| Definition | Yersinia pseudotuberculosis IP 31758, complete genome. |
|---|---|
| Accession | NC_009708 |
| Length | 4,723,306 |
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The map label for this gene is uvrA [H]
Identifier: 153950806
GI number: 153950806
Start: 4236507
End: 4239350
Strand: Direct
Name: uvrA [H]
Synonym: YpsIP31758_3761
Alternate gene names: 153950806
Gene position: 4236507-4239350 (Clockwise)
Preceding gene: 153949563
Following gene: 153948239
Centisome position: 89.69
GC content: 51.97
Gene sequence:
>2844_bases ATGGATAATATTGAAGTTCGGGGCGCTCGCACCCACAATCTTAAGAATATCAACCTGATTATCCCGCGCGACAAACTGAT TGTTGTCACCGGCCTATCAGGTTCAGGCAAATCCTCACTGGCTTTTGATACCTTGTATGCCGAAGGTCAACGCCGTTATG TTGAGTCTCTCTCCGCCTATGCACGCCAATTTCTGTCGCTGATGGAAAAACCGGATGTTGACCATATTGAAGGCCTGTCT CCGGCTATCTCTATCGAGCAAAAATCAACCTCCCATAATCCACGGTCAACTGTCGGTACTATCACTGAAATCCATGATTA CCTGCGCTTGCTGTTCGCTCGAGTCGGCGAGCCGCGCTGCCCTGATCATGATGTCCCATTAGCGGCGCAAACAGTCAGCC AAATGGTTGATAACGTGATAAGCCAGCCGGAAGGCCGCCGTCTGATGCTGCTGGCACCGGTGGTAAAAGATCGCAAAGGT GAACACACTAAAATACTGGAAAATCTGGCCGCTCAAGGTTACATCCGGGCGCGGATCGATGGCGAGGTTTGTGATCTGTC TGATCCGCCCAAATTAGAGCTGCAAAAGAAACACACCATTGAAGTGGTGGTTGACCGTTTCAAGGTACGCGAAGATCTGG CGCAACGTTTGGCAGAATCATTTGAAACCGCACTGGCGTTATCCGGCGGTACCGCCGTGGTAGCCGATATGGACGATCCG CATGTGGAGGAGTTGTTATTTTCCGCTAACTTTGCCTGCCCGATTTGCGGTTACAGCATGAGAGAGTTGGAACCACGCCT GTTCTCCTTTAACAACCCGGCGGGTGCCTGCCCAACGTGTGATGGCTTGGGTGTCCAGCAGTTTTTTGATCCAGACCGCG TGCTGCAAAACCCTGAGCTCTCTTTAGCTGGCGGAGCGATTCGCGGCTGGGATCGCCGTAACTTCTATTACTTCCAGATG CTACGTTCACTGGCCGAGCATTATAAATTTGATATCGAAGCGCCGTTTAACTCACTGGACAGCGCCGTCCAGCAAGCCGT GCTATACGGTTCAGGCAAAGATACCATCGAGTTCAAGTACATTAATGATCGCGGTGATACTACCGTTCGCCGCCACCCTT TTGAGGGGGTGTTGCACAATATGGAACGCCGTTATAAAGAGACGGAATCCAGTGCGGTGCGCGAAGAGTTAGCCAAATTT ATCAGCAACCGCTCCTGTGCGTCATGCAGCGGTACCCGTCTGCGCAGAGAGGCTCGTTATGTCTTCGTGGAAAACACCAC CCTGCCAGAGATTTCTGAACTGAGCATCGGCCATGCACTGAGTTTCTTCCAGAATATGAAGCTCAGTGGTCAGCGTGCAC AAATCGCTGAAAAGATACTGAAAGAAATTGGCGATAGGCTGAAATTCCTGGTTAACGTCGGGCTGAATTATCTGTCTTTA TCCCGATCTGCCGAAACCCTGTCCGGTGGCGAAGCACAGCGTATCCGTCTGGCTAGCCAGATTGGCGCGGGTTTGGTCGG CGTTATGTATGTGCTGGATGAGCCGTCTATCGGTTTACATCAGCGCGATAACGAACGCTTGCTGGAGACATTGATTCACC TACGTAATCTGGGTAACACCGTGATTGTGGTGGAACATGATGAAGATGCCATCCGGGCCGCAGATCATGTGATTGATATC GGCCCTGGGGCCGGCGTGCACGGAGGTGAAGTTGTCGCCGAAGGAACGGTAGATGACATCATGGCCGCACCGGCGTCACT CACGGGCCAGTTCCTCAGCGGTAAGCGGAGCATCGCCATCCCAGAGAAACGGGTCAGTGCTGATCCGAGCAAAGTCTTAA AGCTGATAGGGGCTACGGGCAATAACCTGAAAGATGTCACTCTGACGCTGCCTGTCGGGCTATTCAGTTGCATCACCGGG GTCTCCGGCTCGGGGAAATCGACGCTAATCAACGATACTTTATACAGTATTGCCCAACGCCAACTGAACGGCGCGACCAT CACCGAACCCGCACCATACCGCGAGATCCAAGGGCTAGAACATTTCGATAAAGTCATCGACATTGATCAAAGCCCGATTG GCCGTACGCCGCGTTCTAACCCAGCCACCTATACCGGCATCTTTACCCCCATTCGCGAGTTATTTGCCGGAGTGCCGGAA TCACGCACCCGCGGTTATACGCCAGGCCGTTTCAGTTTTAACGTCAAAGGTGGGCGCTGCGAAGCCTGCCAGGGCGATGG GGTAATTAAAGTAGAAATGCACTTTCTGCCTGATATTTATGTTCCTTGCGATCACTGTAAAGGTAAGCGTTATAACCGTG AAACGCTGGAAATAAAATATAAAGGTAAAAGTATTCACGAAGTTCTGGCGATGACTATTGAAGAGGCCCGCGAGTTCTTT GATGCCGTACCTGCTCTGGCACGTAAGCTGCAAACCCTAATAGATGTTGGCCTGTCCTATATTTGTCTGGGCCAATCAGC CACAACGTTATCTGGTGGGGAAGCACAGCGGGTGAAACTATCGCGCGAACTGTCAAAACGCGGGACCGGCCAGACATTGT ATATTCTGGATGAGCCTACTACCGGCCTGCATTTTGCCGATATTCAGCAACTGCTAGCGGTATTGCATCAGTTACGGGAT CAGGGCAATACCATTGTAGTGATTGAACACAATCTGGACGTAATTAAGACGGCGGATTGGATTGTCGATCTGGGGCCAGA AGGCGGCAGTGGTGGCGGTGAAATTTTGGTCTCCGGCACACCAGAGACGGTGGCGGAATGCGCGGTATCACACACGGCAC GGTTCCTTAAGCCGATGTTGCAGCGTAAGCCACAAACCGTTTAA
Upstream 100 bases:
>100_bases GATTCGGGTGAGTGAGCGCAGCTAACAACCCTGCAGCTTCAAGTACGAAGAGTAAAAAAAGGCACGCTGAGAGGCTCAGT TCAATCCGGGAAGAGTTTGA
Downstream 100 bases:
>100_bases TGAACCACTCTGGGGCAATCAATGTATTGCTCCAGAGGGTATGACATTCAGCGTTTTGATCATCAAACTATTCATCCCTA AAATCATTGACGTTACAGAT
Product: excinuclease ABC subunit A
Products: NA
Alternate protein names: UvrA protein; Excinuclease ABC subunit A [H]
Number of amino acids: Translated: 947; Mature: 947
Protein sequence:
>947_residues MDNIEVRGARTHNLKNINLIIPRDKLIVVTGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLSLMEKPDVDHIEGLS PAISIEQKSTSHNPRSTVGTITEIHDYLRLLFARVGEPRCPDHDVPLAAQTVSQMVDNVISQPEGRRLMLLAPVVKDRKG EHTKILENLAAQGYIRARIDGEVCDLSDPPKLELQKKHTIEVVVDRFKVREDLAQRLAESFETALALSGGTAVVADMDDP HVEELLFSANFACPICGYSMRELEPRLFSFNNPAGACPTCDGLGVQQFFDPDRVLQNPELSLAGGAIRGWDRRNFYYFQM LRSLAEHYKFDIEAPFNSLDSAVQQAVLYGSGKDTIEFKYINDRGDTTVRRHPFEGVLHNMERRYKETESSAVREELAKF ISNRSCASCSGTRLRREARYVFVENTTLPEISELSIGHALSFFQNMKLSGQRAQIAEKILKEIGDRLKFLVNVGLNYLSL SRSAETLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLLETLIHLRNLGNTVIVVEHDEDAIRAADHVIDI GPGAGVHGGEVVAEGTVDDIMAAPASLTGQFLSGKRSIAIPEKRVSADPSKVLKLIGATGNNLKDVTLTLPVGLFSCITG VSGSGKSTLINDTLYSIAQRQLNGATITEPAPYREIQGLEHFDKVIDIDQSPIGRTPRSNPATYTGIFTPIRELFAGVPE SRTRGYTPGRFSFNVKGGRCEACQGDGVIKVEMHFLPDIYVPCDHCKGKRYNRETLEIKYKGKSIHEVLAMTIEEAREFF DAVPALARKLQTLIDVGLSYICLGQSATTLSGGEAQRVKLSRELSKRGTGQTLYILDEPTTGLHFADIQQLLAVLHQLRD QGNTIVVIEHNLDVIKTADWIVDLGPEGGSGGGEILVSGTPETVAECAVSHTARFLKPMLQRKPQTV
Sequences:
>Translated_947_residues MDNIEVRGARTHNLKNINLIIPRDKLIVVTGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLSLMEKPDVDHIEGLS PAISIEQKSTSHNPRSTVGTITEIHDYLRLLFARVGEPRCPDHDVPLAAQTVSQMVDNVISQPEGRRLMLLAPVVKDRKG EHTKILENLAAQGYIRARIDGEVCDLSDPPKLELQKKHTIEVVVDRFKVREDLAQRLAESFETALALSGGTAVVADMDDP HVEELLFSANFACPICGYSMRELEPRLFSFNNPAGACPTCDGLGVQQFFDPDRVLQNPELSLAGGAIRGWDRRNFYYFQM LRSLAEHYKFDIEAPFNSLDSAVQQAVLYGSGKDTIEFKYINDRGDTTVRRHPFEGVLHNMERRYKETESSAVREELAKF ISNRSCASCSGTRLRREARYVFVENTTLPEISELSIGHALSFFQNMKLSGQRAQIAEKILKEIGDRLKFLVNVGLNYLSL SRSAETLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLLETLIHLRNLGNTVIVVEHDEDAIRAADHVIDI GPGAGVHGGEVVAEGTVDDIMAAPASLTGQFLSGKRSIAIPEKRVSADPSKVLKLIGATGNNLKDVTLTLPVGLFSCITG VSGSGKSTLINDTLYSIAQRQLNGATITEPAPYREIQGLEHFDKVIDIDQSPIGRTPRSNPATYTGIFTPIRELFAGVPE SRTRGYTPGRFSFNVKGGRCEACQGDGVIKVEMHFLPDIYVPCDHCKGKRYNRETLEIKYKGKSIHEVLAMTIEEAREFF DAVPALARKLQTLIDVGLSYICLGQSATTLSGGEAQRVKLSRELSKRGTGQTLYILDEPTTGLHFADIQQLLAVLHQLRD QGNTIVVIEHNLDVIKTADWIVDLGPEGGSGGGEILVSGTPETVAECAVSHTARFLKPMLQRKPQTV >Mature_947_residues MDNIEVRGARTHNLKNINLIIPRDKLIVVTGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLSLMEKPDVDHIEGLS PAISIEQKSTSHNPRSTVGTITEIHDYLRLLFARVGEPRCPDHDVPLAAQTVSQMVDNVISQPEGRRLMLLAPVVKDRKG EHTKILENLAAQGYIRARIDGEVCDLSDPPKLELQKKHTIEVVVDRFKVREDLAQRLAESFETALALSGGTAVVADMDDP HVEELLFSANFACPICGYSMRELEPRLFSFNNPAGACPTCDGLGVQQFFDPDRVLQNPELSLAGGAIRGWDRRNFYYFQM LRSLAEHYKFDIEAPFNSLDSAVQQAVLYGSGKDTIEFKYINDRGDTTVRRHPFEGVLHNMERRYKETESSAVREELAKF ISNRSCASCSGTRLRREARYVFVENTTLPEISELSIGHALSFFQNMKLSGQRAQIAEKILKEIGDRLKFLVNVGLNYLSL SRSAETLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLLETLIHLRNLGNTVIVVEHDEDAIRAADHVIDI GPGAGVHGGEVVAEGTVDDIMAAPASLTGQFLSGKRSIAIPEKRVSADPSKVLKLIGATGNNLKDVTLTLPVGLFSCITG VSGSGKSTLINDTLYSIAQRQLNGATITEPAPYREIQGLEHFDKVIDIDQSPIGRTPRSNPATYTGIFTPIRELFAGVPE SRTRGYTPGRFSFNVKGGRCEACQGDGVIKVEMHFLPDIYVPCDHCKGKRYNRETLEIKYKGKSIHEVLAMTIEEAREFF DAVPALARKLQTLIDVGLSYICLGQSATTLSGGEAQRVKLSRELSKRGTGQTLYILDEPTTGLHFADIQQLLAVLHQLRD QGNTIVVIEHNLDVIKTADWIVDLGPEGGSGGGEILVSGTPETVAECAVSHTARFLKPMLQRKPQTV
Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion h
COG id: COG0178
COG function: function code L; Excinuclease ATPase subunit
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 2 ABC transporter domains [H]
Homologues:
Organism=Escherichia coli, GI2367343, Length=940, Percent_Identity=90.8510638297872, Blast_Score=1763, Evalue=0.0,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR017871 - InterPro: IPR013815 - InterPro: IPR004602 [H]
Pfam domain/function: PF00005 ABC_tran [H]
EC number: NA
Molecular weight: Translated: 104285; Mature: 104285
Theoretical pI: Translated: 6.42; Mature: 6.42
Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.6 %Cys (Translated Protein) 1.5 %Met (Translated Protein) 3.1 %Cys+Met (Translated Protein) 1.6 %Cys (Mature Protein) 1.5 %Met (Mature Protein) 3.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MDNIEVRGARTHNLKNINLIIPRDKLIVVTGLSGSGKSSLAFDTLYAEGQRRYVESLSAY CCCCEECCCCCCCCCEEEEEECCCCEEEEECCCCCCCCCEEHHHHHHHHHHHHHHHHHHH ARQFLSLMEKPDVDHIEGLSPAISIEQKSTSHNPRSTVGTITEIHDYLRLLFARVGEPRC HHHHHHHHCCCCCCHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC PDHDVPLAAQTVSQMVDNVISQPEGRRLMLLAPVVKDRKGEHTKILENLAAQGYIRARID CCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECHHHCCCCCHHHHHHHHHHCCEEEEEEC GEVCDLSDPPKLELQKKHTIEVVVDRFKVREDLAQRLAESFETALALSGGTAVVADMDDP CCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCEEEEECCCCH HVEELLFSANFACPICGYSMRELEPRLFSFNNPAGACPTCDGLGVQQFFDPDRVLQNPEL HHHHHHHHCCCCCCCCCCHHHHCCCHHEECCCCCCCCCCCCCCCHHHHCCHHHHHCCCCC SLAGGAIRGWDRRNFYYFQMLRSLAEHYKFDIEAPFNSLDSAVQQAVLYGSGKDTIEFKY EECCCCCCCCCCCCHHHHHHHHHHHHHCEEECCCCHHHHHHHHHHHHHCCCCCCEEEEEE INDRGDTTVRRHPFEGVLHNMERRYKETESSAVREELAKFISNRSCASCSGTRLRREARY ECCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCEEE VFVENTTLPEISELSIGHALSFFQNMKLSGQRAQIAEKILKEIGDRLKFLVNVGLNYLSL EEEECCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH SRSAETLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLLETLIHLRNLGNT CCCCHHCCCCCHHHHHHHHHHCCHHEEHHHEECCCCCCCCCCCHHHHHHHHHHHHCCCCE VIVVEHDEDAIRAADHVIDIGPGAGVHGGEVVAEGTVDDIMAAPASLTGQFLSGKRSIAI EEEEECCCHHHHHHHCEEECCCCCCCCCCCEEECCCHHHHHHCCHHHHHHHHCCCCCCCC PEKRVSADPSKVLKLIGATGNNLKDVTLTLPVGLFSCITGVSGSGKSTLINDTLYSIAQR CHHHCCCCHHHHHHHHCCCCCCCEEEEEEEHHHHHHHHHCCCCCCCCEEHHHHHHHHHHH QLNGATITEPAPYREIQGLEHFDKVIDIDQSPIGRTPRSNPATYTGIFTPIRELFAGVPE HCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEHHHHHHHHHHHCCCCC SRTRGYTPGRFSFNVKGGRCEACQGDGVIKVEMHFLPDIYVPCDHCKGKRYNRETLEIKY CCCCCCCCCEEEEEECCCEECCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEE KGKSIHEVLAMTIEEAREFFDAVPALARKLQTLIDVGLSYICLGQSATTLSGGEAQRVKL CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHH SRELSKRGTGQTLYILDEPTTGLHFADIQQLLAVLHQLRDQGNTIVVIEHNLDVIKTADW HHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEECCE IVDLGPEGGSGGGEILVSGTPETVAECAVSHTARFLKPMLQRKPQTV EEEECCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCC >Mature Secondary Structure MDNIEVRGARTHNLKNINLIIPRDKLIVVTGLSGSGKSSLAFDTLYAEGQRRYVESLSAY CCCCEECCCCCCCCCEEEEEECCCCEEEEECCCCCCCCCEEHHHHHHHHHHHHHHHHHHH ARQFLSLMEKPDVDHIEGLSPAISIEQKSTSHNPRSTVGTITEIHDYLRLLFARVGEPRC HHHHHHHHCCCCCCHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC PDHDVPLAAQTVSQMVDNVISQPEGRRLMLLAPVVKDRKGEHTKILENLAAQGYIRARID CCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECHHHCCCCCHHHHHHHHHHCCEEEEEEC GEVCDLSDPPKLELQKKHTIEVVVDRFKVREDLAQRLAESFETALALSGGTAVVADMDDP CCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCEEEEECCCCH HVEELLFSANFACPICGYSMRELEPRLFSFNNPAGACPTCDGLGVQQFFDPDRVLQNPEL HHHHHHHHCCCCCCCCCCHHHHCCCHHEECCCCCCCCCCCCCCCHHHHCCHHHHHCCCCC SLAGGAIRGWDRRNFYYFQMLRSLAEHYKFDIEAPFNSLDSAVQQAVLYGSGKDTIEFKY EECCCCCCCCCCCCHHHHHHHHHHHHHCEEECCCCHHHHHHHHHHHHHCCCCCCEEEEEE INDRGDTTVRRHPFEGVLHNMERRYKETESSAVREELAKFISNRSCASCSGTRLRREARY ECCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCEEE VFVENTTLPEISELSIGHALSFFQNMKLSGQRAQIAEKILKEIGDRLKFLVNVGLNYLSL EEEECCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH SRSAETLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLLETLIHLRNLGNT CCCCHHCCCCCHHHHHHHHHHCCHHEEHHHEECCCCCCCCCCCHHHHHHHHHHHHCCCCE VIVVEHDEDAIRAADHVIDIGPGAGVHGGEVVAEGTVDDIMAAPASLTGQFLSGKRSIAI EEEEECCCHHHHHHHCEEECCCCCCCCCCCEEECCCHHHHHHCCHHHHHHHHCCCCCCCC PEKRVSADPSKVLKLIGATGNNLKDVTLTLPVGLFSCITGVSGSGKSTLINDTLYSIAQR CHHHCCCCHHHHHHHHCCCCCCCEEEEEEEHHHHHHHHHCCCCCCCCEEHHHHHHHHHHH QLNGATITEPAPYREIQGLEHFDKVIDIDQSPIGRTPRSNPATYTGIFTPIRELFAGVPE HCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEHHHHHHHHHHHCCCCC SRTRGYTPGRFSFNVKGGRCEACQGDGVIKVEMHFLPDIYVPCDHCKGKRYNRETLEIKY CCCCCCCCCEEEEEECCCEECCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEE KGKSIHEVLAMTIEEAREFFDAVPALARKLQTLIDVGLSYICLGQSATTLSGGEAQRVKL CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHH SRELSKRGTGQTLYILDEPTTGLHFADIQQLLAVLHQLRDQGNTIVVIEHNLDVIKTADW HHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEECCE IVDLGPEGGSGGGEILVSGTPETVAECAVSHTARFLKPMLQRKPQTV EEEECCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: DNA [C]
Specific reaction: Protein + DNA = Protein-DNA [C]
General reaction: Hydrolase; Acting on ester bonds [C]
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 11586360; 12142430 [H]