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The map label for this gene is ygdL [H]

Identifier: 153947627

GI number: 153947627

Start: 1197590

End: 1198417

Strand: Direct

Name: ygdL [H]

Synonym: YpsIP31758_0996

Alternate gene names: 153947627

Gene position: 1197590-1198417 (Clockwise)

Preceding gene: 153949687

Following gene: 153947641

Centisome position: 25.35

GC content: 48.43

Gene sequence:

>828_bases
ATGAGCACAGCCTATTCCGAAGCTTACCAACAGCGGTTTGGTGGTATTGCACGCCTCTATGGCCAACAGGCATTGGCGCT
TTTTTCACAGGCGCATGTTTGTGTCATCGGTATTGGCGGCGTAGGCTCATGGGTGGCGGAAGCATTGGCGCGTACTGGTA
TCGGTGCGATTACACTAATTGATATGGATGATGTTTGTGTCACGAATACTAACCGTCAAATCCATGCTCTGCGCCACAAC
ATCGGGCAGGCTAAAACAGAAGTCATGGCCGAGCGTATTCTGGCCATCAATCCTGAATGTCATGTGACTTGTATTGATGA
TTTTATTACTGCGGATAATGTCGCTGAGCTTTTAAATAAGAATTTCAGCTATGTTATTGATGCAATTGATAGTGTGCGCC
CAAAAGCTGCGCTGTTGTCTTACTGCCGTCGCTATAAAATCCCAGTGGTGACTACCGGTGGAGCGGGTGGGCAAATTGAT
CCAACCCGTATTGCCGTGGTTGATCTGGCTAAAACCATCCAAGATCCTTTAGCTGCAAAACTGCGCGAAAGACTGAAAAG
TGATTTTAACGTGGTGAAAAACAGCAAAGGTAAGCTAGGTATTGACTGTGTTTTCTCCAGTGAGCCTTTGGTCTATCCAC
AAGCCGATGGCTCTGTGTGTGCATCCCGCAGCACTGCCGAAGGACCTAAAAAAATGGATTGCACCTCTGGATTCGGCTCG
GCAACGATGGTTACTGCCACGTTTGGCTTTGTTGCTGTGTCTCATGTATTGAAGAAGATGATGGCTAAAGCGGCCCGTCA
GCACGAGTCAGCCGCCACTGCGTCATAG

Upstream 100 bases:

>100_bases
CCAGTTGGCCGCTTTTGCATGAGTACTTAGAATCTTATTGAGTACGAAGCGTCTTTTTTGAAGCCATTTATTATTTCTAC
GTTATTAAGGTAACAAGTCT

Downstream 100 bases:

>100_bases
CCACTGCGTCATAATCGATTGTTACTCTGCAACTTATTGTTCTGAATAATTATCGTTCTGCGTATTTGGCCGCGATGGTT
TGTACACCTTGAGCCAGTGC

Product: thiF family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MSTAYSEAYQQRFGGIARLYGQQALALFSQAHVCVIGIGGVGSWVAEALARTGIGAITLIDMDDVCVTNTNRQIHALRHN
IGQAKTEVMAERILAINPECHVTCIDDFITADNVAELLNKNFSYVIDAIDSVRPKAALLSYCRRYKIPVVTTGGAGGQID
PTRIAVVDLAKTIQDPLAAKLRERLKSDFNVVKNSKGKLGIDCVFSSEPLVYPQADGSVCASRSTAEGPKKMDCTSGFGS
ATMVTATFGFVAVSHVLKKMMAKAARQHESAATAS

Sequences:

>Translated_275_residues
MSTAYSEAYQQRFGGIARLYGQQALALFSQAHVCVIGIGGVGSWVAEALARTGIGAITLIDMDDVCVTNTNRQIHALRHN
IGQAKTEVMAERILAINPECHVTCIDDFITADNVAELLNKNFSYVIDAIDSVRPKAALLSYCRRYKIPVVTTGGAGGQID
PTRIAVVDLAKTIQDPLAAKLRERLKSDFNVVKNSKGKLGIDCVFSSEPLVYPQADGSVCASRSTAEGPKKMDCTSGFGS
ATMVTATFGFVAVSHVLKKMMAKAARQHESAATAS
>Mature_274_residues
STAYSEAYQQRFGGIARLYGQQALALFSQAHVCVIGIGGVGSWVAEALARTGIGAITLIDMDDVCVTNTNRQIHALRHNI
GQAKTEVMAERILAINPECHVTCIDDFITADNVAELLNKNFSYVIDAIDSVRPKAALLSYCRRYKIPVVTTGGAGGQIDP
TRIAVVDLAKTIQDPLAAKLRERLKSDFNVVKNSKGKLGIDCVFSSEPLVYPQADGSVCASRSTAEGPKKMDCTSGFGSA
TMVTATFGFVAVSHVLKKMMAKAARQHESAATAS

Specific function: Unknown

COG id: COG1179

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesA/moeB/thiF family [H]

Homologues:

Organism=Homo sapiens, GI4885649, Length=130, Percent_Identity=29.2307692307692, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI1789177, Length=267, Percent_Identity=80.1498127340824, Blast_Score=458, Evalue=1e-130,
Organism=Escherichia coli, GI87082356, Length=143, Percent_Identity=30.0699300699301, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787048, Length=131, Percent_Identity=30.5343511450382, Blast_Score=68, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6321790, Length=208, Percent_Identity=27.4038461538462, Blast_Score=95, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6322825, Length=208, Percent_Identity=33.1730769230769, Blast_Score=88, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24660640, Length=136, Percent_Identity=30.1470588235294, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24582879, Length=132, Percent_Identity=28.030303030303, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR000594 [H]

Pfam domain/function: PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 29375; Mature: 29244

Theoretical pI: Translated: 8.39; Mature: 8.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTAYSEAYQQRFGGIARLYGQQALALFSQAHVCVIGIGGVGSWVAEALARTGIGAITLI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHCCCCEEEEE
DMDDVCVTNTNRQIHALRHNIGQAKTEVMAERILAINPECHVTCIDDFITADNVAELLNK
ECCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEHHHHHHHHHHHHHHCC
NFSYVIDAIDSVRPKAALLSYCRRYKIPVVTTGGAGGQIDPTRIAVVDLAKTIQDPLAAK
CHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHH
LRERLKSDFNVVKNSKGKLGIDCVFSSEPLVYPQADGSVCASRSTAEGPKKMDCTSGFGS
HHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCC
ATMVTATFGFVAVSHVLKKMMAKAARQHESAATAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
STAYSEAYQQRFGGIARLYGQQALALFSQAHVCVIGIGGVGSWVAEALARTGIGAITLI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHCCCCEEEEE
DMDDVCVTNTNRQIHALRHNIGQAKTEVMAERILAINPECHVTCIDDFITADNVAELLNK
ECCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEHHHHHHHHHHHHHHCC
NFSYVIDAIDSVRPKAALLSYCRRYKIPVVTTGGAGGQIDPTRIAVVDLAKTIQDPLAAK
CHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHH
LRERLKSDFNVVKNSKGKLGIDCVFSSEPLVYPQADGSVCASRSTAEGPKKMDCTSGFGS
HHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCC
ATMVTATFGFVAVSHVLKKMMAKAARQHESAATAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]