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The map label for this gene is avtA [H]

Identifier: 153950052

GI number: 153950052

Start: 4674286

End: 4675551

Strand: Direct

Name: avtA [H]

Synonym: YpsIP31758_4140

Alternate gene names: 153950052

Gene position: 4674286-4675551 (Clockwise)

Preceding gene: 153947099

Following gene: 153947928

Centisome position: 98.96

GC content: 48.82

Gene sequence:

>1266_bases
ATGAAGTTTTCACTTTTCGGCGACAAATTTACCCGTTATGCGGGTATTACCAGATTGATGGATGACCTCAACGATGGCCT
GAGAACACCGGGTTCTATCATGCTTGGTGGCGGAAATCCGGCACATATCCCTGAGATGGATACCTACTTCCAACAACTGT
GTCAGGAGATGCTAACAGAAGGCAAGTTAACCGAGGCATTGTGTAATTACGACGGGCCGCAAGGTAAAGACTTACTGCTA
AACGCACTGGCAAAAATGCTGCGCGATGAGCTGGGTTGGCAGATAGAACCACAGAATATTGCACTGACAAATGGCAGTCA
GAGTGCATTTTTCTACTTATTTAATTTGTTCGCTGGCCGTTATGCCGATGGTAGCCGCCATCGGGTGCTGTTCCCACTGG
CGCCAGAGTATCTGGGCTATGCGGATGCAGGTCTGGATGAAGATTTATTTGTCTCCGCCAAACCGAATATTGAGCTGTTA
CCCGAGGGGCAGTTTAAATATCACGTGGATTTTGAACACCTCAATATTACTGATGATATTGGCTTGATATGCGTATCAAG
GCCTACAAACCCCACCGGTAATGTCATTACTGACGAAGAGTTAATCCGCCTTGATGCGATCGCGCAGCAACGTAATATTC
CGTTATTGATTGATAATGCTTATGGCGTCCCCTTCCCTGGTATTATTTTTACCGACGCCACACCGCTGTGGAACCCGAAC
ATCATCTTGTGCATGAGCCTGTCAAAGCTGGGCCTACCAGGTTCACGATGCGGGATTGTCATTGCCGATGAAAAAGTGAT
TTCGGCCATCACCAATATGAACGGTATTATCAGCCTGTCACCGGGCGGTATGGGGCCCGCGATCGCCGCCGAAATGATTG
AGCGTGGTGATTTATTGCGCTTATCCAACGAGGTGATCCGGCCGTTTTACTTTGAACGTGTACAGCAGACCATCGCCATC
TTGCGCAAATACCTGCCCGCTGAACGCTGCCTGATCCACAAACCCGAAGGCGCTATTTTCCTCTGGCTGTGGTTTAAAGA
TTTGCCAATCAGCACCGAACTGCTCTATCAGCGCCTGAAAAAACGTGGCGTTCTGATGGTACCGGGCCATTACTTCTTCC
CCGGTCTGGGCTATGACTGGCCACATACTCACCAATGTATGCGAATGAATTATGTGCCGGCTCCGGAAATGATTGAAAAA
GGTGTCGCGATCTTGGCGGAAGAGATTGAACGGGCGTTTCAGGAAGCGAAACAACTTACTGATTAA

Upstream 100 bases:

>100_bases
GATATTTTCACGCAGTCAGAAGAAATTCTTCCGCATTGCGTCCGCTTTTATCTGCGAGTATGGTACTTGTTCACTTACAG
ATAACAATACATTTTCATTT

Downstream 100 bases:

>100_bases
TAAACATACTGTTAACTCGCCAACAGAGTGAATCGCCGTTACCCCCTTCACCAATACAAACAGGGCAGCCAATTACGCTG
CCCTGAAGTTTAATAGCCCG

Product: valine--pyruvate transaminase

Products: NA

Alternate protein names: Alanine--valine transaminase; Transaminase C [H]

Number of amino acids: Translated: 421; Mature: 421

Protein sequence:

>421_residues
MKFSLFGDKFTRYAGITRLMDDLNDGLRTPGSIMLGGGNPAHIPEMDTYFQQLCQEMLTEGKLTEALCNYDGPQGKDLLL
NALAKMLRDELGWQIEPQNIALTNGSQSAFFYLFNLFAGRYADGSRHRVLFPLAPEYLGYADAGLDEDLFVSAKPNIELL
PEGQFKYHVDFEHLNITDDIGLICVSRPTNPTGNVITDEELIRLDAIAQQRNIPLLIDNAYGVPFPGIIFTDATPLWNPN
IILCMSLSKLGLPGSRCGIVIADEKVISAITNMNGIISLSPGGMGPAIAAEMIERGDLLRLSNEVIRPFYFERVQQTIAI
LRKYLPAERCLIHKPEGAIFLWLWFKDLPISTELLYQRLKKRGVLMVPGHYFFPGLGYDWPHTHQCMRMNYVPAPEMIEK
GVAILAEEIERAFQEAKQLTD

Sequences:

>Translated_421_residues
MKFSLFGDKFTRYAGITRLMDDLNDGLRTPGSIMLGGGNPAHIPEMDTYFQQLCQEMLTEGKLTEALCNYDGPQGKDLLL
NALAKMLRDELGWQIEPQNIALTNGSQSAFFYLFNLFAGRYADGSRHRVLFPLAPEYLGYADAGLDEDLFVSAKPNIELL
PEGQFKYHVDFEHLNITDDIGLICVSRPTNPTGNVITDEELIRLDAIAQQRNIPLLIDNAYGVPFPGIIFTDATPLWNPN
IILCMSLSKLGLPGSRCGIVIADEKVISAITNMNGIISLSPGGMGPAIAAEMIERGDLLRLSNEVIRPFYFERVQQTIAI
LRKYLPAERCLIHKPEGAIFLWLWFKDLPISTELLYQRLKKRGVLMVPGHYFFPGLGYDWPHTHQCMRMNYVPAPEMIEK
GVAILAEEIERAFQEAKQLTD
>Mature_421_residues
MKFSLFGDKFTRYAGITRLMDDLNDGLRTPGSIMLGGGNPAHIPEMDTYFQQLCQEMLTEGKLTEALCNYDGPQGKDLLL
NALAKMLRDELGWQIEPQNIALTNGSQSAFFYLFNLFAGRYADGSRHRVLFPLAPEYLGYADAGLDEDLFVSAKPNIELL
PEGQFKYHVDFEHLNITDDIGLICVSRPTNPTGNVITDEELIRLDAIAQQRNIPLLIDNAYGVPFPGIIFTDATPLWNPN
IILCMSLSKLGLPGSRCGIVIADEKVISAITNMNGIISLSPGGMGPAIAAEMIERGDLLRLSNEVIRPFYFERVQQTIAI
LRKYLPAERCLIHKPEGAIFLWLWFKDLPISTELLYQRLKKRGVLMVPGHYFFPGLGYDWPHTHQCMRMNYVPAPEMIEK
GVAILAEEIERAFQEAKQLTD

Specific function: Unknown

COG id: COG3977

COG function: function code E; Alanine-alpha-ketoisovalerate (or valine-pyruvate) aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI48994949, Length=416, Percent_Identity=79.3269230769231, Blast_Score=699, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.66 [H]

Molecular weight: Translated: 47261; Mature: 47261

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFSLFGDKFTRYAGITRLMDDLNDGLRTPGSIMLGGGNPAHIPEMDTYFQQLCQEMLTE
CCEECCCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHC
GKLTEALCNYDGPQGKDLLLNALAKMLRDELGWQIEPQNIALTNGSQSAFFYLFNLFAGR
CHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCEECCCEEEEECCCCHHHHHHHHHHHCC
YADGSRHRVLFPLAPEYLGYADAGLDEDLFVSAKPNIELLPEGQFKYHVDFEHLNITDDI
CCCCCCCEEEEECCHHHCCCCCCCCCCCEEEECCCCEEEEECCCEEEEEEEEEECCCCCC
GLICVSRPTNPTGNVITDEELIRLDAIAQQRNIPLLIDNAYGVPFPGIIFTDATPLWNPN
CEEEEECCCCCCCCEECHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEECCCCCCCCC
IILCMSLSKLGLPGSRCGIVIADEKVISAITNMNGIISLSPGGMGPAIAAEMIERGDLLR
EEEEEEHHHCCCCCCCCEEEEECHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHCCCHHH
LSNEVIRPFYFERVQQTIAILRKYLPAERCLIHKPEGAIFLWLWFKDLPISTELLYQRLK
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHEEECCCCCEEEEEEEECCCCCHHHHHHHHH
KRGVLMVPGHYFFPGLGYDWPHTHQCMRMNYVPAPEMIEKGVAILAEEIERAFQEAKQLT
HCCEEEECCCCCCCCCCCCCCCCCHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
D
C
>Mature Secondary Structure
MKFSLFGDKFTRYAGITRLMDDLNDGLRTPGSIMLGGGNPAHIPEMDTYFQQLCQEMLTE
CCEECCCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHC
GKLTEALCNYDGPQGKDLLLNALAKMLRDELGWQIEPQNIALTNGSQSAFFYLFNLFAGR
CHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCEECCCEEEEECCCCHHHHHHHHHHHCC
YADGSRHRVLFPLAPEYLGYADAGLDEDLFVSAKPNIELLPEGQFKYHVDFEHLNITDDI
CCCCCCCEEEEECCHHHCCCCCCCCCCCEEEECCCCEEEEECCCEEEEEEEEEECCCCCC
GLICVSRPTNPTGNVITDEELIRLDAIAQQRNIPLLIDNAYGVPFPGIIFTDATPLWNPN
CEEEEECCCCCCCCEECHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEECCCCCCCCC
IILCMSLSKLGLPGSRCGIVIADEKVISAITNMNGIISLSPGGMGPAIAAEMIERGDLLR
EEEEEEHHHCCCCCCCCEEEEECHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHCCCHHH
LSNEVIRPFYFERVQQTIAILRKYLPAERCLIHKPEGAIFLWLWFKDLPISTELLYQRLK
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHEEECCCCCEEEEEEEECCCCCHHHHHHHHH
KRGVLMVPGHYFFPGLGYDWPHTHQCMRMNYVPAPEMIEKGVAILAEEIERAFQEAKQLT
HCCEEEECCCCCCCCCCCCCCCCCHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
D
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2825136; 8041620; 9278503 [H]