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The map label for this gene is prmA

Identifier: 153951432

GI number: 153951432

Start: 546275

End: 547123

Strand: Direct

Name: prmA

Synonym: JJD26997_0604

Alternate gene names: 153951432

Gene position: 546275-547123 (Clockwise)

Preceding gene: 153952086

Following gene: 153952359

Centisome position: 29.61

GC content: 28.15

Gene sequence:

>849_bases
ATGCAAAAAAAATATTACGAATTGTTCTTTATCGTAGAAGAGCAGTATAAAAATTTATTTCTTGGTTTTGCTTTTGATTT
AGGTATAGAAGCCATAGAAGAGAAAGATAATGGTATTTATATTAGATCCCATGAGAGTTTAGAAGAGCTTTCATGGGCAC
TTGAAATATTTGCTCAAAAACTTACAACTACTTTCAATTTAAACCATAAAATTATTTCTAATTTAAGTCTTGTAGAGAAA
GAAAACAAGGACTGGATACAAGAATATAAAAAAGGCATAAAACCTATTTTAGTGGATAATGTTTACATCCATACCACTTG
GCAAGAAGAAAAAAAGAATTGTATAAATATAAAGATTAATCCAGCCTTAGCCTTTGGCTCAGGACATCACGAAAGCACAC
ATTCTTGTGTAAAATTTTTGCAAAAATTTTCTAAAAGTAAATTAAGAGCCTTAGATCTTGGTTGTGGTAGTGGAATTTTG
GGTATTATTATGGCAAAGTTTGGCTGTAATGTTGAAATTTGTGATACTGATGAGTTGGCTATTGATAGTTCTTTGGAAAA
TGCAAGATTAAATGGTGTCGATTTTCACAAGGCTTGGTGTGGATCTATAGATAAAGCAAATGGTTTATATAATCTAATTG
TTGCAAATATCATTGCAGATGTGATTTTAATTTTAGAAAAAGATATTAAAAACCATTTAGAAGATAATGCTATACTTATT
TTGTCAGGAATTTTAGATAAATATTCAACAAGAATTAAAGAAAAATTTCAAGATTTAGAACTCATTGATGAAATGCAAAT
CAATGAGTGGTGTAGTTTTGTATATAAAAATAATAAAAAGGATAAGTAA

Upstream 100 bases:

>100_bases
CCTTTTACTCCACAAGTTTTAAAGGAAAAACTTGAAGATGTTTTAGGAACAGGAAGTGGAGAAGGTGCAGCTGAGTAAAG
GCTGATTTTTAAAATTTTAA

Downstream 100 bases:

>100_bases
TGAATAATAATACCCCGAATAATAAGGGTAATCCGCAGGGTAATAATTTTTTTAACAAAAATCCCATTTTTATTTTTGCG
ATTTTTGCAATTATAATGAT

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MQKKYYELFFIVEEQYKNLFLGFAFDLGIEAIEEKDNGIYIRSHESLEELSWALEIFAQKLTTTFNLNHKIISNLSLVEK
ENKDWIQEYKKGIKPILVDNVYIHTTWQEEKKNCINIKINPALAFGSGHHESTHSCVKFLQKFSKSKLRALDLGCGSGIL
GIIMAKFGCNVEICDTDELAIDSSLENARLNGVDFHKAWCGSIDKANGLYNLIVANIIADVILILEKDIKNHLEDNAILI
LSGILDKYSTRIKEKFQDLELIDEMQINEWCSFVYKNNKKDK

Sequences:

>Translated_282_residues
MQKKYYELFFIVEEQYKNLFLGFAFDLGIEAIEEKDNGIYIRSHESLEELSWALEIFAQKLTTTFNLNHKIISNLSLVEK
ENKDWIQEYKKGIKPILVDNVYIHTTWQEEKKNCINIKINPALAFGSGHHESTHSCVKFLQKFSKSKLRALDLGCGSGIL
GIIMAKFGCNVEICDTDELAIDSSLENARLNGVDFHKAWCGSIDKANGLYNLIVANIIADVILILEKDIKNHLEDNAILI
LSGILDKYSTRIKEKFQDLELIDEMQINEWCSFVYKNNKKDK
>Mature_282_residues
MQKKYYELFFIVEEQYKNLFLGFAFDLGIEAIEEKDNGIYIRSHESLEELSWALEIFAQKLTTTFNLNHKIISNLSLVEK
ENKDWIQEYKKGIKPILVDNVYIHTTWQEEKKNCINIKINPALAFGSGHHESTHSCVKFLQKFSKSKLRALDLGCGSGIL
GIIMAKFGCNVEICDTDELAIDSSLENARLNGVDFHKAWCGSIDKANGLYNLIVANIIADVILILEKDIKNHLEDNAILI
LSGILDKYSTRIKEKFQDLELIDEMQINEWCSFVYKNNKKDK

Specific function: Methylates ribosomal protein L11

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family

Homologues:

Organism=Escherichia coli, GI2367208, Length=143, Percent_Identity=33.5664335664336, Blast_Score=79, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRMA_CAMJD (A7H2P1)

Other databases:

- EMBL:   CP000768
- RefSeq:   YP_001397771.1
- ProteinModelPortal:   A7H2P1
- SMR:   A7H2P1
- STRING:   A7H2P1
- GeneID:   5389165
- GenomeReviews:   CP000768_GR
- KEGG:   cjd:JJD26997_0604
- eggNOG:   COG2264
- HOGENOM:   HBG584653
- OMA:   YIRSHES
- ProtClustDB:   PRK00517
- BioCyc:   CJEJ360109:JJD26997_0604-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00735
- InterPro:   IPR010456
- InterPro:   IPR004498

Pfam domain/function: PF06325 PrmA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 32406; Mature: 32406

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKKYYELFFIVEEQYKNLFLGFAFDLGIEAIEEKDNGIYIRSHESLEELSWALEIFAQK
CCCCEEEEEEEEEHHHHHHHHHHHHHHCHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHH
LTTTFNLNHKIISNLSLVEKENKDWIQEYKKGIKPILVDNVYIHTTWQEEKKNCINIKIN
HHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCEEEECCEEEEECCHHCCCCEEEEEEE
PALAFGSGHHESTHSCVKFLQKFSKSKLRALDLGCGSGILGIIMAKFGCNVEICDTDELA
EEEEECCCCCCCHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHCCCEEEECCCCHH
IDSSLENARLNGVDFHKAWCGSIDKANGLYNLIVANIIADVILILEKDIKNHLEDNAILI
HCCCCCCCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
LSGILDKYSTRIKEKFQDLELIDEMQINEWCSFVYKNNKKDK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MQKKYYELFFIVEEQYKNLFLGFAFDLGIEAIEEKDNGIYIRSHESLEELSWALEIFAQK
CCCCEEEEEEEEEHHHHHHHHHHHHHHCHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHH
LTTTFNLNHKIISNLSLVEKENKDWIQEYKKGIKPILVDNVYIHTTWQEEKKNCINIKIN
HHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCEEEECCEEEEECCHHCCCCEEEEEEE
PALAFGSGHHESTHSCVKFLQKFSKSKLRALDLGCGSGILGIIMAKFGCNVEICDTDELA
EEEEECCCCCCCHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHCCCEEEECCCCHH
IDSSLENARLNGVDFHKAWCGSIDKANGLYNLIVANIIADVILILEKDIKNHLEDNAILI
HCCCCCCCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
LSGILDKYSTRIKEKFQDLELIDEMQINEWCSFVYKNNKKDK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA