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The map label for this gene is sppA [C]

Identifier: 153951329

GI number: 153951329

Start: 85072

End: 85968

Strand: Direct

Name: sppA [C]

Synonym: JJD26997_0078

Alternate gene names: 153951329

Gene position: 85072-85968 (Clockwise)

Preceding gene: 153952082

Following gene: 153951159

Centisome position: 4.61

GC content: 33.11

Gene sequence:

>897_bases
ATGCAAAATTTAAAATCATTTTTTAAGGCTTTAGGATGCGGTATAAAATTTATCAATACTTATTTTAAAACCTTTGTTTT
ATTGTTGATTGTTATATGGATTTTGGTGCCTAGTGCAAATTCAAGCTCCAAGCTTGCAAATTTAGAACGCATTGATTTAA
AGGGTGAAATTTTTGATAGTTCTGCAGTTTTAGAAAAAATTATCAATGCTAAAAATGATAGCAATATCAAAGGAGTGCTT
TTTGTTATAGACTCTCCTGGTGGAGCTTTTGCTCCTAGTATGGAACTAGCTCTAGCTATAAAGGATTTAAAAATTAAAAA
GTCTGTGCTTGTTTATGCAAGCGGAACTATGGCAAGTGGAAGTTATTTAGCAGGAGTTGGAGCGAATAAAATTTTAGCCA
ATCCGGCAAGTTTTATAGGCTCTATTGGTGTGATTATGCAAGGAGCTGATTTAAGCGGATTGGCTAATAAACTCGGCATT
AAAGAACAAACTATTCAAGCGGGTGAATTTAAAAGTGCTGGAACTTTTGCAAGAGCTTGGAATGAGAATGAAAGAAATTT
TTTACAGGGTTTAATTGATCAAAGTTATGATCTTTTTACAGGTTTTGTTGCCAAGGAAAGAGTACTAGATCTTAACAAAA
AAGATCAGTGGGCAAATGCAAGAGTATTTTTAGCTGCCAAGGCTAAGGAACTTGGTCTTATAGATGAGCTTAGTAATTAT
GAAAATGCCAAAAAGGAGCTTGAAAAACTTGCTAATGTTTCAAATCCTATTTGGAAAGAAGAAGATAAGATCGATAAATT
TCTTAACCGCCTAAAAGGACAAGCATCAAGCTTGATAAGTAAAAGCTTAATCGAAATTGCTTATAAGACTAATAGCGGTT
TTATAAACGCTAGATAA

Upstream 100 bases:

>100_bases
TTAGTGTATTTGAGCTAGGAGAATGTGATAAAAAGCAAGCTCCTTTGCAGTTTATTTTAAATGCTAAGGAAGTAGATAAA
TTATTTATAAAAGGAAAAGA

Downstream 100 bases:

>100_bases
AATATATAAATATTTTTATTTAATTTTTGCAATATTTTTATGTAATAATTATTTATATCTTAGATAAGGAGTAGGATAAT
GAAAAAAATATTGTTTTTTT

Product: signal peptide peptidase SppA, 36K type

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MQNLKSFFKALGCGIKFINTYFKTFVLLLIVIWILVPSANSSSKLANLERIDLKGEIFDSSAVLEKIINAKNDSNIKGVL
FVIDSPGGAFAPSMELALAIKDLKIKKSVLVYASGTMASGSYLAGVGANKILANPASFIGSIGVIMQGADLSGLANKLGI
KEQTIQAGEFKSAGTFARAWNENERNFLQGLIDQSYDLFTGFVAKERVLDLNKKDQWANARVFLAAKAKELGLIDELSNY
ENAKKELEKLANVSNPIWKEEDKIDKFLNRLKGQASSLISKSLIEIAYKTNSGFINAR

Sequences:

>Translated_298_residues
MQNLKSFFKALGCGIKFINTYFKTFVLLLIVIWILVPSANSSSKLANLERIDLKGEIFDSSAVLEKIINAKNDSNIKGVL
FVIDSPGGAFAPSMELALAIKDLKIKKSVLVYASGTMASGSYLAGVGANKILANPASFIGSIGVIMQGADLSGLANKLGI
KEQTIQAGEFKSAGTFARAWNENERNFLQGLIDQSYDLFTGFVAKERVLDLNKKDQWANARVFLAAKAKELGLIDELSNY
ENAKKELEKLANVSNPIWKEEDKIDKFLNRLKGQASSLISKSLIEIAYKTNSGFINAR
>Mature_298_residues
MQNLKSFFKALGCGIKFINTYFKTFVLLLIVIWILVPSANSSSKLANLERIDLKGEIFDSSAVLEKIINAKNDSNIKGVL
FVIDSPGGAFAPSMELALAIKDLKIKKSVLVYASGTMASGSYLAGVGANKILANPASFIGSIGVIMQGADLSGLANKLGI
KEQTIQAGEFKSAGTFARAWNENERNFLQGLIDQSYDLFTGFVAKERVLDLNKKDQWANARVFLAAKAKELGLIDELSNY
ENAKKELEKLANVSNPIWKEEDKIDKFLNRLKGQASSLISKSLIEIAYKTNSGFINAR

Specific function: Digestion Of The Cleaved Signal Peptides. This Activity Is Necessary To Maintain Proper Secretion Of Mature Proteins Across The Membrane. [C]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S49 family [H]

Homologues:

Organism=Escherichia coli, GI1788064, Length=225, Percent_Identity=24.4444444444444, Blast_Score=73, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004635
- InterPro:   IPR002142 [H]

Pfam domain/function: PF01343 Peptidase_S49 [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 32556; Mature: 32556

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNLKSFFKALGCGIKFINTYFKTFVLLLIVIWILVPSANSSSKLANLERIDLKGEIFDS
CCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCHHEECCCCCCCCH
SAVLEKIINAKNDSNIKGVLFVIDSPGGAFAPSMELALAIKDLKIKKSVLVYASGTMASG
HHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHEECEEEEEECCCCCCC
SYLAGVGANKILANPASFIGSIGVIMQGADLSGLANKLGIKEQTIQAGEFKSAGTFARAW
CEEECCCCCHHHCCHHHHHHHHHHHEECCCHHHHHHHHCCCHHHHCCCCCCCCCHHHHHC
NENERNFLQGLIDQSYDLFTGFVAKERVLDLNKKDQWANARVFLAAKAKELGLIDELSNY
CCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECHHHHCHHHHHHHH
ENAKKELEKLANVSNPIWKEEDKIDKFLNRLKGQASSLISKSLIEIAYKTNSGFINAR
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHEECCCCEEECC
>Mature Secondary Structure
MQNLKSFFKALGCGIKFINTYFKTFVLLLIVIWILVPSANSSSKLANLERIDLKGEIFDS
CCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCHHEECCCCCCCCH
SAVLEKIINAKNDSNIKGVLFVIDSPGGAFAPSMELALAIKDLKIKKSVLVYASGTMASG
HHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHEECEEEEEECCCCCCC
SYLAGVGANKILANPASFIGSIGVIMQGADLSGLANKLGIKEQTIQAGEFKSAGTFARAW
CEEECCCCCHHHCCHHHHHHHHHHHEECCCHHHHHHHHCCCHHHHCCCCCCCCCHHHHHC
NENERNFLQGLIDQSYDLFTGFVAKERVLDLNKKDQWANARVFLAAKAKELGLIDELSNY
CCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECHHHHCHHHHHHHH
ENAKKELEKLANVSNPIWKEEDKIDKFLNRLKGQASSLISKSLIEIAYKTNSGFINAR
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHEECCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]