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The map label for this gene is yleA [C]

Identifier: 153951587

GI number: 153951587

Start: 708502

End: 709752

Strand: Direct

Name: yleA [C]

Synonym: JJD26997_0783

Alternate gene names: 153951587

Gene position: 708502-709752 (Clockwise)

Preceding gene: 153952566

Following gene: 153952493

Centisome position: 38.4

GC content: 31.49

Gene sequence:

>1251_bases
TTGAAAGAAAAAGTTTTCTTTAAAACCTTTGGGTGTCGCACAAATATTTATGATACAGAGCTTTTAAAAAGTTATGTAAA
AGATTATGAGATTATAAATGATGAGAATAAAGCACAAATTATCGTTGTAAATTCTTGCACGGTTACAAATGGAGCTGATA
GCGGGATAAAGTCTTATGTAAATACCATGAAAAAAAAAGGTATTAAAGTTATACTTACAGGTTGTGGTGCTGTAAGCAAA
GGCAAGGAGCTTTTAGATAAAAAACAAGTTTTTGGAGTGCTTGGAGCTTCAAATAAAGATAAAATTAATGAATTTTTAGG
AGCAAAGACAAGTTTTTATGAACTTGGAAATTTAAATTTTATTGATAAAGATATAGTTTGTGAGTATGAAAATCATACTA
AAGCTTTTGTGAAAATTCAAGAAGGTTGTGATTTTGCTTGTTCTTATTGTATTATCCCTAGCGTGCGGGGAAAATCAAGA
AGCGTGGATGAAAAAGCTCTTTTAAAACAGGTTGAAATTTTAGGAGCTAATGGCTATAGTGAAATTGTTTTAACAGGGAC
TAATATAGGTTCATATGGGCTTAAAAATGGCACAACTCTAGGCAAGCTTTTGCAAAAAATGGGACAAATTTCAGGTATAA
AACGCATAAGGTTAGGTAGTTTAGAACCCGCACAGCTTGATGAAAGTTTTTTAGAAATTTTAGATGAAACTTGGCTTGAA
AGGCATTTACATATTGCTTTGCAACATACAAGTGAAAAAATGCTTCGTATAATGAGAAGAAGATCGCATACGGATAATGA
TTTAAAGCTTTTTAATACTATAGCAAGCAAAGGATATGCTTTGGGGACGGATTTTATAGTAGCTCATCCAGGTGAGAGTG
AAGAGCTATGGCAAGAAGCTTTGAAAAAATTTAAAGAGTTTCCGCTCACTCATATTCATGCTTTTATTTTTAGTCCTAGA
AATAACACGCATTCTGCCACCATGAAAGATGTGATAAATGGAACTTTAGCTAAAGAAAGACTAAACACTCTAAAATCCAT
AGTGGAAAAAAATAATTATGAATTTAGGAAAAAAAATCAAGTTTCACTTGAAGTTTTGGTAGAAAATCAAAAAGATGGTT
TTTTTGAGGGTTATGATCAGTTTTTTAACAAGGTCAAAATTAAAAGCGATAAAGATATAGCTAAAGAATGGATCGTTATA
TCTGAATGTGAAGTGCAAGAGAAGTCTAACTTTGCAAATTTAAAAGGCTAG

Upstream 100 bases:

>100_bases
AAATCGCTTATCCATCGCAAAATTTATATTTAGGAAATTTAAACCAAAATCATTTTGAACAACATCATGAAAATACGCAT
TTTCATGCAAGGAATAAAGA

Downstream 100 bases:

>100_bases
ATAATGAAAAATAAAAAGATAATTTTAGCATCTTTTATGGTTTTATGTATGCTTTTGGGAATTTTATATTTTAAAAATGA
ACCTAAATATATAGATGAAA

Product: MiaB-like tRNA modifying enzyme

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MKEKVFFKTFGCRTNIYDTELLKSYVKDYEIINDENKAQIIVVNSCTVTNGADSGIKSYVNTMKKKGIKVILTGCGAVSK
GKELLDKKQVFGVLGASNKDKINEFLGAKTSFYELGNLNFIDKDIVCEYENHTKAFVKIQEGCDFACSYCIIPSVRGKSR
SVDEKALLKQVEILGANGYSEIVLTGTNIGSYGLKNGTTLGKLLQKMGQISGIKRIRLGSLEPAQLDESFLEILDETWLE
RHLHIALQHTSEKMLRIMRRRSHTDNDLKLFNTIASKGYALGTDFIVAHPGESEELWQEALKKFKEFPLTHIHAFIFSPR
NNTHSATMKDVINGTLAKERLNTLKSIVEKNNYEFRKKNQVSLEVLVENQKDGFFEGYDQFFNKVKIKSDKDIAKEWIVI
SECEVQEKSNFANLKG

Sequences:

>Translated_416_residues
MKEKVFFKTFGCRTNIYDTELLKSYVKDYEIINDENKAQIIVVNSCTVTNGADSGIKSYVNTMKKKGIKVILTGCGAVSK
GKELLDKKQVFGVLGASNKDKINEFLGAKTSFYELGNLNFIDKDIVCEYENHTKAFVKIQEGCDFACSYCIIPSVRGKSR
SVDEKALLKQVEILGANGYSEIVLTGTNIGSYGLKNGTTLGKLLQKMGQISGIKRIRLGSLEPAQLDESFLEILDETWLE
RHLHIALQHTSEKMLRIMRRRSHTDNDLKLFNTIASKGYALGTDFIVAHPGESEELWQEALKKFKEFPLTHIHAFIFSPR
NNTHSATMKDVINGTLAKERLNTLKSIVEKNNYEFRKKNQVSLEVLVENQKDGFFEGYDQFFNKVKIKSDKDIAKEWIVI
SECEVQEKSNFANLKG
>Mature_416_residues
MKEKVFFKTFGCRTNIYDTELLKSYVKDYEIINDENKAQIIVVNSCTVTNGADSGIKSYVNTMKKKGIKVILTGCGAVSK
GKELLDKKQVFGVLGASNKDKINEFLGAKTSFYELGNLNFIDKDIVCEYENHTKAFVKIQEGCDFACSYCIIPSVRGKSR
SVDEKALLKQVEILGANGYSEIVLTGTNIGSYGLKNGTTLGKLLQKMGQISGIKRIRLGSLEPAQLDESFLEILDETWLE
RHLHIALQHTSEKMLRIMRRRSHTDNDLKLFNTIASKGYALGTDFIVAHPGESEELWQEALKKFKEFPLTHIHAFIFSPR
NNTHSATMKDVINGTLAKERLNTLKSIVEKNNYEFRKKNQVSLEVLVENQKDGFFEGYDQFFNKVKIKSDKDIAKEWIVI
SECEVQEKSNFANLKG

Specific function: Unknown

COG id: COG0621

COG function: function code J; 2-methylthioadenine synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MTTase N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI28872784, Length=409, Percent_Identity=24.6943765281174, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI28872782, Length=409, Percent_Identity=24.6943765281174, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI93277076, Length=408, Percent_Identity=25.4901960784314, Blast_Score=123, Evalue=4e-28,
Organism=Escherichia coli, GI1786882, Length=392, Percent_Identity=26.0204081632653, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1787057, Length=387, Percent_Identity=26.0981912144703, Blast_Score=119, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17553146, Length=384, Percent_Identity=23.9583333333333, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI71996771, Length=291, Percent_Identity=25.7731958762887, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI21356207, Length=403, Percent_Identity=26.302729528536, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI19922432, Length=374, Percent_Identity=25.1336898395722, Blast_Score=102, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR020612
- InterPro:   IPR013848
- InterPro:   IPR006467
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM; PF00919 UPF0004 [H]

EC number: NA

Molecular weight: Translated: 47049; Mature: 47049

Theoretical pI: Translated: 8.81; Mature: 8.81

Prosite motif: PS01278 UPF0004

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEKVFFKTFGCRTNIYDTELLKSYVKDYEIINDENKAQIIVVNSCTVTNGADSGIKSYV
CCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCCCHHHHHHH
NTMKKKGIKVILTGCGAVSKGKELLDKKQVFGVLGASNKDKINEFLGAKTSFYELGNLNF
HHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEECCCCCE
IDKDIVCEYENHTKAFVKIQEGCDFACSYCIIPSVRGKSRSVDEKALLKQVEILGANGYS
ECCCCEEEECCCCEEEEEEECCCCCEEHEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCC
EIVLTGTNIGSYGLKNGTTLGKLLQKMGQISGIKRIRLGSLEPAQLDESFLEILDETWLE
EEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHH
RHLHIALQHTSEKMLRIMRRRSHTDNDLKLFNTIASKGYALGTDFIVAHPGESEELWQEA
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEECCCEEEECCCCCHHHHHHH
LKKFKEFPLTHIHAFIFSPRNNTHSATMKDVINGTLAKERLNTLKSIVEKNNYEFRKKNQ
HHHHHHCCHHEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
VSLEVLVENQKDGFFEGYDQFFNKVKIKSDKDIAKEWIVISECEVQEKSNFANLKG
CEEEEEEECCCCCCHHHHHHHHHHEECCCCHHHHHHCEEEECCCCHHCCCCCCCCC
>Mature Secondary Structure
MKEKVFFKTFGCRTNIYDTELLKSYVKDYEIINDENKAQIIVVNSCTVTNGADSGIKSYV
CCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCCCHHHHHHH
NTMKKKGIKVILTGCGAVSKGKELLDKKQVFGVLGASNKDKINEFLGAKTSFYELGNLNF
HHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEECCCCCE
IDKDIVCEYENHTKAFVKIQEGCDFACSYCIIPSVRGKSRSVDEKALLKQVEILGANGYS
ECCCCEEEECCCCEEEEEEECCCCCEEHEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCC
EIVLTGTNIGSYGLKNGTTLGKLLQKMGQISGIKRIRLGSLEPAQLDESFLEILDETWLE
EEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHH
RHLHIALQHTSEKMLRIMRRRSHTDNDLKLFNTIASKGYALGTDFIVAHPGESEELWQEA
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEECCCEEEECCCCCHHHHHHH
LKKFKEFPLTHIHAFIFSPRNNTHSATMKDVINGTLAKERLNTLKSIVEKNNYEFRKKNQ
HHHHHHCCHHEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
VSLEVLVENQKDGFFEGYDQFFNKVKIKSDKDIAKEWIVISECEVQEKSNFANLKG
CEEEEEEECCCCCCHHHHHHHHHHEECCCCHHHHHHCEEEECCCCHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]