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The map label for this gene is coaE [H]

Identifier: 153951069

GI number: 153951069

Start: 1661756

End: 1662361

Strand: Direct

Name: coaE [H]

Synonym: JJD26997_1882

Alternate gene names: 153951069

Gene position: 1661756-1662361 (Clockwise)

Preceding gene: 153951060

Following gene: 153951653

Centisome position: 90.06

GC content: 27.39

Gene sequence:

>606_bases
ATGAAAAATGCTTTTTTTGTAACCGCTTCAATTGCTTGTGGTAAAAGCACTTTTATAGAAATAGCGAATTCTTTAGGCTT
TAAAAGTATTAGCGCAGATAAAATCGCTCATGAAATTTTAGATGAAAATGCTTTAGAACTTGAAAAGATTTTTTCTCCCT
TTAGCTTAAAAAATTTACTCACAAAAGAAAAGAAAATCGATAGAAAAATCCTTGGAGAAATTGTTTTTAATAACAAAGAA
GCTAAAAAAACCTTAGAAAATTTCACTCATCCTAAAATTCGAGCTAAAATTTTAGAACAGATGCAAATTCTAGATAAAAA
AAATAAAGCTTTTTTTGTAGAAATTCCTCTTTTTTTTGAAAGCGATGCTTATGAAAATTTAGGCAAAATCATAGTAATTT
ACGCATCTAAAGAATTAAGCCTTAAAAGAATCATGCAAAGAGATAAGCTCAGCTTAGAAGCTGCAAAAGCCAGACTTGAT
TCTCAAATAGATATTGAAGAAAAACTTAAAAAAGCAGATTTTATCATTAAAAATACTAATTCTTATGCCGATTTTAGGCA
AGAATGTGTTAAAGTAATACAAGAAATTTCTAAAGGAAAAATGTGA

Upstream 100 bases:

>100_bases
ATCTATACTTACACCTGCATCTTCGTATGAAATTTTCATTTATTTTCCTTTAAGAACTAAAAAGGTATTTTAACGAAAAA
AGTTTTAATAAGGCATAAGA

Downstream 100 bases:

>100_bases
AATTTTATAAATATTGTGCAAGTGGAAATGATTTTGTCATAACAAATGCTGATAGAAAAGAAGATAGAAGTTCTTTAGCT
AAAGAACTTTGCAATCGTTA

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MKNAFFVTASIACGKSTFIEIANSLGFKSISADKIAHEILDENALELEKIFSPFSLKNLLTKEKKIDRKILGEIVFNNKE
AKKTLENFTHPKIRAKILEQMQILDKKNKAFFVEIPLFFESDAYENLGKIIVIYASKELSLKRIMQRDKLSLEAAKARLD
SQIDIEEKLKKADFIIKNTNSYADFRQECVKVIQEISKGKM

Sequences:

>Translated_201_residues
MKNAFFVTASIACGKSTFIEIANSLGFKSISADKIAHEILDENALELEKIFSPFSLKNLLTKEKKIDRKILGEIVFNNKE
AKKTLENFTHPKIRAKILEQMQILDKKNKAFFVEIPLFFESDAYENLGKIIVIYASKELSLKRIMQRDKLSLEAAKARLD
SQIDIEEKLKKADFIIKNTNSYADFRQECVKVIQEISKGKM
>Mature_201_residues
MKNAFFVTASIACGKSTFIEIANSLGFKSISADKIAHEILDENALELEKIFSPFSLKNLLTKEKKIDRKILGEIVFNNKE
AKKTLENFTHPKIRAKILEQMQILDKKNKAFFVEIPLFFESDAYENLGKIIVIYASKELSLKRIMQRDKLSLEAAKARLD
SQIDIEEKLKKADFIIKNTNSYADFRQECVKVIQEISKGKM

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=194, Percent_Identity=25.7731958762887, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI191252795, Length=194, Percent_Identity=25.7731958762887, Blast_Score=96, Evalue=3e-20,
Organism=Escherichia coli, GI1786292, Length=181, Percent_Identity=30.939226519337, Blast_Score=81, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17554944, Length=194, Percent_Identity=28.8659793814433, Blast_Score=99, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6320402, Length=200, Percent_Identity=30.5, Blast_Score=105, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24644728, Length=177, Percent_Identity=34.4632768361582, Blast_Score=101, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 23055; Mature: 23055

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNAFFVTASIACGKSTFIEIANSLGFKSISADKIAHEILDENALELEKIFSPFSLKNLL
CCCEEEEEEEECCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHCCHHHHHHH
TKEKKIDRKILGEIVFNNKEAKKTLENFTHPKIRAKILEQMQILDKKNKAFFVEIPLFFE
HHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEEC
SDAYENLGKIIVIYASKELSLKRIMQRDKLSLEAAKARLDSQIDIEEKLKKADFIIKNTN
CCCHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCEEEECCC
SYADFRQECVKVIQEISKGKM
CHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKNAFFVTASIACGKSTFIEIANSLGFKSISADKIAHEILDENALELEKIFSPFSLKNLL
CCCEEEEEEEECCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHCCHHHHHHH
TKEKKIDRKILGEIVFNNKEAKKTLENFTHPKIRAKILEQMQILDKKNKAFFVEIPLFFE
HHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEEC
SDAYENLGKIIVIYASKELSLKRIMQRDKLSLEAAKARLDSQIDIEEKLKKADFIIKNTN
CCCHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCEEEECCC
SYADFRQECVKVIQEISKGKM
CHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10688204 [H]