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The map label for this gene is chbR [H]

Identifier: 153950456

GI number: 153950456

Start: 1296765

End: 1297595

Strand: Direct

Name: chbR [H]

Synonym: YpsIP31758_1094

Alternate gene names: 153950456

Gene position: 1296765-1297595 (Clockwise)

Preceding gene: 153948067

Following gene: 153950115

Centisome position: 27.45

GC content: 40.79

Gene sequence:

>831_bases
ATGGACGTCAGATTAGTACGTGAAAGAGACTTTTTTAACGGTAAAGAATTCCATCTGTTTATTTACAACAAAACGGAGAG
TGCGACCGGTTTACATCAGCATGATTATTATGAATATACGCTGATATTAACCGGGATGTGCTACCAGGAAATTAACGGAA
AGCGTGTTTTTTTGGAGCGTGGGGACTTTATCTTTATTCCTCTTGGTTCTCATCATCAAAGTTTCTATGAGTTTGGTGCC
ACCCGGATCCTGAATGTCGGGATCAGTAAAGCTTTCTTTGAAGAACATTATTTCCATTTACTGTCTCGGCCTATTGTGGC
CTCTCAGGCGTATCGCTTAAGAGGTGATTTTCTTTCCTATATCGAATCGGCGATCTCTGCTCCACACTACAGAGAAAATG
AGCAAACAGAACTTTTAGAGCTACTGACTTTTTATGTGACTAACCGCATCAGTCATTACAAAGAGAGTGAAGTTAACGAC
GATATACCTTCGTGGCTGAAGGCCACAATCGACAAAATGCATGATAACGCGATGTTTAGTGAGAAGGCGTTGGTGAATAT
GGTCGAGCTTTCTGGCAAAACCCAAGAATATCTCACCAGAGCGACACGGCGCTATTATCAGAAAACGCCCATGCAGATTA
TCAATGAAATTAGAATAAATTTTGCCAAAACCCAACTTGAAGTGACGAACTATTTAGTTTCGGATATTGCATTTGAAGCA
GGCTACAGCGACACCACGTTATTCATCAAAAACTTCAAAAAATTAACCTCTTTTACGCCAGGAAACTATCGCAAGAACTT
CTACAGCGCCAGAGAGAGTTTATCCCATTAG

Upstream 100 bases:

>100_bases
AGCGCGAGAATTGATTACTGAGCTTATCGAGTTGCATCAAAAAATTCAGTGATACGCCGACGGGGCGATAATTCTCAATG
GTAGAGCGATGGTGACTAAG

Downstream 100 bases:

>100_bases
TTTTCCAACCGGTTATTCCCATAGTGGGAGAGGGTTGGCAAGGAACCTTTAATGGAAAAATTACTTATTGTTAATGCCGA
TGATTTTGGTCTGTGTAAAG

Product: DNA-binding transcriptional regulator ChbR

Products: NA

Alternate protein names: Chb operon repressor [H]

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MDVRLVRERDFFNGKEFHLFIYNKTESATGLHQHDYYEYTLILTGMCYQEINGKRVFLERGDFIFIPLGSHHQSFYEFGA
TRILNVGISKAFFEEHYFHLLSRPIVASQAYRLRGDFLSYIESAISAPHYRENEQTELLELLTFYVTNRISHYKESEVND
DIPSWLKATIDKMHDNAMFSEKALVNMVELSGKTQEYLTRATRRYYQKTPMQIINEIRINFAKTQLEVTNYLVSDIAFEA
GYSDTTLFIKNFKKLTSFTPGNYRKNFYSARESLSH

Sequences:

>Translated_276_residues
MDVRLVRERDFFNGKEFHLFIYNKTESATGLHQHDYYEYTLILTGMCYQEINGKRVFLERGDFIFIPLGSHHQSFYEFGA
TRILNVGISKAFFEEHYFHLLSRPIVASQAYRLRGDFLSYIESAISAPHYRENEQTELLELLTFYVTNRISHYKESEVND
DIPSWLKATIDKMHDNAMFSEKALVNMVELSGKTQEYLTRATRRYYQKTPMQIINEIRINFAKTQLEVTNYLVSDIAFEA
GYSDTTLFIKNFKKLTSFTPGNYRKNFYSARESLSH
>Mature_276_residues
MDVRLVRERDFFNGKEFHLFIYNKTESATGLHQHDYYEYTLILTGMCYQEINGKRVFLERGDFIFIPLGSHHQSFYEFGA
TRILNVGISKAFFEEHYFHLLSRPIVASQAYRLRGDFLSYIESAISAPHYRENEQTELLELLTFYVTNRISHYKESEVND
DIPSWLKATIDKMHDNAMFSEKALVNMVELSGKTQEYLTRATRRYYQKTPMQIINEIRINFAKTQLEVTNYLVSDIAFEA
GYSDTTLFIKNFKKLTSFTPGNYRKNFYSARESLSH

Specific function: Dual-function repressor/activator of the chbBCARFG operon. In the absence of the inducing sugar chitobiose, together with NagC, represses the chbBCARFG operon for the uptake and metabolism of chitobiose. In association with Crp, and probably in the presen

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788030, Length=264, Percent_Identity=69.6969696969697, Blast_Score=392, Evalue=1e-110,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013096
- InterPro:   IPR011051
- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018062
- InterPro:   IPR020449
- InterPro:   IPR018060
- InterPro:   IPR014710 [H]

Pfam domain/function: PF07883 Cupin_2; PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 32538; Mature: 32538

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVRLVRERDFFNGKEFHLFIYNKTESATGLHQHDYYEYTLILTGMCYQEINGKRVFLER
CCCEEEECCCCCCCCEEEEEEEECCCCCCCCCCCCCEEEEHEEHHHHHHHCCCCEEEEEC
GDFIFIPLGSHHQSFYEFGATRILNVGISKAFFEEHYFHLLSRPIVASQAYRLRGDFLSY
CCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
IESAISAPHYRENEQTELLELLTFYVTNRISHYKESEVNDDIPSWLKATIDKMHDNAMFS
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
EKALVNMVELSGKTQEYLTRATRRYYQKTPMQIINEIRINFAKTQLEVTNYLVSDIAFEA
HHHHHHHHHHCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GYSDTTLFIKNFKKLTSFTPGNYRKNFYSARESLSH
CCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MDVRLVRERDFFNGKEFHLFIYNKTESATGLHQHDYYEYTLILTGMCYQEINGKRVFLER
CCCEEEECCCCCCCCEEEEEEEECCCCCCCCCCCCCEEEEHEEHHHHHHHCCCCEEEEEC
GDFIFIPLGSHHQSFYEFGATRILNVGISKAFFEEHYFHLLSRPIVASQAYRLRGDFLSY
CCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
IESAISAPHYRENEQTELLELLTFYVTNRISHYKESEVNDDIPSWLKATIDKMHDNAMFS
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
EKALVNMVELSGKTQEYLTRATRRYYQKTPMQIINEIRINFAKTQLEVTNYLVSDIAFEA
HHHHHHHHHHCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GYSDTTLFIKNFKKLTSFTPGNYRKNFYSARESLSH
CCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2179047; 9097039; 9278503; 9405618 [H]