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The map label for this gene is hcr [H]

Identifier: 153949870

GI number: 153949870

Start: 2973593

End: 2974615

Strand: Direct

Name: hcr [H]

Synonym: YpsIP31758_2618

Alternate gene names: 153949870

Gene position: 2973593-2974615 (Clockwise)

Preceding gene: 153947247

Following gene: 153948591

Centisome position: 62.96

GC content: 53.18

Gene sequence:

>1023_bases
ATGACCGATTTTATTCCAACCGATTCCCCTACCCCCTTCTGCCCTAACCGTATGCAGGTCCATTCCATCGTGCAAGAGAC
GCCCGATGTCTGGAGCCTACGGCTGATTAATCACGATTTTTACTCTTATTTGCCGGGCCAATACGCGTTGGTGAGTATTC
GCAACAGTGATGAAACCTTGCGCGCCTATACCCTCTCCTCGACACCGGGTTTAAGCCCTTTTATCCAACTCACCGTGCGC
TGTTTACCTGATGGTGAAGGCTCCCGCTGGCTGACGCAGCAGGTTAATGTCGGGGATTATCTGTGGCTTTCTGATGCTCA
GGGCGAGTTTACCTGCGCCAATGCCGATGATGACCACTATCTGATGCTGGCGGCGGGCTGTGGCGTCACACCCGTAATAT
CAATGTGTCGCGCACTACTGGCTCAGCGCCCACAGGCCGATATTCGGGTAATTTTTAATGTCCGCACCCCTGCCGATGTC
ATTTTTGCCAATGAATGGCACACCTTATTGCAGCGCTATCCACAGCAATTAAAACTCACGCTGATGGCAGAGTCAGCGGC
AACGGCGGGGTTTATTGAGGGGCGAATTAATGCCCGTATTATGCAGCAGGTCGCCCCCGACATTGCTCATCGCCGCGTGA
TGACTTGCGGGCCTGCGCCCTATATGGCGTGGGTTGAACAGTATTGCCAACAACAGCAAGTGCCTGCCGATCATTTCCAG
CAAGAGCAATTTCGTACCGCTGATGAGGTTATCGATACCAGTAATGAATTGACGATGACTATCAGCCGCCCGCTACGCAG
TGTCAACGTCCCGGTTGGCACCTCCCTGCTCTTTGCGCTGGAACAACATAAAATACCGGTTATGGCCGCCTGCCGCGCGG
GTGTTTGTGGCTCATGTAAAACCCACATTTTGCATGGCAAATACACCACCACCAGCACCATGACGCTAACGCCGGAAGAA
ATAGCGCAAGGTTATGTTCTGGCATGCAGTTGCCAACTTCAGGGGGATGTCCAATTGGCGTGA

Upstream 100 bases:

>100_bases
TGCCTGGTCAATCGCCTTTCTCGCCGTTGACCGGGCTATTATTGCACGCTGTTTGCGACGTCTTTTGCCAGAGAATGACC
TGATTCATTGTGAGGCCCCA

Downstream 100 bases:

>100_bases
TAGCGCCATTGGCCTGACGACGACCGACCTTCCCGCCCCATAAAGTGCCTATCCGCATCATCAATGGGGCATTTATCCTC
AAACACGCCATACTTTGACC

Product: HCP oxidoreductase, NADH-dependent

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MTDFIPTDSPTPFCPNRMQVHSIVQETPDVWSLRLINHDFYSYLPGQYALVSIRNSDETLRAYTLSSTPGLSPFIQLTVR
CLPDGEGSRWLTQQVNVGDYLWLSDAQGEFTCANADDDHYLMLAAGCGVTPVISMCRALLAQRPQADIRVIFNVRTPADV
IFANEWHTLLQRYPQQLKLTLMAESAATAGFIEGRINARIMQQVAPDIAHRRVMTCGPAPYMAWVEQYCQQQQVPADHFQ
QEQFRTADEVIDTSNELTMTISRPLRSVNVPVGTSLLFALEQHKIPVMAACRAGVCGSCKTHILHGKYTTTSTMTLTPEE
IAQGYVLACSCQLQGDVQLA

Sequences:

>Translated_340_residues
MTDFIPTDSPTPFCPNRMQVHSIVQETPDVWSLRLINHDFYSYLPGQYALVSIRNSDETLRAYTLSSTPGLSPFIQLTVR
CLPDGEGSRWLTQQVNVGDYLWLSDAQGEFTCANADDDHYLMLAAGCGVTPVISMCRALLAQRPQADIRVIFNVRTPADV
IFANEWHTLLQRYPQQLKLTLMAESAATAGFIEGRINARIMQQVAPDIAHRRVMTCGPAPYMAWVEQYCQQQQVPADHFQ
QEQFRTADEVIDTSNELTMTISRPLRSVNVPVGTSLLFALEQHKIPVMAACRAGVCGSCKTHILHGKYTTTSTMTLTPEE
IAQGYVLACSCQLQGDVQLA
>Mature_339_residues
TDFIPTDSPTPFCPNRMQVHSIVQETPDVWSLRLINHDFYSYLPGQYALVSIRNSDETLRAYTLSSTPGLSPFIQLTVRC
LPDGEGSRWLTQQVNVGDYLWLSDAQGEFTCANADDDHYLMLAAGCGVTPVISMCRALLAQRPQADIRVIFNVRTPADVI
FANEWHTLLQRYPQQLKLTLMAESAATAGFIEGRINARIMQQVAPDIAHRRVMTCGPAPYMAWVEQYCQQQQVPADHFQQ
EQFRTADEVIDTSNELTMTISRPLRSVNVPVGTSLLFALEQHKIPVMAACRAGVCGSCKTHILHGKYTTTSTMTLTPEEI
AQGYVLACSCQLQGDVQLA

Specific function: NADH oxidoreductase acting in concert with HCP [H]

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Escherichia coli, GI1787098, Length=331, Percent_Identity=59.5166163141994, Blast_Score=385, Evalue=1e-108,
Organism=Escherichia coli, GI1787658, Length=307, Percent_Identity=26.7100977198697, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1788104, Length=298, Percent_Identity=29.1946308724832, Blast_Score=105, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR017927
- InterPro:   IPR001041
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR000951
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00111 Fer2; PF00175 NAD_binding_1 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 37877; Mature: 37745

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDFIPTDSPTPFCPNRMQVHSIVQETPDVWSLRLINHDFYSYLPGQYALVSIRNSDETL
CCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCHHHHHCCCCEEEEEEECCCCEE
RAYTLSSTPGLSPFIQLTVRCLPDGEGSRWLTQQVNVGDYLWLSDAQGEFTCANADDDHY
EEEEECCCCCCCHHHEEEEEECCCCCCCCEEEEECCCCCEEEEECCCCCEEEECCCCCCE
LMLAAGCGVTPVISMCRALLAQRPQADIRVIFNVRTPADVIFANEWHTLLQRYPQQLKLT
EEEEECCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEECHHHHHHHHCHHHEEEE
LMAESAATAGFIEGRINARIMQQVAPDIAHRRVMTCGPAPYMAWVEQYCQQQQVPADHFQ
EEECCCCCCHHHCCHHHHHHHHHHHHHHHHCEEEECCCCHHHHHHHHHHHHCCCCHHHHH
QEQFRTADEVIDTSNELTMTISRPLRSVNVPVGTSLLFALEQHKIPVMAACRAGVCGSCK
HHHHHHHHHHHCCCCCEEEEEECCHHHCCCCCCHHHHHHHHHCCCCHHHHHCCCCCCCCC
THILHGKYTTTSTMTLTPEEIAQGYVLACSCQLQGDVQLA
CEEEECCEECCEEEEECHHHHHCCEEEEEEEEECCCEEEC
>Mature Secondary Structure 
TDFIPTDSPTPFCPNRMQVHSIVQETPDVWSLRLINHDFYSYLPGQYALVSIRNSDETL
CCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCHHHHHCCCCEEEEEEECCCCEE
RAYTLSSTPGLSPFIQLTVRCLPDGEGSRWLTQQVNVGDYLWLSDAQGEFTCANADDDHY
EEEEECCCCCCCHHHEEEEEECCCCCCCCEEEEECCCCCEEEEECCCCCEEEECCCCCCE
LMLAAGCGVTPVISMCRALLAQRPQADIRVIFNVRTPADVIFANEWHTLLQRYPQQLKLT
EEEEECCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEECHHHHHHHHCHHHEEEE
LMAESAATAGFIEGRINARIMQQVAPDIAHRRVMTCGPAPYMAWVEQYCQQQQVPADHFQ
EEECCCCCCHHHCCHHHHHHHHHHHHHHHHCEEEECCCCHHHHHHHHHHHHCCCCHHHHH
QEQFRTADEVIDTSNELTMTISRPLRSVNVPVGTSLLFALEQHKIPVMAACRAGVCGSCK
HHHHHHHHHHHCCCCCEEEEEECCHHHCCCCCCHHHHHHHHHCCCCHHHHHCCCCCCCCC
THILHGKYTTTSTMTLTPEEIAQGYVLACSCQLQGDVQLA
CEEEECCEECCEEEEECHHHHHCCEEEEEEEEECCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 10651802 [H]