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The map label for this gene is int [H]

Identifier: 153948003

GI number: 153948003

Start: 3317905

End: 3318843

Strand: Direct

Name: int [H]

Synonym: YpsIP31758_2946

Alternate gene names: 153948003

Gene position: 3317905-3318843 (Clockwise)

Preceding gene: 153947377

Following gene: 153947392

Centisome position: 70.25

GC content: 43.98

Gene sequence:

>939_bases
ATGTTGTCCGCGCTTGGCTGCTCACTGCTGCGAACCGGTACAGGCATCGTTGCTTTGTATAACCGAATTAATAGTGTCGC
AGTTGTCACTGTATCAGATTGGGTTAAAACTTATACAGAAGTGCTAAGTAAGCGCGGATTAAAAAGCAAGACGATCACTG
GCTACAATAGTCGCTTGGATGTAGTCGATGAGGTTTTCGCATCAAGGACTATTGACAGTATTAGCACTAAAGACATTGCA
ACACTTCTTAACGATTACACAAATAATGGAAAGGCGGCATCTGCTAAGTTGATGCGATCATTTTTGACTGATTTTTTCAG
AGAGGCAGTATCCGAGGGGATTATTTACAATAACCCCGTCGATGCAACAAAAAACCCAAAGATAGAGGTTAAGCGCGCAA
GGCTGTCGCTTGATAACTTCCTATCCATTAGGGCGGCAGCGGCTGACATGCCGGGCTGGGTTGTTGATAGCATGGATCTG
GCTATAGTGACAGGGCAACGTGTGGGGGATGTTCGTAAAATGAAGTGGTCTGATATTAAAGATGATAAACTTTTCGTTGA
GCAGGAAAAGACAGGAATGAGGATCATAATCCCCTTTGATGTTAAGCTAGATACCCTCTTGCTCTCTTTGCGTGATATCA
TCGCGCGCTGCGAAAATCGCGCAATCAAAGGCGAAACGATAATTTCGTCCGACAAAGGTGAATCATTTGCAGATAAGACA
CTGACAAAGCGATTCGCCAAAGCGAGAGATTTAGCAAACATAACATGGGAAGGAATTAACCCACCGCCATTTCATGAGAT
ACGGAGTTTAGCTTCACGACTCTATGAAAAGGAAATGGGTAAAGAATTTTCTCAAAAAATCCTCGGGCATAAATCCGCAC
AAACGACCGATAAGTATCGCGACGTTCGCGGAAGTGAATGGATCGAGATAGAAGTGTAG

Upstream 100 bases:

>100_bases
TTTCATAGTTATTTTATCTGTCCTCTACTTAATAACGTGATAGCAATCTTCACGAACGTTACGGAAGCCTGCTGCAAACT
TAGCTACTTCAGGCAAGCAG

Downstream 100 bases:

>100_bases
TGAACGAATTTCGAATAATTTCGACCTGCACAGTGTAACCAACTGATTAAATTAGAAAAAATTAAGGGGAACCTTTGCAA
GGTAAAGCGCTCCAAGAATT

Product: integrase

Products: NA

Alternate protein names: Int(Lambda); Prophage e14 integrase [H]

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MLSALGCSLLRTGTGIVALYNRINSVAVVTVSDWVKTYTEVLSKRGLKSKTITGYNSRLDVVDEVFASRTIDSISTKDIA
TLLNDYTNNGKAASAKLMRSFLTDFFREAVSEGIIYNNPVDATKNPKIEVKRARLSLDNFLSIRAAAADMPGWVVDSMDL
AIVTGQRVGDVRKMKWSDIKDDKLFVEQEKTGMRIIIPFDVKLDTLLLSLRDIIARCENRAIKGETIISSDKGESFADKT
LTKRFAKARDLANITWEGINPPPFHEIRSLASRLYEKEMGKEFSQKILGHKSAQTTDKYRDVRGSEWIEIEV

Sequences:

>Translated_312_residues
MLSALGCSLLRTGTGIVALYNRINSVAVVTVSDWVKTYTEVLSKRGLKSKTITGYNSRLDVVDEVFASRTIDSISTKDIA
TLLNDYTNNGKAASAKLMRSFLTDFFREAVSEGIIYNNPVDATKNPKIEVKRARLSLDNFLSIRAAAADMPGWVVDSMDL
AIVTGQRVGDVRKMKWSDIKDDKLFVEQEKTGMRIIIPFDVKLDTLLLSLRDIIARCENRAIKGETIISSDKGESFADKT
LTKRFAKARDLANITWEGINPPPFHEIRSLASRLYEKEMGKEFSQKILGHKSAQTTDKYRDVRGSEWIEIEV
>Mature_312_residues
MLSALGCSLLRTGTGIVALYNRINSVAVVTVSDWVKTYTEVLSKRGLKSKTITGYNSRLDVVDEVFASRTIDSISTKDIA
TLLNDYTNNGKAASAKLMRSFLTDFFREAVSEGIIYNNPVDATKNPKIEVKRARLSLDNFLSIRAAAADMPGWVVDSMDL
AIVTGQRVGDVRKMKWSDIKDDKLFVEQEKTGMRIIIPFDVKLDTLLLSLRDIIARCENRAIKGETIISSDKGESFADKT
LTKRFAKARDLANITWEGINPPPFHEIRSLASRLYEKEMGKEFSQKILGHKSAQTTDKYRDVRGSEWIEIEV

Specific function: Integrase from the cryptic lambdoic prophage e14. Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the h

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI1787386, Length=312, Percent_Identity=38.7820512820513, Blast_Score=196, Evalue=2e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016177
- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR015094
- InterPro:   IPR023109
- InterPro:   IPR013087 [H]

Pfam domain/function: PF09003 Phage_integ_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 34983; Mature: 34983

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSALGCSLLRTGTGIVALYNRINSVAVVTVSDWVKTYTEVLSKRGLKSKTITGYNSRLD
CCCHHHHHHHHCCCHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHCCCCCCEECCCCCHHH
VVDEVFASRTIDSISTKDIATLLNDYTNNGKAASAKLMRSFLTDFFREAVSEGIIYNNPV
HHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCEECCCC
DATKNPKIEVKRARLSLDNFLSIRAAAADMPGWVVDSMDLAIVTGQRVGDVRKMKWSDIK
CCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCEECCCCEEEEECCHHCHHHHCCCCCCC
DDKLFVEQEKTGMRIIIPFDVKLDTLLLSLRDIIARCENRAIKGETIISSDKGESFADKT
CCCEEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHH
LTKRFAKARDLANITWEGINPPPFHEIRSLASRLYEKEMGKEFSQKILGHKSAQTTDKYR
HHHHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
DVRGSEWIEIEV
HCCCCCEEEEEC
>Mature Secondary Structure
MLSALGCSLLRTGTGIVALYNRINSVAVVTVSDWVKTYTEVLSKRGLKSKTITGYNSRLD
CCCHHHHHHHHCCCHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHCCCCCCEECCCCCHHH
VVDEVFASRTIDSISTKDIATLLNDYTNNGKAASAKLMRSFLTDFFREAVSEGIIYNNPV
HHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCEECCCC
DATKNPKIEVKRARLSLDNFLSIRAAAADMPGWVVDSMDLAIVTGQRVGDVRKMKWSDIK
CCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCEECCCCEEEEECCHHCHHHHCCCCCCC
DDKLFVEQEKTGMRIIIPFDVKLDTLLLSLRDIIARCENRAIKGETIISSDKGESFADKT
CCCEEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHH
LTKRFAKARDLANITWEGINPPPFHEIRSLASRLYEKEMGKEFSQKILGHKSAQTTDKYR
HHHHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
DVRGSEWIEIEV
HCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]