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The map label for this gene is xni

Identifier: 153948056

GI number: 153948056

Start: 1203774

End: 1204529

Strand: Reverse

Name: xni

Synonym: YpsIP31758_1002

Alternate gene names: 153948056

Gene position: 1204529-1203774 (Counterclockwise)

Preceding gene: 153947482

Following gene: 153950116

Centisome position: 25.5

GC content: 47.88

Gene sequence:

>756_bases
ATGCAAATACACCTTCTTATTGTCGATGCTCTTAATTTGATTCGCCGTATTCATGCGGTGCAGGGGTCACCTTGTGTTAA
GGCCTGCCAGCATGCACTGCAACAACTGATTCAACACAGCCAACCCAGCCATGCCGTTGCCGTTTTTGATGAAGATGACC
GCTCTGATAGCTGGCGACATCAATGTCTGCCAGATTACAAAGCTGGCCGCTCTCCCATGCCTGATAACCTGCAACAGGAA
ATGCCACTCATTCGCCAGGCATTTAATGAATTAGGGGTAGCATGCTGGCATTCACCCGGTAATGAAGCCGATGACTTAGC
CGCCACTCTGGTGGTAAAAGTTGCTGGAGCGGGCCATCAGGTAACCATCGTTTCTACCGACAAAGGCTATTGCCAGTTAT
TGGCTCCCAATGTCCAAATTCGTGACTATTTCCAAAAGCGGTGGCTGGATATGCCGTTTGTGAAGCAGGAGTTTGGTGTA
TTGCCTCGTCAATTACCTGATTACTGGGGGCTGGCGGGGATCAGCAGCAGTAAAATTCCAGGTGTTGCAGGCGTTGGTGC
CAAAACCGCTACGCTGCTACTGCAACAAGCCGATACGTTGGAAGTGCTCTATCAGAATCTGGAATCAATACCGGAGAAAT
GGCGTAAAAAATTACAACAACACCAACAGATGGCGTTTACCTGCAAACAAATCGCCACGCTGAAAACGGACTTATTATTG
AGTGGCAATCTACAACAGTTACGTTTGAAAAAATAA

Upstream 100 bases:

>100_bases
GCTGCTGCAACGCCAAGTAAGAAGGGAATTCACTGGGCGACTAACGTTGCCCAATATTACTCGGGCTTTATGACGATTCA
GCCCTTACATAAAACAGGTT

Downstream 100 bases:

>100_bases
TATACGCATAAAAACTAAGGGGCCAATAGGCCCCTCAGACTGCTGACAAACCCCGATGACGCGATCTTGAACGGTGAGGA
TAGGCAGAGGAGTAAAGCGT

Product: exonuclease IX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MQIHLLIVDALNLIRRIHAVQGSPCVKACQHALQQLIQHSQPSHAVAVFDEDDRSDSWRHQCLPDYKAGRSPMPDNLQQE
MPLIRQAFNELGVACWHSPGNEADDLAATLVVKVAGAGHQVTIVSTDKGYCQLLAPNVQIRDYFQKRWLDMPFVKQEFGV
LPRQLPDYWGLAGISSSKIPGVAGVGAKTATLLLQQADTLEVLYQNLESIPEKWRKKLQQHQQMAFTCKQIATLKTDLLL
SGNLQQLRLKK

Sequences:

>Translated_251_residues
MQIHLLIVDALNLIRRIHAVQGSPCVKACQHALQQLIQHSQPSHAVAVFDEDDRSDSWRHQCLPDYKAGRSPMPDNLQQE
MPLIRQAFNELGVACWHSPGNEADDLAATLVVKVAGAGHQVTIVSTDKGYCQLLAPNVQIRDYFQKRWLDMPFVKQEFGV
LPRQLPDYWGLAGISSSKIPGVAGVGAKTATLLLQQADTLEVLYQNLESIPEKWRKKLQQHQQMAFTCKQIATLKTDLLL
SGNLQQLRLKK
>Mature_251_residues
MQIHLLIVDALNLIRRIHAVQGSPCVKACQHALQQLIQHSQPSHAVAVFDEDDRSDSWRHQCLPDYKAGRSPMPDNLQQE
MPLIRQAFNELGVACWHSPGNEADDLAATLVVKVAGAGHQVTIVSTDKGYCQLLAPNVQIRDYFQKRWLDMPFVKQEFGV
LPRQLPDYWGLAGISSSKIPGVAGVGAKTATLLLQQADTLEVLYQNLESIPEKWRKKLQQHQQMAFTCKQIATLKTDLLL
SGNLQQLRLKK

Specific function: May have a role in processing of nucleic acids. It is probably not an exonuclease; metal-binding residues found in paralogs are missing

COG id: COG0258

COG function: function code L; 5'-3' exonuclease (including N-terminal domain of PolI)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 5'-3' exonuclease domain

Homologues:

Organism=Escherichia coli, GI226510970, Length=251, Percent_Identity=70.9163346613546, Blast_Score=387, Evalue=1e-109,
Organism=Escherichia coli, GI1790294, Length=263, Percent_Identity=32.6996197718631, Blast_Score=129, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XNI_YERP3 (A7FFF8)

Other databases:

- EMBL:   CP000720
- RefSeq:   YP_001399986.1
- ProteinModelPortal:   A7FFF8
- SMR:   A7FFF8
- STRING:   A7FFF8
- GeneID:   5385142
- GenomeReviews:   CP000720_GR
- KEGG:   ypi:YpsIP31758_1002
- eggNOG:   COG0258
- HOGENOM:   HBG701384
- OMA:   NESEDLP
- ProtClustDB:   PRK09482
- BioCyc:   YPSE349747:YPSIP31758_1002-MONOMER
- HAMAP:   MF_01192
- InterPro:   IPR020046
- InterPro:   IPR020045
- InterPro:   IPR002421
- InterPro:   IPR020047
- InterPro:   IPR008918
- InterPro:   IPR022895
- SMART:   SM00475
- SMART:   SM00279

Pfam domain/function: PF01367 5_3_exonuc; PF02739 5_3_exonuc_N; SSF47807 5_3_exo_C

EC number: 3.1.11.- [C]

Molecular weight: Translated: 28147; Mature: 28147

Theoretical pI: Translated: 8.38; Mature: 8.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIHLLIVDALNLIRRIHAVQGSPCVKACQHALQQLIQHSQPSHAVAVFDEDDRSDSWRH
CEEEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHH
QCLPDYKAGRSPMPDNLQQEMPLIRQAFNELGVACWHSPGNEADDLAATLVVKVAGAGHQ
HCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHCEEEECCCCCCHHHHHHHHHHHCCCCCCE
VTIVSTDKGYCQLLAPNVQIRDYFQKRWLDMPFVKQEFGVLPRQLPDYWGLAGISSSKIP
EEEEECCCCEEEEECCCCHHHHHHHHHCCCCCHHHHHHCCCCHHCCHHHCCCCCCCCCCC
GVAGVGAKTATLLLQQADTLEVLYQNLESIPEKWRKKLQQHQQMAFTCKQIATLKTDLLL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SGNLQQLRLKK
CCCHHHHCCCC
>Mature Secondary Structure
MQIHLLIVDALNLIRRIHAVQGSPCVKACQHALQQLIQHSQPSHAVAVFDEDDRSDSWRH
CEEEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHH
QCLPDYKAGRSPMPDNLQQEMPLIRQAFNELGVACWHSPGNEADDLAATLVVKVAGAGHQ
HCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHCEEEECCCCCCHHHHHHHHHHHCCCCCCE
VTIVSTDKGYCQLLAPNVQIRDYFQKRWLDMPFVKQEFGVLPRQLPDYWGLAGISSSKIP
EEEEECCCCEEEEECCCCHHHHHHHHHCCCCCHHHHHHCCCCHHCCHHHCCCCCCCCCCC
GVAGVGAKTATLLLQQADTLEVLYQNLESIPEKWRKKLQQHQQMAFTCKQIATLKTDLLL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SGNLQQLRLKK
CCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA