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The map label for this gene is lpxH

Identifier: 153950149

GI number: 153950149

Start: 3394959

End: 3395681

Strand: Direct

Name: lpxH

Synonym: YpsIP31758_3016

Alternate gene names: 153950149

Gene position: 3394959-3395681 (Clockwise)

Preceding gene: 153946872

Following gene: 153947779

Centisome position: 71.88

GC content: 47.3

Gene sequence:

>723_bases
ATGAGCACGCTTTTTATTGCAGATCTGCATCTCAGCGTTCAGGAACCGGCAATCACTGCCGGTTTTCTGCATTTTATACA
GCGTGAGGCTATTCATGCTGATGCTTTATATATTCTGGGCGATCTGTTCGAATCCTGGATTGGTGATGACGACCCCGAGC
CACTGTATCGGCAGGTTGCTGCTGCGCTGAAATCACTCCAACAACAGGGGGTGCCCTGTTATTTTATCCACGGGAACCGC
GATTTTCTGCTCGGTAAACGTTTTGCTGAAGAAAGCGGCATGGTCTTGCTGCCGGAAGAGAACGTTGTTGAATTATATGG
CCGTAAAATCCTTATTTTACATGGCGATACTCTGTGTACGGATGATACCGATTACCAGCATTTTCGTAAAAAGGTCCATA
ATCCGCTGATTCAAAAATTATTTTTGTGGATCCCTCTGCGCCTGCGTCTGCGTATTGCGGCCTATATGCGGAATAAGAGC
CAGCAGAATAATAGCGGTAAATCAGAACACATTATGGATGTGAATTCAAAAGCGGTAATTGATGCTTTCCTGCGCCATGA
CGTCAGTTGGATGATCCATGGGCATACGCACCGGCCAGCCATCCATAGCGTAGAATTGCCGATGGTAACAGCACATCGGG
TGGTGCTGGGGGCCTGGCATGTCGAAGGTTCAATGGTCAAAGTTACGGCAGATAACGTCGAGCTAATTACATTCCCGTTT
TAA

Upstream 100 bases:

>100_bases
ATCAAAAATGTTGCGACGGGCCGCAGTGGCATGCATCAAGATGTGCCAAAAGAAGATGTGATCATCAAAAGCGTCACTAT
TAGCGAGTAATGACGGCTTA

Downstream 100 bases:

>100_bases
CATCCATTTCTACGCAATAACCTCGATCACCACACAGTAACCACGATTACCACGCGATAACCTTGATTACCAAGCAATCA
CCCGCTCATGACGAATAACA

Product: UDP-2,3-diacylglucosamine hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 239

Protein sequence:

>240_residues
MSTLFIADLHLSVQEPAITAGFLHFIQREAIHADALYILGDLFESWIGDDDPEPLYRQVAAALKSLQQQGVPCYFIHGNR
DFLLGKRFAEESGMVLLPEENVVELYGRKILILHGDTLCTDDTDYQHFRKKVHNPLIQKLFLWIPLRLRLRIAAYMRNKS
QQNNSGKSEHIMDVNSKAVIDAFLRHDVSWMIHGHTHRPAIHSVELPMVTAHRVVLGAWHVEGSMVKVTADNVELITFPF

Sequences:

>Translated_240_residues
MSTLFIADLHLSVQEPAITAGFLHFIQREAIHADALYILGDLFESWIGDDDPEPLYRQVAAALKSLQQQGVPCYFIHGNR
DFLLGKRFAEESGMVLLPEENVVELYGRKILILHGDTLCTDDTDYQHFRKKVHNPLIQKLFLWIPLRLRLRIAAYMRNKS
QQNNSGKSEHIMDVNSKAVIDAFLRHDVSWMIHGHTHRPAIHSVELPMVTAHRVVLGAWHVEGSMVKVTADNVELITFPF
>Mature_239_residues
STLFIADLHLSVQEPAITAGFLHFIQREAIHADALYILGDLFESWIGDDDPEPLYRQVAAALKSLQQQGVPCYFIHGNRD
FLLGKRFAEESGMVLLPEENVVELYGRKILILHGDTLCTDDTDYQHFRKKVHNPLIQKLFLWIPLRLRLRIAAYMRNKSQ
QNNSGKSEHIMDVNSKAVIDAFLRHDVSWMIHGHTHRPAIHSVELPMVTAHRVVLGAWHVEGSMVKVTADNVELITFPF

Specific function: Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP

COG id: COG2908

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lpxH family

Homologues:

Organism=Escherichia coli, GI1786735, Length=240, Percent_Identity=70, Blast_Score=354, Evalue=3e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LPXH_YERP3 (A7FL48)

Other databases:

- EMBL:   CP000720
- RefSeq:   YP_001401976.1
- ProteinModelPortal:   A7FL48
- SMR:   A7FL48
- STRING:   A7FL48
- GeneID:   5384956
- GenomeReviews:   CP000720_GR
- KEGG:   ypi:YpsIP31758_3016
- NMPDR:   fig|349747.3.peg.3691
- eggNOG:   COG2908
- HOGENOM:   HBG288883
- OMA:   CHGDTLC
- ProtClustDB:   PRK05340
- BioCyc:   YPSE349747:YPSIP31758_3016-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00575
- InterPro:   IPR004843
- InterPro:   IPR010138
- TIGRFAMs:   TIGR01854

Pfam domain/function: PF00149 Metallophos

EC number: 3.6.1.-

Molecular weight: Translated: 27425; Mature: 27294

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTLFIADLHLSVQEPAITAGFLHFIQREAIHADALYILGDLFESWIGDDDPEPLYRQVA
CCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
AALKSLQQQGVPCYFIHGNRDFLLGKRFAEESGMVLLPEENVVELYGRKILILHGDTLCT
HHHHHHHHCCCCEEEEECCCCEEHHHHHHCCCCEEEECCCCHHHHCCCEEEEEECCEEEC
DDTDYQHFRKKVHNPLIQKLFLWIPLRLRLRIAAYMRNKSQQNNSGKSEHIMDVNSKAVI
CCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCHHHH
DAFLRHDVSWMIHGHTHRPAIHSVELPMVTAHRVVLGAWHVEGSMVKVTADNVELITFPF
HHHHHCCCEEEEECCCCCCCCEEECCCHHHHHEEEEEEEEECCCEEEEEECCEEEEEECC
>Mature Secondary Structure 
STLFIADLHLSVQEPAITAGFLHFIQREAIHADALYILGDLFESWIGDDDPEPLYRQVA
CEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
AALKSLQQQGVPCYFIHGNRDFLLGKRFAEESGMVLLPEENVVELYGRKILILHGDTLCT
HHHHHHHHCCCCEEEEECCCCEEHHHHHHCCCCEEEECCCCHHHHCCCEEEEEECCEEEC
DDTDYQHFRKKVHNPLIQKLFLWIPLRLRLRIAAYMRNKSQQNNSGKSEHIMDVNSKAVI
CCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCHHHH
DAFLRHDVSWMIHGHTHRPAIHSVELPMVTAHRVVLGAWHVEGSMVKVTADNVELITFPF
HHHHHCCCEEEEECCCCCCCCEEECCCHHHHHEEEEEEEEECCCEEEEEECCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA