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The map label for this gene is argF [H]

Identifier: 153951445

GI number: 153951445

Start: 718117

End: 719037

Strand: Direct

Name: argF [H]

Synonym: JJD26997_0795

Alternate gene names: 153951445

Gene position: 718117-719037 (Clockwise)

Preceding gene: 153951926

Following gene: 153952645

Centisome position: 38.92

GC content: 33.12

Gene sequence:

>921_bases
ATGAAACATTTTTTAACTTTAAGAGATTTTTCTAAGGAAGAAATTTTAAGCCTTGTAAATCATGCTAGTGAGCTTAAAAA
AGAGCCTAAAAAACTTTTACAAGATAAAACTTTGGCAATGATTTTTGAGAAAAACTCCACAAGAACAAGAATGGCTTTTG
AACTCGCAATAACAGAGCTTGGTGGGAAGGCTTTATTTTTAAGCAGTAATGATTTGCAACTTAGTCGAGGTGAACCTGTA
AAAGATACAGCTAGAGTGATAGGGGCGATGGTTGATTTTATAATGATGAGGGTAAATAAACACGAAAATTTACTAGAATT
TGCAAGATATTCTAAAGCTCCTGTGATCAATGCTTTAAGCGAACTTTATCATCCTACTCAGGTTTTAGGGGATTTGCTTA
CTATCAAAGAATGGAATAAAATACAAAATGGTATAGCAAAAGTTGCTTTTATCGGAGATAGTAATAATATGTGCAATTCT
TGGCTTATTGCGGCTGCGATTTTAGGCTTTGAATTTAGCATAGCTATACCAAAAAACTATGAAATTAACCCTGAAATTTG
GGATTTTGCTATGAAACAGGCTTTGATTTCAGGAGCTAAAATTTCTTTAAGTCATGATAAATTTAAAGCCTTAAAGGATA
AAGATGTAGTCATTACTGACACTTGGGTTTCCATGGGTGAAGAGAATGAAAAAGAACGTAAAATTAAAGAATTTGAAGAA
TTTATGATTGATGAAAAGGCCATGAGCGTTGCCAATGAAGATGCTATCTTGCTTCATTGTTTGCCTGCTTATAGGGGTTA
TGAAGTGAGTGAAGAAATTTTTGAAAAACATGCAGATGTGATTTTTGAAGAAGCAAGAAATCGCCTTTATGTGGTAAAAG
CCTTGCTTTGTTTTTTGGATAATCAGAGAGGAAGAAAATGA

Upstream 100 bases:

>100_bases
AAGTTTTGTATGAAACTATGATAGCTTTTAAAAGAGCAGGAGTAAAGCTTATCATCACTTATCATGCTAAAGAATTAGCT
AAAATGTTAAAAGGAGAAAA

Downstream 100 bases:

>100_bases
AAGAGCTAGAAAAGTATAGTACTTGCTTAAAGTGCATTGATGAATTTAGTCAAAATTTAGGAATCAAGAAAAAAGATAGA
ACGATTTTTAAAATGAAGCA

Product: ornithine carbamoyltransferase

Products: NA

Alternate protein names: OTCase [H]

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MKHFLTLRDFSKEEILSLVNHASELKKEPKKLLQDKTLAMIFEKNSTRTRMAFELAITELGGKALFLSSNDLQLSRGEPV
KDTARVIGAMVDFIMMRVNKHENLLEFARYSKAPVINALSELYHPTQVLGDLLTIKEWNKIQNGIAKVAFIGDSNNMCNS
WLIAAAILGFEFSIAIPKNYEINPEIWDFAMKQALISGAKISLSHDKFKALKDKDVVITDTWVSMGEENEKERKIKEFEE
FMIDEKAMSVANEDAILLHCLPAYRGYEVSEEIFEKHADVIFEEARNRLYVVKALLCFLDNQRGRK

Sequences:

>Translated_306_residues
MKHFLTLRDFSKEEILSLVNHASELKKEPKKLLQDKTLAMIFEKNSTRTRMAFELAITELGGKALFLSSNDLQLSRGEPV
KDTARVIGAMVDFIMMRVNKHENLLEFARYSKAPVINALSELYHPTQVLGDLLTIKEWNKIQNGIAKVAFIGDSNNMCNS
WLIAAAILGFEFSIAIPKNYEINPEIWDFAMKQALISGAKISLSHDKFKALKDKDVVITDTWVSMGEENEKERKIKEFEE
FMIDEKAMSVANEDAILLHCLPAYRGYEVSEEIFEKHADVIFEEARNRLYVVKALLCFLDNQRGRK
>Mature_306_residues
MKHFLTLRDFSKEEILSLVNHASELKKEPKKLLQDKTLAMIFEKNSTRTRMAFELAITELGGKALFLSSNDLQLSRGEPV
KDTARVIGAMVDFIMMRVNKHENLLEFARYSKAPVINALSELYHPTQVLGDLLTIKEWNKIQNGIAKVAFIGDSNNMCNS
WLIAAAILGFEFSIAIPKNYEINPEIWDFAMKQALISGAKISLSHDKFKALKDKDVVITDTWVSMGEENEKERKIKEFEE
FMIDEKAMSVANEDAILLHCLPAYRGYEVSEEIFEKHADVIFEEARNRLYVVKALLCFLDNQRGRK

Specific function: Arginine biosynthesis; sixth step. [C]

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family [H]

Homologues:

Organism=Homo sapiens, GI38788445, Length=304, Percent_Identity=38.1578947368421, Blast_Score=220, Evalue=1e-57,
Organism=Homo sapiens, GI18105007, Length=309, Percent_Identity=25.8899676375405, Blast_Score=96, Evalue=4e-20,
Organism=Escherichia coli, GI1790703, Length=323, Percent_Identity=36.5325077399381, Blast_Score=194, Evalue=8e-51,
Organism=Escherichia coli, GI1786469, Length=325, Percent_Identity=36.9230769230769, Blast_Score=192, Evalue=2e-50,
Organism=Escherichia coli, GI2367364, Length=317, Percent_Identity=28.0757097791798, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI48994908, Length=307, Percent_Identity=23.4527687296417, Blast_Score=78, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI193204318, Length=325, Percent_Identity=22.7692307692308, Blast_Score=76, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6322373, Length=324, Percent_Identity=39.1975308641975, Blast_Score=226, Evalue=4e-60,
Organism=Saccharomyces cerevisiae, GI6322331, Length=305, Percent_Identity=26.5573770491803, Blast_Score=93, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24642586, Length=315, Percent_Identity=26.031746031746, Blast_Score=96, Evalue=4e-20,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2066 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292 [H]

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N [H]

EC number: =2.1.3.3 [H]

Molecular weight: Translated: 35026; Mature: 35026

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: PS00097 CARBAMOYLTRANSFERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHFLTLRDFSKEEILSLVNHASELKKEPKKLLQDKTLAMIFEKNSTRTRMAFELAITEL
CCCEEEHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHC
GGKALFLSSNDLQLSRGEPVKDTARVIGAMVDFIMMRVNKHENLLEFARYSKAPVINALS
CCCEEEEECCCCEECCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHH
ELYHPTQVLGDLLTIKEWNKIQNGIAKVAFIGDSNNMCNSWLIAAAILGFEFSIAIPKNY
HHCCHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHHCEEEEECCCCC
EINPEIWDFAMKQALISGAKISLSHDKFKALKDKDVVITDTWVSMGEENEKERKIKEFEE
CCCHHHHHHHHHHHHHCCCEEEECHHHHHHHCCCCEEEEEHHHHCCCCCHHHHHHHHHHH
FMIDEKAMSVANEDAILLHCLPAYRGYEVSEEIFEKHADVIFEEARNRLYVVKALLCFLD
HHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NQRGRK
CCCCCC
>Mature Secondary Structure
MKHFLTLRDFSKEEILSLVNHASELKKEPKKLLQDKTLAMIFEKNSTRTRMAFELAITEL
CCCEEEHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHC
GGKALFLSSNDLQLSRGEPVKDTARVIGAMVDFIMMRVNKHENLLEFARYSKAPVINALS
CCCEEEEECCCCEECCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHH
ELYHPTQVLGDLLTIKEWNKIQNGIAKVAFIGDSNNMCNSWLIAAAILGFEFSIAIPKNY
HHCCHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHHCEEEEECCCCC
EINPEIWDFAMKQALISGAKISLSHDKFKALKDKDVVITDTWVSMGEENEKERKIKEFEE
CCCHHHHHHHHHHHHHCCCEEEECHHHHHHHCCCCEEEEEHHHHCCCCCHHHHHHHHHHH
FMIDEKAMSVANEDAILLHCLPAYRGYEVSEEIFEKHADVIFEEARNRLYVVKALLCFLD
HHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NQRGRK
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA