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The map label for this gene is hasE [H]

Identifier: 153949022

GI number: 153949022

Start: 146610

End: 147938

Strand: Direct

Name: hasE [H]

Synonym: YpsIP31758_0133

Alternate gene names: 153949022

Gene position: 146610-147938 (Clockwise)

Preceding gene: 153947638

Following gene: 153948772

Centisome position: 3.1

GC content: 48.46

Gene sequence:

>1329_bases
ATGTTACCTGAATCCGCCTGTTATTCGGTTGCGAATGCCAATCGCCAACCACCACTCCAAATAAACAGTGGGCGCTATCT
CAATATAGGTGGGGGGCTGGTCGTTATCGGCTTCATCGGCTTTTTACTTTGGGCGGGGTTAGCGCCGTTAGATAAAGGCG
TTGCCGTGACCGGGCTGCTTGTGGTGGCAGAAAACCGCAAAGTGATCCAGCCGCTGCAAGGGGGGCGTATTCAGCAACTG
CATGTCACTGAAGGCGACGAAATAGTGTCTGGGCAATTATTGGTCACGCTGGATGACACGGCGATACGCAATCAGCGGGA
TAATTTACAGCATCAGTATCTAAGCGCCCTTGCTCAGGAAGCACGTTTAACTGCTGAGCAAAACGATCTGGATGTGATCA
CTTTCCCGCAGGCGCTGCTTGAGCACGCAACACAACCAGCGGTTGAACGTAATATTATTTTGCAGCAACAACTTTTACAT
CACCGCCGCCAGGCGCACTTGAGTGAAATCGCCCGGTTATCGACACAGCTCACTCGCCATCAGGCTCGGCTCGATGGGTT
GCAAGCTATGCGGAGCAATCATCAACGTCAATCCAATTTATTCCAGCAACAATTAGACAGTGTGCAGTTATTGGCAAAGG
ACGGTCATATTGCCAAAAATAAATTGTTAGAAATGGAAAGCCAGTTAACCTCACTCCAGGCACGAGTAGAACAAGGTACC
AGCGATATTGCGGAAGCACATAAGCTTATCGATGAAACAGAACAACATGTTTTACAACGGCGCGAACAATATCAAAGTGA
GAATAGCGAGCAATTAGCCAAGGCGCAGCAAAACACCCAAGAATTGGTCCAACGTTTAAATATTGCAGAATATGAATTGA
GTCATACCCGTATTTTTGCACCAGTCAGTGGTTCAGTTATCGCGTTGGCTCAACACACTGTGGGTGGCGTAGTGAGCTCA
GGGCAGGCATTAATGGAAATTGTCCCCAGTGGGCAGCCGTTATTTGTTGAAGCTCAGTTGCCGGTAGAGCTAATTGATAA
GGTTACGGTCGGGCTACCTGTCGATCTCAATTTTTCTGCGTTTAATCAAAGTAATACCCCCCGGCTACAAGGCTCTGTAT
GGCGCATCGGAGCCGATCGTATACAACCACCACCTACTTCACCGCCTTATTACCCTTTAACCGTTGCGATTGATATTGAC
CCGACGGAACTGGCAATCCGTCCAGGTATGGCCGTTGATGTTTTTATCCGTACCGGAGAAAGGTCATTACTCAGCTATTT
ATTTAAGCCATTCACTGATCGTCTGCACCTCGCGTTAGCCGAGGAATAA

Upstream 100 bases:

>100_bases
TACTACATCATCACCGAAGCCATGATCACCAAAACCCTTATCACAAAAAACCTCATCACAAAAACTGTGACCATAAAAAC
CAGGGATGGAGATATAACCG

Downstream 100 bases:

>100_bases
AATATCTCGGTTAAGTTATTGGAAATAAAACATTAAAAATAAAGGAATATAATGATTTCTTATCATGAATAGATTACAGC
AGAGCAGTGAAAAACTTATA

Product: HlyD family hemolysin secretion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 442; Mature: 442

Protein sequence:

>442_residues
MLPESACYSVANANRQPPLQINSGRYLNIGGGLVVIGFIGFLLWAGLAPLDKGVAVTGLLVVAENRKVIQPLQGGRIQQL
HVTEGDEIVSGQLLVTLDDTAIRNQRDNLQHQYLSALAQEARLTAEQNDLDVITFPQALLEHATQPAVERNIILQQQLLH
HRRQAHLSEIARLSTQLTRHQARLDGLQAMRSNHQRQSNLFQQQLDSVQLLAKDGHIAKNKLLEMESQLTSLQARVEQGT
SDIAEAHKLIDETEQHVLQRREQYQSENSEQLAKAQQNTQELVQRLNIAEYELSHTRIFAPVSGSVIALAQHTVGGVVSS
GQALMEIVPSGQPLFVEAQLPVELIDKVTVGLPVDLNFSAFNQSNTPRLQGSVWRIGADRIQPPPTSPPYYPLTVAIDID
PTELAIRPGMAVDVFIRTGERSLLSYLFKPFTDRLHLALAEE

Sequences:

>Translated_442_residues
MLPESACYSVANANRQPPLQINSGRYLNIGGGLVVIGFIGFLLWAGLAPLDKGVAVTGLLVVAENRKVIQPLQGGRIQQL
HVTEGDEIVSGQLLVTLDDTAIRNQRDNLQHQYLSALAQEARLTAEQNDLDVITFPQALLEHATQPAVERNIILQQQLLH
HRRQAHLSEIARLSTQLTRHQARLDGLQAMRSNHQRQSNLFQQQLDSVQLLAKDGHIAKNKLLEMESQLTSLQARVEQGT
SDIAEAHKLIDETEQHVLQRREQYQSENSEQLAKAQQNTQELVQRLNIAEYELSHTRIFAPVSGSVIALAQHTVGGVVSS
GQALMEIVPSGQPLFVEAQLPVELIDKVTVGLPVDLNFSAFNQSNTPRLQGSVWRIGADRIQPPPTSPPYYPLTVAIDID
PTELAIRPGMAVDVFIRTGERSLLSYLFKPFTDRLHLALAEE
>Mature_442_residues
MLPESACYSVANANRQPPLQINSGRYLNIGGGLVVIGFIGFLLWAGLAPLDKGVAVTGLLVVAENRKVIQPLQGGRIQQL
HVTEGDEIVSGQLLVTLDDTAIRNQRDNLQHQYLSALAQEARLTAEQNDLDVITFPQALLEHATQPAVERNIILQQQLLH
HRRQAHLSEIARLSTQLTRHQARLDGLQAMRSNHQRQSNLFQQQLDSVQLLAKDGHIAKNKLLEMESQLTSLQARVEQGT
SDIAEAHKLIDETEQHVLQRREQYQSENSEQLAKAQQNTQELVQRLNIAEYELSHTRIFAPVSGSVIALAQHTVGGVVSS
GQALMEIVPSGQPLFVEAQLPVELIDKVTVGLPVDLNFSAFNQSNTPRLQGSVWRIGADRIQPPPTSPPYYPLTVAIDID
PTELAIRPGMAVDVFIRTGERSLLSYLFKPFTDRLHLALAEE

Specific function: Involved in the secretion of proteases A, B, C and G [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR010129 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 48986; Mature: 48986

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: PS00543 HLYD_FAMILY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPESACYSVANANRQPPLQINSGRYLNIGGGLVVIGFIGFLLWAGLAPLDKGVAVTGLL
CCCCHHHHHHHCCCCCCCEEECCCCEEEECCCHHHHHHHHHHHHCCCCCCCCCCEEEEEE
VVAENRKVIQPLQGGRIQQLHVTEGDEIVSGQLLVTLDDTAIRNQRDNLQHQYLSALAQE
EEECCCHHCCCCCCCCEEEEEECCCCCEECCEEEEEECCHHHHCHHHHHHHHHHHHHHHH
ARLTAEQNDLDVITFPQALLEHATQPAVERNIILQQQLLHHRRQAHLSEIARLSTQLTRH
HHHCCCCCCCEEEECHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QARLDGLQAMRSNHQRQSNLFQQQLDSVQLLAKDGHIAKNKLLEMESQLTSLQARVEQGT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCH
SDIAEAHKLIDETEQHVLQRREQYQSENSEQLAKAQQNTQELVQRLNIAEYELSHTRIFA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHEEECCCEEEE
PVSGSVIALAQHTVGGVVSSGQALMEIVPSGQPLFVEAQLPVELIDKVTVGLPVDLNFSA
CCCCCEEEEEHHHHHHHHHCCHHHHHHCCCCCCEEEEECCCHHHHHHHHCCCCCCCCHHH
FNQSNTPRLQGSVWRIGADRIQPPPTSPPYYPLTVAIDIDPTELAIRPGMAVDVFIRTGE
CCCCCCCCCCCCEEEECCCCCCCCCCCCCCEEEEEEEECCCHHEEECCCCEEEEEEECCH
RSLLSYLFKPFTDRLHLALAEE
HHHHHHHHHHHHHHHHEEEECC
>Mature Secondary Structure
MLPESACYSVANANRQPPLQINSGRYLNIGGGLVVIGFIGFLLWAGLAPLDKGVAVTGLL
CCCCHHHHHHHCCCCCCCEEECCCCEEEECCCHHHHHHHHHHHHCCCCCCCCCCEEEEEE
VVAENRKVIQPLQGGRIQQLHVTEGDEIVSGQLLVTLDDTAIRNQRDNLQHQYLSALAQE
EEECCCHHCCCCCCCCEEEEEECCCCCEECCEEEEEECCHHHHCHHHHHHHHHHHHHHHH
ARLTAEQNDLDVITFPQALLEHATQPAVERNIILQQQLLHHRRQAHLSEIARLSTQLTRH
HHHCCCCCCCEEEECHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QARLDGLQAMRSNHQRQSNLFQQQLDSVQLLAKDGHIAKNKLLEMESQLTSLQARVEQGT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCH
SDIAEAHKLIDETEQHVLQRREQYQSENSEQLAKAQQNTQELVQRLNIAEYELSHTRIFA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHEEECCCEEEE
PVSGSVIALAQHTVGGVVSSGQALMEIVPSGQPLFVEAQLPVELIDKVTVGLPVDLNFSA
CCCCCEEEEEHHHHHHHHHCCHHHHHHCCCCCCEEEEECCCHHHHHHHHCCCCCCCCHHH
FNQSNTPRLQGSVWRIGADRIQPPPTSPPYYPLTVAIDIDPTELAIRPGMAVDVFIRTGE
CCCCCCCCCCCCEEEECCCCCCCCCCCCCCEEEEEEEECCCHHEEECCCCEEEEEEECCH
RSLLSYLFKPFTDRLHLALAEE
HHHHHHHHHHHHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2184029 [H]