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The map label for this gene is shlB [H]

Identifier: 153950832

GI number: 153950832

Start: 346478

End: 348166

Strand: Reverse

Name: shlB [H]

Synonym: YpsIP31758_0300

Alternate gene names: 153950832

Gene position: 348166-346478 (Counterclockwise)

Preceding gene: 153948320

Following gene: 153949445

Centisome position: 7.37

GC content: 46.54

Gene sequence:

>1689_bases
ATGATTAGAAAACGTACTGCGTTATGGCTTGTACTCAGTACTGGCGCTCAAGCCGAGACGCCTTTGGCCATAGAGACCCC
ATTTCCCATTAATGAATCTCGCCAGTCATTACAAAATAATGCTAAAGAAATTAATCAGTTAATAGAAGAAAAGCGCCACC
AACAGATAACGCAACGCAACACCGGACAAGGTGAATTATCTCGCCCGGAAAACCCCGCTGCGCCAGAGCTGCCAGAAGAT
ACACAGTGCTTGCCCATTAATGGTGTTTATATTCAGGGGATCACCTTATTAACAGAGGATGATTTAAATGAATTAAGTGC
GATACCTGAACAATGTATTCATCCGGAGAACATTAACCTTCTGACCCGTGAACTCACTAATATCTATATGGATAAAGGGT
ATATCACGGCACGTATTCAATTTATTCCACCAGATGCTGATGGGAAGTTAGGTCTGGATATTACCGAAGGGTTTGTCGAA
GCGATTGATAGCACGGACACCGGGTTAGATGGTGAGACAGTCTTCCCGAATATGATCGGTAAGCCGCTCAATATTACTCG
CCTTGACCAAGGGTTGGACCAGGCAAACCGTTTGCCCTCAAATAAAGTCACCGTCGATATTCTGCCCGGAACACTGCCCG
GTGGATCTATTCTTAAACTGCATAATACACCGTCAACCCCTTGGCATTTGACCACCTCACTCGACAATTACGGCAATAAA
AATACCGGTGAATGGCTAAATCGCAACGCCTTGTCTTTTGATAATCCACTGGGCTTATCGGATTCTGTCAGTATCAATAT
CAGTAATACCGTTGATCGCCCCCAACATAATTATAGCCGTGCTTACTCAATGTTTTATTCGGTCCCCTACGGTGCCTTGA
CCTTTAGTGGCTTTGGCAGTTATGCCGAATACCGCTATCCGCTGAAATTGCAGTTTAATACAGTCAAGTTACATGGAGAA
ACACAGCAACACGGTTTACGGGCAGATTATGTTTTCTATCGCGATCAAAACCAGATTAATGGGCTAAGTGCGCAATTAAC
CTATAAACGGGCCAGTAATTATCTGAATGAAGAAAAAATTGCGATCAGCAGCCCGACGCTAACAATCTTTGAATTAGGTC
TTAATCACCTGCACGTCCTGCCAATGGGTCTGTTTAATATCAATGTCAGCATTGAGCAGGGCTTGCCTTGGCTGGGCGCC
GAGCGCTCAAATGGCCCATTAGCGAACTATCAGGATAGCCAATTCACTAAAGCTAAGGCTTCAATTACTTCCAATCACTA
TTTTGCACTGTTTGATGATGCCTATCTGCTCAGCAATCAATTTTATGGCCAGTACACCCGTGACCGGTTACCCGGTGTGG
AATGGCTCAGCATCACTGACAGCACTGCCATCCGTGGCTTTAGCCGCAATACCTTATCCGCCGATCAAGGCTGGTACTTA
CAAAATACCCTTTCCCGTCGTTTCACCTTGGGTGACGCCACGCTAACCCCTCGCGTAGGCCTGGATACGGGCCGTATCCA
GCAAAAGCCACAGGGGTGGGTCAGCGCTATGGGGCTAAGCGCTGGCGTCAGCCTTAATTACCAGAATGCCACATTGGATA
TAGAGGCCAGCCGCGGCCACTTACTCTCCGGCCCATCGAAGATTAACGATCCAACACAAATTCTGGCGCGTTTTTCTTAC
CGCTTTTAA

Upstream 100 bases:

>100_bases
AGGGACGGTAATTGTGCTGCCCGTCAATTTGACTCAGGGACAGAAAGAGCTGCGCCTGCAAATAAATTTGTTCGGTCAGT
CTATTTCTCAATCAGATATT

Downstream 100 bases:

>100_bases
TGCAATTTTCCCTTGAGAACACCTTGTTACTCATACCAGGAAATATCACCCCAAAATGGAGATGTAAAAATGAAGAAACA
CACCTTTAAGCTCTCACCGG

Product: hemolysin activator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 562; Mature: 562

Protein sequence:

>562_residues
MIRKRTALWLVLSTGAQAETPLAIETPFPINESRQSLQNNAKEINQLIEEKRHQQITQRNTGQGELSRPENPAAPELPED
TQCLPINGVYIQGITLLTEDDLNELSAIPEQCIHPENINLLTRELTNIYMDKGYITARIQFIPPDADGKLGLDITEGFVE
AIDSTDTGLDGETVFPNMIGKPLNITRLDQGLDQANRLPSNKVTVDILPGTLPGGSILKLHNTPSTPWHLTTSLDNYGNK
NTGEWLNRNALSFDNPLGLSDSVSINISNTVDRPQHNYSRAYSMFYSVPYGALTFSGFGSYAEYRYPLKLQFNTVKLHGE
TQQHGLRADYVFYRDQNQINGLSAQLTYKRASNYLNEEKIAISSPTLTIFELGLNHLHVLPMGLFNINVSIEQGLPWLGA
ERSNGPLANYQDSQFTKAKASITSNHYFALFDDAYLLSNQFYGQYTRDRLPGVEWLSITDSTAIRGFSRNTLSADQGWYL
QNTLSRRFTLGDATLTPRVGLDTGRIQQKPQGWVSAMGLSAGVSLNYQNATLDIEASRGHLLSGPSKINDPTQILARFSY
RF

Sequences:

>Translated_562_residues
MIRKRTALWLVLSTGAQAETPLAIETPFPINESRQSLQNNAKEINQLIEEKRHQQITQRNTGQGELSRPENPAAPELPED
TQCLPINGVYIQGITLLTEDDLNELSAIPEQCIHPENINLLTRELTNIYMDKGYITARIQFIPPDADGKLGLDITEGFVE
AIDSTDTGLDGETVFPNMIGKPLNITRLDQGLDQANRLPSNKVTVDILPGTLPGGSILKLHNTPSTPWHLTTSLDNYGNK
NTGEWLNRNALSFDNPLGLSDSVSINISNTVDRPQHNYSRAYSMFYSVPYGALTFSGFGSYAEYRYPLKLQFNTVKLHGE
TQQHGLRADYVFYRDQNQINGLSAQLTYKRASNYLNEEKIAISSPTLTIFELGLNHLHVLPMGLFNINVSIEQGLPWLGA
ERSNGPLANYQDSQFTKAKASITSNHYFALFDDAYLLSNQFYGQYTRDRLPGVEWLSITDSTAIRGFSRNTLSADQGWYL
QNTLSRRFTLGDATLTPRVGLDTGRIQQKPQGWVSAMGLSAGVSLNYQNATLDIEASRGHLLSGPSKINDPTQILARFSY
RF
>Mature_562_residues
MIRKRTALWLVLSTGAQAETPLAIETPFPINESRQSLQNNAKEINQLIEEKRHQQITQRNTGQGELSRPENPAAPELPED
TQCLPINGVYIQGITLLTEDDLNELSAIPEQCIHPENINLLTRELTNIYMDKGYITARIQFIPPDADGKLGLDITEGFVE
AIDSTDTGLDGETVFPNMIGKPLNITRLDQGLDQANRLPSNKVTVDILPGTLPGGSILKLHNTPSTPWHLTTSLDNYGNK
NTGEWLNRNALSFDNPLGLSDSVSINISNTVDRPQHNYSRAYSMFYSVPYGALTFSGFGSYAEYRYPLKLQFNTVKLHGE
TQQHGLRADYVFYRDQNQINGLSAQLTYKRASNYLNEEKIAISSPTLTIFELGLNHLHVLPMGLFNINVSIEQGLPWLGA
ERSNGPLANYQDSQFTKAKASITSNHYFALFDDAYLLSNQFYGQYTRDRLPGVEWLSITDSTAIRGFSRNTLSADQGWYL
QNTLSRRFTLGDATLTPRVGLDTGRIQQKPQGWVSAMGLSAGVSLNYQNATLDIEASRGHLLSGPSKINDPTQILARFSY
RF

Specific function: Member of a two partner secretion pathway (TPS) in which it mediates the secretion of hemolysin [H]

COG id: COG2831

COG function: function code U; Hemolysin activation/secretion protein

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tpsB (TC 1.B.20) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005565
- InterPro:   IPR013686 [H]

Pfam domain/function: PF08479 POTRA_2; PF03865 ShlB [H]

EC number: NA

Molecular weight: Translated: 62683; Mature: 62683

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRKRTALWLVLSTGAQAETPLAIETPFPINESRQSLQNNAKEINQLIEEKRHQQITQRN
CCCCEEEEEEEEECCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TGQGELSRPENPAAPELPEDTQCLPINGVYIQGITLLTEDDLNELSAIPEQCIHPENINL
CCCCCCCCCCCCCCCCCCCCCCEEEECCEEEEEEEEEECCCHHHHHHHHHHHCCCCCCHH
LTRELTNIYMDKGYITARIQFIPPDADGKLGLDITEGFVEAIDSTDTGLDGETVFPNMIG
HHHHHHHHHCCCCEEEEEEEEECCCCCCEECCCHHHHHHHHHCCCCCCCCCCEECHHHCC
KPLNITRLDQGLDQANRLPSNKVTVDILPGTLPGGSILKLHNTPSTPWHLTTSLDNYGNK
CCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCEEEECCCCCCCEEEEECHHCCCCC
NTGEWLNRNALSFDNPLGLSDSVSINISNTVDRPQHNYSRAYSMFYSVPYGALTFSGFGS
CCHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCEEECCCCC
YAEYRYPLKLQFNTVKLHGETQQHGLRADYVFYRDQNQINGLSAQLTYKRASNYLNEEKI
CHHEECEEEEEEEEEEEECCHHHCCCEEEEEEEECCCCCCCEEEEEEHHHHHCCCCCCEE
AISSPTLTIFELGLNHLHVLPMGLFNINVSIEQGLPWLGAERSNGPLANYQDSQFTKAKA
EECCCCEEEEECCCCEEEEEEEEEEEEEEEHHCCCCCCCCCCCCCCCCCCCCCCHHHHHH
SITSNHYFALFDDAYLLSNQFYGQYTRDRLPGVEWLSITDSTAIRGFSRNTLSADQGWYL
EECCCCEEEEECCCEEECCCCCCCHHHHCCCCCEEEEECCCHHHCCCCCCCCCCCCCEEH
QNTLSRRFTLGDATLTPRVGLDTGRIQQKPQGWVSAMGLSAGVSLNYQNATLDIEASRGH
HHHHHHEEEECCCEECCCCCCCCCCCCCCCCHHHHHHCCCCCEEEEECCEEEEEECCCCC
LLSGPSKINDPTQILARFSYRF
EECCCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MIRKRTALWLVLSTGAQAETPLAIETPFPINESRQSLQNNAKEINQLIEEKRHQQITQRN
CCCCEEEEEEEEECCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TGQGELSRPENPAAPELPEDTQCLPINGVYIQGITLLTEDDLNELSAIPEQCIHPENINL
CCCCCCCCCCCCCCCCCCCCCCEEEECCEEEEEEEEEECCCHHHHHHHHHHHCCCCCCHH
LTRELTNIYMDKGYITARIQFIPPDADGKLGLDITEGFVEAIDSTDTGLDGETVFPNMIG
HHHHHHHHHCCCCEEEEEEEEECCCCCCEECCCHHHHHHHHHCCCCCCCCCCEECHHHCC
KPLNITRLDQGLDQANRLPSNKVTVDILPGTLPGGSILKLHNTPSTPWHLTTSLDNYGNK
CCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCEEEECCCCCCCEEEEECHHCCCCC
NTGEWLNRNALSFDNPLGLSDSVSINISNTVDRPQHNYSRAYSMFYSVPYGALTFSGFGS
CCHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCEEECCCCC
YAEYRYPLKLQFNTVKLHGETQQHGLRADYVFYRDQNQINGLSAQLTYKRASNYLNEEKI
CHHEECEEEEEEEEEEEECCHHHCCCEEEEEEEECCCCCCCEEEEEEHHHHHCCCCCCEE
AISSPTLTIFELGLNHLHVLPMGLFNINVSIEQGLPWLGAERSNGPLANYQDSQFTKAKA
EECCCCEEEEECCCCEEEEEEEEEEEEEEEHHCCCCCCCCCCCCCCCCCCCCCCHHHHHH
SITSNHYFALFDDAYLLSNQFYGQYTRDRLPGVEWLSITDSTAIRGFSRNTLSADQGWYL
EECCCCEEEEECCCEEECCCCCCCHHHHCCCCCEEEEECCCHHHCCCCCCCCCCCCCEEH
QNTLSRRFTLGDATLTPRVGLDTGRIQQKPQGWVSAMGLSAGVSLNYQNATLDIEASRGH
HHHHHHEEEECCCEECCCCCCCCCCCCCCCCHHHHHHCCCCCEEEEECCEEEEEECCCCC
LLSGPSKINDPTQILARFSYRF
EECCCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3290200 [H]