Click here to switch to the map view.

The map label for this gene is ail [H]

Identifier: 153950193

GI number: 153950193

Start: 2562619

End: 2563170

Strand: Reverse

Name: ail [H]

Synonym: YpsIP31758_2257

Alternate gene names: 153950193

Gene position: 2563170-2562619 (Counterclockwise)

Preceding gene: 153949724

Following gene: 153950821

Centisome position: 54.27

GC content: 37.5

Gene sequence:

>552_bases
ATGAAAAATAAAACCACATTGGCTGCATTTATAACAGCGACCTTATTAAGCAGTTCAGCGGCCTATGCGGCAGGGGATCG
TACCATCTCATTGGGGTATGCTCAGGGAGATGTAAGACTCGGTGATGGAAATCGAAAAGACATTAGATTGGATGATGATC
TTAAAGGAATTAATGTTAAATACCTCCATAAGTTGAGTGAAATGTTCGGTGCAATAGGCTCTTTTACTTACACGGATTTA
AATTATGATTATCTAAATAATAATGTCAAAATTGGGGATGCATCCTTTGATTATTATTCGCTGATGGTTGGGCCAAGCGT
ACATTTTAATGAGTTTTTCAGCATGTATGCATTGTTGGGAATTGGGCATGGGAAAGCGAAAGCATCTGTATTAGGTTACG
GTAAAAAAGAGGAGCAAGACTCTTTGGCATATGGTGTTGGGATGCAATTTAATCCACTTAACAATATTGCTATTGATGCT
TCATACGAGTATGCAAAACTTAAAAATGCTAATATTGGCACATGGGTTTTAGGCATTGGCTATCGTTTTTAA

Upstream 100 bases:

>100_bases
ACACATGGAATTTTGTGTTTGCGATGGACGACTGGCTGAATATTAGTGACCAATGCGACGATACCGTAATCTAAGATAAT
AATTTAAGGATAAAAGTTTA

Downstream 100 bases:

>100_bases
TAAAATACTTTCTATATAATAATAACAGCCGTATTAGTTCACTGTGCGGCTGTTTTTTTCATCAGTTGCAAAGAGATTCA
TAACGATAAAAAATTGAGTC

Product: Ail/Lom family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 183; Mature: 183

Protein sequence:

>183_residues
MKNKTTLAAFITATLLSSSAAYAAGDRTISLGYAQGDVRLGDGNRKDIRLDDDLKGINVKYLHKLSEMFGAIGSFTYTDL
NYDYLNNNVKIGDASFDYYSLMVGPSVHFNEFFSMYALLGIGHGKAKASVLGYGKKEEQDSLAYGVGMQFNPLNNIAIDA
SYEYAKLKNANIGTWVLGIGYRF

Sequences:

>Translated_183_residues
MKNKTTLAAFITATLLSSSAAYAAGDRTISLGYAQGDVRLGDGNRKDIRLDDDLKGINVKYLHKLSEMFGAIGSFTYTDL
NYDYLNNNVKIGDASFDYYSLMVGPSVHFNEFFSMYALLGIGHGKAKASVLGYGKKEEQDSLAYGVGMQFNPLNNIAIDA
SYEYAKLKNANIGTWVLGIGYRF
>Mature_183_residues
MKNKTTLAAFITATLLSSSAAYAAGDRTISLGYAQGDVRLGDGNRKDIRLDDDLKGINVKYLHKLSEMFGAIGSFTYTDL
NYDYLNNNVKIGDASFDYYSLMVGPSVHFNEFFSMYALLGIGHGKAKASVLGYGKKEEQDSLAYGVGMQFNPLNNIAIDA
SYEYAKLKNANIGTWVLGIGYRF

Specific function: Promotes the invasion of pathogenic bacteria into eukaryotic cells by an unknown mechanism [H]

COG id: COG3637

COG function: function code M; Opacity protein and related surface antigens

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ail/ompX/pagC/lom family [H]

Homologues:

Organism=Escherichia coli, GI1787034, Length=190, Percent_Identity=33.6842105263158, Blast_Score=104, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000758
- InterPro:   IPR011250 [H]

Pfam domain/function: PF06316 Ail_Lom [H]

EC number: NA

Molecular weight: Translated: 20081; Mature: 20081

Theoretical pI: Translated: 7.71; Mature: 7.71

Prosite motif: PS00695 ENT_VIR_OMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNKTTLAAFITATLLSSSAAYAAGDRTISLGYAQGDVRLGDGNRKDIRLDDDLKGINVK
CCCCHHHHHHHHHHHHHCCCCEECCCEEEEEEEECCCEEECCCCCCCEEECCCCCCCCHH
YLHKLSEMFGAIGSFTYTDLNYDYLNNNVKIGDASFDYYSLMVGPSVHFNEFFSMYALLG
HHHHHHHHHHHHCCEEEECCCHHHCCCEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHH
IGHGKAKASVLGYGKKEEQDSLAYGVGMQFNPLNNIAIDASYEYAKLKNANIGTWVLGIG
CCCCCCEEEEECCCCCCCCCCEEEECCCEECCCCCEEEECCCCEEEECCCCCCEEEEEEC
YRF
CCC
>Mature Secondary Structure
MKNKTTLAAFITATLLSSSAAYAAGDRTISLGYAQGDVRLGDGNRKDIRLDDDLKGINVK
CCCCHHHHHHHHHHHHHCCCCEECCCEEEEEEEECCCEEECCCCCCCEEECCCCCCCCHH
YLHKLSEMFGAIGSFTYTDLNYDYLNNNVKIGDASFDYYSLMVGPSVHFNEFFSMYALLG
HHHHHHHHHHHHCCEEEECCCHHHCCCEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHH
IGHGKAKASVLGYGKKEEQDSLAYGVGMQFNPLNNIAIDASYEYAKLKNANIGTWVLGIG
CCCCCCEEEEECCCCCCCCCCEEEECCCEECCCCCEEEECCCCEEEECCCCCCEEEEEEC
YRF
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1688838 [H]