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The map label for this gene is cpxR1 [H]

Identifier: 153947537

GI number: 153947537

Start: 1538840

End: 1539523

Strand: Direct

Name: cpxR1 [H]

Synonym: YpsIP31758_1313

Alternate gene names: 153947537

Gene position: 1538840-1539523 (Clockwise)

Preceding gene: 153947324

Following gene: 153947057

Centisome position: 32.58

GC content: 47.51

Gene sequence:

>684_bases
ATGAAAATTTTGTTAGTCGATGATGATCTTGAACTGGGCACGATGTTGAAGGAATATTTGGGCGGAGAGGGGTTTACTGC
CAAACATGTATTGACCGGCAAAGCGGGCATTGATGGAGCCTTGTCCGGCGATTACACCGCGCTTATCCTCGACATTATGT
TGCCTGATATGAGTGGCATTGATGTATTACGGCAAGTGCGGAAAAAAAGCCGTTTGCCGATCATTATGTTAACGGCTAAA
GGCGACAATATTGATCGGGTGATCGGTCTTGAAATGGGCGCGGATGACTACATGCCTAAACCGTGCTATCCACGTGAATT
GGTGGCTCGATTACGCGCTGTTTTACGCCGTTTTGAAGAACAGCCAAACTTATCTGCCACTGAGAGCAGTATTATCACGC
AAGGTGGATTGACACTTAACCCATCCACCCGCAGTAGCGAATGGCAGGGTAAACCGTTTGATCTGACCGCATCGGAATTC
AATCTATTAGAGCTGCTGCTACGTTCACCTGAACGCGTGGTGACTAAAGACGAACTATCCGATAAAGGGTTAGGGCGGCC
TCGCGAAGCCTATGACCGTAGTGTTGATGTACATATCAGTAATATTCGCCAGAAACTCGCCGCCCTACCGGGTAATCATT
TAAATATCGAAACGGTACGTAGCATTGGCTATCGCATCCGATAA

Upstream 100 bases:

>100_bases
GGTTAAGTGAGATTCAAGATTATGTAAGGATTGAGTAAAACTGGCTGCATGGTATTGGAATAGGCACGAAAATAGCTGGA
ATCAGGTAGGGGAGTTAAAA

Downstream 100 bases:

>100_bases
CCGTCACTGCGGAGTGAGATAACCTATGCGCGGAAGATTATTCTGGAAAATCCTGTTGGGTTTTTGGCTGACGTTTATTT
TGATGACTCAGATGTTGTGG

Product: CpxR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MKILLVDDDLELGTMLKEYLGGEGFTAKHVLTGKAGIDGALSGDYTALILDIMLPDMSGIDVLRQVRKKSRLPIIMLTAK
GDNIDRVIGLEMGADDYMPKPCYPRELVARLRAVLRRFEEQPNLSATESSIITQGGLTLNPSTRSSEWQGKPFDLTASEF
NLLELLLRSPERVVTKDELSDKGLGRPREAYDRSVDVHISNIRQKLAALPGNHLNIETVRSIGYRIR

Sequences:

>Translated_227_residues
MKILLVDDDLELGTMLKEYLGGEGFTAKHVLTGKAGIDGALSGDYTALILDIMLPDMSGIDVLRQVRKKSRLPIIMLTAK
GDNIDRVIGLEMGADDYMPKPCYPRELVARLRAVLRRFEEQPNLSATESSIITQGGLTLNPSTRSSEWQGKPFDLTASEF
NLLELLLRSPERVVTKDELSDKGLGRPREAYDRSVDVHISNIRQKLAALPGNHLNIETVRSIGYRIR
>Mature_227_residues
MKILLVDDDLELGTMLKEYLGGEGFTAKHVLTGKAGIDGALSGDYTALILDIMLPDMSGIDVLRQVRKKSRLPIIMLTAK
GDNIDRVIGLEMGADDYMPKPCYPRELVARLRAVLRRFEEQPNLSATESSIITQGGLTLNPSTRSSEWQGKPFDLTASEF
NLLELLLRSPERVVTKDELSDKGLGRPREAYDRSVDVHISNIRQKLAALPGNHLNIETVRSIGYRIR

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=226, Percent_Identity=41.1504424778761, Blast_Score=170, Evalue=8e-44,
Organism=Escherichia coli, GI2367329, Length=225, Percent_Identity=42.6666666666667, Blast_Score=167, Evalue=5e-43,
Organism=Escherichia coli, GI1788394, Length=224, Percent_Identity=35.7142857142857, Blast_Score=149, Evalue=1e-37,
Organism=Escherichia coli, GI1790860, Length=226, Percent_Identity=38.0530973451327, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI1789402, Length=225, Percent_Identity=37.7777777777778, Blast_Score=136, Evalue=9e-34,
Organism=Escherichia coli, GI1786599, Length=230, Percent_Identity=37.3913043478261, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI1786784, Length=225, Percent_Identity=35.1111111111111, Blast_Score=117, Evalue=5e-28,
Organism=Escherichia coli, GI1787229, Length=213, Percent_Identity=35.6807511737089, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1790552, Length=225, Percent_Identity=36, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=32.4561403508772, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI87082012, Length=224, Percent_Identity=33.4821428571429, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI1786911, Length=225, Percent_Identity=29.7777777777778, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI145693140, Length=229, Percent_Identity=30.1310043668122, Blast_Score=91, Evalue=4e-20,
Organism=Escherichia coli, GI1787375, Length=226, Percent_Identity=30.5309734513274, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1790299, Length=120, Percent_Identity=31.6666666666667, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25261; Mature: 25261

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILLVDDDLELGTMLKEYLGGEGFTAKHVLTGKAGIDGALSGDYTALILDIMLPDMSGI
CEEEEECCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCCH
DVLRQVRKKSRLPIIMLTAKGDNIDRVIGLEMGADDYMPKPCYPRELVARLRAVLRRFEE
HHHHHHHHHCCCCEEEEEECCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHH
QPNLSATESSIITQGGLTLNPSTRSSEWQGKPFDLTASEFNLLELLLRSPERVVTKDELS
CCCCCCCHHHHEECCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHCC
DKGLGRPREAYDRSVDVHISNIRQKLAALPGNHLNIETVRSIGYRIR
CCCCCCCHHHHCCCCEEEHHHHHHHHHHCCCCCCCHHHHHHCCCCCC
>Mature Secondary Structure
MKILLVDDDLELGTMLKEYLGGEGFTAKHVLTGKAGIDGALSGDYTALILDIMLPDMSGI
CEEEEECCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCCH
DVLRQVRKKSRLPIIMLTAKGDNIDRVIGLEMGADDYMPKPCYPRELVARLRAVLRRFEE
HHHHHHHHHCCCCEEEEEECCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHH
QPNLSATESSIITQGGLTLNPSTRSSEWQGKPFDLTASEFNLLELLLRSPERVVTKDELS
CCCCCCCHHHHEECCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHCC
DKGLGRPREAYDRSVDVHISNIRQKLAALPGNHLNIETVRSIGYRIR
CCCCCCCHHHHCCCCEEEHHHHHHHHHHCCCCCCCHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]