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The map label for this gene is adhE [H]

Identifier: 153949366

GI number: 153949366

Start: 2263660

End: 2266335

Strand: Direct

Name: adhE [H]

Synonym: YpsIP31758_1963

Alternate gene names: 153949366

Gene position: 2263660-2266335 (Clockwise)

Preceding gene: 153950837

Following gene: 153948652

Centisome position: 47.93

GC content: 46.94

Gene sequence:

>2676_bases
ATGGCTGTAACGAATGTCGCTGAACTTAACGAGCTAGTCGCACGCGTCAAGAAAGCCCAGCGCGAGTATGCCAACTTTTC
GCAAGAGCAAGTTGATAAAATCTTCCGTGCTGCAGCATTAGCCGCTGCGGATGCCCGTATTCCACTAGCCAAACTGGCTG
TAACAGAGTCTGGCATGGGTATTGTTGAAGACAAAGTGATCAAAAACCACTTTGCTTCTGAATATATTTACAATGCTTAT
AAAGATGAAAAAACCTGTGGTATTTTGTGTGAAGATAAGACCTTCGGGACGATCACTATCGCAGAACCTATTGGTCTAAT
CTGCGGTATCGTACCAACCACTAACCCTACGTCTACCGCTATTTTTAAAGCACTGATTAGCTTGAAGACACGTAACGGTA
TTATCTTCTCCCCACATCCACGCGCTAAAGACGCAACCAATAAAGCTGCGGATATCGTGCTTCAAGCCGCTATCGCAGCA
GGTGCGCCAGCGGATATTATTGGTTGGATTGATGCTCCAACAGTTGAATTATCTAATCAACTGATGCATCACCCAGACAT
TAATCTTATTCTGGCAACCGGTGGGCCAGGTATGGTTAAAGCGGCCTATAGCTCTGGTAAACCAGCCATCGGCGTAGGTG
CGGGTAATACGCCAGTCGTCGTTGACGAAACTGCAGATATTAAACGTGTTGTCGCATCTATTCTGATGTCTAAAACCTTT
GATAACGGTGTTATCTGCGCGTCAGAGCAGTCCATCATCGTTGTTGACTCGGTTTACGATGCGGTTCGCGAGCGTTTTGC
TTCTCATGGTGGCTACCTGTTACAAGGTAAAGAATTGAAAGCCGTTCAGGATATTATCCTGAAAAATGGCGGTCTAAACG
CAGCCATCGTGGGCCAGCCAGCAACTAAGATCGCTGAGATGGCTGGCATTAAAGTGCCAAGTAATACCAAGATACTTATC
GGTGAAGTCAAAGTTGTCGATGAATCAGAGCCATTTGCTCATGAAAAACTGTCGCCTACACTGGCAATGTATCGTGCTAA
AAACTTTGAAGAAGCGGTTGAAAAAGCAGAGAAACTGGTGGAGATGGGCGGTATCGGTCATACCTCTTGCCTGTACACCG
ACCAAGATAACCAGACTGCACGCGTTAAATATTTCGGCGATAAAATGAAGACCGCCCGAATTCTAATCAACACCCCTGCC
TCTCAAGGTGGTATCGGTGACTTGTATAACTTCAAGCTGGCACCGTCTCTGACGCTGGGTTGTGGTTCTTGGGGTGGTAA
CTCCATCTCTGAAAACGTCGGTCCGAAACACTTGATCAACAAGAAAACTGTGGCTAAGCGAGCAGAAAACATGTTGTGGC
ATAAACTACCGAAATCTATTTACTTCCGTCGCGGCTCTCTGCCTATAGCGTTGGAAGAAGTGGCAACTGACGGTGCAAAA
CGTGCCTTCATCGTGACTGACCGCTACTTGTTCAACAACGGTTATGCAGACCAAGTCACCAGCGTACTGAAATCTCACGG
TATTGAAACTGAAGTTTTCTTCGAAGTAGAAGCTGACCCTACCCTGAGTATCGTGCGTAAAGGTGCAGAGCAGATGAACT
CCTTCAAGCCAGACGTTATTATTGCTCTGGGTGGTGGTTCACCGATGGATGCTGCAAAAATCATGTGGGTAATGTACGAA
CATCCTGAAACGCATTTCGAAGAACTGGCATTGCGTTTTATGGATATCCGTAAACGCATTTATAAGTTCCCGAAAATGGG
TGTAAAAGCGAAATTGGTCGCTATTACAACCACATCAGGTACCGGTTCAGAAGTCACCCCGTTTGCCGTGGTTACTGATG
ACGCAACAGGCCAGAAATATCCATTGGCAGACTATGCATTGACACCAGATATGGCCATTGTTGATGCCAACCTTGTTATG
AATATGCCTAAGTCTCTGTGTGCCTTCGGTGGTCTGGATGCAGTAACGCACGCACTGGAAGCCTATGTGTCTGTACTGGC
TAATGAATACTCTGACGGCCAGGCGCTGCAAGCACTGAAGCTGTTGAAAGAATTCTTGCCAGCCAGCTACAACGAAGGGG
CTAAAAACCCAGTTGCTCGCGAACGTGTACATAATGCAGCAACAATTGCCGGTATCGCCTTTGCTAACGCCTTCTTGGGT
GTCTGTCACTCTATGGCCCACAAACTGGGTTCTGAGTTCCATATCCCACACGGCTTGGCAAATGCTATGTTGATTTCTAA
CGTTATTCGCTACAACGCGAATGACAACCCAACAAAACAGACTGCCTTCAGCCAATATGACCGCCCACAAGCGCGTCGTC
GTTATGCAGAAATTGCAGATCATTTGGGGCTGAGTGCACCGGGCGACCGTACTGCACAAAAAATCCAGAAACTGCTGGCT
TGGTTAGATGAAATCAAAGCTGAACTGGGTATCCCAGCATCGATTCGCGAAGCGGGTGTTCAGGAAGCTGACTTCTTAGC
TAAAGTAGACAAATTGTCTGAAGATGCATTTGATGACCAGTGCACAGGTGCTAACCCACGCTACCCACTGATCTCAGAGC
TGAAACAGATCCTTATGGATACTTATTACGGTCGCGAATATGTTGAAGAGTTTGACCGCGAAGAAGAAGTCGCGGCAGCT
ACTGCGCCTAAAGCTGAGAAAAAGACCAAAAAGTAA

Upstream 100 bases:

>100_bases
AACTATCTCTATTCGACCATACAGCACGCTATAGCCTGTCTATACTAGTTGCTTCAACGGCTCATTTATTAAAAGAGTTT
AACATTATCAGGAGAGCATT

Downstream 100 bases:

>100_bases
TTGTTGCCTGAAGGTCTTACCCGCATTTTCGGATAGGGTAAGCAAAAAATGATATAACCCCCGATGAGCAGCCGCTGATC
GGGGGTTTTCTTTTACAGAC

Product: bifunctional acetaldehyde-CoA/alcohol dehydrogenase

Products: NA

Alternate protein names: Alcohol dehydrogenase; ADH; Acetaldehyde dehydrogenase [acetylating]; ACDH; Pyruvate-formate-lyase deactivase; PFL deactivase [H]

Number of amino acids: Translated: 891; Mature: 890

Protein sequence:

>891_residues
MAVTNVAELNELVARVKKAQREYANFSQEQVDKIFRAAALAAADARIPLAKLAVTESGMGIVEDKVIKNHFASEYIYNAY
KDEKTCGILCEDKTFGTITIAEPIGLICGIVPTTNPTSTAIFKALISLKTRNGIIFSPHPRAKDATNKAADIVLQAAIAA
GAPADIIGWIDAPTVELSNQLMHHPDINLILATGGPGMVKAAYSSGKPAIGVGAGNTPVVVDETADIKRVVASILMSKTF
DNGVICASEQSIIVVDSVYDAVRERFASHGGYLLQGKELKAVQDIILKNGGLNAAIVGQPATKIAEMAGIKVPSNTKILI
GEVKVVDESEPFAHEKLSPTLAMYRAKNFEEAVEKAEKLVEMGGIGHTSCLYTDQDNQTARVKYFGDKMKTARILINTPA
SQGGIGDLYNFKLAPSLTLGCGSWGGNSISENVGPKHLINKKTVAKRAENMLWHKLPKSIYFRRGSLPIALEEVATDGAK
RAFIVTDRYLFNNGYADQVTSVLKSHGIETEVFFEVEADPTLSIVRKGAEQMNSFKPDVIIALGGGSPMDAAKIMWVMYE
HPETHFEELALRFMDIRKRIYKFPKMGVKAKLVAITTTSGTGSEVTPFAVVTDDATGQKYPLADYALTPDMAIVDANLVM
NMPKSLCAFGGLDAVTHALEAYVSVLANEYSDGQALQALKLLKEFLPASYNEGAKNPVARERVHNAATIAGIAFANAFLG
VCHSMAHKLGSEFHIPHGLANAMLISNVIRYNANDNPTKQTAFSQYDRPQARRRYAEIADHLGLSAPGDRTAQKIQKLLA
WLDEIKAELGIPASIREAGVQEADFLAKVDKLSEDAFDDQCTGANPRYPLISELKQILMDTYYGREYVEEFDREEEVAAA
TAPKAEKKTKK

Sequences:

>Translated_891_residues
MAVTNVAELNELVARVKKAQREYANFSQEQVDKIFRAAALAAADARIPLAKLAVTESGMGIVEDKVIKNHFASEYIYNAY
KDEKTCGILCEDKTFGTITIAEPIGLICGIVPTTNPTSTAIFKALISLKTRNGIIFSPHPRAKDATNKAADIVLQAAIAA
GAPADIIGWIDAPTVELSNQLMHHPDINLILATGGPGMVKAAYSSGKPAIGVGAGNTPVVVDETADIKRVVASILMSKTF
DNGVICASEQSIIVVDSVYDAVRERFASHGGYLLQGKELKAVQDIILKNGGLNAAIVGQPATKIAEMAGIKVPSNTKILI
GEVKVVDESEPFAHEKLSPTLAMYRAKNFEEAVEKAEKLVEMGGIGHTSCLYTDQDNQTARVKYFGDKMKTARILINTPA
SQGGIGDLYNFKLAPSLTLGCGSWGGNSISENVGPKHLINKKTVAKRAENMLWHKLPKSIYFRRGSLPIALEEVATDGAK
RAFIVTDRYLFNNGYADQVTSVLKSHGIETEVFFEVEADPTLSIVRKGAEQMNSFKPDVIIALGGGSPMDAAKIMWVMYE
HPETHFEELALRFMDIRKRIYKFPKMGVKAKLVAITTTSGTGSEVTPFAVVTDDATGQKYPLADYALTPDMAIVDANLVM
NMPKSLCAFGGLDAVTHALEAYVSVLANEYSDGQALQALKLLKEFLPASYNEGAKNPVARERVHNAATIAGIAFANAFLG
VCHSMAHKLGSEFHIPHGLANAMLISNVIRYNANDNPTKQTAFSQYDRPQARRRYAEIADHLGLSAPGDRTAQKIQKLLA
WLDEIKAELGIPASIREAGVQEADFLAKVDKLSEDAFDDQCTGANPRYPLISELKQILMDTYYGREYVEEFDREEEVAAA
TAPKAEKKTKK
>Mature_890_residues
AVTNVAELNELVARVKKAQREYANFSQEQVDKIFRAAALAAADARIPLAKLAVTESGMGIVEDKVIKNHFASEYIYNAYK
DEKTCGILCEDKTFGTITIAEPIGLICGIVPTTNPTSTAIFKALISLKTRNGIIFSPHPRAKDATNKAADIVLQAAIAAG
APADIIGWIDAPTVELSNQLMHHPDINLILATGGPGMVKAAYSSGKPAIGVGAGNTPVVVDETADIKRVVASILMSKTFD
NGVICASEQSIIVVDSVYDAVRERFASHGGYLLQGKELKAVQDIILKNGGLNAAIVGQPATKIAEMAGIKVPSNTKILIG
EVKVVDESEPFAHEKLSPTLAMYRAKNFEEAVEKAEKLVEMGGIGHTSCLYTDQDNQTARVKYFGDKMKTARILINTPAS
QGGIGDLYNFKLAPSLTLGCGSWGGNSISENVGPKHLINKKTVAKRAENMLWHKLPKSIYFRRGSLPIALEEVATDGAKR
AFIVTDRYLFNNGYADQVTSVLKSHGIETEVFFEVEADPTLSIVRKGAEQMNSFKPDVIIALGGGSPMDAAKIMWVMYEH
PETHFEELALRFMDIRKRIYKFPKMGVKAKLVAITTTSGTGSEVTPFAVVTDDATGQKYPLADYALTPDMAIVDANLVMN
MPKSLCAFGGLDAVTHALEAYVSVLANEYSDGQALQALKLLKEFLPASYNEGAKNPVARERVHNAATIAGIAFANAFLGV
CHSMAHKLGSEFHIPHGLANAMLISNVIRYNANDNPTKQTAFSQYDRPQARRRYAEIADHLGLSAPGDRTAQKIQKLLAW
LDEIKAELGIPASIREAGVQEADFLAKVDKLSEDAFDDQCTGANPRYPLISELKQILMDTYYGREYVEEFDREEEVAAAT
APKAEKKTKK

Specific function: This enzyme has three activities:ADH, ACDH, and PFL- deactivase. In aerobic conditions it acts as a hydrogen peroxide scavenger. The PFL deactivase activity catalyzes the quenching of the pyruvate-formate-lyase catalyst in an iron, NAD, and CoA dependent

COG id: COG1012

COG function: function code C; NAD-dependent aldehyde dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the iron- containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=401, Percent_Identity=25.9351620947631, Blast_Score=82, Evalue=3e-15,
Organism=Escherichia coli, GI1787493, Length=869, Percent_Identity=91.8296892980437, Blast_Score=1630, Evalue=0.0,
Organism=Escherichia coli, GI1789163, Length=402, Percent_Identity=30.8457711442786, Blast_Score=198, Evalue=1e-51,
Organism=Escherichia coli, GI48994951, Length=383, Percent_Identity=34.2036553524804, Blast_Score=196, Evalue=4e-51,
Organism=Escherichia coli, GI87082107, Length=394, Percent_Identity=32.48730964467, Blast_Score=196, Evalue=4e-51,
Organism=Escherichia coli, GI1788797, Length=339, Percent_Identity=36.283185840708, Blast_Score=191, Evalue=2e-49,
Organism=Escherichia coli, GI1789386, Length=393, Percent_Identity=25.4452926208651, Blast_Score=70, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17537053, Length=399, Percent_Identity=25.31328320802, Blast_Score=105, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6321181, Length=393, Percent_Identity=30.2798982188295, Blast_Score=178, Evalue=4e-45,
Organism=Drosophila melanogaster, GI24657991, Length=396, Percent_Identity=27.2727272727273, Blast_Score=89, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211
- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR012079 [H]

Pfam domain/function: PF00171 Aldedh; PF00465 Fe-ADH [H]

EC number: =1.1.1.1; =1.2.1.10 [H]

Molecular weight: Translated: 96633; Mature: 96502

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: PS00913 ADH_IRON_1 ; PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVTNVAELNELVARVKKAQREYANFSQEQVDKIFRAAALAAADARIPLAKLAVTESGMG
CCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHEEECCCCC
IVEDKVIKNHFASEYIYNAYKDEKTCGILCEDKTFGTITIAEPIGLICGIVPTTNPTSTA
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEECCHHHHHEECCCCCCCHHHH
IFKALISLKTRNGIIFSPHPRAKDATNKAADIVLQAAIAAGAPADIIGWIDAPTVELSNQ
HHHHHHHHHHCCCEEECCCCCCCCCCHHHHHHHHHHHHHCCCCHHEEECCCCCHHHHHHH
LMHHPDINLILATGGPGMVKAAYSSGKPAIGVGAGNTPVVVDETADIKRVVASILMSKTF
HHCCCCCEEEEEECCCCEEEEHHCCCCCEEEECCCCCCEEEECCHHHHHHHHHHHHHHCC
DNGVICASEQSIIVVDSVYDAVRERFASHGGYLLQGKELKAVQDIILKNGGLNAAIVGQP
CCCEEEECCCCEEEEHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHCCCCCEEEECCC
ATKIAEMAGIKVPSNTKILIGEVKVVDESEPFAHEKLSPTLAMYRAKNFEEAVEKAEKLV
HHHHHHHHCCCCCCCCEEEEEEEEEECCCCCCHHHHCCHHHHHHHHCCHHHHHHHHHHHH
EMGGIGHTSCLYTDQDNQTARVKYFGDKMKTARILINTPASQGGIGDLYNFKLAPSLTLG
HHCCCCCCEEEEECCCCCEEEEEEECCCCCEEEEEEECCCCCCCCCCCCEEEECCCEEEE
CGSWGGNSISENVGPKHLINKKTVAKRAENMLWHKLPKSIYFRRGSLPIALEEVATDGAK
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHEECCCCCEEHHHHHCCCCC
RAFIVTDRYLFNNGYADQVTSVLKSHGIETEVFFEVEADPTLSIVRKGAEQMNSFKPDVI
EEEEEEEHHHHCCCCHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCCCEE
IALGGGSPMDAAKIMWVMYEHPETHFEELALRFMDIRKRIYKFPKMGVKAKLVAITTTSG
EEECCCCCCCHHHEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCC
TGSEVTPFAVVTDDATGQKYPLADYALTPDMAIVDANLVMNMPKSLCAFGGLDAVTHALE
CCCCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEHHHHHHCCHHHHHHCCHHHHHHHHH
AYVSVLANEYSDGQALQALKLLKEFLPASYNEGAKNPVARERVHNAATIAGIAFANAFLG
HHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VCHSMAHKLGSEFHIPHGLANAMLISNVIRYNANDNPTKQTAFSQYDRPQARRRYAEIAD
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCHHHHHHHHHHHH
HLGLSAPGDRTAQKIQKLLAWLDEIKAELGIPASIREAGVQEADFLAKVDKLSEDAFDDQ
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCC
CTGANPRYPLISELKQILMDTYYGREYVEEFDREEEVAAATAPKAEKKTKK
CCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHCCCCCHHCCCC
>Mature Secondary Structure 
AVTNVAELNELVARVKKAQREYANFSQEQVDKIFRAAALAAADARIPLAKLAVTESGMG
CCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHEEECCCCC
IVEDKVIKNHFASEYIYNAYKDEKTCGILCEDKTFGTITIAEPIGLICGIVPTTNPTSTA
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEECCHHHHHEECCCCCCCHHHH
IFKALISLKTRNGIIFSPHPRAKDATNKAADIVLQAAIAAGAPADIIGWIDAPTVELSNQ
HHHHHHHHHHCCCEEECCCCCCCCCCHHHHHHHHHHHHHCCCCHHEEECCCCCHHHHHHH
LMHHPDINLILATGGPGMVKAAYSSGKPAIGVGAGNTPVVVDETADIKRVVASILMSKTF
HHCCCCCEEEEEECCCCEEEEHHCCCCCEEEECCCCCCEEEECCHHHHHHHHHHHHHHCC
DNGVICASEQSIIVVDSVYDAVRERFASHGGYLLQGKELKAVQDIILKNGGLNAAIVGQP
CCCEEEECCCCEEEEHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHCCCCCEEEECCC
ATKIAEMAGIKVPSNTKILIGEVKVVDESEPFAHEKLSPTLAMYRAKNFEEAVEKAEKLV
HHHHHHHHCCCCCCCCEEEEEEEEEECCCCCCHHHHCCHHHHHHHHCCHHHHHHHHHHHH
EMGGIGHTSCLYTDQDNQTARVKYFGDKMKTARILINTPASQGGIGDLYNFKLAPSLTLG
HHCCCCCCEEEEECCCCCEEEEEEECCCCCEEEEEEECCCCCCCCCCCCEEEECCCEEEE
CGSWGGNSISENVGPKHLINKKTVAKRAENMLWHKLPKSIYFRRGSLPIALEEVATDGAK
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHEECCCCCEEHHHHHCCCCC
RAFIVTDRYLFNNGYADQVTSVLKSHGIETEVFFEVEADPTLSIVRKGAEQMNSFKPDVI
EEEEEEEHHHHCCCCHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCCCEE
IALGGGSPMDAAKIMWVMYEHPETHFEELALRFMDIRKRIYKFPKMGVKAKLVAITTTSG
EEECCCCCCCHHHEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCC
TGSEVTPFAVVTDDATGQKYPLADYALTPDMAIVDANLVMNMPKSLCAFGGLDAVTHALE
CCCCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEHHHHHHCCHHHHHHCCHHHHHHHHH
AYVSVLANEYSDGQALQALKLLKEFLPASYNEGAKNPVARERVHNAATIAGIAFANAFLG
HHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VCHSMAHKLGSEFHIPHGLANAMLISNVIRYNANDNPTKQTAFSQYDRPQARRRYAEIAD
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCHHHHHHHHHHHH
HLGLSAPGDRTAQKIQKLLAWLDEIKAELGIPASIREAGVQEADFLAKVDKLSEDAFDDQ
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCC
CTGANPRYPLISELKQILMDTYYGREYVEEFDREEEVAAATAPKAEKKTKK
CCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]