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The map label for this gene is iucA [H]

Identifier: 153948002

GI number: 153948002

Start: 874770

End: 876542

Strand: Reverse

Name: iucA [H]

Synonym: YpsIP31758_0714

Alternate gene names: 153948002

Gene position: 876542-874770 (Counterclockwise)

Preceding gene: 153947998

Following gene: 153949111

Centisome position: 18.56

GC content: 53.19

Gene sequence:

>1773_bases
ATGACTATCCCAGTAGAAACCTTAGCAACCGATGTGGCTGCTCAATGTTTCCTCAACGCGCTGATTCGTGAAACCCAGGA
CTGGCAGATCGTTCCGGCAGCGGGCCACCAACCGTACCCACAACTCCACATTCCTCTTTCTTCTTCACACGCTATCCACA
TTGCCTTATGCCATATCTCCCCAACACAGCATCATCACTATCTGTTCCCTGCCTACCTGCATCAGCAGGGTAATGATAGG
CAGGATGATGACACCCCGGTAAAACTCGGGATCGAACAGTTGGTGACGCTTCTGTTGGAGAAGCCAACGGTAAAAGGTGA
GCTGTCTGATGATGTGGTTGCTCGTTTCCGTCAACGGGTGCTAGAAAGTCATGATAATACTCAGCAAGCGATTAATATTC
GTCTGGATTGGCCGTCATTACGCGATAAACCACTTAATTTTGCCCAGGCAGAACAAGGATTACTGGCCGGCCATGCCTTT
CACCCGGCACCGAAATCCCATCAACCTTTTAATGAAAAACAGGCCCAGCGTTATCTGCCCGATTTTGCCTCCCGCTTCCC
ACTACGCTGGTTTGCAGTCGATAAACGCTACCTGTGCGGCGATAGCCTAAAGCTAACGCTACAACACCGGCTGCAACGCT
TTGCCAGCGAAAGCGCCCCACAATTACTCGCGTATTTTACCGATGACGTTTGGCTGCTCCCCATGCACCCCTGGCAAGCC
GATCACCTATTGAAACAAGACTGGTGCCAGCAATTAGTACAACAAAACGCGTTGCATGATCTGGGCGAAGCGGGTGAACG
CTGGCTACCCACCAGCTCTTCACGTTCACTGTACAGCCCGTCAAACCGCGACATGGTCAAGTTCTCACTCAGTGTGCGCC
TGACCAACTCAGTACGAACCCTGTCGGTAAAAGAGGCCAAACGCGGTATGCGCTTGGCACGTTTGGCTCAAACACCCCGC
TGGCAAGAGCTGCAAGCGCGCTACCCGACTTTCCGTGTGATGCAGGAAGATGGTTGGGCCGGTTTGCGTTCAGCCGATTT
CACTCTTCAAGAAGAGAGTCTGTTGGTGCTACGTGACAACCTGCTATTCAGCCAACCCGATAGCCAGACCAATGTGTTGG
TCACCTTGACACAAGCCGCGCCCGATGGGGGGGACAGCCTGCTGGCCAGTGCTGTGCGTCGTTTGGCTGCCCGTCTGAAT
CTGCCATTGCAACAGGCCGCTTTCTGCTGGCTGGATGCTTACTGCCAGCACGTCTTATTGCCACTGTTCAGCACCGAGGC
TGACTACGGGCTGGTGTTGTTAGCGCATCAGCAAAATATTCTGGTGGAGATGCAGCAAGATCTGCCTGTCGGTATGTTGT
ACCGCGACTGCCAAGGGAGCGGCTTTACCCAGAGCGCGCTGCCGTGGTTGGCGGAAATTGGCGAAGCCGAAGCGGAAAAT
AGCTTTAGCGAACAGCAATTATTACGTTACTTCCCGTATTACCTGCTGGTGAACTCCAGCCTCGCGGTAACGGCTGCCTT
GGCTGCCGCAGGTTTCGACAGCGAGGAAAATTTGATGGTTCGTGTGCGTGACGCACTCAGCGCCCTGCGTACTTGCGCCA
AAAACACCTTATGTCTGGATTACGTACTTGATAGCCCACATTGGCACTGCAAAGGTAATTTCTTCTGCTATCTACACGAT
CACAACGAAAACACCATCGTTGATCCGGCAGTGATCTACTTCGATTTCGTTAACCCTCTGCACCAGGGGGTGATCCATGG
GGCCACACGCTAA

Upstream 100 bases:

>100_bases
AAGGAGATTTATTGAAAAATCGTATCATATTCCAATTGATAATGATAACCACTATTGATATAAGAATCGTTCTCAATGGA
TTAATAAGCGACATGACATC

Downstream 100 bases:

>100_bases
GTTAATACACTCCGGTGGCAGTTTTTACTGTGAACATCTGGGAAAGGCGCTGACTCTCGGTCTGGGACTTGATGGCAGTG
CCGTACTGCACTTGCCTGGG

Product: aerobactin siderophore biosynthesis protein IucA

Products: ADP; phosphate; aerobactin

Alternate protein names: NA

Number of amino acids: Translated: 590; Mature: 589

Protein sequence:

>590_residues
MTIPVETLATDVAAQCFLNALIRETQDWQIVPAAGHQPYPQLHIPLSSSHAIHIALCHISPTQHHHYLFPAYLHQQGNDR
QDDDTPVKLGIEQLVTLLLEKPTVKGELSDDVVARFRQRVLESHDNTQQAINIRLDWPSLRDKPLNFAQAEQGLLAGHAF
HPAPKSHQPFNEKQAQRYLPDFASRFPLRWFAVDKRYLCGDSLKLTLQHRLQRFASESAPQLLAYFTDDVWLLPMHPWQA
DHLLKQDWCQQLVQQNALHDLGEAGERWLPTSSSRSLYSPSNRDMVKFSLSVRLTNSVRTLSVKEAKRGMRLARLAQTPR
WQELQARYPTFRVMQEDGWAGLRSADFTLQEESLLVLRDNLLFSQPDSQTNVLVTLTQAAPDGGDSLLASAVRRLAARLN
LPLQQAAFCWLDAYCQHVLLPLFSTEADYGLVLLAHQQNILVEMQQDLPVGMLYRDCQGSGFTQSALPWLAEIGEAEAEN
SFSEQQLLRYFPYYLLVNSSLAVTAALAAAGFDSEENLMVRVRDALSALRTCAKNTLCLDYVLDSPHWHCKGNFFCYLHD
HNENTIVDPAVIYFDFVNPLHQGVIHGATR

Sequences:

>Translated_590_residues
MTIPVETLATDVAAQCFLNALIRETQDWQIVPAAGHQPYPQLHIPLSSSHAIHIALCHISPTQHHHYLFPAYLHQQGNDR
QDDDTPVKLGIEQLVTLLLEKPTVKGELSDDVVARFRQRVLESHDNTQQAINIRLDWPSLRDKPLNFAQAEQGLLAGHAF
HPAPKSHQPFNEKQAQRYLPDFASRFPLRWFAVDKRYLCGDSLKLTLQHRLQRFASESAPQLLAYFTDDVWLLPMHPWQA
DHLLKQDWCQQLVQQNALHDLGEAGERWLPTSSSRSLYSPSNRDMVKFSLSVRLTNSVRTLSVKEAKRGMRLARLAQTPR
WQELQARYPTFRVMQEDGWAGLRSADFTLQEESLLVLRDNLLFSQPDSQTNVLVTLTQAAPDGGDSLLASAVRRLAARLN
LPLQQAAFCWLDAYCQHVLLPLFSTEADYGLVLLAHQQNILVEMQQDLPVGMLYRDCQGSGFTQSALPWLAEIGEAEAEN
SFSEQQLLRYFPYYLLVNSSLAVTAALAAAGFDSEENLMVRVRDALSALRTCAKNTLCLDYVLDSPHWHCKGNFFCYLHD
HNENTIVDPAVIYFDFVNPLHQGVIHGATR
>Mature_589_residues
TIPVETLATDVAAQCFLNALIRETQDWQIVPAAGHQPYPQLHIPLSSSHAIHIALCHISPTQHHHYLFPAYLHQQGNDRQ
DDDTPVKLGIEQLVTLLLEKPTVKGELSDDVVARFRQRVLESHDNTQQAINIRLDWPSLRDKPLNFAQAEQGLLAGHAFH
PAPKSHQPFNEKQAQRYLPDFASRFPLRWFAVDKRYLCGDSLKLTLQHRLQRFASESAPQLLAYFTDDVWLLPMHPWQAD
HLLKQDWCQQLVQQNALHDLGEAGERWLPTSSSRSLYSPSNRDMVKFSLSVRLTNSVRTLSVKEAKRGMRLARLAQTPRW
QELQARYPTFRVMQEDGWAGLRSADFTLQEESLLVLRDNLLFSQPDSQTNVLVTLTQAAPDGGDSLLASAVRRLAARLNL
PLQQAAFCWLDAYCQHVLLPLFSTEADYGLVLLAHQQNILVEMQQDLPVGMLYRDCQGSGFTQSALPWLAEIGEAEAENS
FSEQQLLRYFPYYLLVNSSLAVTAALAAAGFDSEENLMVRVRDALSALRTCAKNTLCLDYVLDSPHWHCKGNFFCYLHDH
NENTIVDPAVIYFDFVNPLHQGVIHGATR

Specific function: Unknown

COG id: COG4264

COG function: function code Q; Siderophore synthetase component

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iucA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007310
- InterPro:   IPR022770 [H]

Pfam domain/function: PF06276 FhuF; PF04183 IucA_IucC [H]

EC number: 6.3.2.27

Molecular weight: Translated: 66908; Mature: 66776

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIPVETLATDVAAQCFLNALIRETQDWQIVPAAGHQPYPQLHIPLSSSHAIHIALCHIS
CCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEEECCCCCEEEEEEEEEC
PTQHHHYLFPAYLHQQGNDRQDDDTPVKLGIEQLVTLLLEKPTVKGELSDDVVARFRQRV
CCCCCCEECHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
LESHDNTQQAINIRLDWPSLRDKPLNFAQAEQGLLAGHAFHPAPKSHQPFNEKQAQRYLP
HHCCCCCCEEEEEEEECCCCCCCCCCHHHHHCCHHCCCCCCCCCCCCCCCCHHHHHHHHH
DFASRFPLRWFAVDKRYLCGDSLKLTLQHRLQRFASESAPQLLAYFTDDVWLLPMHPWQA
HHHHHCCEEEEEECCCEECCCCHHHHHHHHHHHHHCCCCCHHHHEECCCEEEEECCCCCH
DHLLKQDWCQQLVQQNALHDLGEAGERWLPTSSSRSLYSPSNRDMVKFSLSVRLTNSVRT
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCEEE
LSVKEAKRGMRLARLAQTPRWQELQARYPTFRVMQEDGWAGLRSADFTLQEESLLVLRDN
EEHHHHHHHHHHHHHHCCCCHHHHHHCCCEEEEEECCCCCCCCCCCCEECCCCEEEEECC
LLFSQPDSQTNVLVTLTQAAPDGGDSLLASAVRRLAARLNLPLQQAAFCWLDAYCQHVLL
EEECCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
PLFSTEADYGLVLLAHQQNILVEMQQDLPVGMLYRDCQGSGFTQSALPWLAEIGEAEAEN
HHHCCCCCCCEEEEEECCCEEEEECCCCCHHHHHHCCCCCCCCHHHHHHHHHHCCHHHCC
SFSEQQLLRYFPYYLLVNSSLAVTAALAAAGFDSEENLMVRVRDALSALRTCAKNTLCLD
CCCHHHHHHHCCHHEEECCCHHHHHHHHHHCCCCCCCHHEEHHHHHHHHHHHHCCCEEEE
YVLDSPHWHCKGNFFCYLHDHNENTIVDPAVIYFDFVNPLHQGVIHGATR
EEECCCCEEECCCEEEEEEECCCCCEECHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TIPVETLATDVAAQCFLNALIRETQDWQIVPAAGHQPYPQLHIPLSSSHAIHIALCHIS
CCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEEECCCCCEEEEEEEEEC
PTQHHHYLFPAYLHQQGNDRQDDDTPVKLGIEQLVTLLLEKPTVKGELSDDVVARFRQRV
CCCCCCEECHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
LESHDNTQQAINIRLDWPSLRDKPLNFAQAEQGLLAGHAFHPAPKSHQPFNEKQAQRYLP
HHCCCCCCEEEEEEEECCCCCCCCCCHHHHHCCHHCCCCCCCCCCCCCCCCHHHHHHHHH
DFASRFPLRWFAVDKRYLCGDSLKLTLQHRLQRFASESAPQLLAYFTDDVWLLPMHPWQA
HHHHHCCEEEEEECCCEECCCCHHHHHHHHHHHHHCCCCCHHHHEECCCEEEEECCCCCH
DHLLKQDWCQQLVQQNALHDLGEAGERWLPTSSSRSLYSPSNRDMVKFSLSVRLTNSVRT
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCEEE
LSVKEAKRGMRLARLAQTPRWQELQARYPTFRVMQEDGWAGLRSADFTLQEESLLVLRDN
EEHHHHHHHHHHHHHHCCCCHHHHHHCCCEEEEEECCCCCCCCCCCCEECCCCEEEEECC
LLFSQPDSQTNVLVTLTQAAPDGGDSLLASAVRRLAARLNLPLQQAAFCWLDAYCQHVLL
EEECCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
PLFSTEADYGLVLLAHQQNILVEMQQDLPVGMLYRDCQGSGFTQSALPWLAEIGEAEAEN
HHHCCCCCCCEEEEEECCCEEEEECCCCCHHHHHHCCCCCCCCHHHHHHHHHHCCHHHCC
SFSEQQLLRYFPYYLLVNSSLAVTAALAAAGFDSEENLMVRVRDALSALRTCAKNTLCLD
CCCHHHHHHHCCHHEEECCCHHHHHHHHHHCCCCCCCHHEEHHHHHHHHHHHHCCCEEEE
YVLDSPHWHCKGNFFCYLHDHNENTIVDPAVIYFDFVNPLHQGVIHGATR
EEECCCCEEECCCEEEEEEECCCCCEECHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; citrate; N6-acetyl-N6-hydroxylysine

Specific reaction: 4 ATP + citrate + N6-acetyl-N6-hydroxylysine = 4 ADP + 4 phosphate + aerobactin

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8003107 [H]