Click here to switch to the map view.

The map label for this gene is cpxA [H]

Identifier: 153951367

GI number: 153951367

Start: 448195

End: 449367

Strand: Direct

Name: cpxA [H]

Synonym: JJD26997_0499

Alternate gene names: 153951367

Gene position: 448195-449367 (Clockwise)

Preceding gene: 153952027

Following gene: 153951991

Centisome position: 24.29

GC content: 27.62

Gene sequence:

>1173_bases
TTGTGGCTTATAGAATATGATCAGCAAAATTATACTAGAGAATTAAATATCAAATATTCTTTGATAGCTAATGCAAGACT
TTTAAATTTTGCAGGAGTTATCAGTGAAAAAGAATTTGAAGAGCAGACAAAAAATTATAATAAAATGGATGAGATAACAG
AAGCAAAGCAGATCCGTAAAATTCTTTTTAGAGGTGATGTTTTAGCTAGGGTTGAGGTTAATAATGGCTTAATCGAGATT
ATTTCTTATAATAGACAGGTATATTTAAATATTATTTATGATGGAAAGGTTTATCTTTATAAGGATCAAGATTATCAAAC
CTATAGGTATTTTATTATCAAAGCTATAGCTGTAGCTGTGATTTGTATTCTTGTATTGCTTTATATTTATATATTTAAAA
AATTAAAACCACTTAAAAGACTTAAAAAACAAATTGATAAATTTGCCCAAGGAAAGCTTAATGATATAGAAGATGTAAGC
ACTGGGGTAGATGAAATTTCACAAGTAGGTGAAGCTTTTTATCAAGCCATTGTTCAAATTCGAAAGCTAAATCAATCTCG
TCAGTTTTTTTTAAGAAATATTATGCATGAACTCAAAACTCCCATTACTAAGGGGCTCTTAACTTTAGAAATGATAGAAG
ATAATAAATATAAAGAGCGCTTAAATGGGGTTTTTACTAGACTTGAAATTTTAATTAATGAATTTGCTGCTATTGAGCAA
ATTACTTCAGGGGCTGCTTTTATAAATAGAAAAAAATACAATATTTTAGATGTTTTAGATGAAGCCAAAGAAATTGCAAT
GCGAGATGATAGCAATATACGTATTTTTATGGAAGAAAGTTTTTTTGTGAATGTGGATTTTAAACTTTTTACTACGGCGA
TTAAAAATATGATAGATAATGGTATTAAACATTCTGAAGATGGGTTTGTGCAAATTGATATTATAGATGATTATATTTGT
TTTAAAAATCGTGGCCCTGAGCTTAACAATACTTTAGAATACTATACTCAAGCTTTTACTCAAGGATCAAAACAAAAATC
AAGTTTTGGATTAGGGCTTTACATTGTAAATACTATTTTAGAAACACACGGAATGAAGCTTGATTATTTATATGAAGATG
GGGTAAATTTGTTTTTTTTTAGAAATTTAAAAAGCCTTATTGTTAAGGAGTAA

Upstream 100 bases:

>100_bases
GTGGAATAGGTTATAAGCTTACTCAATGAATAAATCTTCGATTTTTTATACTATAACTTTTATTTTTATTTTTGCTGGGG
TTAGTGTTATACTTGGCTTT

Downstream 100 bases:

>100_bases
ATTAATTTTTTTTTGCATAAAAAATGCATTTTTGTGCAAAAACCCTTGACAAAGTTTTTTAATTTCAATATAATCATATT
TTACTTTTAAATATTCCGGA

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MWLIEYDQQNYTRELNIKYSLIANARLLNFAGVISEKEFEEQTKNYNKMDEITEAKQIRKILFRGDVLARVEVNNGLIEI
ISYNRQVYLNIIYDGKVYLYKDQDYQTYRYFIIKAIAVAVICILVLLYIYIFKKLKPLKRLKKQIDKFAQGKLNDIEDVS
TGVDEISQVGEAFYQAIVQIRKLNQSRQFFLRNIMHELKTPITKGLLTLEMIEDNKYKERLNGVFTRLEILINEFAAIEQ
ITSGAAFINRKKYNILDVLDEAKEIAMRDDSNIRIFMEESFFVNVDFKLFTTAIKNMIDNGIKHSEDGFVQIDIIDDYIC
FKNRGPELNNTLEYYTQAFTQGSKQKSSFGLGLYIVNTILETHGMKLDYLYEDGVNLFFFRNLKSLIVKE

Sequences:

>Translated_390_residues
MWLIEYDQQNYTRELNIKYSLIANARLLNFAGVISEKEFEEQTKNYNKMDEITEAKQIRKILFRGDVLARVEVNNGLIEI
ISYNRQVYLNIIYDGKVYLYKDQDYQTYRYFIIKAIAVAVICILVLLYIYIFKKLKPLKRLKKQIDKFAQGKLNDIEDVS
TGVDEISQVGEAFYQAIVQIRKLNQSRQFFLRNIMHELKTPITKGLLTLEMIEDNKYKERLNGVFTRLEILINEFAAIEQ
ITSGAAFINRKKYNILDVLDEAKEIAMRDDSNIRIFMEESFFVNVDFKLFTTAIKNMIDNGIKHSEDGFVQIDIIDDYIC
FKNRGPELNNTLEYYTQAFTQGSKQKSSFGLGLYIVNTILETHGMKLDYLYEDGVNLFFFRNLKSLIVKE
>Mature_390_residues
MWLIEYDQQNYTRELNIKYSLIANARLLNFAGVISEKEFEEQTKNYNKMDEITEAKQIRKILFRGDVLARVEVNNGLIEI
ISYNRQVYLNIIYDGKVYLYKDQDYQTYRYFIIKAIAVAVICILVLLYIYIFKKLKPLKRLKKQIDKFAQGKLNDIEDVS
TGVDEISQVGEAFYQAIVQIRKLNQSRQFFLRNIMHELKTPITKGLLTLEMIEDNKYKERLNGVFTRLEILINEFAAIEQ
ITSGAAFINRKKYNILDVLDEAKEIAMRDDSNIRIFMEESFFVNVDFKLFTTAIKNMIDNGIKHSEDGFVQIDIIDDYIC
FKNRGPELNNTLEYYTQAFTQGSKQKSSFGLGLYIVNTILETHGMKLDYLYEDGVNLFFFRNLKSLIVKE

Specific function: This protein is involved in several diverse cellular processes, such as the functioning of acetohydroxyacid synthetase I, in the biosynthesis of isoleucine and valine, the TraJ protein activation activity for tra gene expression in F plasmid, and the synt

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790346, Length=247, Percent_Identity=26.7206477732794, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 45784; Mature: 45784

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWLIEYDQQNYTRELNIKYSLIANARLLNFAGVISEKEFEEQTKNYNKMDEITEAKQIRK
CEEEEECCCCCCEEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
ILFRGDVLARVEVNNGLIEIISYNRQVYLNIIYDGKVYLYKDQDYQTYRYFIIKAIAVAV
HHHCCCEEEEEEECCCEEEEEECCCEEEEEEEEECEEEEEECCCCHHHHHHHHHHHHHHH
ICILVLLYIYIFKKLKPLKRLKKQIDKFAQGKLNDIEDVSTGVDEISQVGEAFYQAIVQI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHH
RKLNQSRQFFLRNIMHELKTPITKGLLTLEMIEDNKYKERLNGVFTRLEILINEFAAIEQ
HHHCHHHHHHHHHHHHHHHCHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ITSGAAFINRKKYNILDVLDEAKEIAMRDDSNIRIFMEESFFVNVDFKLFTTAIKNMIDN
HHCCHHHHCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCEEEEEHHHHHHHHHHHHHHC
GIKHSEDGFVQIDIIDDYICFKNRGPELNNTLEYYTQAFTQGSKQKSSFGLGLYIVNTIL
CCCCCCCCEEEEEEECCCCEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
ETHGMKLDYLYEDGVNLFFFRNLKSLIVKE
HHCCCEEEEEEECCCCEEEHHHHHHHHCCC
>Mature Secondary Structure
MWLIEYDQQNYTRELNIKYSLIANARLLNFAGVISEKEFEEQTKNYNKMDEITEAKQIRK
CEEEEECCCCCCEEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
ILFRGDVLARVEVNNGLIEIISYNRQVYLNIIYDGKVYLYKDQDYQTYRYFIIKAIAVAV
HHHCCCEEEEEEECCCEEEEEECCCEEEEEEEEECEEEEEECCCCHHHHHHHHHHHHHHH
ICILVLLYIYIFKKLKPLKRLKKQIDKFAQGKLNDIEDVSTGVDEISQVGEAFYQAIVQI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHH
RKLNQSRQFFLRNIMHELKTPITKGLLTLEMIEDNKYKERLNGVFTRLEILINEFAAIEQ
HHHCHHHHHHHHHHHHHHHCHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ITSGAAFINRKKYNILDVLDEAKEIAMRDDSNIRIFMEESFFVNVDFKLFTTAIKNMIDN
HHCCHHHHCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCEEEEEHHHHHHHHHHHHHHC
GIKHSEDGFVQIDIIDDYICFKNRGPELNNTLEYYTQAFTQGSKQKSSFGLGLYIVNTIL
CCCCCCCCEEEEEEECCCCEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
ETHGMKLDYLYEDGVNLFFFRNLKSLIVKE
HHCCCEEEEEEECCCCEEEHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]