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The map label for this gene is gmhB [H]

Identifier: 153951278

GI number: 153951278

Start: 518877

End: 519434

Strand: Direct

Name: gmhB [H]

Synonym: JJD26997_0576

Alternate gene names: 153951278

Gene position: 518877-519434 (Clockwise)

Preceding gene: 153951059

Following gene: 153951617

Centisome position: 28.12

GC content: 25.63

Gene sequence:

>558_bases
ATGTTTATTTTCTTTTTAAAAAAGCTATATTATAATGTTTTTATGAAAACAAAAGCCTTATTTTTAGATAGAGACGGTGT
GATTAATATAGATAAAAAATATGTCTATAAAATAGAAGATTTTGAATTTTGTGATGGAATTTTTGAACTTTGTAGATATT
TTTTAGCTAGAAATTATTTGCTTTTTATAGCGACAAATCAATCAGGCATTGCAAGAGGATATTACAAGGAAAGTGATTTT
TTTAAGCTTTGTGATTATATGCTTAAAGAATTTGCCAAACAAGATATAAAAATTGATAAAATTTATTATTGTCCGCATTT
AGAAGGTTGCGAGTGTCGCAAACCTAAAGCAGGAATGCTTTTAAAAGCAAAAGATGAGTTTGATTTAGATATGAAAAATT
CTATCTTTATCGGAGATAATCTAAGCGATATGCAAGCAGGATTAAATGCTGATATTGGCACTTTGATTTTAGTAAATGAA
GAAAAAAAAGGCAATTTTTTTAAGCAATTTAAAAATTTAAAAGAAATTTTGCGCTTTCTTAAAGAAAAGGACATTTAA

Upstream 100 bases:

>100_bases
CTACTAATAATTTTTTCATTTGTTTTCTCCTTAGTAAAAATTAGATTACTGGGTATTGTATATCTTTATCTTTAATAAAA
ATCTTAAGAAATTAAAGATA

Downstream 100 bases:

>100_bases
ATGAAAATAGCAATCACAGGTGGTGCAGGATTTATAGGTTCGCAACTGGCTTTAAATTTGCAAGAAAAACATGAAATTTT
AATCATCGATAAAATGCGTA

Product: putative hydrolase

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MFIFFLKKLYYNVFMKTKALFLDRDGVINIDKKYVYKIEDFEFCDGIFELCRYFLARNYLLFIATNQSGIARGYYKESDF
FKLCDYMLKEFAKQDIKIDKIYYCPHLEGCECRKPKAGMLLKAKDEFDLDMKNSIFIGDNLSDMQAGLNADIGTLILVNE
EKKGNFFKQFKNLKEILRFLKEKDI

Sequences:

>Translated_185_residues
MFIFFLKKLYYNVFMKTKALFLDRDGVINIDKKYVYKIEDFEFCDGIFELCRYFLARNYLLFIATNQSGIARGYYKESDF
FKLCDYMLKEFAKQDIKIDKIYYCPHLEGCECRKPKAGMLLKAKDEFDLDMKNSIFIGDNLSDMQAGLNADIGTLILVNE
EKKGNFFKQFKNLKEILRFLKEKDI
>Mature_185_residues
MFIFFLKKLYYNVFMKTKALFLDRDGVINIDKKYVYKIEDFEFCDGIFELCRYFLARNYLLFIATNQSGIARGYYKESDF
FKLCDYMLKEFAKQDIKIDKIYYCPHLEGCECRKPKAGMLLKAKDEFDLDMKNSIFIGDNLSDMQAGLNADIGTLILVNE
EKKGNFFKQFKNLKEILRFLKEKDI

Specific function: Converts the D-glycero-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-D-manno-heptose 1-phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=157, Percent_Identity=43.9490445859873, Blast_Score=149, Evalue=1e-37,
Organism=Escherichia coli, GI87082027, Length=146, Percent_Identity=30.8219178082192, Blast_Score=80, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR004446
- InterPro:   IPR006543
- InterPro:   IPR013954 [H]

Pfam domain/function: PF08645 PNK3P [H]

EC number: 3.1.1.-

Molecular weight: Translated: 21978; Mature: 21978

Theoretical pI: Translated: 8.33; Mature: 8.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFIFFLKKLYYNVFMKTKALFLDRDGVINIDKKYVYKIEDFEFCDGIFELCRYFLARNYL
CHHHHHHHHHHHHHHHHHHEEECCCCEEEECCEEEEEECCHHHHHHHHHHHHHHHHCCEE
LFIATNQSGIARGYYKESDFFKLCDYMLKEFAKQDIKIDKIYYCPHLEGCECRKPKAGML
EEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCE
LKAKDEFDLDMKNSIFIGDNLSDMQAGLNADIGTLILVNEEKKGNFFKQFKNLKEILRFL
EEECCCCCCCCCCCEEECCCHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHH
KEKDI
HHCCC
>Mature Secondary Structure
MFIFFLKKLYYNVFMKTKALFLDRDGVINIDKKYVYKIEDFEFCDGIFELCRYFLARNYL
CHHHHHHHHHHHHHHHHHHEEECCCCEEEECCEEEEEECCHHHHHHHHHHHHHHHHCCEE
LFIATNQSGIARGYYKESDFFKLCDYMLKEFAKQDIKIDKIYYCPHLEGCECRKPKAGML
EEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCE
LKAKDEFDLDMKNSIFIGDNLSDMQAGLNADIGTLILVNEEKKGNFFKQFKNLKEILRFL
EEECCCCCCCCCCCEEECCCHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHH
KEKDI
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10688204; 12101286 [H]