BacMap

Definition	Campylobacter jejuni subsp. doylei 269.97, complete genome.
Accession	NC_009707
Length	1,845,106

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The map label for this gene is ppiB [H]

Identifier: 153950978

GI number: 153950978

Start: 503961

End: 504443

Strand: Direct

Name: ppiB [H]

Synonym: JJD26997_0558

Alternate gene names: 153950978

Gene position: 503961-504443 (Clockwise)

Preceding gene: 153950953

Following gene: 153952187

Centisome position: 27.31

GC content: 36.23

Gene sequence:

>483_bases
ATGATAAAAACAATCGATACAAGCAAGGTAAACGAATACAAATTTGCTCTTATAAAAACTGAAAAAGGTATAATGAAACT
AAAACTTTTTGGTGATGAGGCTCCACAAACGGTTTGTAATTTTGCTACTTTAGCTAATGAAGGATTTTATAAAGATTTAA
ATTTCCATCGTGTGATTCCAAATTTTGTCATACAAGGGGGTTGTCCACACGGCAATGGTATAGGTGGGCCTGGATATGAA
ATCATTTGCGAATGTGATGATCAAGAACATAAACATGAGCGTGGAGCCTTATCTATGGCGCACGCAGGACGCGATACGGG
TGGCTCTCAATTTTTCATTTGTCACAGCCCTCAAGCTCATTTAGACGGGGTTCATACTGTTTTTGGGCAAATTGATCCAA
AAGATGAAGAAAGTTTGGAAGTTTTAGACTCTATACGCCAAGGAGATAAAATTTTAGACATAAAAATTTGCGATAAAATT
TAA

Upstream 100 bases:

>100_bases
TAGCAAGGAACAGCTTAGCGATATAGAAAAACTTTTAGATAAGTTAGAAGATGATGATGACGTTCAAGCTGTTTATACAA
ATATAGATTAAGGAGACATA

Downstream 100 bases:

>100_bases
AACTTTTTTGAAACTACAATATTTACAAAGCTAGTCATAAGTTTGACTAGCTAAAAATGATTAATATATAATTTTTTTTA
AACTTTTTTCTATAATCACA

Product: peptidyl-prolyl cis-trans isomerase B

Products: NA

Alternate protein names: PPIase; Rotamase [H]

Number of amino acids: Translated: 160; Mature: 160

Protein sequence:

>160_residues
MIKTIDTSKVNEYKFALIKTEKGIMKLKLFGDEAPQTVCNFATLANEGFYKDLNFHRVIPNFVIQGGCPHGNGIGGPGYE
IICECDDQEHKHERGALSMAHAGRDTGGSQFFICHSPQAHLDGVHTVFGQIDPKDEESLEVLDSIRQGDKILDIKICDKI

Sequences:

>Translated_160_residues
MIKTIDTSKVNEYKFALIKTEKGIMKLKLFGDEAPQTVCNFATLANEGFYKDLNFHRVIPNFVIQGGCPHGNGIGGPGYE
IICECDDQEHKHERGALSMAHAGRDTGGSQFFICHSPQAHLDGVHTVFGQIDPKDEESLEVLDSIRQGDKILDIKICDKI
>Mature_160_residues
MIKTIDTSKVNEYKFALIKTEKGIMKLKLFGDEAPQTVCNFATLANEGFYKDLNFHRVIPNFVIQGGCPHGNGIGGPGYE
IICECDDQEHKHERGALSMAHAGRDTGGSQFFICHSPQAHLDGVHTVFGQIDPKDEESLEVLDSIRQGDKILDIKICDKI

Specific function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides [H]

COG id: COG0652

COG function: function code O; Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase cyclophilin-type domain [H]

Homologues:

Organism=Homo sapiens, GI7706339, Length=118, Percent_Identity=44.0677966101695, Blast_Score=98, Evalue=3e-21,
Organism=Homo sapiens, GI24308049, Length=122, Percent_Identity=45.9016393442623, Blast_Score=93, Evalue=8e-20,
Organism=Homo sapiens, GI64276486, Length=118, Percent_Identity=38.135593220339, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI4758950, Length=123, Percent_Identity=43.9024390243902, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI4826932, Length=123, Percent_Identity=44.7154471544715, Blast_Score=84, Evalue=5e-17,
Organism=Homo sapiens, GI19557636, Length=133, Percent_Identity=36.8421052631579, Blast_Score=82, Evalue=2e-16,
Organism=Homo sapiens, GI6631100, Length=152, Percent_Identity=38.8157894736842, Blast_Score=80, Evalue=6e-16,
Organism=Homo sapiens, GI10863927, Length=147, Percent_Identity=39.4557823129252, Blast_Score=79, Evalue=1e-15,
Organism=Homo sapiens, GI256017253, Length=122, Percent_Identity=43.4426229508197, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI221139811, Length=122, Percent_Identity=43.4426229508197, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI256017251, Length=122, Percent_Identity=43.4426229508197, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI178057341, Length=120, Percent_Identity=44.1666666666667, Blast_Score=78, Evalue=4e-15,
Organism=Homo sapiens, GI4505991, Length=117, Percent_Identity=46.1538461538462, Blast_Score=77, Evalue=5e-15,
Organism=Homo sapiens, GI310129267, Length=133, Percent_Identity=42.1052631578947, Blast_Score=77, Evalue=6e-15,
Organism=Homo sapiens, GI310120620, Length=133, Percent_Identity=42.1052631578947, Blast_Score=77, Evalue=6e-15,
Organism=Homo sapiens, GI42560244, Length=143, Percent_Identity=38.4615384615385, Blast_Score=74, Evalue=4e-14,
Organism=Homo sapiens, GI310110104, Length=149, Percent_Identity=39.5973154362416, Blast_Score=74, Evalue=4e-14,
Organism=Homo sapiens, GI209417936, Length=120, Percent_Identity=43.3333333333333, Blast_Score=74, Evalue=5e-14,
Organism=Homo sapiens, GI30102944, Length=120, Percent_Identity=43.3333333333333, Blast_Score=74, Evalue=5e-14,
Organism=Homo sapiens, GI219842199, Length=120, Percent_Identity=43.3333333333333, Blast_Score=74, Evalue=5e-14,
Organism=Homo sapiens, GI310132444, Length=146, Percent_Identity=41.0958904109589, Blast_Score=74, Evalue=5e-14,
Organism=Homo sapiens, GI310113152, Length=146, Percent_Identity=41.0958904109589, Blast_Score=74, Evalue=5e-14,
Organism=Homo sapiens, GI310127646, Length=151, Percent_Identity=36.4238410596026, Blast_Score=73, Evalue=1e-13,
Organism=Homo sapiens, GI310114371, Length=151, Percent_Identity=36.4238410596026, Blast_Score=73, Evalue=1e-13,
Organism=Homo sapiens, GI310119221, Length=151, Percent_Identity=36.4238410596026, Blast_Score=73, Evalue=1e-13,
Organism=Homo sapiens, GI169164185, Length=149, Percent_Identity=35.5704697986577, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI169163623, Length=149, Percent_Identity=35.5704697986577, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI5031987, Length=129, Percent_Identity=41.8604651162791, Blast_Score=71, Evalue=4e-13,
Organism=Homo sapiens, GI169163387, Length=149, Percent_Identity=35.5704697986577, Blast_Score=70, Evalue=6e-13,
Organism=Homo sapiens, GI5454154, Length=144, Percent_Identity=37.5, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI5174637, Length=137, Percent_Identity=40.8759124087591, Blast_Score=68, Evalue=4e-12,
Organism=Homo sapiens, GI45439316, Length=136, Percent_Identity=39.7058823529412, Blast_Score=68, Evalue=4e-12,
Organism=Homo sapiens, GI303305009, Length=141, Percent_Identity=39.0070921985816, Blast_Score=67, Evalue=5e-12,
Organism=Homo sapiens, GI150418007, Length=113, Percent_Identity=41.5929203539823, Blast_Score=67, Evalue=9e-12,
Organism=Homo sapiens, GI22547212, Length=125, Percent_Identity=40, Blast_Score=63, Evalue=9e-11,
Organism=Homo sapiens, GI7657473, Length=125, Percent_Identity=40, Blast_Score=63, Evalue=9e-11,
Organism=Homo sapiens, GI22547215, Length=125, Percent_Identity=40, Blast_Score=63, Evalue=9e-11,
Organism=Escherichia coli, GI1789763, Length=138, Percent_Identity=36.231884057971, Blast_Score=70, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17539496, Length=124, Percent_Identity=41.9354838709677, Blast_Score=101, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17532641, Length=131, Percent_Identity=39.6946564885496, Blast_Score=94, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17506311, Length=125, Percent_Identity=45.6, Blast_Score=94, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17552780, Length=134, Percent_Identity=44.7761194029851, Blast_Score=84, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17506307, Length=136, Percent_Identity=41.1764705882353, Blast_Score=81, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71997782, Length=139, Percent_Identity=35.9712230215827, Blast_Score=80, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17559074, Length=154, Percent_Identity=36.3636363636364, Blast_Score=77, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71980594, Length=142, Percent_Identity=36.6197183098592, Blast_Score=77, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI71980590, Length=137, Percent_Identity=37.2262773722628, Blast_Score=77, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17566266, Length=122, Percent_Identity=40.1639344262295, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17565860, Length=123, Percent_Identity=42.2764227642276, Blast_Score=74, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17552782, Length=140, Percent_Identity=37.1428571428571, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17551284, Length=137, Percent_Identity=39.4160583941606, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17551282, Length=137, Percent_Identity=39.4160583941606, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17539498, Length=131, Percent_Identity=37.4045801526718, Blast_Score=69, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17552784, Length=144, Percent_Identity=34.7222222222222, Blast_Score=66, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17532643, Length=121, Percent_Identity=39.6694214876033, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6320510, Length=117, Percent_Identity=43.5897435897436, Blast_Score=80, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6321848, Length=118, Percent_Identity=44.0677966101695, Blast_Score=79, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6320359, Length=115, Percent_Identity=45.2173913043478, Blast_Score=78, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6323562, Length=122, Percent_Identity=41.8032786885246, Blast_Score=78, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6323246, Length=125, Percent_Identity=39.2, Blast_Score=67, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17986117, Length=126, Percent_Identity=42.0634920634921, Blast_Score=100, Evalue=5e-22,
Organism=Drosophila melanogaster, GI19922376, Length=132, Percent_Identity=38.6363636363636, Blast_Score=94, Evalue=5e-20,
Organism=Drosophila melanogaster, GI21357249, Length=118, Percent_Identity=38.135593220339, Blast_Score=87, Evalue=4e-18,
Organism=Drosophila melanogaster, GI20130249, Length=132, Percent_Identity=43.9393939393939, Blast_Score=85, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24650807, Length=152, Percent_Identity=39.4736842105263, Blast_Score=84, Evalue=4e-17,
Organism=Drosophila melanogaster, GI45549139, Length=129, Percent_Identity=44.1860465116279, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24664125, Length=115, Percent_Identity=44.3478260869565, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21357783, Length=115, Percent_Identity=44.3478260869565, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI19922912, Length=140, Percent_Identity=37.8571428571429, Blast_Score=74, Evalue=4e-14,
Organism=Drosophila melanogaster, GI17647301, Length=118, Percent_Identity=40.6779661016949, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24586038, Length=130, Percent_Identity=37.6923076923077, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24652460, Length=119, Percent_Identity=34.453781512605, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI17136360, Length=138, Percent_Identity=36.9565217391304, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015891
- InterPro:   IPR020892
- InterPro:   IPR002130 [H]

Pfam domain/function: PF00160 Pro_isomerase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 17718; Mature: 17718

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: PS00170 CSA_PPIASE_1 ; PS50072 CSA_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKTIDTSKVNEYKFALIKTEKGIMKLKLFGDEAPQTVCNFATLANEGFYKDLNFHRVIP
CCCCCCCCCCCCEEEEEEEECCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCEEECC
NFVIQGGCPHGNGIGGPGYEIICECDDQEHKHERGALSMAHAGRDTGGSQFFICHSPQAH
CCEEECCCCCCCCCCCCCEEEEEECCCCHHHHHHCCEEEHHCCCCCCCCEEEEEECCCHH
LDGVHTVFGQIDPKDEESLEVLDSIRQGDKILDIKICDKI
HCCHHHHHCCCCCCCCHHHHHHHHHHCCCEEEEEEECCCC
>Mature Secondary Structure
MIKTIDTSKVNEYKFALIKTEKGIMKLKLFGDEAPQTVCNFATLANEGFYKDLNFHRVIP
CCCCCCCCCCCCEEEEEEEECCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCEEECC
NFVIQGGCPHGNGIGGPGYEIICECDDQEHKHERGALSMAHAGRDTGGSQFFICHSPQAH
CCEEECCCCCCCCCCCCCEEEEEECCCCHHHHHHCCEEEHHCCCCCCCCEEEEEECCCHH
LDGVHTVFGQIDPKDEESLEVLDSIRQGDKILDIKICDKI
HCCHHHHHCCCCCCCCHHHHHHHHHHCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA