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The map label for this gene is dppC [H]

Identifier: 153948735

GI number: 153948735

Start: 4589551

End: 4590453

Strand: Reverse

Name: dppC [H]

Synonym: YpsIP31758_4073

Alternate gene names: 153948735

Gene position: 4590453-4589551 (Counterclockwise)

Preceding gene: 153946908

Following gene: 153948539

Centisome position: 97.19

GC content: 54.04

Gene sequence:

>903_bases
ATGTCTCAACTTATTGAGTCAGCAGTAAAAAGTGCGCCGAAGCCAATGACGCCATTGCAGGAATTTTGGCACTATTTCAA
GCGCAATAAAGGGGCCGTGATCGGCTTGTTCTACATCATCATTATGCTGGTGGTTGCCGCAGGTGCAACCTGGTTGGCCC
CGCATGGTCCGGCAGAGCAATTTCGTGATGCGTTATTGAAGCCACCGGTTTGGGAAGAGGGTGGAAGCTGGAAATTTATT
TTAGGCACGGATGATGTTGGCCGTGATGTCCTCTCTCGCCTGATGTATGGCGCGCGCCTCTCTCTGTTAGTCGGGTGTTT
GGTGGTGGTGCTGTCATTGGTGATGGGCGTCATTTTTGGCTTATTGGCAGGTTATTTTGGCGGGATCGTTGATGCCATCA
TCATGCGTGTTGTTGATATCATGCTGGCGCTGCCAAGTCTGTTATTGGCCTTGGTTTTGGTTGCCGTGTTCGGGCCTTCT
ATCGTGAATGCCTCGTTGGCGCTGACGTTTGTGGCTTTGCCGCATTATGTGCGTCTGACGCGGGCGGCGGTGCTGGTTGA
GGTCAACCGAGATTACGTAACGGCATCAAGAGTGGCCGGTGCGGGTGCGATGCGCCAAATGTTCATCAACATTCTACCAA
ATTGCCTGGCACCGTTAATCGTGCAGGCTTCTCTCGGCTTCTCTAACGCCATTCTGGATATGGCGGCTCTCGGCTTTCTC
GGCATGGGCGCACAACCGCCAACACCAGAGTGGGGCACTATGCTCTCCGACGTGTTGCAGTTCGCGCAAAGTGCCTGGTG
GGTTGTGACCTTCCCCGGTGTGGCGATCCTGCTAACAGTTCTGGCGTTTAACCTGATGGGGGACGGCCTGCGTGATGCTC
TCGACCCCAAACTCAAGCAGTAA

Upstream 100 bases:

>100_bases
TTGCTGGTCGCGATCATGATTATTTTAGTTAACTTGCTGGTAGATGTGCTCTATGGCGTAGTTAACCCGCGTATTCGTCA
CAAGAAATAAGGGGCGCAGA

Downstream 100 bases:

>100_bases
CAGAGGTAGAGAGATGGCACTTTTAAATGTAGATAAATTGTCGGTGCATTTTGGTGACGACGCTGCGCCGTTCAAGGCCG
TAGATCGTATCAGTTACAGC

Product: dipeptide transporter

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MSQLIESAVKSAPKPMTPLQEFWHYFKRNKGAVIGLFYIIIMLVVAAGATWLAPHGPAEQFRDALLKPPVWEEGGSWKFI
LGTDDVGRDVLSRLMYGARLSLLVGCLVVVLSLVMGVIFGLLAGYFGGIVDAIIMRVVDIMLALPSLLLALVLVAVFGPS
IVNASLALTFVALPHYVRLTRAAVLVEVNRDYVTASRVAGAGAMRQMFINILPNCLAPLIVQASLGFSNAILDMAALGFL
GMGAQPPTPEWGTMLSDVLQFAQSAWWVVTFPGVAILLTVLAFNLMGDGLRDALDPKLKQ

Sequences:

>Translated_300_residues
MSQLIESAVKSAPKPMTPLQEFWHYFKRNKGAVIGLFYIIIMLVVAAGATWLAPHGPAEQFRDALLKPPVWEEGGSWKFI
LGTDDVGRDVLSRLMYGARLSLLVGCLVVVLSLVMGVIFGLLAGYFGGIVDAIIMRVVDIMLALPSLLLALVLVAVFGPS
IVNASLALTFVALPHYVRLTRAAVLVEVNRDYVTASRVAGAGAMRQMFINILPNCLAPLIVQASLGFSNAILDMAALGFL
GMGAQPPTPEWGTMLSDVLQFAQSAWWVVTFPGVAILLTVLAFNLMGDGLRDALDPKLKQ
>Mature_299_residues
SQLIESAVKSAPKPMTPLQEFWHYFKRNKGAVIGLFYIIIMLVVAAGATWLAPHGPAEQFRDALLKPPVWEEGGSWKFIL
GTDDVGRDVLSRLMYGARLSLLVGCLVVVLSLVMGVIFGLLAGYFGGIVDAIIMRVVDIMLALPSLLLALVLVAVFGPSI
VNASLALTFVALPHYVRLTRAAVLVEVNRDYVTASRVAGAGAMRQMFINILPNCLAPLIVQASLGFSNAILDMAALGFLG
MGAQPPTPEWGTMLSDVLQFAQSAWWVVTFPGVAILLTVLAFNLMGDGLRDALDPKLKQ

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789964, Length=300, Percent_Identity=88, Blast_Score=461, Evalue=1e-131,
Organism=Escherichia coli, GI1787760, Length=259, Percent_Identity=46.7181467181467, Blast_Score=220, Evalue=8e-59,
Organism=Escherichia coli, GI1787054, Length=283, Percent_Identity=40.9893992932862, Blast_Score=220, Evalue=8e-59,
Organism=Escherichia coli, GI1787549, Length=288, Percent_Identity=39.9305555555556, Blast_Score=211, Evalue=6e-56,
Organism=Escherichia coli, GI1789889, Length=254, Percent_Identity=37.7952755905512, Blast_Score=147, Evalue=8e-37,
Organism=Escherichia coli, GI1787498, Length=281, Percent_Identity=34.5195729537367, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1788505, Length=218, Percent_Identity=33.4862385321101, Blast_Score=108, Evalue=5e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 32308; Mature: 32177

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQLIESAVKSAPKPMTPLQEFWHYFKRNKGAVIGLFYIIIMLVVAAGATWLAPHGPAEQ
CHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHCCCCCCHHH
FRDALLKPPVWEEGGSWKFILGTDDVGRDVLSRLMYGARLSLLVGCLVVVLSLVMGVIFG
HHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLAGYFGGIVDAIIMRVVDIMLALPSLLLALVLVAVFGPSIVNASLALTFVALPHYVRLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAAVLVEVNRDYVTASRVAGAGAMRQMFINILPNCLAPLIVQASLGFSNAILDMAALGFL
HHHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
GMGAQPPTPEWGTMLSDVLQFAQSAWWVVTFPGVAILLTVLAFNLMGDGLRDALDPKLKQ
CCCCCCCCCHHHHHHHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHCCHHHHHCCCCCCC
>Mature Secondary Structure 
SQLIESAVKSAPKPMTPLQEFWHYFKRNKGAVIGLFYIIIMLVVAAGATWLAPHGPAEQ
HHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHCCCCCCHHH
FRDALLKPPVWEEGGSWKFILGTDDVGRDVLSRLMYGARLSLLVGCLVVVLSLVMGVIFG
HHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLAGYFGGIVDAIIMRVVDIMLALPSLLLALVLVAVFGPSIVNASLALTFVALPHYVRLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAAVLVEVNRDYVTASRVAGAGAMRQMFINILPNCLAPLIVQASLGFSNAILDMAALGFL
HHHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
GMGAQPPTPEWGTMLSDVLQFAQSAWWVVTFPGVAILLTVLAFNLMGDGLRDALDPKLKQ
CCCCCCCCCHHHHHHHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]