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The map label for this gene is uvrC [H]

Identifier: 153949922

GI number: 153949922

Start: 2558158

End: 2559990

Strand: Reverse

Name: uvrC [H]

Synonym: YpsIP31758_2252

Alternate gene names: 153949922

Gene position: 2559990-2558158 (Counterclockwise)

Preceding gene: 153947332

Following gene: 153949455

Centisome position: 54.2

GC content: 44.74

Gene sequence:

>1833_bases
GTGACTGATCTTTTTGATTATAAAGAATTTTTGAAAACTGTTACTAGTCAGCCTGGTGTTTATCGGATGTACGATACTGC
AGGAACAGTTATTTATGTCGGTAAAGCAAAAGATCTCAAAAAGCGTCTGACGAGCTATTTTCGTGCTCAGGTCGCCAACC
GAAAAACTGAAACGTTAGTTAAAAATATTGCTCAAATTGATGTCACCGTTACGCATACTGAAACGGAAGCATTGTTGCTT
GAGCACAATTACATCAAGCTTTATCAGCCACGTTACAATGTGTTGCTACGTGATGATAAGTCATATCCGCTTATTTTCTT
GAGTGCGGATGAGCACCCGCGCCTTGCTGTACACCGTGGCGCAAAACATGAGAAAGGGGAGTATTTTGGGCCGTTTCCAA
ACTCCTATGCAGTGCGTGAAACGTTGGCATTATTACAGAAGCTTTTTCCAGTAAGGCAATGTGAGAATAGTGTTTACCGC
AATCGCTCACGGCCTTGCCTACAATATCAGATTGGGCGTTGTTCCGGGCCTTGTGTGGAGGGGTTGGTAAGTGAAGAGGA
GTATCAGCGCCAAGTTGATTACGTTCGCTTGTTCCTCTCAGGTAAAGATCAGCAAGTCTTGACGCAGCTAATCACCCGTA
TGGAGGAGGCTAGCCAGCAACTGCATTTTGAAGATGCAGCACGGATTCGCGATCAAATCCAAGCTGTGCGTCGAGTAACG
GAACAACAGTTTGTTTCTGGCGACAGTGAAGATCTTGATGTTATCGGTGTGGCATTTGATGCGGGGCTCGCTTGTGTCCA
TGTACTGTTTATCAGATTAGGGAAAGTATTAGGTAGCCGGAGTTATTTCCCTAAAGTTCCCGCGGGTACTGAGTTGAGCG
AAGTCGTTCAGACTTTTGTTGGGCAGTTTTATTTGCAAGGAAGCCAAGGGCGTACATTGCCTGGTGAAATTTTACTGGAT
TTTACCCTCACAGAAAAAGACCTGTTGGCATCTTCTCTTTCTGAACTGGCTGGGCGAAAAATTCAGATACAAAGCCGCCC
CCGAGGAGATCGTGCGCGTTATCTCAAGTTAGCACGTACCAATGCTTCAACCGCATTGATAACCCGCTTATCTCAGCAAT
CGACTATTCATCAACGCATGAAGGAATTAGCCAAGGTCCTTAAGCTTGATGAAATTAATCGTATGGAATGTTTTGATATC
AGCCATACGATGGGGGAACAGACCGTAGCCTCTTGTGTCGTATTTGATGCGAATGGTCCTGTACGATCTGAATATCGGCG
CTACAATATTAGTGGTATCACGCCGGGTGATGATTATGCAGCGATGGCTCAAGTACTAAAACGTCGATATGGGAAAGCAT
TAGACGATCAAAAAATTCCTGATGTCATATTTATTGACGGTGGGAAGGGGCAGTTGTCACAGGCCTTTGATGTTTTTGCC
TCGTTGAATGTTCCGTGGGATAAGCAAAAGCCATTGCTAGTCGGTGTAGCGAAAGGTAGTGATCGCAAAGCGGGTTTAGA
AACATTATTCTTGGCATCAGAAGGTGAGGGCTTTTCTTTACCCCCAGATTCACCAGCATTACATCTGATCCAGCATATTC
GTGATGATTCTCATAATCATGCGATAACCGGGCACCGGCAGCGGCGATCTAAAGTAAAAAATACCAGTGCGTTAGAAATG
ATAGAAGGTGTTGGCCCCAAACGACGGCAAGTTTTGTTGAAATATATGGGTGGACTACAACCTTTGTTTAACGCAAGCGT
CGAGGAAATTGCAAAAGTGCCGGGTATTTCACAAGCATTGGCAGAAAAAATCCACAATGCATTGAAACACTGA

Upstream 100 bases:

>100_bases
CGCTACCGTATGTTCAGTAAACTCAATATTAGTGGTGACGTTGAATTAACCCATTTGGCTATTCGCCACGGTTTATTTAA
TGCGGAGACGTTATCAAATA

Downstream 100 bases:

>100_bases
AGCTAATGTTGCACCATACTCATAGTGTCCACACCAGCCAGATAGTTATCGTAGCATTATGCAATTGAATATACCGACTT
GGCTTACCTTGTTCCGTGTT

Product: excinuclease ABC subunit C

Products: NA

Alternate protein names: Protein uvrC; Excinuclease ABC subunit C [H]

Number of amino acids: Translated: 610; Mature: 609

Protein sequence:

>610_residues
MTDLFDYKEFLKTVTSQPGVYRMYDTAGTVIYVGKAKDLKKRLTSYFRAQVANRKTETLVKNIAQIDVTVTHTETEALLL
EHNYIKLYQPRYNVLLRDDKSYPLIFLSADEHPRLAVHRGAKHEKGEYFGPFPNSYAVRETLALLQKLFPVRQCENSVYR
NRSRPCLQYQIGRCSGPCVEGLVSEEEYQRQVDYVRLFLSGKDQQVLTQLITRMEEASQQLHFEDAARIRDQIQAVRRVT
EQQFVSGDSEDLDVIGVAFDAGLACVHVLFIRLGKVLGSRSYFPKVPAGTELSEVVQTFVGQFYLQGSQGRTLPGEILLD
FTLTEKDLLASSLSELAGRKIQIQSRPRGDRARYLKLARTNASTALITRLSQQSTIHQRMKELAKVLKLDEINRMECFDI
SHTMGEQTVASCVVFDANGPVRSEYRRYNISGITPGDDYAAMAQVLKRRYGKALDDQKIPDVIFIDGGKGQLSQAFDVFA
SLNVPWDKQKPLLVGVAKGSDRKAGLETLFLASEGEGFSLPPDSPALHLIQHIRDDSHNHAITGHRQRRSKVKNTSALEM
IEGVGPKRRQVLLKYMGGLQPLFNASVEEIAKVPGISQALAEKIHNALKH

Sequences:

>Translated_610_residues
MTDLFDYKEFLKTVTSQPGVYRMYDTAGTVIYVGKAKDLKKRLTSYFRAQVANRKTETLVKNIAQIDVTVTHTETEALLL
EHNYIKLYQPRYNVLLRDDKSYPLIFLSADEHPRLAVHRGAKHEKGEYFGPFPNSYAVRETLALLQKLFPVRQCENSVYR
NRSRPCLQYQIGRCSGPCVEGLVSEEEYQRQVDYVRLFLSGKDQQVLTQLITRMEEASQQLHFEDAARIRDQIQAVRRVT
EQQFVSGDSEDLDVIGVAFDAGLACVHVLFIRLGKVLGSRSYFPKVPAGTELSEVVQTFVGQFYLQGSQGRTLPGEILLD
FTLTEKDLLASSLSELAGRKIQIQSRPRGDRARYLKLARTNASTALITRLSQQSTIHQRMKELAKVLKLDEINRMECFDI
SHTMGEQTVASCVVFDANGPVRSEYRRYNISGITPGDDYAAMAQVLKRRYGKALDDQKIPDVIFIDGGKGQLSQAFDVFA
SLNVPWDKQKPLLVGVAKGSDRKAGLETLFLASEGEGFSLPPDSPALHLIQHIRDDSHNHAITGHRQRRSKVKNTSALEM
IEGVGPKRRQVLLKYMGGLQPLFNASVEEIAKVPGISQALAEKIHNALKH
>Mature_609_residues
TDLFDYKEFLKTVTSQPGVYRMYDTAGTVIYVGKAKDLKKRLTSYFRAQVANRKTETLVKNIAQIDVTVTHTETEALLLE
HNYIKLYQPRYNVLLRDDKSYPLIFLSADEHPRLAVHRGAKHEKGEYFGPFPNSYAVRETLALLQKLFPVRQCENSVYRN
RSRPCLQYQIGRCSGPCVEGLVSEEEYQRQVDYVRLFLSGKDQQVLTQLITRMEEASQQLHFEDAARIRDQIQAVRRVTE
QQFVSGDSEDLDVIGVAFDAGLACVHVLFIRLGKVLGSRSYFPKVPAGTELSEVVQTFVGQFYLQGSQGRTLPGEILLDF
TLTEKDLLASSLSELAGRKIQIQSRPRGDRARYLKLARTNASTALITRLSQQSTIHQRMKELAKVLKLDEINRMECFDIS
HTMGEQTVASCVVFDANGPVRSEYRRYNISGITPGDDYAAMAQVLKRRYGKALDDQKIPDVIFIDGGKGQLSQAFDVFAS
LNVPWDKQKPLLVGVAKGSDRKAGLETLFLASEGEGFSLPPDSPALHLIQHIRDDSHNHAITGHRQRRSKVKNTSALEMI
EGVGPKRRQVLLKYMGGLQPLFNASVEEIAKVPGISQALAEKIHNALKH

Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision [H]

COG id: COG0322

COG function: function code L; Nuclease subunit of the excinuclease complex

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Escherichia coli, GI87081999, Length=610, Percent_Identity=83.4426229508197, Blast_Score=1071, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003583
- InterPro:   IPR010994
- InterPro:   IPR001943
- InterPro:   IPR009055
- InterPro:   IPR004791
- InterPro:   IPR001162
- InterPro:   IPR000305 [H]

Pfam domain/function: PF01541 GIY-YIG; PF02151 UVR; PF08459 UvrC_HhH_N [H]

EC number: NA

Molecular weight: Translated: 68694; Mature: 68562

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: PS50151 UVR ; PS50164 UVRC_1 ; PS50165 UVRC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDLFDYKEFLKTVTSQPGVYRMYDTAGTVIYVGKAKDLKKRLTSYFRAQVANRKTETLV
CCCHHHHHHHHHHHHCCCCEEEEEECCCCEEEEECHHHHHHHHHHHHHHHHHCCHHHHHH
KNIAQIDVTVTHTETEALLLEHNYIKLYQPRYNVLLRDDKSYPLIFLSADEHPRLAVHRG
HHHHHEEEEEEECCCEEEEEECCEEEEECCCCCEEEECCCCCCEEEEECCCCCCCHHHCC
AKHEKGEYFGPFPNSYAVRETLALLQKLFPVRQCENSVYRNRSRPCLQYQIGRCSGPCVE
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHEECCCCCCHHHH
GLVSEEEYQRQVDYVRLFLSGKDQQVLTQLITRMEEASQQLHFEDAARIRDQIQAVRRVT
HHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQQFVSGDSEDLDVIGVAFDAGLACVHVLFIRLGKVLGSRSYFPKVPAGTELSEVVQTFV
HHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
GQFYLQGSQGRTLPGEILLDFTLTEKDLLASSLSELAGRKIQIQSRPRGDRARYLKLART
HHHEEECCCCCCCCCCEEEEEECCHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHC
NASTALITRLSQQSTIHQRMKELAKVLKLDEINRMECFDISHTMGEQTVASCVVFDANGP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECHHHHCHHHHHEEEEECCCCC
VRSEYRRYNISGITPGDDYAAMAQVLKRRYGKALDDQKIPDVIFIDGGKGQLSQAFDVFA
HHHHHHEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCHHHHHHHHHH
SLNVPWDKQKPLLVGVAKGSDRKAGLETLFLASEGEGFSLPPDSPALHLIQHIRDDSHNH
HCCCCCCCCCCEEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCC
AITGHRQRRSKVKNTSALEMIEGVGPKRRQVLLKYMGGLQPLFNASVEEIAKVPGISQAL
CCCCCHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHCCHHHHHHCCCHHHHH
AEKIHNALKH
HHHHHHHHCC
>Mature Secondary Structure 
TDLFDYKEFLKTVTSQPGVYRMYDTAGTVIYVGKAKDLKKRLTSYFRAQVANRKTETLV
CCHHHHHHHHHHHHCCCCEEEEEECCCCEEEEECHHHHHHHHHHHHHHHHHCCHHHHHH
KNIAQIDVTVTHTETEALLLEHNYIKLYQPRYNVLLRDDKSYPLIFLSADEHPRLAVHRG
HHHHHEEEEEEECCCEEEEEECCEEEEECCCCCEEEECCCCCCEEEEECCCCCCCHHHCC
AKHEKGEYFGPFPNSYAVRETLALLQKLFPVRQCENSVYRNRSRPCLQYQIGRCSGPCVE
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHEECCCCCCHHHH
GLVSEEEYQRQVDYVRLFLSGKDQQVLTQLITRMEEASQQLHFEDAARIRDQIQAVRRVT
HHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQQFVSGDSEDLDVIGVAFDAGLACVHVLFIRLGKVLGSRSYFPKVPAGTELSEVVQTFV
HHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
GQFYLQGSQGRTLPGEILLDFTLTEKDLLASSLSELAGRKIQIQSRPRGDRARYLKLART
HHHEEECCCCCCCCCCEEEEEECCHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHC
NASTALITRLSQQSTIHQRMKELAKVLKLDEINRMECFDISHTMGEQTVASCVVFDANGP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECHHHHCHHHHHEEEEECCCCC
VRSEYRRYNISGITPGDDYAAMAQVLKRRYGKALDDQKIPDVIFIDGGKGQLSQAFDVFA
HHHHHHEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCHHHHHHHHHH
SLNVPWDKQKPLLVGVAKGSDRKAGLETLFLASEGEGFSLPPDSPALHLIQHIRDDSHNH
HCCCCCCCCCCEEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCC
AITGHRQRRSKVKNTSALEMIEGVGPKRRQVLLKYMGGLQPLFNASVEEIAKVPGISQAL
CCCCCHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHCCHHHHHHCCCHHHHH
AEKIHNALKH
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA