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The map label for this gene is aaeA [H]

Identifier: 153947637

GI number: 153947637

Start: 496906

End: 497841

Strand: Direct

Name: aaeA [H]

Synonym: YpsIP31758_0420

Alternate gene names: 153947637

Gene position: 496906-497841 (Clockwise)

Preceding gene: 153949632

Following gene: 153947237

Centisome position: 10.52

GC content: 51.71

Gene sequence:

>936_bases
GTGAGTACATTTTCATTAAAAATAATCCGCGTTGGCATCACCGTCTTGGTGGTCGTACTGGCTGTTATCGCGATTTTCAA
CGTGTGGGCCTTCTATACTGAATCGCCGTGGACCCGTGATGCTAAATTTACCGCAGACGTGGTCGCTATCGCACCGGATG
TCAGCGGCTTACTGACCGAAGTACCGGTAAAAGACAACCAACTGGTGCAGAAAGGCCAGATTCTGTTTGTCATTGATCAG
CCCCGTTATCAGCAAGCGTTGGCCGAAGCCGAGGCCGATGTGGCTTATTACCAGACCTTGGCTGCGGAGAAGCAACGGGA
GTTCAGCAGGCGGCACCTCCTGGGTATTCAGGCACTGTCACAAGAAGAGATTGACCAGGCAAGCAATGTGTTACAAACCG
TCCAGCATCAGCTGGCAAAAACCATTGCCGTGAGGAATTTAGCCCGCCTTGATCTGGAAAGAACCACGATACGTGCACCA
GCAGAAGGGTGGGTGACCAACCTGAATGTACATGCTGGTGAGTTTATTAACCGTGGGGCCACGGCAGTCGCATTGGTGAA
AAAAGATACTTTTTACATTTTAGCCTATCTGGAGGAGACGAAGCTCGAAGGGGTTAAACCGGGCTACCGAGCGGAAATTA
CCCCACTGGGCAGTAACCGCATTCTGCATGGTACGGTCGATAGCATTTCAGCCGGTGTTACCAATAGCAGTAGCAGTGCC
GACAGCAAAGGGCTGGCGACCATTGATAATAATCTTGAATGGGTACGCTTGGCGCAACGGGTACCGGTGAAGATTCATCT
GGATAGCGAAGACCAGCAATATTTGTATCCGGCGGGCACCACGGCTACGGTGGTGATCACCGGGCCGAATGATCGTGATC
CTCATCAGGCATCGCCCATGACCAAGTTGATGCATCGTCTACGTGAGTTTGGCTAA

Upstream 100 bases:

>100_bases
ACCGGTATTTACGAGTTTGTTTGGCACCCGGCTCTTTTTAATACGGCGCTGTATTGTTGCCTGTTTTATTTAACATCCCG
TCTTTTTTCCTGAGGTCACC

Downstream 100 bases:

>100_bases
TATGACCCACCCAAGCTTTATTCGCCTGCGGTTTGCGTTCAAGCTGAGTTTTGCCATTGTGGCGGCATTATTTCTTGGCT
TTCATCTGCAATTGGAAACA

Product: p-hydroxybenzoic acid efflux subunit AaeA

Products: NA

Alternate protein names: pHBA efflux pump protein A [H]

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MSTFSLKIIRVGITVLVVVLAVIAIFNVWAFYTESPWTRDAKFTADVVAIAPDVSGLLTEVPVKDNQLVQKGQILFVIDQ
PRYQQALAEAEADVAYYQTLAAEKQREFSRRHLLGIQALSQEEIDQASNVLQTVQHQLAKTIAVRNLARLDLERTTIRAP
AEGWVTNLNVHAGEFINRGATAVALVKKDTFYILAYLEETKLEGVKPGYRAEITPLGSNRILHGTVDSISAGVTNSSSSA
DSKGLATIDNNLEWVRLAQRVPVKIHLDSEDQQYLYPAGTTATVVITGPNDRDPHQASPMTKLMHRLREFG

Sequences:

>Translated_311_residues
MSTFSLKIIRVGITVLVVVLAVIAIFNVWAFYTESPWTRDAKFTADVVAIAPDVSGLLTEVPVKDNQLVQKGQILFVIDQ
PRYQQALAEAEADVAYYQTLAAEKQREFSRRHLLGIQALSQEEIDQASNVLQTVQHQLAKTIAVRNLARLDLERTTIRAP
AEGWVTNLNVHAGEFINRGATAVALVKKDTFYILAYLEETKLEGVKPGYRAEITPLGSNRILHGTVDSISAGVTNSSSSA
DSKGLATIDNNLEWVRLAQRVPVKIHLDSEDQQYLYPAGTTATVVITGPNDRDPHQASPMTKLMHRLREFG
>Mature_310_residues
STFSLKIIRVGITVLVVVLAVIAIFNVWAFYTESPWTRDAKFTADVVAIAPDVSGLLTEVPVKDNQLVQKGQILFVIDQP
RYQQALAEAEADVAYYQTLAAEKQREFSRRHLLGIQALSQEEIDQASNVLQTVQHQLAKTIAVRNLARLDLERTTIRAPA
EGWVTNLNVHAGEFINRGATAVALVKKDTFYILAYLEETKLEGVKPGYRAEITPLGSNRILHGTVDSISAGVTNSSSSAD
SKGLATIDNNLEWVRLAQRVPVKIHLDSEDQQYLYPAGTTATVVITGPNDRDPHQASPMTKLMHRLREFG

Specific function: Unknown

COG id: COG1566

COG function: function code V; Multidrug resistance efflux pump

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1789637, Length=311, Percent_Identity=72.0257234726688, Blast_Score=472, Evalue=1e-134,
Organism=Escherichia coli, GI87081951, Length=283, Percent_Identity=38.5159010600707, Blast_Score=201, Evalue=6e-53,
Organism=Escherichia coli, GI1790519, Length=311, Percent_Identity=29.2604501607717, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1790024, Length=328, Percent_Identity=28.0487804878049, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1788711, Length=345, Percent_Identity=24.6376811594203, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1789041, Length=307, Percent_Identity=24.4299674267101, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022871
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 34376; Mature: 34244

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTFSLKIIRVGITVLVVVLAVIAIFNVWAFYTESPWTRDAKFTADVVAIAPDVSGLLTE
CCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCHHHHEE
VPVKDNQLVQKGQILFVIDQPRYQQALAEAEADVAYYQTLAAEKQREFSRRHLLGIQALS
CCCCCCHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
QEEIDQASNVLQTVQHQLAKTIAVRNLARLDLERTTIRAPAEGWVTNLNVHAGEFINRGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHEECCCCCCCEEEEEEEHHHHHHCCC
TAVALVKKDTFYILAYLEETKLEGVKPGYRAEITPLGSNRILHGTVDSISAGVTNSSSSA
EEEEEEECCCEEEEEEEEHHHCCCCCCCCCEEEEECCCCCEEEECHHHHHCCCCCCCCCC
DSKGLATIDNNLEWVRLAQRVPVKIHLDSEDQQYLYPAGTTATVVITGPNDRDPHQASPM
CCCCCEEECCCHHHHHHHHHCCEEEEECCCCCEEEEECCCEEEEEEECCCCCCCCCCCHH
TKLMHRLREFG
HHHHHHHHHCC
>Mature Secondary Structure 
STFSLKIIRVGITVLVVVLAVIAIFNVWAFYTESPWTRDAKFTADVVAIAPDVSGLLTE
CCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCHHHHEE
VPVKDNQLVQKGQILFVIDQPRYQQALAEAEADVAYYQTLAAEKQREFSRRHLLGIQALS
CCCCCCHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
QEEIDQASNVLQTVQHQLAKTIAVRNLARLDLERTTIRAPAEGWVTNLNVHAGEFINRGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHEECCCCCCCEEEEEEEHHHHHHCCC
TAVALVKKDTFYILAYLEETKLEGVKPGYRAEITPLGSNRILHGTVDSISAGVTNSSSSA
EEEEEEECCCEEEEEEEEHHHCCCCCCCCCEEEEECCCCCEEEECHHHHHCCCCCCCCCC
DSKGLATIDNNLEWVRLAQRVPVKIHLDSEDQQYLYPAGTTATVVITGPNDRDPHQASPM
CCCCCEEECCCHHHHHHHHHCCEEEEECCCCCEEEEECCCEEEEEEECCCCCCCCCCCHH
TKLMHRLREFG
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA