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The map label for this gene is uvrD [C]

Identifier: 153948461

GI number: 153948461

Start: 968006

End: 969856

Strand: Direct

Name: uvrD [C]

Synonym: YpsIP31758_0807

Alternate gene names: 153948461

Gene position: 968006-969856 (Clockwise)

Preceding gene: 153948017

Following gene: 153949492

Centisome position: 20.49

GC content: 42.03

Gene sequence:

>1851_bases
ATGGCTGAGCTTATCCCTACACTAAATAGTTGCTCTGAAAAAATGACGCCTGGCGAGCGCCGCTTTGCAAAACGGATTGA
GGCTTCTCTCGGTAATGACTGTTTGTGTTGGTATGACATTCCTGTCGGGCGGCAAAGACGTTACCCTGATTTTATTATTC
TGAATCCAGAGCGTGGATTACTCTTCGTAGAAGTGAAGGATTGGAGAATTGAACATCTGCGGAAAATCAACAAAACCAGT
GTGCAATATTTCCATAATAATGAGCTTATAACCTTAACCAACCCGATTGAGCAGGTTCGTCAGTGCAGCTATGCTGTTAT
TAATCAGTTAAAAACAGACATGCAATTATTACAACAAGAGGAAAGATATAAAGGGGGGCTTTGTATGGCATATGGCTATG
GGGTTGTCTTTAGCCATATAACGCGTAAACAGTTAAATAGTGCCATTCCTGTCGATGAACAAATTAATATTCTTCCCCCT
AATTTAGTTATTTGTAGTGATGAAATAACTGATTCCATCAGTAGTGAGTTATTTAGTCATGCTCTTTGGGCATTATTTCC
CTATCAATTTAAAATGTCTCTAACGTCAGTTCAGCGTGACCGTATTCGTTGGCATCTTTTTCCTGAAATTCGCATTACAC
ACACCCAGACCGATCTTTTCCAGACAGATGAAATAAATGTTAATAAGGCGTCCTGTCAACCCATACCGGATATCATCCGG
ATCATGGATATCCAGCAAGAATTACTTGCCCGTAGTTTAGGGGAGGGACATCGCGTTATACACGGTGTTGCCGGTTCGGG
GAAAACGTTGATATTGCTGTATCGGTGTCTGTACCTTGCTGAAGTGCTCACAACGCCTATTTTAGTGCTCTGTTACAATA
TGACCTTAGCGGCCAGATTAAAATGCCAAATTGCTGAGCGAGGACTGGAAGAGAGAGTTCAGGTATTTCATTTTCATGGG
TGGTGTAAAGATCAATGTCAAAAATATAACGTTAACGTGAAAGCCTTGGAGGGCAACCCTTGGGAGTTACATGTTGAGGC
TGTTATTGATGCAGTGAACGGGGGCATTATCCCGAAGGAACAATATGGTGCTGTCTTGATCGACGAAGGGCATGATTTTG
ATTCTACCTGGCTAGCATTAGTCTCTCAGATGGTGGATACAAAAACGAATGCGCTCCTGTTCATGTATGACGATGCCCAA
TCTATTTACAGAAAACGTGGGGCATTAAGTTTCTCCCTAGCCAGTGTGGGTATTCAAGCCCAAGGACGAACATCTATATT
GCGGCTGAATTACCGCAATACTAAAGAGATCCTCGCATTTTCTTATATATTTGCACAGCAACATTTTGATTCACGTGATG
ATTCACATACAGCGTTTATGCCACCAGAGTCCGCTGGCCCGCAAGGTATCCCTCCCGAGTTAAAATCATTTGAATCATTA
TCAAAAGAAGTTTTTCATCTTATTTCATGGATCAAAAATGAGCATTCTAACGGCGTTTGTTGGCGGGATATCGCTATTCT
TTGTCCTTCTAACGGAGTGGGTAAATACCTGGAAATAGCACTTGTGAATACAGATATCCCTCACGCCCATCTTTTCACTG
CGAACGATAAAAAGAGATATAACCCGTCAAATGATAAAGTGTGTATTTTACCTTTACCTAGCAGTAAGGGATTAGAGTTT
CACTCAGTGGCGGTTATCGACAGCAGCCATATACTCAATGATGGCCTGGATTTAGCTGATGAGGTCCGTCGCTTATATGT
CGGATTTACACGAGCGACTCAGCATTTGCTTGTTACATGGCATAAAAATAATGCGCTCAGCACCAGTCTGAAGAAAGTCA
TACAACAGTGA

Upstream 100 bases:

>100_bases
AAGATTAAGAAAACATAACAATATGATTTCTAAGTAAGCTTCTCTTACCAACATTGCCTTACCGTAATGAGTATTTTTCT
AATGACTTCACAGGACCCGT

Downstream 100 bases:

>100_bases
TGGTTATCGTCACAAGCAGCGTAACTCACGGTGTTTAATGCATTGCGCCAGGCGTTGCAAGTGGTACATGGTATATTGAG
TGGTAGTGTTTGTTATCAAA

Product: hypothetical protein

Products: NA

Alternate protein names: LexA Repressor; NERD Domain Protein; DNA Helicase; NERD Domain-Containing Protein; UvrD/REP Helicase; Superfamily I DNA/RNA Helicase-Like Protein; UvrD/REP Helicase Domain Protein; Superfamily I DNA And RNA Helicase; Helicase Protein; DNA/RNA Helicase Superfamily I; Helicase Family Protein; Uvrd/Rep Helicase; DNA Helicase II Related Protein

Number of amino acids: Translated: 616; Mature: 615

Protein sequence:

>616_residues
MAELIPTLNSCSEKMTPGERRFAKRIEASLGNDCLCWYDIPVGRQRRYPDFIILNPERGLLFVEVKDWRIEHLRKINKTS
VQYFHNNELITLTNPIEQVRQCSYAVINQLKTDMQLLQQEERYKGGLCMAYGYGVVFSHITRKQLNSAIPVDEQINILPP
NLVICSDEITDSISSELFSHALWALFPYQFKMSLTSVQRDRIRWHLFPEIRITHTQTDLFQTDEINVNKASCQPIPDIIR
IMDIQQELLARSLGEGHRVIHGVAGSGKTLILLYRCLYLAEVLTTPILVLCYNMTLAARLKCQIAERGLEERVQVFHFHG
WCKDQCQKYNVNVKALEGNPWELHVEAVIDAVNGGIIPKEQYGAVLIDEGHDFDSTWLALVSQMVDTKTNALLFMYDDAQ
SIYRKRGALSFSLASVGIQAQGRTSILRLNYRNTKEILAFSYIFAQQHFDSRDDSHTAFMPPESAGPQGIPPELKSFESL
SKEVFHLISWIKNEHSNGVCWRDIAILCPSNGVGKYLEIALVNTDIPHAHLFTANDKKRYNPSNDKVCILPLPSSKGLEF
HSVAVIDSSHILNDGLDLADEVRRLYVGFTRATQHLLVTWHKNNALSTSLKKVIQQ

Sequences:

>Translated_616_residues
MAELIPTLNSCSEKMTPGERRFAKRIEASLGNDCLCWYDIPVGRQRRYPDFIILNPERGLLFVEVKDWRIEHLRKINKTS
VQYFHNNELITLTNPIEQVRQCSYAVINQLKTDMQLLQQEERYKGGLCMAYGYGVVFSHITRKQLNSAIPVDEQINILPP
NLVICSDEITDSISSELFSHALWALFPYQFKMSLTSVQRDRIRWHLFPEIRITHTQTDLFQTDEINVNKASCQPIPDIIR
IMDIQQELLARSLGEGHRVIHGVAGSGKTLILLYRCLYLAEVLTTPILVLCYNMTLAARLKCQIAERGLEERVQVFHFHG
WCKDQCQKYNVNVKALEGNPWELHVEAVIDAVNGGIIPKEQYGAVLIDEGHDFDSTWLALVSQMVDTKTNALLFMYDDAQ
SIYRKRGALSFSLASVGIQAQGRTSILRLNYRNTKEILAFSYIFAQQHFDSRDDSHTAFMPPESAGPQGIPPELKSFESL
SKEVFHLISWIKNEHSNGVCWRDIAILCPSNGVGKYLEIALVNTDIPHAHLFTANDKKRYNPSNDKVCILPLPSSKGLEF
HSVAVIDSSHILNDGLDLADEVRRLYVGFTRATQHLLVTWHKNNALSTSLKKVIQQ
>Mature_615_residues
AELIPTLNSCSEKMTPGERRFAKRIEASLGNDCLCWYDIPVGRQRRYPDFIILNPERGLLFVEVKDWRIEHLRKINKTSV
QYFHNNELITLTNPIEQVRQCSYAVINQLKTDMQLLQQEERYKGGLCMAYGYGVVFSHITRKQLNSAIPVDEQINILPPN
LVICSDEITDSISSELFSHALWALFPYQFKMSLTSVQRDRIRWHLFPEIRITHTQTDLFQTDEINVNKASCQPIPDIIRI
MDIQQELLARSLGEGHRVIHGVAGSGKTLILLYRCLYLAEVLTTPILVLCYNMTLAARLKCQIAERGLEERVQVFHFHGW
CKDQCQKYNVNVKALEGNPWELHVEAVIDAVNGGIIPKEQYGAVLIDEGHDFDSTWLALVSQMVDTKTNALLFMYDDAQS
IYRKRGALSFSLASVGIQAQGRTSILRLNYRNTKEILAFSYIFAQQHFDSRDDSHTAFMPPESAGPQGIPPELKSFESLS
KEVFHLISWIKNEHSNGVCWRDIAILCPSNGVGKYLEIALVNTDIPHAHLFTANDKKRYNPSNDKVCILPLPSSKGLEFH
SVAVIDSSHILNDGLDLADEVRRLYVGFTRATQHLLVTWHKNNALSTSLKKVIQQ

Specific function: Has Both Atpase And Helicase Activities. Unwinds DNA Duplexes With 3' To 5' Polarity With Respect To The Bound Strand And Initiates Unwinding Most Effectively When A Single-Stranded Region Is Present. Involved In The Post-Incision Events Of Nucleotide Exc

COG id: COG0210

COG function: function code L; Superfamily I DNA and RNA helicases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: 3000 [C]

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.6.1.- [C]

Molecular weight: Translated: 70196; Mature: 70065

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAELIPTLNSCSEKMTPGERRFAKRIEASLGNDCLCWYDIPVGRQRRYPDFIILNPERGL
CCCCCCCHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEEECCCCCE
LFVEVKDWRIEHLRKINKTSVQYFHNNELITLTNPIEQVRQCSYAVINQLKTDMQLLQQE
EEEEECCHHHHHHHHHCHHHEEEEECCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
ERYKGGLCMAYGYGVVFSHITRKQLNSAIPVDEQINILPPNLVICSDEITDSISSELFSH
HHHCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCCEECCCCEEEECHHHHHHHHHHHHHH
ALWALFPYQFKMSLTSVQRDRIRWHLFPEIRITHTQTDLFQTDEINVNKASCQPIPDIIR
HHHHHHHHHHHHHHHHHHHHCEEEEECCCEEEEECCCCCEECCCCCCCCCCCCCHHHHHH
IMDIQQELLARSLGEGHRVIHGVAGSGKTLILLYRCLYLAEVLTTPILVLCYNMTLAARL
HHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
KCQIAERGLEERVQVFHFHGWCKDQCQKYNVNVKALEGNPWELHVEAVIDAVNGGIIPKE
HHHHHHCCHHHHHHEEEECCCCHHHHHEECCEEEEECCCCCEEEHHHHHHHHCCCCCCCH
QYGAVLIDEGHDFDSTWLALVSQMVDTKTNALLFMYDDAQSIYRKRGALSFSLASVGIQA
HCCEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHCCCCEEEEHHCCEEE
QGRTSILRLNYRNTKEILAFSYIFAQQHFDSRDDSHTAFMPPESAGPQGIPPELKSFESL
CCCEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHH
SKEVFHLISWIKNEHSNGVCWRDIAILCPSNGVGKYLEIALVNTDIPHAHLFTANDKKRY
HHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCCEEEEEEEECCCCCEEEEECCCCCCC
NPSNDKVCILPLPSSKGLEFHSVAVIDSSHILNDGLDLADEVRRLYVGFTRATQHLLVTW
CCCCCCEEEEECCCCCCCCEEEEEEEECCHHHCCCCCHHHHHHHHHHHHHHCCEEEEEEE
HKNNALSTSLKKVIQQ
ECCCCHHHHHHHHHCC
>Mature Secondary Structure 
AELIPTLNSCSEKMTPGERRFAKRIEASLGNDCLCWYDIPVGRQRRYPDFIILNPERGL
CCCCCCHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEEECCCCCE
LFVEVKDWRIEHLRKINKTSVQYFHNNELITLTNPIEQVRQCSYAVINQLKTDMQLLQQE
EEEEECCHHHHHHHHHCHHHEEEEECCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
ERYKGGLCMAYGYGVVFSHITRKQLNSAIPVDEQINILPPNLVICSDEITDSISSELFSH
HHHCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCCEECCCCEEEECHHHHHHHHHHHHHH
ALWALFPYQFKMSLTSVQRDRIRWHLFPEIRITHTQTDLFQTDEINVNKASCQPIPDIIR
HHHHHHHHHHHHHHHHHHHHCEEEEECCCEEEEECCCCCEECCCCCCCCCCCCCHHHHHH
IMDIQQELLARSLGEGHRVIHGVAGSGKTLILLYRCLYLAEVLTTPILVLCYNMTLAARL
HHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
KCQIAERGLEERVQVFHFHGWCKDQCQKYNVNVKALEGNPWELHVEAVIDAVNGGIIPKE
HHHHHHCCHHHHHHEEEECCCCHHHHHEECCEEEEECCCCCEEEHHHHHHHHCCCCCCCH
QYGAVLIDEGHDFDSTWLALVSQMVDTKTNALLFMYDDAQSIYRKRGALSFSLASVGIQA
HCCEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHCCCCEEEEHHCCEEE
QGRTSILRLNYRNTKEILAFSYIFAQQHFDSRDDSHTAFMPPESAGPQGIPPELKSFESL
CCCEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHH
SKEVFHLISWIKNEHSNGVCWRDIAILCPSNGVGKYLEIALVNTDIPHAHLFTANDKKRY
HHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCCEEEEEEEECCCCCEEEEECCCCCCC
NPSNDKVCILPLPSSKGLEFHSVAVIDSSHILNDGLDLADEVRRLYVGFTRATQHLLVTW
CCCCCCEEEEECCCCCCCCEEEEEEEECCHHHCCCCCHHHHHHHHHHHHHHCCEEEEEEE
HKNNALSTSLKKVIQQ
ECCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: Hydrolase; In phosphorus-containing anhydrides [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA