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The map label for this gene is acrB [H]

Identifier: 153948753

GI number: 153948753

Start: 4045205

End: 4048330

Strand: Reverse

Name: acrB [H]

Synonym: YpsIP31758_3585

Alternate gene names: 153948753

Gene position: 4048330-4045205 (Counterclockwise)

Preceding gene: 153947901

Following gene: 153949331

Centisome position: 85.71

GC content: 52.27

Gene sequence:

>3126_bases
ATGTTTGCCCGTTTCTTTATTTATCGCCCGGTTTTTGCCTGGGTCATTGCCATTGTTATTATGTTGGGCGGGGTGGTTGC
GCTGGAAACCTTGCCGATAGCCCAGTATCCCGATGTCGCACCACCATCTATTTCCATTAAAGCCACCTATACCGGTGCTT
CAGCAGAAACACTCGAAAACAGTGTGACGCAGGTCATTGAGCAAGAACTGACCGGATTGGATGGTCTGCTCTATTTTTCC
TCCTCCAGCGGTTCCGATGGTAATGCCAAGATCGTCGCCACATTTAAGCAGGGGACTAATGCTGATACCGCGCAGGTACA
GGTGCAAAATAAGGTTCAGCAGGCGCTAACCCGTTTGCCAACAGAGGTGCAGGCGCAAGGGGTCACGGTGACCAAGTCGC
AGACTAACTTCTTGTTGATCATGTCGCTGTATGATGAAAAAGACAAACACACCGGAACGGATATTGCCGACTATCTGGTC
AGCAACCTGCAAGACCCACTGGCTCGCCTCGAAGGGGTAGGGAGTGTGCAGGTGTTTGGTTCGCAATATGCGATGCGGAT
TTGGTTAAATCCGACCAAACTGGCCGCTTACAATCTGATGCCCAGCGATGTTCAATCCGCCATTACGGCACAGAACACAC
AGGTTTCTGCTGGCAAAATCGGGGCGTTACCGAGCGGTAAAGAGCAGCAATTGACCGCGACAGTCATGGCGCAATCCCGC
CTGAAAACACCGGAGCAGTTCAACAATATTATTGTTAAAAGTGACAGCACGGGCGCGGTGGTACGACTGCGCGATGTGGC
CCGTGTTGAGCTGGGCAATGAAGATTACAGCGTGACGACCCGCTTGAACGGCCATCCAGCCGCGGGGATCGCGGTGATGC
TGGCACCTGGTGCTAATGCGCTGGCGACCGCCGAGCGGGTAAAGGCCAAGGCTGCCGAGTTTGAATTGAACTTGCCTGAC
GGATACAAAATCGCGTATCCAAAAGACAGCACTGATTTTATTAAAGTTTCGGTCGAGGAAGTGGTGAAAACGCTGATCGA
AGCCATCTTGCTGGTGGTTATCGTGATGTACATCTTCCTACAAAATATCCGTGCCACTTTGATACCGGCTATTGCCGTCC
CAGTTGTGTTGTTAGGGACGTTTGGGGTGTTGGCCATATTCGGCTACTCAATCAATACACTGACACTTTTTGGTATGGTG
CTGTCGATCGGCTTGTTGGTCGACGATGCTATTGTCGTGGTGGAAAACGTTGAGCGGGTGATGCGGGAAGACAATCTCCC
GCCCCGTGAAGCGACTGAGAAATCTATGAGTGAGATCGCCAGCGCACTGATTGGGATTGCACTGGTGCTCTCGGCAGTAT
TCCTGCCCATGGCCTTCTTTGGTGGGGCGACCGGCGTTATCTACCGCCAGTTCTCCATCACCATTGTGTCAGCGATGGCG
CTATCCGTGTTGGTCGCATTAACCCTCACGCCAGCATTGTGCGCCACCTTCCTGAAACCCAACCATAAACCGCCATCAGA
GCACGGTTTCTTCGGCGGGTTCAACCGTCGCTATGACCGGATGCAGACCCGTTATGAAAGCCTGGTAGGGCATGTTATTC
ACCGCTCTTTGCGCTATTTACTGATTTACGCCGTGCTGATTGGGGTGATGTGTGTGTTGTTTATTCGCCTGCCAACGGGC
TTTTTACCGACCGAAGATCAGGGTGATGTCATGGTGCAATATACCTTGCCAGCAGGGGCAACCAGTGGGCGCACCATGGA
GGTCAGTAAGGCGGTAGAAAACTATTTCATGACACAGGAAAAGGACAATACCAAAGCAGTCTTCACTATCTCCGGTTTTG
GCTTTAGTGGTAGTGGGCAAAATGCCGGTATGGCGTTTATTGCATTGAAACACTGGCGTGATCGACCGGGCAGTGAAAAT
ACCGCCACAGCCATTGCAGATCGCGCGATGAAGGCACTGTCGAGTATTCGCGATGCCCAAATTTTCAGTATGACGCCACC
TGCGGTGGATGGGTTAGGCCAGTCGAATGGCTTTACTTTTGAGTTGCAAGCCACAGGGGATACCAGCCGCGAGCAACTGC
TGACCTTGCGCGATCAACTGATTAGCAAGGCGAATAAAGACCCTATTTTGGCCTCAGTTCGCGCCAATACCTTGCAACAA
ATGCCGCAGTTACAAGTAGATATCGATAACGATAAAGCGGCGGCATTAGGGCTGTCGATCAGTGATGTGAATGCCACATT
AAGTGCCGCCTGGGGTGGGACGTATATCAATGACTTTATTGATCGTGGGAGAGTGAAAAAAGTGTATATGCAGGGTGATG
TGGATACCCGCTCTAAACCGGAGGATCTCAACCAATGGTTCGTGCGCGGTAGCAGTGATGCCATGACATCGTTTTCTGCC
TTTGCGACGACTCGCTGGATTTACGGCCCGGAAACGCTTTCCCGCTATAACGGGCAGACGTCCTATGAAATTCAGGGGCA
GGCCGCTTCCGGCAGCAGTTCGGGCACCGCAATGGATCAAATGGAGAAACTGGCGGCTGAATTGCCTGGCACCAGTTATG
CGTGGAGCGGGCTGTCTTATCAGGAGCGTTTAGCCAGCGGGCAAGCATTATCGCTGTATGCCATTTCAATCTTGGTGGTA
TTCCTGTGCTTGGCGGCGTTGTATGAGAGTTGGTCAGTCCCGTTCTCGGTCATGATGGTTATTCCGTTGGGGATAATCGG
TGCAGTAGCGGCAGCGACGCTGCGGGGATTGGAGAATGATATTTACTTCCAGGTGGCGTTGTTGACGACCCTGGGTCTGG
CATCGAAAAACGCCATTCTGATTGTTGAATTTGCCGAAGCCGCCTATTTACGCGGCGAACCGCTGGTGGCGGCGGCGTTG
CAGGGCGCTGCAACTCGCTTACGGCCTATCCTGATGACATCGCTGGCATTTATTGCTGGGGTAATGCCTCTGGCAATGTC
TACCGGTGCCGGCGCTAACAGCCGCATTTCAATCGGCAGCGGCATTATTGGCGGCACCTTAACGGCGACAGTGTTGGCCG
TCTTTTTTGTCCCGCTCTTTTTTGTCTTGATTCGTCGAGTGTTCAGCGGCAAGTCAAAAAATATCACTGAACATAAAGGA
GTATAA

Upstream 100 bases:

>100_bases
AAAGGTCAGTGTTGGCGATGACGTCAAACCGGTAGAGGTGAGCACTACGCTGCCCGTTGTGGCCGAACCGACTACGCCAT
CAACTGGGGAGAAATAATCG

Downstream 100 bases:

>100_bases
AATGTTCAGTCGTATACTGATATTATCGTTACCCGCGCTGCTGGCCGGATGTATTTCTCTCGATCCGGACTATCAGCGCC
CAGTGGCACCGGTTCCGGCA

Product: RND efflux transporter

Products: Proton [Cytoplasm]; multidrug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 1041; Mature: 1041

Protein sequence:

>1041_residues
MFARFFIYRPVFAWVIAIVIMLGGVVALETLPIAQYPDVAPPSISIKATYTGASAETLENSVTQVIEQELTGLDGLLYFS
SSSGSDGNAKIVATFKQGTNADTAQVQVQNKVQQALTRLPTEVQAQGVTVTKSQTNFLLIMSLYDEKDKHTGTDIADYLV
SNLQDPLARLEGVGSVQVFGSQYAMRIWLNPTKLAAYNLMPSDVQSAITAQNTQVSAGKIGALPSGKEQQLTATVMAQSR
LKTPEQFNNIIVKSDSTGAVVRLRDVARVELGNEDYSVTTRLNGHPAAGIAVMLAPGANALATAERVKAKAAEFELNLPD
GYKIAYPKDSTDFIKVSVEEVVKTLIEAILLVVIVMYIFLQNIRATLIPAIAVPVVLLGTFGVLAIFGYSINTLTLFGMV
LSIGLLVDDAIVVVENVERVMREDNLPPREATEKSMSEIASALIGIALVLSAVFLPMAFFGGATGVIYRQFSITIVSAMA
LSVLVALTLTPALCATFLKPNHKPPSEHGFFGGFNRRYDRMQTRYESLVGHVIHRSLRYLLIYAVLIGVMCVLFIRLPTG
FLPTEDQGDVMVQYTLPAGATSGRTMEVSKAVENYFMTQEKDNTKAVFTISGFGFSGSGQNAGMAFIALKHWRDRPGSEN
TATAIADRAMKALSSIRDAQIFSMTPPAVDGLGQSNGFTFELQATGDTSREQLLTLRDQLISKANKDPILASVRANTLQQ
MPQLQVDIDNDKAAALGLSISDVNATLSAAWGGTYINDFIDRGRVKKVYMQGDVDTRSKPEDLNQWFVRGSSDAMTSFSA
FATTRWIYGPETLSRYNGQTSYEIQGQAASGSSSGTAMDQMEKLAAELPGTSYAWSGLSYQERLASGQALSLYAISILVV
FLCLAALYESWSVPFSVMMVIPLGIIGAVAAATLRGLENDIYFQVALLTTLGLASKNAILIVEFAEAAYLRGEPLVAAAL
QGAATRLRPILMTSLAFIAGVMPLAMSTGAGANSRISIGSGIIGGTLTATVLAVFFVPLFFVLIRRVFSGKSKNITEHKG
V

Sequences:

>Translated_1041_residues
MFARFFIYRPVFAWVIAIVIMLGGVVALETLPIAQYPDVAPPSISIKATYTGASAETLENSVTQVIEQELTGLDGLLYFS
SSSGSDGNAKIVATFKQGTNADTAQVQVQNKVQQALTRLPTEVQAQGVTVTKSQTNFLLIMSLYDEKDKHTGTDIADYLV
SNLQDPLARLEGVGSVQVFGSQYAMRIWLNPTKLAAYNLMPSDVQSAITAQNTQVSAGKIGALPSGKEQQLTATVMAQSR
LKTPEQFNNIIVKSDSTGAVVRLRDVARVELGNEDYSVTTRLNGHPAAGIAVMLAPGANALATAERVKAKAAEFELNLPD
GYKIAYPKDSTDFIKVSVEEVVKTLIEAILLVVIVMYIFLQNIRATLIPAIAVPVVLLGTFGVLAIFGYSINTLTLFGMV
LSIGLLVDDAIVVVENVERVMREDNLPPREATEKSMSEIASALIGIALVLSAVFLPMAFFGGATGVIYRQFSITIVSAMA
LSVLVALTLTPALCATFLKPNHKPPSEHGFFGGFNRRYDRMQTRYESLVGHVIHRSLRYLLIYAVLIGVMCVLFIRLPTG
FLPTEDQGDVMVQYTLPAGATSGRTMEVSKAVENYFMTQEKDNTKAVFTISGFGFSGSGQNAGMAFIALKHWRDRPGSEN
TATAIADRAMKALSSIRDAQIFSMTPPAVDGLGQSNGFTFELQATGDTSREQLLTLRDQLISKANKDPILASVRANTLQQ
MPQLQVDIDNDKAAALGLSISDVNATLSAAWGGTYINDFIDRGRVKKVYMQGDVDTRSKPEDLNQWFVRGSSDAMTSFSA
FATTRWIYGPETLSRYNGQTSYEIQGQAASGSSSGTAMDQMEKLAAELPGTSYAWSGLSYQERLASGQALSLYAISILVV
FLCLAALYESWSVPFSVMMVIPLGIIGAVAAATLRGLENDIYFQVALLTTLGLASKNAILIVEFAEAAYLRGEPLVAAAL
QGAATRLRPILMTSLAFIAGVMPLAMSTGAGANSRISIGSGIIGGTLTATVLAVFFVPLFFVLIRRVFSGKSKNITEHKG
V
>Mature_1041_residues
MFARFFIYRPVFAWVIAIVIMLGGVVALETLPIAQYPDVAPPSISIKATYTGASAETLENSVTQVIEQELTGLDGLLYFS
SSSGSDGNAKIVATFKQGTNADTAQVQVQNKVQQALTRLPTEVQAQGVTVTKSQTNFLLIMSLYDEKDKHTGTDIADYLV
SNLQDPLARLEGVGSVQVFGSQYAMRIWLNPTKLAAYNLMPSDVQSAITAQNTQVSAGKIGALPSGKEQQLTATVMAQSR
LKTPEQFNNIIVKSDSTGAVVRLRDVARVELGNEDYSVTTRLNGHPAAGIAVMLAPGANALATAERVKAKAAEFELNLPD
GYKIAYPKDSTDFIKVSVEEVVKTLIEAILLVVIVMYIFLQNIRATLIPAIAVPVVLLGTFGVLAIFGYSINTLTLFGMV
LSIGLLVDDAIVVVENVERVMREDNLPPREATEKSMSEIASALIGIALVLSAVFLPMAFFGGATGVIYRQFSITIVSAMA
LSVLVALTLTPALCATFLKPNHKPPSEHGFFGGFNRRYDRMQTRYESLVGHVIHRSLRYLLIYAVLIGVMCVLFIRLPTG
FLPTEDQGDVMVQYTLPAGATSGRTMEVSKAVENYFMTQEKDNTKAVFTISGFGFSGSGQNAGMAFIALKHWRDRPGSEN
TATAIADRAMKALSSIRDAQIFSMTPPAVDGLGQSNGFTFELQATGDTSREQLLTLRDQLISKANKDPILASVRANTLQQ
MPQLQVDIDNDKAAALGLSISDVNATLSAAWGGTYINDFIDRGRVKKVYMQGDVDTRSKPEDLNQWFVRGSSDAMTSFSA
FATTRWIYGPETLSRYNGQTSYEIQGQAASGSSSGTAMDQMEKLAAELPGTSYAWSGLSYQERLASGQALSLYAISILVV
FLCLAALYESWSVPFSVMMVIPLGIIGAVAAATLRGLENDIYFQVALLTTLGLASKNAILIVEFAEAAYLRGEPLVAAAL
QGAATRLRPILMTSLAFIAGVMPLAMSTGAGANSRISIGSGIIGGTLTATVLAVFFVPLFFVLIRRVFSGKSKNITEHKG
V

Specific function: AcrAB is a drug efflux protein with a broad substrate specificity [H]

COG id: COG0841

COG function: function code V; Cation/multidrug efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AcrB/AcrD/AcrF (TC 2.A.6) family [H]

Homologues:

Organism=Escherichia coli, GI1786667, Length=1041, Percent_Identity=57.8290105667627, Blast_Score=1209, Evalue=0.0,
Organism=Escherichia coli, GI1789666, Length=1033, Percent_Identity=56.7279767666989, Blast_Score=1174, Evalue=0.0,
Organism=Escherichia coli, GI1788814, Length=1038, Percent_Identity=55.3949903660886, Blast_Score=1165, Evalue=0.0,
Organism=Escherichia coli, GI1789930, Length=1020, Percent_Identity=55.0980392156863, Blast_Score=1123, Evalue=0.0,
Organism=Escherichia coli, GI1788390, Length=1049, Percent_Identity=28.0266920877026, Blast_Score=372, Evalue=1e-104,
Organism=Escherichia coli, GI1788391, Length=1060, Percent_Identity=29.9056603773585, Blast_Score=370, Evalue=1e-103,
Organism=Escherichia coli, GI1786788, Length=1064, Percent_Identity=24.1541353383459, Blast_Score=241, Evalue=1e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001036
- InterPro:   IPR004764 [H]

Pfam domain/function: PF00873 ACR_tran [H]

EC number: NA

Molecular weight: Translated: 111995; Mature: 111995

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFARFFIYRPVFAWVIAIVIMLGGVVALETLPIAQYPDVAPPSISIKATYTGASAETLEN
CCCHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCEEEEEEECCCCHHHHHH
SVTQVIEQELTGLDGLLYFSSSSGSDGNAKIVATFKQGTNADTAQVQVQNKVQQALTRLP
HHHHHHHHHHCCCCEEEEEECCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCC
TEVQAQGVTVTKSQTNFLLIMSLYDEKDKHTGTDIADYLVSNLQDPLARLEGVGSVQVFG
CHHHHCCEEEEECCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEC
SQYAMRIWLNPTKLAAYNLMPSDVQSAITAQNTQVSAGKIGALPSGKEQQLTATVMAQSR
CCEEEEEEECCHHHHEECCCHHHHHHHHHHCCCEECCCCCCCCCCCCCHHHHHHHHHHHH
LKTPEQFNNIIVKSDSTGAVVRLRDVARVELGNEDYSVTTRLNGHPAAGIAVMLAPGANA
CCCCHHHCCEEEECCCCCCEEEEEHHHHEEECCCCEEEEEEECCCCCCCEEEEEECCCCH
LATAERVKAKAAEFELNLPDGYKIAYPKDSTDFIKVSVEEVVKTLIEAILLVVIVMYIFL
HHHHHHHHHHHHHEEEECCCCCEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHH
QNIRATLIPAIAVPVVLLGTFGVLAIFGYSINTLTLFGMVLSIGLLVDDAIVVVENVERV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MREDNLPPREATEKSMSEIASALIGIALVLSAVFLPMAFFGGATGVIYRQFSITIVSAMA
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHH
LSVLVALTLTPALCATFLKPNHKPPSEHGFFGGFNRRYDRMQTRYESLVGHVIHRSLRYL
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LIYAVLIGVMCVLFIRLPTGFLPTEDQGDVMVQYTLPAGATSGRTMEVSKAVENYFMTQE
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCEEHHHHHHHHHHCCCC
KDNTKAVFTISGFGFSGSGQNAGMAFIALKHWRDRPGSENTATAIADRAMKALSSIRDAQ
CCCCEEEEEEECCCCCCCCCCCCEEEEEEEHHCCCCCCCCHHHHHHHHHHHHHHHHCCCE
IFSMTPPAVDGLGQSNGFTFELQATGDTSREQLLTLRDQLISKANKDPILASVRANTLQQ
EEECCCCHHCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHH
MPQLQVDIDNDKAAALGLSISDVNATLSAAWGGTYINDFIDRGRVKKVYMQGDVDTRSKP
CCCEEEEECCCCCEEEEEEEECCCCHHHHHCCCHHHHHHHCCCCEEEEEEECCCCCCCCC
EDLNQWFVRGSSDAMTSFSAFATTRWIYGPETLSRYNGQTSYEIQGQAASGSSSGTAMDQ
HHHHHHHHCCCCHHHHHHHHHHHHEEEECCHHHHHCCCCEEEEEECCCCCCCCCCHHHHH
MEKLAAELPGTSYAWSGLSYQERLASGQALSLYAISILVVFLCLAALYESWSVPFSVMMV
HHHHHHHCCCCCEEECCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
IPLGIIGAVAAATLRGLENDIYFQVALLTTLGLASKNAILIVEFAEAAYLRGEPLVAAAL
HHHHHHHHHHHHHHHCCCCCHHEEEHHHHHHCCCCCCCEEEEEECCHHHHCCCCHHHHHH
QGAATRLRPILMTSLAFIAGVMPLAMSTGAGANSRISIGSGIIGGTLTATVLAVFFVPLF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHH
FVLIRRVFSGKSKNITEHKGV
HHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MFARFFIYRPVFAWVIAIVIMLGGVVALETLPIAQYPDVAPPSISIKATYTGASAETLEN
CCCHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCEEEEEEECCCCHHHHHH
SVTQVIEQELTGLDGLLYFSSSSGSDGNAKIVATFKQGTNADTAQVQVQNKVQQALTRLP
HHHHHHHHHHCCCCEEEEEECCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCC
TEVQAQGVTVTKSQTNFLLIMSLYDEKDKHTGTDIADYLVSNLQDPLARLEGVGSVQVFG
CHHHHCCEEEEECCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEC
SQYAMRIWLNPTKLAAYNLMPSDVQSAITAQNTQVSAGKIGALPSGKEQQLTATVMAQSR
CCEEEEEEECCHHHHEECCCHHHHHHHHHHCCCEECCCCCCCCCCCCCHHHHHHHHHHHH
LKTPEQFNNIIVKSDSTGAVVRLRDVARVELGNEDYSVTTRLNGHPAAGIAVMLAPGANA
CCCCHHHCCEEEECCCCCCEEEEEHHHHEEECCCCEEEEEEECCCCCCCEEEEEECCCCH
LATAERVKAKAAEFELNLPDGYKIAYPKDSTDFIKVSVEEVVKTLIEAILLVVIVMYIFL
HHHHHHHHHHHHHEEEECCCCCEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHH
QNIRATLIPAIAVPVVLLGTFGVLAIFGYSINTLTLFGMVLSIGLLVDDAIVVVENVERV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MREDNLPPREATEKSMSEIASALIGIALVLSAVFLPMAFFGGATGVIYRQFSITIVSAMA
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHH
LSVLVALTLTPALCATFLKPNHKPPSEHGFFGGFNRRYDRMQTRYESLVGHVIHRSLRYL
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LIYAVLIGVMCVLFIRLPTGFLPTEDQGDVMVQYTLPAGATSGRTMEVSKAVENYFMTQE
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCEEHHHHHHHHHHCCCC
KDNTKAVFTISGFGFSGSGQNAGMAFIALKHWRDRPGSENTATAIADRAMKALSSIRDAQ
CCCCEEEEEEECCCCCCCCCCCCEEEEEEEHHCCCCCCCCHHHHHHHHHHHHHHHHCCCE
IFSMTPPAVDGLGQSNGFTFELQATGDTSREQLLTLRDQLISKANKDPILASVRANTLQQ
EEECCCCHHCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHH
MPQLQVDIDNDKAAALGLSISDVNATLSAAWGGTYINDFIDRGRVKKVYMQGDVDTRSKP
CCCEEEEECCCCCEEEEEEEECCCCHHHHHCCCHHHHHHHCCCCEEEEEEECCCCCCCCC
EDLNQWFVRGSSDAMTSFSAFATTRWIYGPETLSRYNGQTSYEIQGQAASGSSSGTAMDQ
HHHHHHHHCCCCHHHHHHHHHHHHEEEECCHHHHHCCCCEEEEEECCCCCCCCCCHHHHH
MEKLAAELPGTSYAWSGLSYQERLASGQALSLYAISILVVFLCLAALYESWSVPFSVMMV
HHHHHHHCCCCCEEECCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
IPLGIIGAVAAATLRGLENDIYFQVALLTTLGLASKNAILIVEFAEAAYLRGEPLVAAAL
HHHHHHHHHHHHHHHCCCCCHHEEEHHHHHHCCCCCCCEEEEEECCHHHHCCCCHHHHHH
QGAATRLRPILMTSLAFIAGVMPLAMSTGAGANSRISIGSGIIGGTLTATVLAVFFVPLF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHH
FVLIRRVFSGKSKNITEHKGV
HHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; multidrug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + multidrug [Cytoplasm] = Proton [Cytoplasm] + multidrug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8407802; 9278503; 7651136; 10920254 [H]