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The map label for this gene is yieH [H]

Identifier: 153948522

GI number: 153948522

Start: 4698841

End: 4699509

Strand: Direct

Name: yieH [H]

Synonym: YpsIP31758_4162

Alternate gene names: 153948522

Gene position: 4698841-4699509 (Clockwise)

Preceding gene: 153949768

Following gene: 153947360

Centisome position: 99.48

GC content: 47.98

Gene sequence:

>669_bases
GTGAATCAGATTCAATGCGTCATGTTCGATTGCGATGGCACCTTGGTCGACAGCGAAGTCCTGTGTTGCCAGGCTTACGT
CCTAATGTTTGCTCACTACAATATTCACCTGTCGTTAGAAGAGGTGATTAAACGCTTTAAAGGCGTAAAACTGTATGAAA
TTGTTGGGATAATCTGTAAAGAATATGGATTAGACCAACCGATAGAGGTACTGGAAAAGCTTTACCGTGAAGAAGTTGCA
CGTTTATTCGATGCCGAATTACAGCCTATAGCCGGTGCGAAAGCGCTGTTAGAGCAAATCGTGTTACCCGTCTGCGTGGT
ATCCAACGGGCCAGTCAGCAAAATGCAGCACTCGCTTGGCCTAACCGGATTACTGCCATTCTTTGAGGACCGGCTTTATA
GCAGCTATGATATTCAGCGTTGGAAGCCTGATCCGGCTCTGATTTACCATGCCGCTGAACATATGCAGGTTGCCGCTGAG
CACTGTATTTTGATTGAAGATTCTGCCGCAGGTGCCCAGGCCGGGATTGCCGCCGGTATTCCGGTGTTTTATTACTGTGC
CGATCCGCACAACCAACCGATTAACCACCCGCTAGTGACTACTTTCACGGATATTCAGCAACTGCCTGATTTGTGGAAGG
AAAGAGGCTGGCATATCACCCGCGATTAA

Upstream 100 bases:

>100_bases
TATTAATTTTATTACTAACAGGCTAATAAACATCGCTTTATTTATTAGGATGGTTAGAGTGGGATTAACTGATGTCTATC
TTTTTTAAAGGATTAGTTGC

Downstream 100 bases:

>100_bases
TTTACCTGTAATCAATTAACTCGATTGCAGTGTTAGCTTGTTACACCACCAGCGCCATGAACGTGCCATGGCGCTTTGTT
TTTTAATGGCATGCTGTGGG

Product: 6-phosphogluconate phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MNQIQCVMFDCDGTLVDSEVLCCQAYVLMFAHYNIHLSLEEVIKRFKGVKLYEIVGIICKEYGLDQPIEVLEKLYREEVA
RLFDAELQPIAGAKALLEQIVLPVCVVSNGPVSKMQHSLGLTGLLPFFEDRLYSSYDIQRWKPDPALIYHAAEHMQVAAE
HCILIEDSAAGAQAGIAAGIPVFYYCADPHNQPINHPLVTTFTDIQQLPDLWKERGWHITRD

Sequences:

>Translated_222_residues
MNQIQCVMFDCDGTLVDSEVLCCQAYVLMFAHYNIHLSLEEVIKRFKGVKLYEIVGIICKEYGLDQPIEVLEKLYREEVA
RLFDAELQPIAGAKALLEQIVLPVCVVSNGPVSKMQHSLGLTGLLPFFEDRLYSSYDIQRWKPDPALIYHAAEHMQVAAE
HCILIEDSAAGAQAGIAAGIPVFYYCADPHNQPINHPLVTTFTDIQQLPDLWKERGWHITRD
>Mature_222_residues
MNQIQCVMFDCDGTLVDSEVLCCQAYVLMFAHYNIHLSLEEVIKRFKGVKLYEIVGIICKEYGLDQPIEVLEKLYREEVA
RLFDAELQPIAGAKALLEQIVLPVCVVSNGPVSKMQHSLGLTGLLPFFEDRLYSSYDIQRWKPDPALIYHAAEHMQVAAE
HCILIEDSAAGAQAGIAAGIPVFYYCADPHNQPINHPLVTTFTDIQQLPDLWKERGWHITRD

Specific function: Catalyzes the dephosphorylation of the artificial chromogenic substrate p-nitrophenyl phosphate (pNPP) and of the natural substrates phosphoenolpyruvate and AMP [H]

COG id: COG0637

COG function: function code R; Predicted phosphatase/phosphohexomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Escherichia coli, GI1790151, Length=220, Percent_Identity=62.7272727272727, Blast_Score=298, Evalue=2e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: NA

Molecular weight: Translated: 25088; Mature: 25088

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQIQCVMFDCDGTLVDSEVLCCQAYVLMFAHYNIHLSLEEVIKRFKGVKLYEIVGIICK
CCCEEEEEEECCCCEECHHHHHHHHHHHHHHHCCEEEEHHHHHHHHCCCHHHHHHHHHHH
EYGLDQPIEVLEKLYREEVARLFDAELQPIAGAKALLEQIVLPVCVVSNGPVSKMQHSLG
HCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHEECCCCHHHHHHHCC
LTGLLPFFEDRLYSSYDIQRWKPDPALIYHAAEHMQVAAEHCILIEDSAAGAQAGIAAGI
CHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCHHCCC
PVFYYCADPHNQPINHPLVTTFTDIQQLPDLWKERGWHITRD
CEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNQIQCVMFDCDGTLVDSEVLCCQAYVLMFAHYNIHLSLEEVIKRFKGVKLYEIVGIICK
CCCEEEEEEECCCCEECHHHHHHHHHHHHHHHCCEEEEHHHHHHHHCCCHHHHHHHHHHH
EYGLDQPIEVLEKLYREEVARLFDAELQPIAGAKALLEQIVLPVCVVSNGPVSKMQHSLG
HCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHEECCCCHHHHHHHCC
LTGLLPFFEDRLYSSYDIQRWKPDPALIYHAAEHMQVAAEHCILIEDSAAGAQAGIAAGI
CHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCHHCCC
PVFYYCADPHNQPINHPLVTTFTDIQQLPDLWKERGWHITRD
CEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]