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The map label for this gene is ygfA [H]

Identifier: 153950067

GI number: 153950067

Start: 1036479

End: 1037075

Strand: Reverse

Name: ygfA [H]

Synonym: YpsIP31758_0857

Alternate gene names: 153950067

Gene position: 1037075-1036479 (Counterclockwise)

Preceding gene: 153947012

Following gene: 153948807

Centisome position: 21.96

GC content: 51.93

Gene sequence:

>597_bases
ATGCCGCAAAATCCACAACATGCCCTTGAGCGGCAACGTATCCGCGCGGAAATCCGTGAGCATCGGCGTCTGCTAACACC
CGTTCAACAGCAACAATCGGCACATCTGGCGGCACAGCACATTGCCGAGCACCCCAAAATCCAGCAAGCTCACACGGTAG
CCGTGTTTCTCTCCTTTGACGGCGAACTTGATACCCAGCCAATTATTGAGCAACTGTGGCAGCAGAAAAAACAGGTTTAT
TTGCCTGTCCTCCACCCGTTTAGCCCCGGTAATTTATTATTTCTGCGCTATCGCCCAGAAAGCCCGCTAACCCGCAACCG
ACTGAAAATCCTTGAACCCCAACTCGATGTGCGAGAAGTCTTGCCATTGCATCAACTCGATGTAGTGATTACCCCATTGG
TCGCCTTTGATCGCCATGGTCAGCGTTTGGGGATGGGGGGCGGTTTTTATGACCGAACTCTGCAACGCTGGCAGCAAAAT
GGCCCTTATCCTATTGGATTGGCCCATGATTGCCAGTTGGTCGATAAGTTACCGAGTGAATATTGGGATGTGCCGTTGCC
AGAGATTGTGACACCAGCAAAAGTGTGGCAGTGGTGA

Upstream 100 bases:

>100_bases
GATGATCAACAGTATTGATATCCAAAAGTAGCGATGTTCAAAAGTAGCGTTAATCAATACTCTTTGGGTTATCGACTATA
TCCTGATACAGGCAGTTTTT

Downstream 100 bases:

>100_bases
AAGAAAATCGTTCGAGATAAAAAAAACACCGGGGATCCTATGGATCCCCGGTGTCAGACTGCTGACAAACCCCGATGACT
CACTCTTGAACGGTGAGGAT

Product: 5,10-methenyltetrahydrofolate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 198; Mature: 197

Protein sequence:

>198_residues
MPQNPQHALERQRIRAEIREHRRLLTPVQQQQSAHLAAQHIAEHPKIQQAHTVAVFLSFDGELDTQPIIEQLWQQKKQVY
LPVLHPFSPGNLLFLRYRPESPLTRNRLKILEPQLDVREVLPLHQLDVVITPLVAFDRHGQRLGMGGGFYDRTLQRWQQN
GPYPIGLAHDCQLVDKLPSEYWDVPLPEIVTPAKVWQW

Sequences:

>Translated_198_residues
MPQNPQHALERQRIRAEIREHRRLLTPVQQQQSAHLAAQHIAEHPKIQQAHTVAVFLSFDGELDTQPIIEQLWQQKKQVY
LPVLHPFSPGNLLFLRYRPESPLTRNRLKILEPQLDVREVLPLHQLDVVITPLVAFDRHGQRLGMGGGFYDRTLQRWQQN
GPYPIGLAHDCQLVDKLPSEYWDVPLPEIVTPAKVWQW
>Mature_197_residues
PQNPQHALERQRIRAEIREHRRLLTPVQQQQSAHLAAQHIAEHPKIQQAHTVAVFLSFDGELDTQPIIEQLWQQKKQVYL
PVLHPFSPGNLLFLRYRPESPLTRNRLKILEPQLDVREVLPLHQLDVVITPLVAFDRHGQRLGMGGGFYDRTLQRWQQNG
PYPIGLAHDCQLVDKLPSEYWDVPLPEIVTPAKVWQW

Specific function: Unknown

COG id: COG0212

COG function: function code H; 5-formyltetrahydrofolate cyclo-ligase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family [H]

Homologues:

Organism=Homo sapiens, GI5453746, Length=188, Percent_Identity=28.7234042553192, Blast_Score=88, Evalue=5e-18,
Organism=Escherichia coli, GI1789278, Length=181, Percent_Identity=69.6132596685083, Blast_Score=263, Evalue=6e-72,
Organism=Caenorhabditis elegans, GI17510857, Length=194, Percent_Identity=26.2886597938144, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002698 [H]

Pfam domain/function: PF01812 5-FTHF_cyc-lig [H]

EC number: NA

Molecular weight: Translated: 23102; Mature: 22971

Theoretical pI: Translated: 8.50; Mature: 8.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQNPQHALERQRIRAEIREHRRLLTPVQQQQSAHLAAQHIAEHPKIQQAHTVAVFLSFD
CCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEC
GELDTQPIIEQLWQQKKQVYLPVLHPFSPGNLLFLRYRPESPLTRNRLKILEPQLDVREV
CCCCCHHHHHHHHHHHHHEECEEECCCCCCCEEEEEECCCCCCCCCHHHHCCCCCCHHHH
LPLHQLDVVITPLVAFDRHGQRLGMGGGFYDRTLQRWQQNGPYPIGLAHDCQLVDKLPSE
CCHHHHHHHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHCCCEEECCCHHHHHHHHCCHH
YWDVPLPEIVTPAKVWQW
HCCCCCHHHCCCHHHCCC
>Mature Secondary Structure 
PQNPQHALERQRIRAEIREHRRLLTPVQQQQSAHLAAQHIAEHPKIQQAHTVAVFLSFD
CCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEC
GELDTQPIIEQLWQQKKQVYLPVLHPFSPGNLLFLRYRPESPLTRNRLKILEPQLDVREV
CCCCCHHHHHHHHHHHHHEECEEECCCCCCCEEEEEECCCCCCCCCHHHHCCCCCCHHHH
LPLHQLDVVITPLVAFDRHGQRLGMGGGFYDRTLQRWQQNGPYPIGLAHDCQLVDKLPSE
CCHHHHHHHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHCCCEEECCCHHHHHHHHCCHH
YWDVPLPEIVTPAKVWQW
HCCCCCHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]