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The map label for this gene is serB [C]

Identifier: 153951431

GI number: 153951431

Start: 1490527

End: 1491150

Strand: Direct

Name: serB [C]

Synonym: JJD26997_1689

Alternate gene names: 153951431

Gene position: 1490527-1491150 (Clockwise)

Preceding gene: 153952625

Following gene: 153951122

Centisome position: 80.78

GC content: 31.41

Gene sequence:

>624_bases
ATGATTAAACTTTGTGTTTTTGACTTTGATGCTACTTTAATGGATGGTGAAACCATCGATATTTTAGCTACAGCACATGG
AAAGGGTAATCAAATAAGCGAAATTACCCGTTATGCCATGGCTGGAGAGCTTGATTTTTTCGAAAGTCTTCAAAAACGAG
TAAGCTTTTTAAAAGGTATGTCTTATAAAAAAGTTTTAGAATTAGGTAGCACACTTCCACTAATGCATGGAGCACATGAA
CTTATCCAATATTTAAAATCTAAAAACATACAAATTGTTATTTTTAGCGGTGGTTTTCATGAAGGTATAGATCCTGCTAT
GCAAAAACTTGGAATTAACCTTGGTTTTGCAAATTATCTGCATCATAAAAATGACATTTTAACAGGGCTAATTGGCGGGG
AAATAATGTTTTCAAATTCAAAAGGCTTAATGCTACAACGATTAAAAAGCTTTTTAAATTTGAAAACAGATGAAGTGATG
TGTGTTGGCGATGGGGCAAATGATTTGGCAATGTTTAATGAAAGTGGATTAAAGATTGCATTTTGTGCTAAAGAAATTTT
ACGTTCTCAAGCTGATATTTGCATAGATATAAAAGACTTAAAAGAAATAATAAAGGTAATATAA

Upstream 100 bases:

>100_bases
CTTTAGTTAAAGACAAAGGTATGATTTATGGTATAGGAAAAAGAGATGAAAATATCTTAACTATACTCAAAGTAGAAGCT
TTACTTAAGCGCGAATTTTA

Downstream 100 bases:

>100_bases
TGAAAAATTTTTCTCTTTGGTGTGATTTTATAGAAAATAGTTTTTTAGATAATGAATTTTTAAATTTATTATCACATGAA
ATTAATGGAGCTACTTCAAA

Product: phosphoserine phosphatase SerB

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MIKLCVFDFDATLMDGETIDILATAHGKGNQISEITRYAMAGELDFFESLQKRVSFLKGMSYKKVLELGSTLPLMHGAHE
LIQYLKSKNIQIVIFSGGFHEGIDPAMQKLGINLGFANYLHHKNDILTGLIGGEIMFSNSKGLMLQRLKSFLNLKTDEVM
CVGDGANDLAMFNESGLKIAFCAKEILRSQADICIDIKDLKEIIKVI

Sequences:

>Translated_207_residues
MIKLCVFDFDATLMDGETIDILATAHGKGNQISEITRYAMAGELDFFESLQKRVSFLKGMSYKKVLELGSTLPLMHGAHE
LIQYLKSKNIQIVIFSGGFHEGIDPAMQKLGINLGFANYLHHKNDILTGLIGGEIMFSNSKGLMLQRLKSFLNLKTDEVM
CVGDGANDLAMFNESGLKIAFCAKEILRSQADICIDIKDLKEIIKVI
>Mature_207_residues
MIKLCVFDFDATLMDGETIDILATAHGKGNQISEITRYAMAGELDFFESLQKRVSFLKGMSYKKVLELGSTLPLMHGAHE
LIQYLKSKNIQIVIFSGGFHEGIDPAMQKLGINLGFANYLHHKNDILTGLIGGEIMFSNSKGLMLQRLKSFLNLKTDEVM
CVGDGANDLAMFNESGLKIAFCAKEILRSQADICIDIKDLKEIIKVI

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serB family [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=190, Percent_Identity=31.0526315789474, Blast_Score=72, Evalue=3e-13,
Organism=Escherichia coli, GI1790849, Length=197, Percent_Identity=35.5329949238579, Blast_Score=112, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6321647, Length=207, Percent_Identity=34.2995169082126, Blast_Score=105, Evalue=5e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 22966; Mature: 22966

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKLCVFDFDATLMDGETIDILATAHGKGNQISEITRYAMAGELDFFESLQKRVSFLKGM
CEEEEEEECCCEEECCCEEEEEEECCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCC
SYKKVLELGSTLPLMHGAHELIQYLKSKNIQIVIFSGGFHEGIDPAMQKLGINLGFANYL
CHHHHHHCCCCCCHHCCHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHCCCCCHHHHH
HHKNDILTGLIGGEIMFSNSKGLMLQRLKSFLNLKTDEVMCVGDGANDLAMFNESGLKIA
HCCHHHHEEEECCEEEEECCCCHHHHHHHHHHCCCCCCEEEEECCCCCCEEECCCCCEEH
FCAKEILRSQADICIDIKDLKEIIKVI
HHHHHHHHCCCCEEEEHHHHHHHHHHC
>Mature Secondary Structure
MIKLCVFDFDATLMDGETIDILATAHGKGNQISEITRYAMAGELDFFESLQKRVSFLKGM
CEEEEEEECCCEEECCCEEEEEEECCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCC
SYKKVLELGSTLPLMHGAHELIQYLKSKNIQIVIFSGGFHEGIDPAMQKLGINLGFANYL
CHHHHHHCCCCCCHHCCHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHCCCCCHHHHH
HHKNDILTGLIGGEIMFSNSKGLMLQRLKSFLNLKTDEVMCVGDGANDLAMFNESGLKIA
HCCHHHHEEEECCEEEEECCCCHHHHHHHHHHCCCCCCEEEEECCCCCCEEECCCCCEEH
FCAKEILRSQADICIDIKDLKEIIKVI
HHHHHHHHCCCCEEEEHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087; 11342136; 12051918 [H]