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The map label for this gene is intZ [H]

Identifier: 153948267

GI number: 153948267

Start: 61537

End: 62805

Strand: Reverse

Name: intZ [H]

Synonym: YpsIP31758_0054

Alternate gene names: 153948267

Gene position: 62805-61537 (Counterclockwise)

Preceding gene: 153947343

Following gene: 153948831

Centisome position: 1.33

GC content: 49.57

Gene sequence:

>1269_bases
ATGGCAAAACTCACAGACATGCAGATCCGGGCTTGGATCAAGGCCGGAGAACGATTTGAAGGCCGGGCAGATGGCAATGG
GCTGTATCTGCGACACAGGGAAGCTGACAGATCACCAAGCTGGCGTTTCCGCTATAAGTTCTCTGGTAAGTCCCGCATCA
TGCTCATTGGTTCATATTCTGAGATATCACTGTCCAAAGCCCGTGACATAGTAAAAGAGCTATCAGCACGTGTATCGCTT
GGCTATGACGTTGCCGGAGAGAAGCAGGAACGGAAAGCCGAAGCACTGGAGAAGATGGAAGCCGAAAAGAACGCCATGCG
CGTTTCAGAGCTTGCCGCTGAATACTTTGAGCGCCAGATCCTACCTCGCTGGAAGCACCCCGATATACTCCGCAGGCGCA
TAGATAAAGATATTAATCCGCATATCGGCAGTATGAAATTAGAGGATGTGAAGCCGCGTAACATTGACGACATGCTAAAG
GCCATAGTTGACCGTGGAGCACCAACTATAGCCACGGATGTTCTACGCTGGACACGTCGCATATTCGATTACGGTATCAA
GCGCCACGCATTAGAAGTCAACCCATGTTCAGCCTTTGAGGTGGCAGACGCTGGTGGAAAAGAAGTGAGCCGCGATCGCT
GGCTAACTCGTGATGAATTAATCCGGTTATTTCAGGCTATGCGCATGGCTAAAGGATTCAGCCGTCAGAATGAAATAACA
TTTAAGTTATTGTTGGCTCTATGCGTGCGAAAAATGGAGCTATGCGCCGCCCGTTGGGAAGAATTCGATCTCGACGCTGC
TATATGGCATTTACCAGCAGAGCGTAGTAAAAATGGTGACGCTATCGATATTCCATTACCACCACCAGCGGTTGAGTGGC
TTAAAGAGCTTCATACATTCTCATGCAACAGTGCGTGGGTACTGCCAGCCAGAAAAATGCAAAACAGAATGATTCCCCAC
ATCCAAGAAAGCACATTACCCGTGGCGTTAGCTAAGGTTCGGGCAGAAATGCCAGACGTTGAAAATATCACTATTCACGA
CTTCCGACGCACTGCCCGTACACATTTAGCCGCACTAGGTGTTGACCCTGTAGTAGCTGAACGCTGCCTAAATCACCGGA
TAAAGGGTGTTGAGGGCATTTACAACCGGCACCAATACTTTGACGAACGTAAAGCGGCGCTGGCGCAGTGGGTGGGCTTG
CTGGTGGCGCTAGAGAGGGGTGAGGATTACAATGTTACTCCTATCAACAAGACGCACAAAACAGCATAA

Upstream 100 bases:

>100_bases
CATTAAAGCGCATGATTGCCGTGTACACAAAGGTGTACCCAATGAGTTTTGTGTACATCACTTTGGGTACACCCTTCTAT
TCAATGTTCAGGTGGTCGTT

Downstream 100 bases:

>100_bases
AAGAACAGATTGAGCCTAGCCTGACGGGGCGAAAAGCGGAAAGCCTTACCGCCTGGCTCAATCTACTATTTAAGGTATAG
CGCAAAAGGTGACGCTGTGA

Product: phage integrase family site specific recombinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 422; Mature: 421

Protein sequence:

>422_residues
MAKLTDMQIRAWIKAGERFEGRADGNGLYLRHREADRSPSWRFRYKFSGKSRIMLIGSYSEISLSKARDIVKELSARVSL
GYDVAGEKQERKAEALEKMEAEKNAMRVSELAAEYFERQILPRWKHPDILRRRIDKDINPHIGSMKLEDVKPRNIDDMLK
AIVDRGAPTIATDVLRWTRRIFDYGIKRHALEVNPCSAFEVADAGGKEVSRDRWLTRDELIRLFQAMRMAKGFSRQNEIT
FKLLLALCVRKMELCAARWEEFDLDAAIWHLPAERSKNGDAIDIPLPPPAVEWLKELHTFSCNSAWVLPARKMQNRMIPH
IQESTLPVALAKVRAEMPDVENITIHDFRRTARTHLAALGVDPVVAERCLNHRIKGVEGIYNRHQYFDERKAALAQWVGL
LVALERGEDYNVTPINKTHKTA

Sequences:

>Translated_422_residues
MAKLTDMQIRAWIKAGERFEGRADGNGLYLRHREADRSPSWRFRYKFSGKSRIMLIGSYSEISLSKARDIVKELSARVSL
GYDVAGEKQERKAEALEKMEAEKNAMRVSELAAEYFERQILPRWKHPDILRRRIDKDINPHIGSMKLEDVKPRNIDDMLK
AIVDRGAPTIATDVLRWTRRIFDYGIKRHALEVNPCSAFEVADAGGKEVSRDRWLTRDELIRLFQAMRMAKGFSRQNEIT
FKLLLALCVRKMELCAARWEEFDLDAAIWHLPAERSKNGDAIDIPLPPPAVEWLKELHTFSCNSAWVLPARKMQNRMIPH
IQESTLPVALAKVRAEMPDVENITIHDFRRTARTHLAALGVDPVVAERCLNHRIKGVEGIYNRHQYFDERKAALAQWVGL
LVALERGEDYNVTPINKTHKTA
>Mature_421_residues
AKLTDMQIRAWIKAGERFEGRADGNGLYLRHREADRSPSWRFRYKFSGKSRIMLIGSYSEISLSKARDIVKELSARVSLG
YDVAGEKQERKAEALEKMEAEKNAMRVSELAAEYFERQILPRWKHPDILRRRIDKDINPHIGSMKLEDVKPRNIDDMLKA
IVDRGAPTIATDVLRWTRRIFDYGIKRHALEVNPCSAFEVADAGGKEVSRDRWLTRDELIRLFQAMRMAKGFSRQNEITF
KLLLALCVRKMELCAARWEEFDLDAAIWHLPAERSKNGDAIDIPLPPPAVEWLKELHTFSCNSAWVLPARKMQNRMIPHI
QESTLPVALAKVRAEMPDVENITIHDFRRTARTHLAALGVDPVVAERCLNHRIKGVEGIYNRHQYFDERKAALAQWVGLL
VALERGEDYNVTPINKTHKTA

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI145693166, Length=380, Percent_Identity=26.3157894736842, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1788974, Length=413, Percent_Identity=26.8765133171913, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1788690, Length=405, Percent_Identity=26.9135802469136, Blast_Score=96, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 48630; Mature: 48499

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKLTDMQIRAWIKAGERFEGRADGNGLYLRHREADRSPSWRFRYKFSGKSRIMLIGSYS
CCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCEEEEEEECCCCEEEEEECCC
EISLSKARDIVKELSARVSLGYDVAGEKQERKAEALEKMEAEKNAMRVSELAAEYFERQI
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPRWKHPDILRRRIDKDINPHIGSMKLEDVKPRNIDDMLKAIVDRGAPTIATDVLRWTRR
CCCCCCHHHHHHHHCCCCCCCCCCEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHH
IFDYGIKRHALEVNPCSAFEVADAGGKEVSRDRWLTRDELIRLFQAMRMAKGFSRQNEIT
HHHHHHHHCEEECCCCCCEEECCCCCCHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHH
FKLLLALCVRKMELCAARWEEFDLDAAIWHLPAERSKNGDAIDIPLPPPAVEWLKELHTF
HHHHHHHHHHHHHHHHHHHHHCCCCHHHEECCCCCCCCCCEEECCCCCHHHHHHHHHHHC
SCNSAWVLPARKMQNRMIPHIQESTLPVALAKVRAEMPDVENITIHDFRRTARTHLAALG
CCCCEEECCHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHC
VDPVVAERCLNHRIKGVEGIYNRHQYFDERKAALAQWVGLLVALERGEDYNVTPINKTHK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
TA
CC
>Mature Secondary Structure 
AKLTDMQIRAWIKAGERFEGRADGNGLYLRHREADRSPSWRFRYKFSGKSRIMLIGSYS
CCCCHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCEEEEEEECCCCEEEEEECCC
EISLSKARDIVKELSARVSLGYDVAGEKQERKAEALEKMEAEKNAMRVSELAAEYFERQI
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPRWKHPDILRRRIDKDINPHIGSMKLEDVKPRNIDDMLKAIVDRGAPTIATDVLRWTRR
CCCCCCHHHHHHHHCCCCCCCCCCEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHH
IFDYGIKRHALEVNPCSAFEVADAGGKEVSRDRWLTRDELIRLFQAMRMAKGFSRQNEIT
HHHHHHHHCEEECCCCCCEEECCCCCCHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHH
FKLLLALCVRKMELCAARWEEFDLDAAIWHLPAERSKNGDAIDIPLPPPAVEWLKELHTF
HHHHHHHHHHHHHHHHHHHHHCCCCHHHEECCCCCCCCCCEEECCCCCHHHHHHHHHHHC
SCNSAWVLPARKMQNRMIPHIQESTLPVALAKVRAEMPDVENITIHDFRRTARTHLAALG
CCCCEEECCHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHC
VDPVVAERCLNHRIKGVEGIYNRHQYFDERKAALAQWVGLLVALERGEDYNVTPINKTHK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
TA
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]