKDNVYQKRLKAGLVKDAGAILHGEDKPGAKLSVGIFLITVLAVV
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHHH
LYATAISSNIKWIDPVVVPRDAAIMSFLLTAATLITWLCKVEPGKILDTSVFKSGMTACV
HHHHHHHCCCCEECCEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
CVFGVAWLGNTFVAGHEAAIKEVAGDWVKQTPAMLAVAFFFASMLLYSQAATAKAIVPVI
HHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITALGISAANPHDSYMLVACFAAVSALFVLPTYPTLLGAVQMDDTGTTRIGKFIFNHSFF
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHEEEECCCCHHHHHHHHHCCCCH
IPGVLAIAIAVALGFVLAPMLI
HHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: C4-dicarboxylates [Periplasm]; C4-dicarboxylates [Periplasm] [C]

Specific reaction: C4-dicarboxylates [Periplasm] + C4-dicarboxylates [Periplasm] = C4-dicarboxylates [Periplasm] + C4-dicarboxylates [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]