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The map label for this gene is dnaA [H]

Identifier: 153950668

GI number: 153950668

Start: 4688891

End: 4690279

Strand: Reverse

Name: dnaA [H]

Synonym: YpsIP31758_4153

Alternate gene names: 153950668

Gene position: 4690279-4688891 (Counterclockwise)

Preceding gene: 153950352

Following gene: 153950603

Centisome position: 99.3

GC content: 47.66

Gene sequence:

>1389_bases
GTGTCACTTTCGCTTTGGCAGCAGTGTCTTGCCCGATTGCAGGATGAGTTACCTGCCACAGAATTTAGTATGTGGATACG
CCCCCTACAGGCGGAACTGAGTGACAATACTCTGGCGCTTTACGCACCTAATCGTTTTGTACTGGACTGGGTCCGTGATA
AGTACTTAAACAATATCAATGGCTTACTTAATGATTTTTGTGGCACCGAGGTCCCTTTACTGCGTTTTGAGGTAGGGAGT
AAACCTGCGGCAAGAGCACACAATAATCCAGTTACAGCCAGCGTGAGTGCGCCTGTTGCTCCGGTTACCCGCAGTGCACC
TATGCGCCCGAGCTGGGACAACTCACCTGCTCAGCCTGAACTTTCTTATCGTTCGAATGTGAATCCAAAACACACATTTG
ATAACTTTGTTGAAGGTAAATCTAACCAGTTGGCCCGCGCTGCCGCCCGTCAGGTAGCCGATAACCCAGGTGGTGCCTAT
AACCCGTTATTTCTTTATGGCGGAACAGGCTTGGGTAAAACCCATCTGCTACACGCGGTGGGGAATGGCATTATGGCCCG
TAAAGCCAATGCTAAAGTGGTCTATATGCATTCCGAGCGTTTTGTGCAAGATATGGTCAAAGCCTTGCAAAATAATGCTA
TCGAAGAGTTTAAACGCTATTATCGTTCGGTTGATGCTTTATTAATCGATGATATTCAATTTTTTGCCAATAAAGAGCGT
TCTCAAGAAGAGTTTTTCCACACCTTTAATGCGTTGCTAGAGGGTAATCAGCAGATCATTTTGACCTCAGATCGCTATCC
AAAAGAGATTAACGGGGTGGAAGATCGTCTGAAGTCGCGTTTTGGTTGGGGGCTGACGGTCGCCATTGAGCCACCAGAGC
TGGAAACGCGTGTAGCGATCCTAATGAAGAAAGCGGATGAAAATGATATTCGCTTACCAGGAGAGGTCGCGTTCTTTATT
GCCAAGCGTCTGCGTTCCAATGTGCGTGAATTGGAAGGGGCATTGAACCGTGTGATCGCCAATGCCAATTTTACTGGCCG
CGCTATCACGATTGATTTTGTTCGCGAAGCCCTGCGTGATTTGTTGGCGTTGCAAGAAAAGCTGGTCACTATCGATAATA
TTCAAAAGACTGTTGCTGAATATTATAAAATTAAGGTCGCTGACCTGCTCTCCAAACGGCGTTCTCGTTCGGTTGCCCGC
CCTCGCCAAATGGCTATGGCATTGGCAAAAGAGCTAACCAACCACAGCCTGCCTGAAATCGGCGATGCGTTTGGTGGCCG
CGACCATACCACGGTGTTGCACGCTTGCCGGAAGATTGAGCAATTGCGTGAGGAAAGTCACGACATCAAAGAAGATTTCT
CTAACTTAATCAGAACATTATCCTCCTAG

Upstream 100 bases:

>100_bases
ACCTTGGCTTGCTACAGGCCATATGGCGTGTGTCAAAACGATGAGTTACAAAATATCCTGATTTCTTTCTTTTATTGATC
TTGTTCGAGTGGAGTCCGCC

Downstream 100 bases:

>100_bases
CGCTATGAAATTTATCATTGAACGTGAGCATCTGCTAAAACCACTGCAACAGGTCAGTAGCCCGCTGGGTGGACGCCCTA
CGTTGCCTATTTTGGGTAAC

Product: chromosomal replication initiation protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 462; Mature: 461

Protein sequence:

>462_residues
MSLSLWQQCLARLQDELPATEFSMWIRPLQAELSDNTLALYAPNRFVLDWVRDKYLNNINGLLNDFCGTEVPLLRFEVGS
KPAARAHNNPVTASVSAPVAPVTRSAPMRPSWDNSPAQPELSYRSNVNPKHTFDNFVEGKSNQLARAAARQVADNPGGAY
NPLFLYGGTGLGKTHLLHAVGNGIMARKANAKVVYMHSERFVQDMVKALQNNAIEEFKRYYRSVDALLIDDIQFFANKER
SQEEFFHTFNALLEGNQQIILTSDRYPKEINGVEDRLKSRFGWGLTVAIEPPELETRVAILMKKADENDIRLPGEVAFFI
AKRLRSNVRELEGALNRVIANANFTGRAITIDFVREALRDLLALQEKLVTIDNIQKTVAEYYKIKVADLLSKRRSRSVAR
PRQMAMALAKELTNHSLPEIGDAFGGRDHTTVLHACRKIEQLREESHDIKEDFSNLIRTLSS

Sequences:

>Translated_462_residues
MSLSLWQQCLARLQDELPATEFSMWIRPLQAELSDNTLALYAPNRFVLDWVRDKYLNNINGLLNDFCGTEVPLLRFEVGS
KPAARAHNNPVTASVSAPVAPVTRSAPMRPSWDNSPAQPELSYRSNVNPKHTFDNFVEGKSNQLARAAARQVADNPGGAY
NPLFLYGGTGLGKTHLLHAVGNGIMARKANAKVVYMHSERFVQDMVKALQNNAIEEFKRYYRSVDALLIDDIQFFANKER
SQEEFFHTFNALLEGNQQIILTSDRYPKEINGVEDRLKSRFGWGLTVAIEPPELETRVAILMKKADENDIRLPGEVAFFI
AKRLRSNVRELEGALNRVIANANFTGRAITIDFVREALRDLLALQEKLVTIDNIQKTVAEYYKIKVADLLSKRRSRSVAR
PRQMAMALAKELTNHSLPEIGDAFGGRDHTTVLHACRKIEQLREESHDIKEDFSNLIRTLSS
>Mature_461_residues
SLSLWQQCLARLQDELPATEFSMWIRPLQAELSDNTLALYAPNRFVLDWVRDKYLNNINGLLNDFCGTEVPLLRFEVGSK
PAARAHNNPVTASVSAPVAPVTRSAPMRPSWDNSPAQPELSYRSNVNPKHTFDNFVEGKSNQLARAAARQVADNPGGAYN
PLFLYGGTGLGKTHLLHAVGNGIMARKANAKVVYMHSERFVQDMVKALQNNAIEEFKRYYRSVDALLIDDIQFFANKERS
QEEFFHTFNALLEGNQQIILTSDRYPKEINGVEDRLKSRFGWGLTVAIEPPELETRVAILMKKADENDIRLPGEVAFFIA
KRLRSNVRELEGALNRVIANANFTGRAITIDFVREALRDLLALQEKLVTIDNIQKTVAEYYKIKVADLLSKRRSRSVARP
RQMAMALAKELTNHSLPEIGDAFGGRDHTTVLHACRKIEQLREESHDIKEDFSNLIRTLSS

Specific function: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box):5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phosph

COG id: COG0593

COG function: function code L; ATPase involved in DNA replication initiation

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dnaA family [H]

Homologues:

Organism=Escherichia coli, GI2367267, Length=468, Percent_Identity=91.8803418803419, Blast_Score=874, Evalue=0.0,
Organism=Escherichia coli, GI226510964, Length=249, Percent_Identity=28.1124497991968, Blast_Score=85, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001957
- InterPro:   IPR020591
- InterPro:   IPR018312
- InterPro:   IPR013159
- InterPro:   IPR013317
- InterPro:   IPR010921 [H]

Pfam domain/function: PF00308 Bac_DnaA; PF08299 Bac_DnaA_C [H]

EC number: NA

Molecular weight: Translated: 52177; Mature: 52046

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: PS01008 DNAA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLSLWQQCLARLQDELPATEFSMWIRPLQAELSDNTLALYAPNRFVLDWVRDKYLNNIN
CCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHH
GLLNDFCGTEVPLLRFEVGSKPAARAHNNPVTASVSAPVAPVTRSAPMRPSWDNSPAQPE
HHHHHHCCCCCCEEEEECCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCC
LSYRSNVNPKHTFDNFVEGKSNQLARAAARQVADNPGGAYNPLFLYGGTGLGKTHLLHAV
CCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCHHHHHHHH
GNGIMARKANAKVVYMHSERFVQDMVKALQNNAIEEFKRYYRSVDALLIDDIQFFANKER
CCCCEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SQEEFFHTFNALLEGNQQIILTSDRYPKEINGVEDRLKSRFGWGLTVAIEPPELETRVAI
HHHHHHHHHHHHHCCCCEEEEECCCCCHHCCCHHHHHHHHCCCCEEEEECCCCHHHHHHH
LMKKADENDIRLPGEVAFFIAKRLRSNVRELEGALNRVIANANFTGRAITIDFVREALRD
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHH
LLALQEKLVTIDNIQKTVAEYYKIKVADLLSKRRSRSVARPRQMAMALAKELTNHSLPEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCHH
GDAFGGRDHTTVLHACRKIEQLREESHDIKEDFSNLIRTLSS
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SLSLWQQCLARLQDELPATEFSMWIRPLQAELSDNTLALYAPNRFVLDWVRDKYLNNIN
CHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHH
GLLNDFCGTEVPLLRFEVGSKPAARAHNNPVTASVSAPVAPVTRSAPMRPSWDNSPAQPE
HHHHHHCCCCCCEEEEECCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCC
LSYRSNVNPKHTFDNFVEGKSNQLARAAARQVADNPGGAYNPLFLYGGTGLGKTHLLHAV
CCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCHHHHHHHH
GNGIMARKANAKVVYMHSERFVQDMVKALQNNAIEEFKRYYRSVDALLIDDIQFFANKER
CCCCEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SQEEFFHTFNALLEGNQQIILTSDRYPKEINGVEDRLKSRFGWGLTVAIEPPELETRVAI
HHHHHHHHHHHHHCCCCEEEEECCCCCHHCCCHHHHHHHHCCCCEEEEECCCCHHHHHHH
LMKKADENDIRLPGEVAFFIAKRLRSNVRELEGALNRVIANANFTGRAITIDFVREALRD
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHH
LLALQEKLVTIDNIQKTVAEYYKIKVADLLSKRRSRSVARPRQMAMALAKELTNHSLPEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCHH
GDAFGGRDHTTVLHACRKIEQLREESHDIKEDFSNLIRTLSS
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA