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The map label for this gene is hflX [H]

Identifier: 153949543

GI number: 153949543

Start: 4116645

End: 4117931

Strand: Reverse

Name: hflX [H]

Synonym: YpsIP31758_3652

Alternate gene names: 153949543

Gene position: 4117931-4116645 (Counterclockwise)

Preceding gene: 153947063

Following gene: 153950662

Centisome position: 87.18

GC content: 49.11

Gene sequence:

>1287_bases
TTGTTTGACCGCTATGAAGCTGGTGAGCAGGCCGTACTGGTTCATATTTATTTCTCGCAAAACAAAGACACAGAGGATCT
GCGCGAGTTTGAAGCGCTGGTATCTTCTGCGGGTGTAGAGGCTTTGCAAATTGTGACGGGTAGTCGCAAAGCACCACATC
CTAAATACTTTGTTGGTGAAGGAAAGGCCGAAGAAATTGCAGACGCGGTGAAAGCCAGCGGTGCGTCTGTCGTCTTGTTT
GATCATGCCCTTTCTGCGGCACAAGAGCGAAATCTTGAGCGTTTGTGTCAGTGTCGGGTGATTGATCGCACTGGGTTGAT
TTTAGACATTTTTGCCCAACGAGCTCGTACCCATGAAGGTAAACTACAGGTCGAGTTAGCGCAATTGCGTCATATCGCGA
CCCGTTTGGTTCGTGGTTGGACGCATCTTGAGCGTCAGAAGGGCGGGATTGGTCTGAGAGGGCCTGGGGAAACCCAGTTG
GAAACTGACCGCCGTTTGCTACGTGATCGTATCAGCTTGATTTTAAGCCGTTTGGAGCGTGTAGCGAAGCAGCGTGAGCA
GGGGCGGCGTGCGCGTACCCGTGCTGATATTCCGACGGTGTCCTTGGTAGGATATACCAACGCAGGTAAATCCAGCCTGT
TTAACAAAATTACGGCAGCTGATGTTTACGCAGCTGACCAATTATTTGCCACACTGGACCCTACTTTACGCCGTATAAAT
GTGGCTGATGTAGGTGATACAGTACTGGCGGATACGGTAGGTTTTATCCGGCATTTGCCGCATGATCTGGTTGCTGCGTT
CAAAGCGACACTACAAGAAACGCGGCAAGCCTCATTACTGCTACACATTATTGATGCAGTTGATCCTCGGGTCGCCGAGA
ATATGGCTGCGGTAGATACGGTATTGGCAGAAATTGAAGCAGATGAAATCCCTACATTATTAGTAATGAATAAAATTGAT
TTGTTGGACGATTTTGTTCCGCGAATCGATCGCAACGAAGACAATCTGCCAGTCAGAGTTTGGCTTTCAGCCCAAACCGG
CGCAGGAATCCCGTTGCTCTTTCAAGCGTTGACGGAACGCCTTTCGGGTGAGATCGCACACTTTGAATTGCGCTTGCCTC
CTCAGGCAGGCCGTCTGCGTAGCCGTTTTTACCAGCTTCAGGCAATTGAAAAAGAGTGGATAGACGAGGACGGGAATGTC
GGTATGGTGGTTAGAATGCCTATCGTTGATTGGCGTCGTCTCTGTAAACAAGAGCAGGAGTTGGTCAGTTATATTCAAAA
TAATTAA

Upstream 100 bases:

>100_bases
AAAGCCCATTGCTGGTCGACCATGATGGAGAACATAAGCAACGGATTCAAGCTTATGTTCTCCGCACTAGCGGCTTTGAT
CCGTTTGAGAGGTTGCACGT

Downstream 100 bases:

>100_bases
TCTGGTGCGGTTAATTACTTGATTATGCCCAAAATAATTCGAGTAGCAAGAAGGCGGCAACTGAGCGAATCCCCAGAAAC
TGACATCAGTTAGTGACTGG

Product: GTPase HflX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MFDRYEAGEQAVLVHIYFSQNKDTEDLREFEALVSSAGVEALQIVTGSRKAPHPKYFVGEGKAEEIADAVKASGASVVLF
DHALSAAQERNLERLCQCRVIDRTGLILDIFAQRARTHEGKLQVELAQLRHIATRLVRGWTHLERQKGGIGLRGPGETQL
ETDRRLLRDRISLILSRLERVAKQREQGRRARTRADIPTVSLVGYTNAGKSSLFNKITAADVYAADQLFATLDPTLRRIN
VADVGDTVLADTVGFIRHLPHDLVAAFKATLQETRQASLLLHIIDAVDPRVAENMAAVDTVLAEIEADEIPTLLVMNKID
LLDDFVPRIDRNEDNLPVRVWLSAQTGAGIPLLFQALTERLSGEIAHFELRLPPQAGRLRSRFYQLQAIEKEWIDEDGNV
GMVVRMPIVDWRRLCKQEQELVSYIQNN

Sequences:

>Translated_428_residues
MFDRYEAGEQAVLVHIYFSQNKDTEDLREFEALVSSAGVEALQIVTGSRKAPHPKYFVGEGKAEEIADAVKASGASVVLF
DHALSAAQERNLERLCQCRVIDRTGLILDIFAQRARTHEGKLQVELAQLRHIATRLVRGWTHLERQKGGIGLRGPGETQL
ETDRRLLRDRISLILSRLERVAKQREQGRRARTRADIPTVSLVGYTNAGKSSLFNKITAADVYAADQLFATLDPTLRRIN
VADVGDTVLADTVGFIRHLPHDLVAAFKATLQETRQASLLLHIIDAVDPRVAENMAAVDTVLAEIEADEIPTLLVMNKID
LLDDFVPRIDRNEDNLPVRVWLSAQTGAGIPLLFQALTERLSGEIAHFELRLPPQAGRLRSRFYQLQAIEKEWIDEDGNV
GMVVRMPIVDWRRLCKQEQELVSYIQNN
>Mature_428_residues
MFDRYEAGEQAVLVHIYFSQNKDTEDLREFEALVSSAGVEALQIVTGSRKAPHPKYFVGEGKAEEIADAVKASGASVVLF
DHALSAAQERNLERLCQCRVIDRTGLILDIFAQRARTHEGKLQVELAQLRHIATRLVRGWTHLERQKGGIGLRGPGETQL
ETDRRLLRDRISLILSRLERVAKQREQGRRARTRADIPTVSLVGYTNAGKSSLFNKITAADVYAADQLFATLDPTLRRIN
VADVGDTVLADTVGFIRHLPHDLVAAFKATLQETRQASLLLHIIDAVDPRVAENMAAVDTVLAEIEADEIPTLLVMNKID
LLDDFVPRIDRNEDNLPVRVWLSAQTGAGIPLLFQALTERLSGEIAHFELRLPPQAGRLRSRFYQLQAIEKEWIDEDGNV
GMVVRMPIVDWRRLCKQEQELVSYIQNN

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=278, Percent_Identity=33.0935251798561, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI310133116, Length=275, Percent_Identity=33.4545454545455, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI310124269, Length=257, Percent_Identity=33.852140077821, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI310124267, Length=257, Percent_Identity=33.852140077821, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI310124171, Length=257, Percent_Identity=33.852140077821, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI310124169, Length=257, Percent_Identity=33.852140077821, Blast_Score=113, Evalue=3e-25,
Organism=Escherichia coli, GI1790615, Length=425, Percent_Identity=84.7058823529412, Blast_Score=744, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17561038, Length=288, Percent_Identity=29.5138888888889, Blast_Score=112, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24650079, Length=284, Percent_Identity=31.3380281690141, Blast_Score=98, Evalue=9e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 48060; Mature: 48060

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDRYEAGEQAVLVHIYFSQNKDTEDLREFEALVSSAGVEALQIVTGSRKAPHPKYFVGE
CCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEECC
GKAEEIADAVKASGASVVLFDHALSAAQERNLERLCQCRVIDRTGLILDIFAQRARTHEG
CCHHHHHHHHHCCCCEEEEEHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCC
KLQVELAQLRHIATRLVRGWTHLERQKGGIGLRGPGETQLETDRRLLRDRISLILSRLER
CEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VAKQREQGRRARTRADIPTVSLVGYTNAGKSSLFNKITAADVYAADQLFATLDPTLRRIN
HHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHEEE
VADVGDTVLADTVGFIRHLPHDLVAAFKATLQETRQASLLLHIIDAVDPRVAENMAAVDT
HHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
VLAEIEADEIPTLLVMNKIDLLDDFVPRIDRNEDNLPVRVWLSAQTGAGIPLLFQALTER
HHHHHCHHCCCEEHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHH
LSGEIAHFELRLPPQAGRLRSRFYQLQAIEKEWIDEDGNVGMVVRMPIVDWRRLCKQEQE
HCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHH
LVSYIQNN
HHHHHHCC
>Mature Secondary Structure
MFDRYEAGEQAVLVHIYFSQNKDTEDLREFEALVSSAGVEALQIVTGSRKAPHPKYFVGE
CCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEECC
GKAEEIADAVKASGASVVLFDHALSAAQERNLERLCQCRVIDRTGLILDIFAQRARTHEG
CCHHHHHHHHHCCCCEEEEEHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCC
KLQVELAQLRHIATRLVRGWTHLERQKGGIGLRGPGETQLETDRRLLRDRISLILSRLER
CEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VAKQREQGRRARTRADIPTVSLVGYTNAGKSSLFNKITAADVYAADQLFATLDPTLRRIN
HHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHEEE
VADVGDTVLADTVGFIRHLPHDLVAAFKATLQETRQASLLLHIIDAVDPRVAENMAAVDT
HHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
VLAEIEADEIPTLLVMNKIDLLDDFVPRIDRNEDNLPVRVWLSAQTGAGIPLLFQALTER
HHHHHCHHCCCEEHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHH
LSGEIAHFELRLPPQAGRLRSRFYQLQAIEKEWIDEDGNVGMVVRMPIVDWRRLCKQEQE
HCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHH
LVSYIQNN
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]