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The map label for this gene is htpG [H]

Identifier: 153948834

GI number: 153948834

Start: 3440081

End: 3441949

Strand: Reverse

Name: htpG [H]

Synonym: YpsIP31758_3055

Alternate gene names: 153948834

Gene position: 3441949-3440081 (Counterclockwise)

Preceding gene: 153948905

Following gene: 153948277

Centisome position: 72.87

GC content: 46.39

Gene sequence:

>1869_bases
ATGAAAGGTCAAGAAACCCGTGGATTCCAGTCTGAAGTAAAACAGCTCCTCCATTTGATGATTCACTCGCTTTATTCCAA
TAAAGAAATTTTTCTGCGCGAGCTGATCTCCAATGCTTCTGATGCTGCAGATAAACTCCGTTTCCGTGCCCTGTCTAACC
CCGAACTCTTTGAAGGGGATGGCGAACTGAGAGTGCGTTTATCTTTTGATAAAGAGAAACGTACTTTAACCCTGAGTGAT
AACGGCATCGGTATGACCCGTGACGAAGTCATTGATAATCTTGGTACTATCGCCAAGTCAGGGACTAAAGCATTTCTTGA
ATCAATCGGTTCTGATCAGGCCAAAGACAGCCAATTAATCGGTCAATTTGGTGTGGGTTTCTACTCAGCATTTATTGTTG
CCGATAAAGTTACCGTACGCACCCGAGCTGCCGGTGCCCCTGCCGATACCGGTGTATTCTGGGAATCTGCTGGTGAAGGT
GATTACACCATCGCCGATATAACTAAAGACGAGCGTGGTACTGAAATTACGCTACATTTGCGTGAAGGCGAAGACGAGTA
TCTGGATGACTGGCGTCTACGTTCTGTTATCAGCAAATACTCAGATCATATTGCACTGCCGGTTGAAATTCAGGTTAAAA
ATGAAGAAGACGGCACTGTCACCTGGGAAAAAATCAACAAAGCTCAGGCGTTGTGGACCCGTGGTAAAGCAGAAATCTCT
GACGACGAATACAAAGCATTTTACAAACATATTGCCCATGATTTTACCGATCCACTCAGTTGGAGTCACAACCGCGTTGA
AGGGAAGCAGGAATACACCAGCTTGCTGTATATCCCCGCGCAGGCACCATGGGATATGTGGAACCGTGATCACAAACATG
GTTTAAAACTTTATGTGCAGCGTGTGTTTATCATGGATGAAGCTGAGCAGTTTATGCCGAACTATCTGCGGTTTGTCCGT
GGTTTGATAGATTCGAACGATCTGCCGCTGAACGTCTCCCGTGAGATTTTACAAGACAGTCGTATTACACAGAATCTGCG
CAGTGCATTGACTAAGCGTGTGCTGCAAATGCTGGAAAAACTGGCTAAAGATGATGCTGAGAAATATCAGCAATTCTGGC
AACAATTCGGCATGGCATTAAAAGAAGGCCCAGCGGAAGATGGTAGCAATAAAGAGACTATCGCTAAGCTATTGCGCTTT
GCTTCAACGCATACCGACAGTTCCGCACAGACCGTGTCACTGGAAGACTATGTCAGCCGTATGGCAGAAGGGCAGGAGAA
AATTTATTACATCACTGCTGACAGCTATGCTGCTGCGAAGAGTAGCCCGCATCTGGAACTGTTCCGTAAAAAAGGTATCG
AGGTCCTATTGTTATCCGATCGTATCGACGAATGGATGATGAGCTACCTGACTGAATTCGAAGGCAAAGCGTTCCAATCG
GTCAGTAAAGCAGATGACTCACTGAATAAATTGGCTGATGAAGAAAATCCAGAGCAGCAAGAAGCAGAGAAAGCACTGGA
ACCCTTCGTTGAACGCGTAAAAACGTTATTGGGTGAGCGTGTTAAAGACGTGCGCTTGACACATCGCCTAACGGATACAC
CCGCAATCGTAACGACTGATGCGGATGAAATGAGTACGCAGATGGCTAAGCTATTCGCGGCCGCGGGTCAACAGGCTCCG
GAAGTGAAGTACATCTTTGAACTGAACCCAGATCATGGCTTGGTTAAGCGTGCTGCGGAAGTTACAGATGACACTCAATT
TGCACAATGGGTTGAGTTATTACTGGATCAGGCGCTGCTCGCGGAGAGGGGAACATTGGAAGACCCTAACCAGTTTATTC
GTCGAATGAATCAGTTACTCACGGCTTAA

Upstream 100 bases:

>100_bases
TCTGCTTTACCGCTTGAAACTGCCGCTATTGGCCCCATTTGATCTTCATTGTTCGATTTTATCTGCCTGTTGGTAATTTG
GATTGAGGTAATTAATGAAT

Downstream 100 bases:

>100_bases
TCGATAAAAAAACACCCTTGTTCAACGTATTGCCAAGGGTGTTTTTTATTGTACCTCTCTGATTTAAATCTATATTTTAT
TATTTCATTTCCTCAAATAT

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 622; Mature: 622

Protein sequence:

>622_residues
MKGQETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPELFEGDGELRVRLSFDKEKRTLTLSD
NGIGMTRDEVIDNLGTIAKSGTKAFLESIGSDQAKDSQLIGQFGVGFYSAFIVADKVTVRTRAAGAPADTGVFWESAGEG
DYTIADITKDERGTEITLHLREGEDEYLDDWRLRSVISKYSDHIALPVEIQVKNEEDGTVTWEKINKAQALWTRGKAEIS
DDEYKAFYKHIAHDFTDPLSWSHNRVEGKQEYTSLLYIPAQAPWDMWNRDHKHGLKLYVQRVFIMDEAEQFMPNYLRFVR
GLIDSNDLPLNVSREILQDSRITQNLRSALTKRVLQMLEKLAKDDAEKYQQFWQQFGMALKEGPAEDGSNKETIAKLLRF
ASTHTDSSAQTVSLEDYVSRMAEGQEKIYYITADSYAAAKSSPHLELFRKKGIEVLLLSDRIDEWMMSYLTEFEGKAFQS
VSKADDSLNKLADEENPEQQEAEKALEPFVERVKTLLGERVKDVRLTHRLTDTPAIVTTDADEMSTQMAKLFAAAGQQAP
EVKYIFELNPDHGLVKRAAEVTDDTQFAQWVELLLDQALLAERGTLEDPNQFIRRMNQLLTA

Sequences:

>Translated_622_residues
MKGQETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPELFEGDGELRVRLSFDKEKRTLTLSD
NGIGMTRDEVIDNLGTIAKSGTKAFLESIGSDQAKDSQLIGQFGVGFYSAFIVADKVTVRTRAAGAPADTGVFWESAGEG
DYTIADITKDERGTEITLHLREGEDEYLDDWRLRSVISKYSDHIALPVEIQVKNEEDGTVTWEKINKAQALWTRGKAEIS
DDEYKAFYKHIAHDFTDPLSWSHNRVEGKQEYTSLLYIPAQAPWDMWNRDHKHGLKLYVQRVFIMDEAEQFMPNYLRFVR
GLIDSNDLPLNVSREILQDSRITQNLRSALTKRVLQMLEKLAKDDAEKYQQFWQQFGMALKEGPAEDGSNKETIAKLLRF
ASTHTDSSAQTVSLEDYVSRMAEGQEKIYYITADSYAAAKSSPHLELFRKKGIEVLLLSDRIDEWMMSYLTEFEGKAFQS
VSKADDSLNKLADEENPEQQEAEKALEPFVERVKTLLGERVKDVRLTHRLTDTPAIVTTDADEMSTQMAKLFAAAGQQAP
EVKYIFELNPDHGLVKRAAEVTDDTQFAQWVELLLDQALLAERGTLEDPNQFIRRMNQLLTA
>Mature_622_residues
MKGQETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPELFEGDGELRVRLSFDKEKRTLTLSD
NGIGMTRDEVIDNLGTIAKSGTKAFLESIGSDQAKDSQLIGQFGVGFYSAFIVADKVTVRTRAAGAPADTGVFWESAGEG
DYTIADITKDERGTEITLHLREGEDEYLDDWRLRSVISKYSDHIALPVEIQVKNEEDGTVTWEKINKAQALWTRGKAEIS
DDEYKAFYKHIAHDFTDPLSWSHNRVEGKQEYTSLLYIPAQAPWDMWNRDHKHGLKLYVQRVFIMDEAEQFMPNYLRFVR
GLIDSNDLPLNVSREILQDSRITQNLRSALTKRVLQMLEKLAKDDAEKYQQFWQQFGMALKEGPAEDGSNKETIAKLLRF
ASTHTDSSAQTVSLEDYVSRMAEGQEKIYYITADSYAAAKSSPHLELFRKKGIEVLLLSDRIDEWMMSYLTEFEGKAFQS
VSKADDSLNKLADEENPEQQEAEKALEPFVERVKTLLGERVKDVRLTHRLTDTPAIVTTDADEMSTQMAKLFAAAGQQAP
EVKYIFELNPDHGLVKRAAEVTDDTQFAQWVELLLDQALLAERGTLEDPNQFIRRMNQLLTA

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI20149594, Length=681, Percent_Identity=36.8575624082232, Blast_Score=426, Evalue=1e-119,
Organism=Homo sapiens, GI4507677, Length=680, Percent_Identity=37.3529411764706, Blast_Score=413, Evalue=1e-115,
Organism=Homo sapiens, GI155722983, Length=630, Percent_Identity=36.3492063492063, Blast_Score=388, Evalue=1e-108,
Organism=Homo sapiens, GI154146191, Length=412, Percent_Identity=35.6796116504854, Blast_Score=267, Evalue=2e-71,
Organism=Homo sapiens, GI153792590, Length=409, Percent_Identity=35.9413202933985, Blast_Score=265, Evalue=8e-71,
Organism=Escherichia coli, GI1786679, Length=624, Percent_Identity=86.3782051282051, Blast_Score=1130, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17559162, Length=667, Percent_Identity=36.8815592203898, Blast_Score=446, Evalue=1e-125,
Organism=Caenorhabditis elegans, GI17542208, Length=678, Percent_Identity=37.7581120943953, Blast_Score=398, Evalue=1e-111,
Organism=Caenorhabditis elegans, GI115535205, Length=636, Percent_Identity=34.4339622641509, Blast_Score=340, Evalue=1e-93,
Organism=Caenorhabditis elegans, GI115535167, Length=429, Percent_Identity=37.7622377622378, Blast_Score=280, Evalue=2e-75,
Organism=Saccharomyces cerevisiae, GI6323840, Length=679, Percent_Identity=38.4388807069219, Blast_Score=460, Evalue=1e-130,
Organism=Saccharomyces cerevisiae, GI6325016, Length=685, Percent_Identity=37.8102189781022, Blast_Score=459, Evalue=1e-130,
Organism=Drosophila melanogaster, GI21357739, Length=677, Percent_Identity=37.370753323486, Blast_Score=400, Evalue=1e-111,
Organism=Drosophila melanogaster, GI24586016, Length=634, Percent_Identity=36.2776025236593, Blast_Score=379, Evalue=1e-105,
Organism=Drosophila melanogaster, GI17647529, Length=411, Percent_Identity=35.2798053527981, Blast_Score=265, Evalue=5e-71,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 70786; Mature: 70786

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGQETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPELFEGD
CCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCEECCC
GELRVRLSFDKEKRTLTLSDNGIGMTRDEVIDNLGTIAKSGTKAFLESIGSDQAKDSQLI
CCEEEEEEECCCCCEEEECCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHCCCCCHHHHHH
GQFGVGFYSAFIVADKVTVRTRAAGAPADTGVFWESAGEGDYTIADITKDERGTEITLHL
HHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEECCCCCCCEEEEECCCCCCCCEEEEEE
REGEDEYLDDWRLRSVISKYSDHIALPVEIQVKNEEDGTVTWEKINKAQALWTRGKAEIS
ECCCHHHHHHHHHHHHHHHHHCCEEEEEEEEEECCCCCCEEHHHHHHHHHHHHCCCCCCC
DDEYKAFYKHIAHDFTDPLSWSHNRVEGKQEYTSLLYIPAQAPWDMWNRDHKHGLKLYVQ
CHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCEEEEECCCCCHHHCCCCHHHHHHHHHH
RVFIMDEAEQFMPNYLRFVRGLIDSNDLPLNVSREILQDSRITQNLRSALTKRVLQMLEK
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAKDDAEKYQQFWQQFGMALKEGPAEDGSNKETIAKLLRFASTHTDSSAQTVSLEDYVSR
HHHHHHHHHHHHHHHHCHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEHHHHHHH
MAEGQEKIYYITADSYAAAKSSPHLELFRKKGIEVLLLSDRIDEWMMSYLTEFEGKAFQS
HHCCCCEEEEEEECCHHHCCCCCHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHCCHHHHH
VSKADDSLNKLADEENPEQQEAEKALEPFVERVKTLLGERVKDVRLTHRLTDTPAIVTTD
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECC
ADEMSTQMAKLFAAAGQQAPEVKYIFELNPDHGLVKRAAEVTDDTQFAQWVELLLDQALL
HHHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
AERGTLEDPNQFIRRMNQLLTA
HCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MKGQETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPELFEGD
CCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCEECCC
GELRVRLSFDKEKRTLTLSDNGIGMTRDEVIDNLGTIAKSGTKAFLESIGSDQAKDSQLI
CCEEEEEEECCCCCEEEECCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHCCCCCHHHHHH
GQFGVGFYSAFIVADKVTVRTRAAGAPADTGVFWESAGEGDYTIADITKDERGTEITLHL
HHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEECCCCCCCEEEEECCCCCCCCEEEEEE
REGEDEYLDDWRLRSVISKYSDHIALPVEIQVKNEEDGTVTWEKINKAQALWTRGKAEIS
ECCCHHHHHHHHHHHHHHHHHCCEEEEEEEEEECCCCCCEEHHHHHHHHHHHHCCCCCCC
DDEYKAFYKHIAHDFTDPLSWSHNRVEGKQEYTSLLYIPAQAPWDMWNRDHKHGLKLYVQ
CHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCEEEEECCCCCHHHCCCCHHHHHHHHHH
RVFIMDEAEQFMPNYLRFVRGLIDSNDLPLNVSREILQDSRITQNLRSALTKRVLQMLEK
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAKDDAEKYQQFWQQFGMALKEGPAEDGSNKETIAKLLRFASTHTDSSAQTVSLEDYVSR
HHHHHHHHHHHHHHHHCHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEHHHHHHH
MAEGQEKIYYITADSYAAAKSSPHLELFRKKGIEVLLLSDRIDEWMMSYLTEFEGKAFQS
HHCCCCEEEEEEECCHHHCCCCCHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHCCHHHHH
VSKADDSLNKLADEENPEQQEAEKALEPFVERVKTLLGERVKDVRLTHRLTDTPAIVTTD
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECC
ADEMSTQMAKLFAAAGQQAPEVKYIFELNPDHGLVKRAAEVTDDTQFAQWVELLLDQALL
HHHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
AERGTLEDPNQFIRRMNQLLTA
HCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA