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The map label for this gene is pdxY

Identifier: 153948352

GI number: 153948352

Start: 2050915

End: 2051775

Strand: Direct

Name: pdxY

Synonym: YpsIP31758_1774

Alternate gene names: 153948352

Gene position: 2050915-2051775 (Clockwise)

Preceding gene: 153948792

Following gene: 153950872

Centisome position: 43.42

GC content: 50.29

Gene sequence:

>861_bases
ATGAAAAATATACTTTCTATTCAGTCACACGTCGTTTTTGGCCACGCAGGGAATAGCGCTGCAGAATTTCCTATGCGTCG
TATGGGGGTGAATGTCTGGCCGCTGAATACCGTTCAGTTTTCGAATCATACTCAATATGGTCACTGGACAGGTTGTGTCA
TGCCCGCTAGCCATTTAACTGACATTGTGCAAGGCATTGCCGATATCGATCGACTGAAAGACTGTGATGCGGTTCTGAGT
GGCTATATTGGGTCGCCAGAACAGGGCAGTCATATTCTGGCCGCCGTCGCCCAGGTTAAACAAGCCAATCCAGATGCTTG
GTATTTTTGTGATCCGGTCATGGGGCACCCCGAAAAAGGGTGTATTGTGGCACCGGGGGTGGCCGAATTTTTCTGCAACG
AAGCTTTGCCTGCCAGTGATATGATTGCGCCGAACCTGCTTGAACTTGAGCAACTCAGTGGTGAGCGAGTAGAGAATGTC
GAACAGGCGGTACAGGTTGCCCGTTCTCTTTGCGCTAGGGGGCCAAAAGTCGTGTTAGTCAAGCACCTGAGCCGTGCAGG
CTACCATGCTGACTGCTTCGAAATGTTATTGGTTACCGCAGATGATGCCTGGCATATCTGCCGCCCGCTGGTGGATTTTG
GCAAACGTCAACCGGTTGGTGTCGGTGATTTAACCAGTGGTTTATTGCTGGTGAATTTGTTGAAAGGTGAGCCATTGGAT
AAAGCACTGGAACATGTCACCGCCGCCGTGTATGAAGTGATGCTCAAAACACAGGAAATGGGGGAGTATGAGCTACAGGT
TGTCGCTGCCCAAGAGACTATTGTGACGCCTATCTGCCAGTTTACAGCGGTTAGGCTGTAA

Upstream 100 bases:

>100_bases
CTCTTTTAAGTCAGTGATTCGTGTGAGCGAAAACGGCTAACACCGCTGCAACTTTATGTAAGAAGGGTATACCAAACGCC
CTTAACTTTAGGCCGTACCA

Downstream 100 bases:

>100_bases
TCTAACCATTTTCAATTGCCCCCTAGTGATGGGGGCAATTGATTGATTCTCATTATTTATTACTTGATATCTTCGGCGGC
TAAAGCTGCTTTTACCGCAG

Product: pyridoxamine kinase

Products: NA

Alternate protein names: PM kinase

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MKNILSIQSHVVFGHAGNSAAEFPMRRMGVNVWPLNTVQFSNHTQYGHWTGCVMPASHLTDIVQGIADIDRLKDCDAVLS
GYIGSPEQGSHILAAVAQVKQANPDAWYFCDPVMGHPEKGCIVAPGVAEFFCNEALPASDMIAPNLLELEQLSGERVENV
EQAVQVARSLCARGPKVVLVKHLSRAGYHADCFEMLLVTADDAWHICRPLVDFGKRQPVGVGDLTSGLLLVNLLKGEPLD
KALEHVTAAVYEVMLKTQEMGEYELQVVAAQETIVTPICQFTAVRL

Sequences:

>Translated_286_residues
MKNILSIQSHVVFGHAGNSAAEFPMRRMGVNVWPLNTVQFSNHTQYGHWTGCVMPASHLTDIVQGIADIDRLKDCDAVLS
GYIGSPEQGSHILAAVAQVKQANPDAWYFCDPVMGHPEKGCIVAPGVAEFFCNEALPASDMIAPNLLELEQLSGERVENV
EQAVQVARSLCARGPKVVLVKHLSRAGYHADCFEMLLVTADDAWHICRPLVDFGKRQPVGVGDLTSGLLLVNLLKGEPLD
KALEHVTAAVYEVMLKTQEMGEYELQVVAAQETIVTPICQFTAVRL
>Mature_286_residues
MKNILSIQSHVVFGHAGNSAAEFPMRRMGVNVWPLNTVQFSNHTQYGHWTGCVMPASHLTDIVQGIADIDRLKDCDAVLS
GYIGSPEQGSHILAAVAQVKQANPDAWYFCDPVMGHPEKGCIVAPGVAEFFCNEALPASDMIAPNLLELEQLSGERVENV
EQAVQVARSLCARGPKVVLVKHLSRAGYHADCFEMLLVTADDAWHICRPLVDFGKRQPVGVGDLTSGLLLVNLLKGEPLD
KALEHVTAAVYEVMLKTQEMGEYELQVVAAQETIVTPICQFTAVRL

Specific function: Phosphorylates B6 vitamers; functions in a salvage pathway. Uses pyridoxamine

COG id: COG2240

COG function: function code H; Pyridoxal/pyridoxine/pyridoxamine kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxine kinase family

Homologues:

Organism=Homo sapiens, GI4505701, Length=180, Percent_Identity=36.1111111111111, Blast_Score=129, Evalue=4e-30,
Organism=Escherichia coli, GI1787924, Length=286, Percent_Identity=75.1748251748252, Blast_Score=444, Evalue=1e-126,
Organism=Escherichia coli, GI1788758, Length=263, Percent_Identity=31.1787072243346, Blast_Score=123, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17507759, Length=268, Percent_Identity=30.9701492537313, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17507757, Length=278, Percent_Identity=30.2158273381295, Blast_Score=108, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6324354, Length=275, Percent_Identity=30.5454545454545, Blast_Score=100, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6320806, Length=242, Percent_Identity=32.6446280991736, Blast_Score=99, Evalue=7e-22,
Organism=Drosophila melanogaster, GI45553007, Length=303, Percent_Identity=30.3630363036304, Blast_Score=125, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PDXY_YERPA (Q1C792)

Other databases:

- EMBL:   CP000308
- RefSeq:   YP_651625.1
- ProteinModelPortal:   Q1C792
- SMR:   Q1C792
- STRING:   Q1C792
- GeneID:   4121608
- GenomeReviews:   CP000308_GR
- KEGG:   ypa:YPA_1714
- eggNOG:   COG2240
- HOGENOM:   HBG661459
- OMA:   CPNQLEL
- ProtClustDB:   PRK05756
- BioCyc:   YPES360102:YPA_1714-MONOMER
- HAMAP:   MF_01639
- InterPro:   IPR013749
- InterPro:   IPR004625
- TIGRFAMs:   TIGR00687

Pfam domain/function: PF08543 Phos_pyr_kin

EC number: =2.7.1.35

Molecular weight: Translated: 31185; Mature: 31185

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: BINDING 9-9 BINDING 44-44 BINDING 223-223

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNILSIQSHVVFGHAGNSAAEFPMRRMGVNVWPLNTVQFSNHTQYGHWTGCVMPASHLT
CCCHHHHHHEEEEECCCCCHHHCCHHHHCCCEECCCEEEECCCCCCCCCCCCCCCHHHHH
DIVQGIADIDRLKDCDAVLSGYIGSPEQGSHILAAVAQVKQANPDAWYFCDPVMGHPEKG
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCC
CIVAPGVAEFFCNEALPASDMIAPNLLELEQLSGERVENVEQAVQVARSLCARGPKVVLV
CEECCCHHHHHHCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEHH
KHLSRAGYHADCFEMLLVTADDAWHICRPLVDFGKRQPVGVGDLTSGLLLVNLLKGEPLD
HHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCHH
KALEHVTAAVYEVMLKTQEMGEYELQVVAAQETIVTPICQFTAVRL
HHHHHHHHHHHHHHHHHHHCCCEEEEEEEHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKNILSIQSHVVFGHAGNSAAEFPMRRMGVNVWPLNTVQFSNHTQYGHWTGCVMPASHLT
CCCHHHHHHEEEEECCCCCHHHCCHHHHCCCEECCCEEEECCCCCCCCCCCCCCCHHHHH
DIVQGIADIDRLKDCDAVLSGYIGSPEQGSHILAAVAQVKQANPDAWYFCDPVMGHPEKG
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCC
CIVAPGVAEFFCNEALPASDMIAPNLLELEQLSGERVENVEQAVQVARSLCARGPKVVLV
CEECCCHHHHHHCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEHH
KHLSRAGYHADCFEMLLVTADDAWHICRPLVDFGKRQPVGVGDLTSGLLLVNLLKGEPLD
HHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCHH
KALEHVTAAVYEVMLKTQEMGEYELQVVAAQETIVTPICQFTAVRL
HHHHHHHHHHHHHHHHHHHCCCEEEEEEEHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA