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The map label for this gene is hpaX [H]

Identifier: 153949197

GI number: 153949197

Start: 2658018

End: 2659385

Strand: Reverse

Name: hpaX [H]

Synonym: YpsIP31758_2358

Alternate gene names: 153949197

Gene position: 2659385-2658018 (Counterclockwise)

Preceding gene: 153948795

Following gene: 153948091

Centisome position: 56.3

GC content: 49.2

Gene sequence:

>1368_bases
ATGAGCGATTCACTGTCTACCGCACCGGGCGTTACCCCGCCGGTCAATAAAAACACACCATTAAGTGCGCAGCAGCAGTC
CGTCATTAATAAACTGTTTCGCCGTCTGATCCCGTTCTTATTCTTGTTGTTTGTTTTTGCCTTCCTTGATCGTATCAATA
TTGGTTTTGCGGGTTTGACGATGGGGAAGGATTTAGGGCTAAGTGCCACGACCTTTGGTTTAGCGACTACATTATTCTAC
GTGACATATATCTTATTCGCGATCCCCAGCAATATCATGTTGGGGATCGTGGGTGCCAGGCGTTGGATTGCGACCATTAT
GGTGCTCTGGGGTATCGCCTCTACCGCGACCTTATTTGCCGTCGGCCCCAACAGTTTGTATCTCTTACGAATGATTGTTG
GGATCACCGAAGCCGGTTTTTTACCCGGCATTCTGGTGTATTTAACTTATTGGTTTCCGGCCCACTTTCGAGCCAGAGCC
AATGCGCTGTTTATGGTGGCGATGCCAGTGACTATGGCGCTCGGCTCTCTGGTTTCCGGCTATATTTTGGCGCTTGATGG
TTTTTTGAATATGCGTGGTTGGCAGTGGCTATTTCTGCTGGAAGGCTTTCCATCGGTCTTGCTGGGGGGGGTGGTCTGGT
TCTATCTGGACGATACCCCGCAGAAAGCGCGCTGGTTAACGAAAGAAGATAAACAGTGTCTGCAAGAGATGCTGGAGAGT
GACCGTTTGCAATTGGCGAAACAGGCGGATTATGGTGCCTTACCACAATCAGGGATGTGGCGGGAAATTTTCACCCCCGT
GGTGCTGATGTATACACTGGCTTACTTCTGTTTAACCAATACCCTAAGTGCGGTGAATATTTGGACGCCGCAGATCCTGC
AAAGTTTTAATCAGAGCAGCAGCAATATCACTATCGGTCTGCTGGCCGCTATCCCACAAGTTTGTACCATTGCCGGCATG
ATCTGGTGGAGTAGACGCTCGGATCGGGTTCAGGAACGCAAAATGCACACGGTTTTGCCGTATCTGTTTGCCGCAGCGGG
GTGGGTGCTGGCATCGGCCACACAAAATAGCGTAATCCAGTTGTTAGGGATCATTATGGCCTCGACCGGGTCATTTACGG
CGATGGCGATTTTCTGGACTACACCGGATCAATCCATCAGCCTGAGAGCCAGAGCTGTTGGTATTGCAGTGATAAATGCC
ACTGGAAATATTGGTTCGGCTGTCAGCCCGGTTTTAATTGGTTGGTTGAAAGACCAGACCGGTAACTTTAATTCCGGGCT
GTATTTCGTTGCCGGTTTATTGGTTATCGGGGCTGTTATTTTCTTGATGATTCCAATGAAAAAGGCACCTCCAAAAGCCA
TTTTCTAA

Upstream 100 bases:

>100_bases
ACAGCCGAGGCACTGGCAGCCCGCTTCGGTGTGGGTAATCATCATCCACCGCTTGCACCATCGGGTGGATATTAACCCTG
TCCGTATCGAGGACATTATC

Downstream 100 bases:

>100_bases
TGGGCTAAGGGACCCATGCCGACAAGAATGTCAGCGAGCCGGTCTTTATTTTGATGACGAGGTAAATATGAAGCCAGAAA
ATTTCCGAGCGAATAACCAA

Product: 4-hydroxyphenylacetate permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 454

Protein sequence:

>455_residues
MSDSLSTAPGVTPPVNKNTPLSAQQQSVINKLFRRLIPFLFLLFVFAFLDRINIGFAGLTMGKDLGLSATTFGLATTLFY
VTYILFAIPSNIMLGIVGARRWIATIMVLWGIASTATLFAVGPNSLYLLRMIVGITEAGFLPGILVYLTYWFPAHFRARA
NALFMVAMPVTMALGSLVSGYILALDGFLNMRGWQWLFLLEGFPSVLLGGVVWFYLDDTPQKARWLTKEDKQCLQEMLES
DRLQLAKQADYGALPQSGMWREIFTPVVLMYTLAYFCLTNTLSAVNIWTPQILQSFNQSSSNITIGLLAAIPQVCTIAGM
IWWSRRSDRVQERKMHTVLPYLFAAAGWVLASATQNSVIQLLGIIMASTGSFTAMAIFWTTPDQSISLRARAVGIAVINA
TGNIGSAVSPVLIGWLKDQTGNFNSGLYFVAGLLVIGAVIFLMIPMKKAPPKAIF

Sequences:

>Translated_455_residues
MSDSLSTAPGVTPPVNKNTPLSAQQQSVINKLFRRLIPFLFLLFVFAFLDRINIGFAGLTMGKDLGLSATTFGLATTLFY
VTYILFAIPSNIMLGIVGARRWIATIMVLWGIASTATLFAVGPNSLYLLRMIVGITEAGFLPGILVYLTYWFPAHFRARA
NALFMVAMPVTMALGSLVSGYILALDGFLNMRGWQWLFLLEGFPSVLLGGVVWFYLDDTPQKARWLTKEDKQCLQEMLES
DRLQLAKQADYGALPQSGMWREIFTPVVLMYTLAYFCLTNTLSAVNIWTPQILQSFNQSSSNITIGLLAAIPQVCTIAGM
IWWSRRSDRVQERKMHTVLPYLFAAAGWVLASATQNSVIQLLGIIMASTGSFTAMAIFWTTPDQSISLRARAVGIAVINA
TGNIGSAVSPVLIGWLKDQTGNFNSGLYFVAGLLVIGAVIFLMIPMKKAPPKAIF
>Mature_454_residues
SDSLSTAPGVTPPVNKNTPLSAQQQSVINKLFRRLIPFLFLLFVFAFLDRINIGFAGLTMGKDLGLSATTFGLATTLFYV
TYILFAIPSNIMLGIVGARRWIATIMVLWGIASTATLFAVGPNSLYLLRMIVGITEAGFLPGILVYLTYWFPAHFRARAN
ALFMVAMPVTMALGSLVSGYILALDGFLNMRGWQWLFLLEGFPSVLLGGVVWFYLDDTPQKARWLTKEDKQCLQEMLESD
RLQLAKQADYGALPQSGMWREIFTPVVLMYTLAYFCLTNTLSAVNIWTPQILQSFNQSSSNITIGLLAAIPQVCTIAGMI
WWSRRSDRVQERKMHTVLPYLFAAAGWVLASATQNSVIQLLGIIMASTGSFTAMAIFWTTPDQSISLRARAVGIAVINAT
GNIGSAVSPVLIGWLKDQTGNFNSGLYFVAGLLVIGAVIFLMIPMKKAPPKAIF

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Escherichia coli, GI87082071, Length=427, Percent_Identity=31.8501170960187, Blast_Score=216, Evalue=4e-57,
Organism=Escherichia coli, GI1789515, Length=440, Percent_Identity=25.4545454545455, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI87082320, Length=441, Percent_Identity=21.5419501133787, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1789152, Length=447, Percent_Identity=21.4765100671141, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI2367379, Length=446, Percent_Identity=23.0941704035874, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6322025, Length=410, Percent_Identity=24.6341463414634, Blast_Score=94, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6321698, Length=226, Percent_Identity=25.2212389380531, Blast_Score=78, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 49993; Mature: 49862

Theoretical pI: Translated: 10.01; Mature: 10.01

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDSLSTAPGVTPPVNKNTPLSAQQQSVINKLFRRLIPFLFLLFVFAFLDRINIGFAGLT
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
MGKDLGLSATTFGLATTLFYVTYILFAIPSNIMLGIVGARRWIATIMVLWGIASTATLFA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCEEEE
VGPNSLYLLRMIVGITEAGFLPGILVYLTYWFPAHFRARANALFMVAMPVTMALGSLVSG
ECCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHH
YILALDGFLNMRGWQWLFLLEGFPSVLLGGVVWFYLDDTPQKARWLTKEDKQCLQEMLES
HHHHHHHHHCCCCCEEEEEHHCCHHHHHHHEEEEEECCCCHHHHHCCHHHHHHHHHHHHH
DRLQLAKQADYGALPQSGMWREIFTPVVLMYTLAYFCLTNTLSAVNIWTPQILQSFNQSS
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCHHHHHHHCCCC
SNITIGLLAAIPQVCTIAGMIWWSRRSDRVQERKMHTVLPYLFAAAGWVLASATQNSVIQ
CCEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
LLGIIMASTGSFTAMAIFWTTPDQSISLRARAVGIAVINATGNIGSAVSPVLIGWLKDQT
HHHHHHHCCCCEEEEEEEEECCCCCEEEEEEEEEEEEEECCCCCCCHHHHHHHHHHHCCC
GNFNSGLYFVAGLLVIGAVIFLMIPMKKAPPKAIF
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SDSLSTAPGVTPPVNKNTPLSAQQQSVINKLFRRLIPFLFLLFVFAFLDRINIGFAGLT
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
MGKDLGLSATTFGLATTLFYVTYILFAIPSNIMLGIVGARRWIATIMVLWGIASTATLFA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCEEEE
VGPNSLYLLRMIVGITEAGFLPGILVYLTYWFPAHFRARANALFMVAMPVTMALGSLVSG
ECCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHH
YILALDGFLNMRGWQWLFLLEGFPSVLLGGVVWFYLDDTPQKARWLTKEDKQCLQEMLES
HHHHHHHHHCCCCCEEEEEHHCCHHHHHHHEEEEEECCCCHHHHHCCHHHHHHHHHHHHH
DRLQLAKQADYGALPQSGMWREIFTPVVLMYTLAYFCLTNTLSAVNIWTPQILQSFNQSS
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCHHHHHHHCCCC
SNITIGLLAAIPQVCTIAGMIWWSRRSDRVQERKMHTVLPYLFAAAGWVLASATQNSVIQ
CCEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
LLGIIMASTGSFTAMAIFWTTPDQSISLRARAVGIAVINATGNIGSAVSPVLIGWLKDQT
HHHHHHHCCCCEEEEEEEEECCCCCEEEEEEEEEEEEEECCCCCCCHHHHHHHHHHHCCC
GNFNSGLYFVAGLLVIGAVIFLMIPMKKAPPKAIF
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]