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The map label for this gene is hsdM [C]

Identifier: 153951579

GI number: 153951579

Start: 625104

End: 627167

Strand: Direct

Name: hsdM [C]

Synonym: JJD26997_0689

Alternate gene names: 153951579

Gene position: 625104-627167 (Clockwise)

Preceding gene: 153952252

Following gene: 153951578

Centisome position: 33.88

GC content: 30.67

Gene sequence:

>2064_bases
ATGATTGAGGAAATTTTAAAAGATAGTGATTACAAGCTAGATCTATTTAGTAAAAAAGCTATTGCTGAATTAGAAACTAA
AATTATAGTTAAAACAAATAAAAATAACCAAATTATATACTATGCTAATTGCCTTGTCCGCGACAAAGAAATTAAACTTA
CACCAGAAGAAATTGTGCGTCAGCTTTATATCGATAAGCTTTTAAATGAATATAACTATCCTAAAGATATGATAAAAATT
GAATTCGGCGTGCATTTTGGACGCGAAGTAAAAAGAGCTGATATTGTGATAATGGATAAAATCCAAATCACAACCCCATA
CATCATTATAGAAGTAAAAAAACCAAAGTTGAAAGATGGCAAAGAACAATTAAAAAGTTATTGTAATGCTACAGGTGCAA
CTATGGCTGTGTGGTGTAATGGTAAAGAAATTAGCTATTATCATAGAAAAGATCCAAATTATTTTGAATCTATTCCAAAT
ATTCCTGCATCAAACCAGACATTACCAGATCTGTTGAAAGTAAAATTTACCTTTGATGATTTGATTAAAGAAGATATTTT
AAAAAATCAAAAGCGAAGTTTAAAGAATTTAGTTACAGAAATGGAAGATGAGGTGTTGGCAAATGCTGGAGTTGATGTAT
TTGAAGAATGTTTTAAGCTTATATTTATAAAACTTTTTGATGAGCTAGAGGGTGCAAGAGATAGAACAAAGAGCTTAGAA
TTTAGAAATTATGGAGAGTCTGATTCTGAACTTAAGCAAAAAATAGAAAAACTCTTTGATAAAGCAAAGAAAAAATGGGA
AGGTGTATTTAATAATGATGAGAAAATTAAACTTTCTCCTTCGCACCTAAGTGTATGTGTATCATCATTGCAAAATGTAA
AGTTATTTAACTCAAATTTAGAAGTGATTGATGATGCTTTTGAATATCTAGTGAATAAATCCTCAAAAGGTGAAAAAGGG
CAATATTTTACTCCGCGTTATGTAATAGATATGTGTGTAAAAATGCTAAATCCCAAAAAAGATGAAAGTATGATAGATAC
TGCAAGTGGAAGTTGTGGATTTCCGATACATACTTGTTTTTATGTGTGGCGTTCAATTTATAAAGAAAGAAGCATAGAAG
CAAGTCATCTCTTTACAGCCCAAGAAAAGATTCCTGAGTGTCAAGATTATGTAAAAGAAAAAGTGTTTGGTATAGATTTT
GATGAAAAAAGCGTGCGCGTATCAAAAATGCTTAATCTAATTGCAGGTGATGGGCATACCAATGTTTTGTATTTAAATTC
CATTGACTTTGATAGATGGGATGAATGGGTAAAAGATGATGAAGATTGGCAAGATGTGTATTTTGAAGGTTTTAAACGCT
TAAAAAATTTAAGAGCGACTAAAAATCAAAATAGGGATTTTAATTTTGATATTTTAATGGCAAATCCACCTTTTGCAGGA
GATATAAAAGAAAGTAGAATTTTAGCTAGATATGAGTTGGGCAAAAAGGAAAATGGCAAACCTCAAAGTAAAGTAGGAAG
AGATATTTTATTTATCGAACGAAATTTAGATATGTTGCGTCCTGGTGGCAGAATGGCTATTGTATTGCCACAAGGGCGTT
TTAATAATTCAAGCGATAAATATATAAGAGAATTTATCGCACAAAAAGCTAGAATCTTGGCAGTTGTAGGACTTCATGGA
AATGTCTTTAAACCACACACGGGGACAAAAACAAGTGTTTTATTTTTACAAAAATGGGATGATAAATTATGTCCAAAGTG
TGAGGATTATAATATCTTCTTTGCTACGATGAGTGAGCCTAGCAAAGATAATTCAGGCGAAAAGATTTATTACCCACTTT
TAGATTCTCATGATCATTTAGTTGTAAAACATGATTTGTTTCATCCACATTTAGAAGGCGATGAACCCATAAAACAAAAA
AATGAAAACCAAGAAGATTTTGATAAAAGAATGCAAGAATATAGGCTAAATATGGAAAAATACAAAGACTTGCAAAAAGA
TGGCATAGCTGAAGCTTTTATTGAATTTGCAAAGAGTGAAAATTTGAGTTTTTGGAAAGAATAA

Upstream 100 bases:

>100_bases
TGATAGAATTCACGCTATTGATGAAAGAGTAAGCATAGAAGAATTTGAAAAACTTTGCCTTGTTTTTAAAGACTTGATAG
AAAATTTTTAAAGGTTTAGA

Downstream 100 bases:

>100_bases
GCGAATGGATAATATGAAAGAATTTAAAATTTTTTGCGATGAAAGCAATCATTTATCCTACAAAGATAATCCAACTTTGT
GTTCAAAGGTTATGGTATTA

Product: DNA methylase-type I restriction-modification system

Products: S-Adenosyl-L-Homocysteine; DNA 6-Methylaminopurine. [C]

Alternate protein names: Type I Restriction- System M Subunit; Type I Restriction- System Methyltransferase Subunit; Type I Restriction M Protein; Type I Restriction System M Subunit; N-6 DNA Methylase Family; DNA Methylase-Type I Restriction- System; Type I Restriction- System; Type I Site-Specific Deoxyribonuclease; Type I Restriction EcoEI M Protein; Type I Restriction System N-6 DNA Methylase; NAD-Dependent DNA Ligase LigA; DNA-Methyltransferase Type I Restriction- Subunit M; Type II Restriction-; Type I Restriction- System M Protein; Restriction System DNA Specificity Subunit; N-6 DNA Methylase Family Protein; Site Specific DNA-Methyltransferase; Type I Restriction Methylase Subunit; Site-Specific DNA-Methyltransferase Subunit M; Restriction- Protein; Type I Restriction- System Modification Subunit; Restriction Endonuclease N6_Mtase Domain Protein; Type I Restriction/ System N-6 DNA Methyltransferase; Type III Restriction Protein Res Subunit; Type I Restriction- System M Subunit Protein; Restriction System Methylase; Restriction System DNA Specificity Domain Protein; Type I Restriction- System M-Subunit-Like Protein; XmnI Methyltransferase

Number of amino acids: Translated: 687; Mature: 687

Protein sequence:

>687_residues
MIEEILKDSDYKLDLFSKKAIAELETKIIVKTNKNNQIIYYANCLVRDKEIKLTPEEIVRQLYIDKLLNEYNYPKDMIKI
EFGVHFGREVKRADIVIMDKIQITTPYIIIEVKKPKLKDGKEQLKSYCNATGATMAVWCNGKEISYYHRKDPNYFESIPN
IPASNQTLPDLLKVKFTFDDLIKEDILKNQKRSLKNLVTEMEDEVLANAGVDVFEECFKLIFIKLFDELEGARDRTKSLE
FRNYGESDSELKQKIEKLFDKAKKKWEGVFNNDEKIKLSPSHLSVCVSSLQNVKLFNSNLEVIDDAFEYLVNKSSKGEKG
QYFTPRYVIDMCVKMLNPKKDESMIDTASGSCGFPIHTCFYVWRSIYKERSIEASHLFTAQEKIPECQDYVKEKVFGIDF
DEKSVRVSKMLNLIAGDGHTNVLYLNSIDFDRWDEWVKDDEDWQDVYFEGFKRLKNLRATKNQNRDFNFDILMANPPFAG
DIKESRILARYELGKKENGKPQSKVGRDILFIERNLDMLRPGGRMAIVLPQGRFNNSSDKYIREFIAQKARILAVVGLHG
NVFKPHTGTKTSVLFLQKWDDKLCPKCEDYNIFFATMSEPSKDNSGEKIYYPLLDSHDHLVVKHDLFHPHLEGDEPIKQK
NENQEDFDKRMQEYRLNMEKYKDLQKDGIAEAFIEFAKSENLSFWKE

Sequences:

>Translated_687_residues
MIEEILKDSDYKLDLFSKKAIAELETKIIVKTNKNNQIIYYANCLVRDKEIKLTPEEIVRQLYIDKLLNEYNYPKDMIKI
EFGVHFGREVKRADIVIMDKIQITTPYIIIEVKKPKLKDGKEQLKSYCNATGATMAVWCNGKEISYYHRKDPNYFESIPN
IPASNQTLPDLLKVKFTFDDLIKEDILKNQKRSLKNLVTEMEDEVLANAGVDVFEECFKLIFIKLFDELEGARDRTKSLE
FRNYGESDSELKQKIEKLFDKAKKKWEGVFNNDEKIKLSPSHLSVCVSSLQNVKLFNSNLEVIDDAFEYLVNKSSKGEKG
QYFTPRYVIDMCVKMLNPKKDESMIDTASGSCGFPIHTCFYVWRSIYKERSIEASHLFTAQEKIPECQDYVKEKVFGIDF
DEKSVRVSKMLNLIAGDGHTNVLYLNSIDFDRWDEWVKDDEDWQDVYFEGFKRLKNLRATKNQNRDFNFDILMANPPFAG
DIKESRILARYELGKKENGKPQSKVGRDILFIERNLDMLRPGGRMAIVLPQGRFNNSSDKYIREFIAQKARILAVVGLHG
NVFKPHTGTKTSVLFLQKWDDKLCPKCEDYNIFFATMSEPSKDNSGEKIYYPLLDSHDHLVVKHDLFHPHLEGDEPIKQK
NENQEDFDKRMQEYRLNMEKYKDLQKDGIAEAFIEFAKSENLSFWKE
>Mature_687_residues
MIEEILKDSDYKLDLFSKKAIAELETKIIVKTNKNNQIIYYANCLVRDKEIKLTPEEIVRQLYIDKLLNEYNYPKDMIKI
EFGVHFGREVKRADIVIMDKIQITTPYIIIEVKKPKLKDGKEQLKSYCNATGATMAVWCNGKEISYYHRKDPNYFESIPN
IPASNQTLPDLLKVKFTFDDLIKEDILKNQKRSLKNLVTEMEDEVLANAGVDVFEECFKLIFIKLFDELEGARDRTKSLE
FRNYGESDSELKQKIEKLFDKAKKKWEGVFNNDEKIKLSPSHLSVCVSSLQNVKLFNSNLEVIDDAFEYLVNKSSKGEKG
QYFTPRYVIDMCVKMLNPKKDESMIDTASGSCGFPIHTCFYVWRSIYKERSIEASHLFTAQEKIPECQDYVKEKVFGIDF
DEKSVRVSKMLNLIAGDGHTNVLYLNSIDFDRWDEWVKDDEDWQDVYFEGFKRLKNLRATKNQNRDFNFDILMANPPFAG
DIKESRILARYELGKKENGKPQSKVGRDILFIERNLDMLRPGGRMAIVLPQGRFNNSSDKYIREFIAQKARILAVVGLHG
NVFKPHTGTKTSVLFLQKWDDKLCPKCEDYNIFFATMSEPSKDNSGEKIYYPLLDSHDHLVVKHDLFHPHLEGDEPIKQK
NENQEDFDKRMQEYRLNMEKYKDLQKDGIAEAFIEFAKSENLSFWKE

Specific function: The M And S Subunits Together Form A Methyltransferase (Mtase) That Methylates Two Adenine Residues In Complementary Strands Of A Bipartite DNA Recognition Sequence. In The Presence Of The R Subunit The Complex Can Also Act As An Endonuclease, Binding To

COG id: COG0286

COG function: function code V; Type I restriction-modification system methyltransferase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.1.1.72 [C]

Molecular weight: Translated: 80248; Mature: 80248

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEEILKDSDYKLDLFSKKAIAELETKIIVKTNKNNQIIYYANCLVRDKEIKLTPEEIVR
CCHHHHCCCCCEEEHHHHHHHHHCCEEEEEEECCCCEEEEEEEEEEECCCEEECHHHHHH
QLYIDKLLNEYNYPKDMIKIEFGVHFGREVKRADIVIMDKIQITTPYIIIEVKKPKLKDG
HHHHHHHHHHCCCCHHHEEEEECCCCCCCCCCCCEEEEEEEEEECCEEEEEECCCCCCCH
KEQLKSYCNATGATMAVWCNGKEISYYHRKDPNYFESIPNIPASNQTLPDLLKVKFTFDD
HHHHHHHHCCCCCEEEEEECCCEEEEEECCCCCHHHHCCCCCCCCCCCCHHHEEEECHHH
LIKEDILKNQKRSLKNLVTEMEDEVLANAGVDVFEECFKLIFIKLFDELEGARDRTKSLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCHHHHHHCCC
FRNYGESDSELKQKIEKLFDKAKKKWEGVFNNDEKIKLSPSHLSVCVSSLQNVKLFNSNL
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECHHHHHHHHHHHHCCEEECCCH
EVIDDAFEYLVNKSSKGEKGQYFTPRYVIDMCVKMLNPKKDESMIDTASGSCGFPIHTCF
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCHHHHHH
YVWRSIYKERSIEASHLFTAQEKIPECQDYVKEKVFGIDFDEKSVRVSKMLNLIAGDGHT
HHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCC
NVLYLNSIDFDRWDEWVKDDEDWQDVYFEGFKRLKNLRATKNQNRDFNFDILMANPPFAG
CEEEEECCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCC
DIKESRILARYELGKKENGKPQSKVGRDILFIERNLDMLRPGGRMAIVLPQGRFNNSSDK
CCHHHHHHHHHHCCCCCCCCCHHHHCCEEEEEECCCHHCCCCCCEEEEECCCCCCCCHHH
YIREFIAQKARILAVVGLHGNVFKPHTGTKTSVLFLQKWDDKLCPKCEDYNIFFATMSEP
HHHHHHHHHCEEEEEEECCCCEECCCCCCCEEEEEEEECCCCCCCCCCCCEEEEEECCCC
SKDNSGEKIYYPLLDSHDHLVVKHDLFHPHLEGDEPIKQKNENQEDFDKRMQEYRLNMEK
CCCCCCCEEEEEECCCCCCEEEEECCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHCCHHH
YKDLQKDGIAEAFIEFAKSENLSFWKE
HHHHHHCCHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MIEEILKDSDYKLDLFSKKAIAELETKIIVKTNKNNQIIYYANCLVRDKEIKLTPEEIVR
CCHHHHCCCCCEEEHHHHHHHHHCCEEEEEEECCCCEEEEEEEEEEECCCEEECHHHHHH
QLYIDKLLNEYNYPKDMIKIEFGVHFGREVKRADIVIMDKIQITTPYIIIEVKKPKLKDG
HHHHHHHHHHCCCCHHHEEEEECCCCCCCCCCCCEEEEEEEEEECCEEEEEECCCCCCCH
KEQLKSYCNATGATMAVWCNGKEISYYHRKDPNYFESIPNIPASNQTLPDLLKVKFTFDD
HHHHHHHHCCCCCEEEEEECCCEEEEEECCCCCHHHHCCCCCCCCCCCCHHHEEEECHHH
LIKEDILKNQKRSLKNLVTEMEDEVLANAGVDVFEECFKLIFIKLFDELEGARDRTKSLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCHHHHHHCCC
FRNYGESDSELKQKIEKLFDKAKKKWEGVFNNDEKIKLSPSHLSVCVSSLQNVKLFNSNL
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECHHHHHHHHHHHHCCEEECCCH
EVIDDAFEYLVNKSSKGEKGQYFTPRYVIDMCVKMLNPKKDESMIDTASGSCGFPIHTCF
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCHHHHHH
YVWRSIYKERSIEASHLFTAQEKIPECQDYVKEKVFGIDFDEKSVRVSKMLNLIAGDGHT
HHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCC
NVLYLNSIDFDRWDEWVKDDEDWQDVYFEGFKRLKNLRATKNQNRDFNFDILMANPPFAG
CEEEEECCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCC
DIKESRILARYELGKKENGKPQSKVGRDILFIERNLDMLRPGGRMAIVLPQGRFNNSSDK
CCHHHHHHHHHHCCCCCCCCCHHHHCCEEEEEECCCHHCCCCCCEEEEECCCCCCCCHHH
YIREFIAQKARILAVVGLHGNVFKPHTGTKTSVLFLQKWDDKLCPKCEDYNIFFATMSEP
HHHHHHHHHCEEEEEEECCCCEECCCCCCCEEEEEEEECCCCCCCCCCCCEEEEEECCCC
SKDNSGEKIYYPLLDSHDHLVVKHDLFHPHLEGDEPIKQKNENQEDFDKRMQEYRLNMEK
CCCCCCCEEEEEECCCCCCEEEEECCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHCCHHH
YKDLQKDGIAEAFIEFAKSENLSFWKE
HHHHHHCCHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; DNA Adenine; DNA [C]

Specific reaction: S-Adenosyl-L-Methionine + DNA Adenine = S-Adenosyl-L-Homocysteine + DNA 6-Methylaminopurine. Protein + DNA = Protein-DNA [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA