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The map label for this gene is astB

Identifier: 153947524

GI number: 153947524

Start: 2431891

End: 2433234

Strand: Reverse

Name: astB

Synonym: YpsIP31758_2118

Alternate gene names: 153947524

Gene position: 2433234-2431891 (Counterclockwise)

Preceding gene: 153947044

Following gene: 153950226

Centisome position: 51.52

GC content: 50.67

Gene sequence:

>1344_bases
ATGGCAGGATATGAAGTTAACTTCGATGGATTGGTTGGGCTAACGCATCATTATGCGGGGTTATCCTTTGGCAATGAGGC
ATCAACCACGCATCAAAACCATACTTCCAACCCTCGTTTGGCAGCCAAACAAGGGTTATTGAAGATGAAAGCCTTGGCGG
ATTTAGGCTACAAACAAGGGGTTCTCCCCCCTCAGGAGCGGCCGGCCATAGGCGTATTACGCAAGCTAGGGTTCAGTGGC
TCAGATGAACAGGTCTTAAGCGATGTTGCACGTAACGCGCCACGTTTACTCTCGGCGGTGAGTTCAGCATCCTCCATGTG
GACAGCCAATGCTGCAACGGTATCACCGTCAGCTGACAGTGCTGATGGGCGGGTCCATTTTACCGTTGCGAATTTGCATA
ATAAATTTCATCGGGCAATCGAGGCAGAGACAACCGCAGTATTGCTACCCGCGGTGTTCAATAACCACCGTCATTTTGTT
CATCATAATGCTTTACCTTCCGTGACCTTATTGGGAGATGAAGGGGCGGCGAACCATAACCGTCTGGGGGGCGAGTACGC
TAGCCCGGCAATCCAGATGTTTGTTTATGGCCGCCAAGGCATGGAGAGCGGGGCGGTTCCTGGCCGTTATCCTGCCAGAC
AAACACGTGAAGCCAGCCAGGCGGTGGCACGGTTGCATCAGTTGGACCCCAAACGCACCGTGTTTGTGCAACAAAACCCA
GCCGTGATCGATCAAGGCGTCTTTCACAACGATGTGATCGCAGTCAGTAACCGCAATGTATTATTCCATCATGAGTTGGC
TTTTCTATCGAGCACACAGGTCATGGACGATATTCGCTGCAAGATGGCAGGCTTGGAACAACAATTAGTCAATATTGAAG
TACCAGAAGCCGAAGTTTCCGTTGCTGATGCCGTGTCAACCTATCTGTTTAATAGCCAATTATTGCATAAGGCTAATGGC
AAAATGTTGTTGGTTATTCCGCAGGAGTCACAAGATAACCCCAGTGTATGGCGGTATTTATCTGAGTTGGTCAGCGGCGA
TGGGCCGATTGATGAACTCCGTGTTTTCGATCTGCGCGAGAGTATGCGTAATGGCGGTGGCCCGGCTTGCTTACGGTTGC
GGGTAGTCTTGAATGATGCTGAGCTACAGGCAGTTAACAGCCGAGTGATGCTGACACCGGCACTGTTTGTCACATTGAAT
AATTGGGTCGATCAACATTATCGGGACCACCTGCAGTTTAAAGATTTGGCAGATCCGCACTTGTTACAAGAAGGGCGGCA
AGCGTTGGATGAGTTAACGCGAATCCTCAATCTGGGGCCGGTGTACCCGTTCCAGCGCAATTAG

Upstream 100 bases:

>100_bases
CATCACTGGAGTGTGAGCACTTGATGTTACCCGTAACATTATCCCCCGGTATCTCTTTTGATTTGCCCAAGGCGTGATTG
AACCGTGTGTGGAGAAAATA

Downstream 100 bases:

>100_bases
CCGGTGTGGCTTTAGCGAATAACCGAACGGCTCAATGATAGAACCAATAGAGGAGCGATGATGCTGGATTTTTTAGCGAT
AACCCTATCGGGTAAACCTC

Product: succinylarginine dihydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 446

Protein sequence:

>447_residues
MAGYEVNFDGLVGLTHHYAGLSFGNEASTTHQNHTSNPRLAAKQGLLKMKALADLGYKQGVLPPQERPAIGVLRKLGFSG
SDEQVLSDVARNAPRLLSAVSSASSMWTANAATVSPSADSADGRVHFTVANLHNKFHRAIEAETTAVLLPAVFNNHRHFV
HHNALPSVTLLGDEGAANHNRLGGEYASPAIQMFVYGRQGMESGAVPGRYPARQTREASQAVARLHQLDPKRTVFVQQNP
AVIDQGVFHNDVIAVSNRNVLFHHELAFLSSTQVMDDIRCKMAGLEQQLVNIEVPEAEVSVADAVSTYLFNSQLLHKANG
KMLLVIPQESQDNPSVWRYLSELVSGDGPIDELRVFDLRESMRNGGGPACLRLRVVLNDAELQAVNSRVMLTPALFVTLN
NWVDQHYRDHLQFKDLADPHLLQEGRQALDELTRILNLGPVYPFQRN

Sequences:

>Translated_447_residues
MAGYEVNFDGLVGLTHHYAGLSFGNEASTTHQNHTSNPRLAAKQGLLKMKALADLGYKQGVLPPQERPAIGVLRKLGFSG
SDEQVLSDVARNAPRLLSAVSSASSMWTANAATVSPSADSADGRVHFTVANLHNKFHRAIEAETTAVLLPAVFNNHRHFV
HHNALPSVTLLGDEGAANHNRLGGEYASPAIQMFVYGRQGMESGAVPGRYPARQTREASQAVARLHQLDPKRTVFVQQNP
AVIDQGVFHNDVIAVSNRNVLFHHELAFLSSTQVMDDIRCKMAGLEQQLVNIEVPEAEVSVADAVSTYLFNSQLLHKANG
KMLLVIPQESQDNPSVWRYLSELVSGDGPIDELRVFDLRESMRNGGGPACLRLRVVLNDAELQAVNSRVMLTPALFVTLN
NWVDQHYRDHLQFKDLADPHLLQEGRQALDELTRILNLGPVYPFQRN
>Mature_446_residues
AGYEVNFDGLVGLTHHYAGLSFGNEASTTHQNHTSNPRLAAKQGLLKMKALADLGYKQGVLPPQERPAIGVLRKLGFSGS
DEQVLSDVARNAPRLLSAVSSASSMWTANAATVSPSADSADGRVHFTVANLHNKFHRAIEAETTAVLLPAVFNNHRHFVH
HNALPSVTLLGDEGAANHNRLGGEYASPAIQMFVYGRQGMESGAVPGRYPARQTREASQAVARLHQLDPKRTVFVQQNPA
VIDQGVFHNDVIAVSNRNVLFHHELAFLSSTQVMDDIRCKMAGLEQQLVNIEVPEAEVSVADAVSTYLFNSQLLHKANGK
MLLVIPQESQDNPSVWRYLSELVSGDGPIDELRVFDLRESMRNGGGPACLRLRVVLNDAELQAVNSRVMLTPALFVTLNN
WVDQHYRDHLQFKDLADPHLLQEGRQALDELTRILNLGPVYPFQRN

Specific function: Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2)

COG id: COG3724

COG function: function code E; Succinylarginine dihydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinylarginine dihydrolase family

Homologues:

Organism=Escherichia coli, GI1788041, Length=446, Percent_Identity=65.695067264574, Blast_Score=599, Evalue=1e-172,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ASTB_YERP3 (A7FIL3)

Other databases:

- EMBL:   CP000720
- RefSeq:   YP_001401091.1
- ProteinModelPortal:   A7FIL3
- SMR:   A7FIL3
- STRING:   A7FIL3
- GeneID:   5387917
- GenomeReviews:   CP000720_GR
- KEGG:   ypi:YpsIP31758_2118
- NMPDR:   fig|349747.3.peg.421
- eggNOG:   COG3724
- HOGENOM:   HBG289862
- OMA:   HFAHHPA
- ProtClustDB:   PRK13281
- BioCyc:   YPSE349747:YPSIP31758_2118-MONOMER
- HAMAP:   MF_01172
- InterPro:   IPR007079
- Gene3D:   G3DSA:3.75.10.20
- TIGRFAMs:   TIGR03241

Pfam domain/function: PF04996 AstB

EC number: =3.5.3.23

Molecular weight: Translated: 49170; Mature: 49039

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: NA

Important sites: ACT_SITE 174-174 ACT_SITE 249-249 ACT_SITE 370-370 BINDING 110-110 BINDING 213-213 BINDING 251-251 BINDING 364-364

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGYEVNFDGLVGLTHHYAGLSFGNEASTTHQNHTSNPRLAAKQGLLKMKALADLGYKQG
CCCCEECCCCCEEHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHCC
VLPPQERPAIGVLRKLGFSGSDEQVLSDVARNAPRLLSAVSSASSMWTANAATVSPSADS
CCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHEECCCEEECCCCCC
ADGRVHFTVANLHNKFHRAIEAETTAVLLPAVFNNHRHFVHHNALPSVTLLGDEGAANHN
CCCEEEEEEHHHHHHHHHHHHHCCCEEEEHHHHCCCCEEEECCCCCCEEEECCCCCCCCC
RLGGEYASPAIQMFVYGRQGMESGAVPGRYPARQTREASQAVARLHQLDPKRTVFVQQNP
CCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCC
AVIDQGVFHNDVIAVSNRNVLFHHELAFLSSTQVMDDIRCKMAGLEQQLVNIEVPEAEVS
CHHCCCCCCCCEEEEECCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHH
VADAVSTYLFNSQLLHKANGKMLLVIPQESQDNPSVWRYLSELVSGDGPIDELRVFDLRE
HHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHH
SMRNGGGPACLRLRVVLNDAELQAVNSRVMLTPALFVTLNNWVDQHYRDHLQFKDLADPH
HHHCCCCCEEEEEEEEECCHHHHHHCCEEEECHHHEEHHHHHHHHHHHHCCCHHCCCCHH
LLQEGRQALDELTRILNLGPVYPFQRN
HHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
AGYEVNFDGLVGLTHHYAGLSFGNEASTTHQNHTSNPRLAAKQGLLKMKALADLGYKQG
CCCEECCCCCEEHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHCC
VLPPQERPAIGVLRKLGFSGSDEQVLSDVARNAPRLLSAVSSASSMWTANAATVSPSADS
CCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHEECCCEEECCCCCC
ADGRVHFTVANLHNKFHRAIEAETTAVLLPAVFNNHRHFVHHNALPSVTLLGDEGAANHN
CCCEEEEEEHHHHHHHHHHHHHCCCEEEEHHHHCCCCEEEECCCCCCEEEECCCCCCCCC
RLGGEYASPAIQMFVYGRQGMESGAVPGRYPARQTREASQAVARLHQLDPKRTVFVQQNP
CCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCC
AVIDQGVFHNDVIAVSNRNVLFHHELAFLSSTQVMDDIRCKMAGLEQQLVNIEVPEAEVS
CHHCCCCCCCCEEEEECCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHH
VADAVSTYLFNSQLLHKANGKMLLVIPQESQDNPSVWRYLSELVSGDGPIDELRVFDLRE
HHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHH
SMRNGGGPACLRLRVVLNDAELQAVNSRVMLTPALFVTLNNWVDQHYRDHLQFKDLADPH
HHHCCCCCEEEEEEEEECCHHHHHHCCEEEECHHHEEHHHHHHHHHHHHCCCHHCCCCHH
LLQEGRQALDELTRILNLGPVYPFQRN
HHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA