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The map label for this gene is dacC [H]

Identifier: 153947077

GI number: 153947077

Start: 3011023

End: 3012225

Strand: Reverse

Name: dacC [H]

Synonym: YpsIP31758_2659

Alternate gene names: 153947077

Gene position: 3012225-3011023 (Counterclockwise)

Preceding gene: 153948441

Following gene: 153949300

Centisome position: 63.77

GC content: 47.88

Gene sequence:

>1203_bases
ATGATGAAATATATCCTCCCTTTCAAGATTAAAAATTTTACGTTCAGTGCAGGTTTATTGCTTCTGGCACTGCCTGCTTA
TGCAGTCGATGACCCTGCCGCTCCCCAGATTGATGCTAAAGCTTATGTGCTGATGGATTTTAATAGCGGAAAAGTGCTGG
CAGAAGGCAATCCTGATCTGCGCCTTGATCCGGCCAGTTTGACAAAAATCATGTCCAGCTATGTGATCGGGCAGTCGATT
AAAGCGGGCAAAATACAGCCTGATGATCTGGTCACCGTGGGGAAAGACGCCTGGGCGACCGGTAACCCAGCTCTGCGCGG
CTCGTCGCTGATGTTTTTGAAGCCGGGCGATCAGGTAAAAGTGTCTGATCTCAACAAAGGCATTGTGATCCAATCAGGTA
ATGATGCCAGTATTGCATTGGCTGATTATGTCGCGGGTAGTCAGGACAGTTTTGTTGGCCTGATGAATAACTACGCTAAA
GCACTTGGCCTGAGTAATACTCACTTTATGACGGTACACGGCCTGGATTCACCGGGGCAGTACAGTACTGCGCGTGATAT
GGCTTTACTGGGGCAGGCATTGATCCGCGATGTGCCAGAAGAATATGCGCTGCATAAAGAGAAAGAATTTACCTTTAATA
AAATCCGCCAAACCAACCGTAACCGGCTGTTATGGAACAGTAGTTTAAACGTTGATGGGATGAAAACCGGTTATACCAAC
GGGGCGGGGTATAATTTGGTCGCATCGGCGACAGATGGGCCGATGCGTTTGATTTCCGTGGTGCTGGGTGCACCAAGTGA
CAAAGTACGCTTTAGTGAAAGTGAAAAATTGCTGACTTGGGGTTTCCGCTTCTATGAAACCGTGGTGCCAATTAAATCAA
CAAAGCCATTTGTGACAGAGAAAGTGTGGCTTGGCGATAACAGCCAGGTTGAACTTGGGGTGGCGGAGGATGCAGCGATC
ACCATTCCTAAAGGGCAGATGAAAAATCTGAAAGCCAGTTATACCCTGAACCAAACCGAGCTACGCGCGCCGCTAGCGAA
ACATCAAGTGGTTGGAACCATCGATTTTCAACTCAATGGCAAAACCATTGAACAGCGCCCACTCGTGGTGTTGAATGAGG
TCAAAGAGGGGGGCATCTTTAGCCGTTTCTGGGATTACGTAATGATGAAACTTAACCAATGGTTTGGTGGGATATTCGGC
TAA

Upstream 100 bases:

>100_bases
AGTCTCAGTGGAAAGACGTTATTTTTCGCTAATTGGACAGTGGTGATCTCTGGGAATACCACTAATTTCCGATTATTTGC
AAGGATACTCTGGCGACCTC

Downstream 100 bases:

>100_bases
TTTAGCCAGTATTAGCCAGCAGAAACCCGTATTAGTCCGTAGAAATCAATAGACCGTAGAAACTAATAGACCGTAGAAAC
TAAGAGTCCTTAAAAACCCA

Product: D-alanyl-D-alanine carboxypeptidase

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase; Penicillin-binding protein 6; PBP-6 [H]

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MMKYILPFKIKNFTFSAGLLLLALPAYAVDDPAAPQIDAKAYVLMDFNSGKVLAEGNPDLRLDPASLTKIMSSYVIGQSI
KAGKIQPDDLVTVGKDAWATGNPALRGSSLMFLKPGDQVKVSDLNKGIVIQSGNDASIALADYVAGSQDSFVGLMNNYAK
ALGLSNTHFMTVHGLDSPGQYSTARDMALLGQALIRDVPEEYALHKEKEFTFNKIRQTNRNRLLWNSSLNVDGMKTGYTN
GAGYNLVASATDGPMRLISVVLGAPSDKVRFSESEKLLTWGFRFYETVVPIKSTKPFVTEKVWLGDNSQVELGVAEDAAI
TIPKGQMKNLKASYTLNQTELRAPLAKHQVVGTIDFQLNGKTIEQRPLVVLNEVKEGGIFSRFWDYVMMKLNQWFGGIFG

Sequences:

>Translated_400_residues
MMKYILPFKIKNFTFSAGLLLLALPAYAVDDPAAPQIDAKAYVLMDFNSGKVLAEGNPDLRLDPASLTKIMSSYVIGQSI
KAGKIQPDDLVTVGKDAWATGNPALRGSSLMFLKPGDQVKVSDLNKGIVIQSGNDASIALADYVAGSQDSFVGLMNNYAK
ALGLSNTHFMTVHGLDSPGQYSTARDMALLGQALIRDVPEEYALHKEKEFTFNKIRQTNRNRLLWNSSLNVDGMKTGYTN
GAGYNLVASATDGPMRLISVVLGAPSDKVRFSESEKLLTWGFRFYETVVPIKSTKPFVTEKVWLGDNSQVELGVAEDAAI
TIPKGQMKNLKASYTLNQTELRAPLAKHQVVGTIDFQLNGKTIEQRPLVVLNEVKEGGIFSRFWDYVMMKLNQWFGGIFG
>Mature_400_residues
MMKYILPFKIKNFTFSAGLLLLALPAYAVDDPAAPQIDAKAYVLMDFNSGKVLAEGNPDLRLDPASLTKIMSSYVIGQSI
KAGKIQPDDLVTVGKDAWATGNPALRGSSLMFLKPGDQVKVSDLNKGIVIQSGNDASIALADYVAGSQDSFVGLMNNYAK
ALGLSNTHFMTVHGLDSPGQYSTARDMALLGQALIRDVPEEYALHKEKEFTFNKIRQTNRNRLLWNSSLNVDGMKTGYTN
GAGYNLVASATDGPMRLISVVLGAPSDKVRFSESEKLLTWGFRFYETVVPIKSTKPFVTEKVWLGDNSQVELGVAEDAAI
TIPKGQMKNLKASYTLNQTELRAPLAKHQVVGTIDFQLNGKTIEQRPLVVLNEVKEGGIFSRFWDYVMMKLNQWFGGIFG

Specific function: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors [H]

COG id: COG1686

COG function: function code M; D-alanyl-D-alanine carboxypeptidase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein. Note=N-terminal lies in the periplasmic space [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S11 family [H]

Homologues:

Organism=Escherichia coli, GI1787062, Length=385, Percent_Identity=73.5064935064935, Blast_Score=596, Evalue=1e-172,
Organism=Escherichia coli, GI1786851, Length=394, Percent_Identity=63.9593908629442, Blast_Score=526, Evalue=1e-151,
Organism=Escherichia coli, GI87082022, Length=378, Percent_Identity=48.9417989417989, Blast_Score=385, Evalue=1e-108,
Organism=Escherichia coli, GI87082054, Length=251, Percent_Identity=27.4900398406374, Blast_Score=84, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015956
- InterPro:   IPR018044
- InterPro:   IPR012907
- InterPro:   IPR001967 [H]

Pfam domain/function: PF07943 PBP5_C; PF00768 Peptidase_S11 [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 43849; Mature: 43849

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKYILPFKIKNFTFSAGLLLLALPAYAVDDPAAPQIDAKAYVLMDFNSGKVLAEGNPDL
CCCEEEEEEECCEEEHHCHHHHHCCCCCCCCCCCCCCCCEEEEEEEECCCEEEECCCCCC
RLDPASLTKIMSSYVIGQSIKAGKIQPDDLVTVGKDAWATGNPALRGSSLMFLKPGDQVK
EECHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCEEEEECCCCEEE
VSDLNKGIVIQSGNDASIALADYVAGSQDSFVGLMNNYAKALGLSNTHFMTVHGLDSPGQ
EEECCCCEEEECCCCCEEEEEEHHCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCC
YSTARDMALLGQALIRDVPEEYALHKEKEFTFNKIRQTNRNRLLWNSSLNVDGMKTGYTN
CCHHHHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHCCCCEEEEECCCCCCCCCCCCCC
GAGYNLVASATDGPMRLISVVLGAPSDKVRFSESEKLLTWGFRFYETVVPIKSTKPFVTE
CCCCEEEEECCCCHHHHHHHHHCCCCCCEEECCCCCEEEEHHHHHHEEECCCCCCCCEEE
KVWLGDNSQVELGVAEDAAITIPKGQMKNLKASYTLNQTELRAPLAKHQVVGTIDFQLNG
EEEECCCCEEEEEECCCCEEEECCCHHHCCEEEEEECHHHHHCCHHHCEEEEEEEEEECC
KTIEQRPLVVLNEVKEGGIFSRFWDYVMMKLNQWFGGIFG
CEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MMKYILPFKIKNFTFSAGLLLLALPAYAVDDPAAPQIDAKAYVLMDFNSGKVLAEGNPDL
CCCEEEEEEECCEEEHHCHHHHHCCCCCCCCCCCCCCCCEEEEEEEECCCEEEECCCCCC
RLDPASLTKIMSSYVIGQSIKAGKIQPDDLVTVGKDAWATGNPALRGSSLMFLKPGDQVK
EECHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCEEEEECCCCEEE
VSDLNKGIVIQSGNDASIALADYVAGSQDSFVGLMNNYAKALGLSNTHFMTVHGLDSPGQ
EEECCCCEEEECCCCCEEEEEEHHCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCC
YSTARDMALLGQALIRDVPEEYALHKEKEFTFNKIRQTNRNRLLWNSSLNVDGMKTGYTN
CCHHHHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHCCCCEEEEECCCCCCCCCCCCCC
GAGYNLVASATDGPMRLISVVLGAPSDKVRFSESEKLLTWGFRFYETVVPIKSTKPFVTE
CCCCEEEEECCCCHHHHHHHHHCCCCCCEEECCCCCEEEEHHHHHHEEECCCCCCCCEEE
KVWLGDNSQVELGVAEDAAITIPKGQMKNLKASYTLNQTELRAPLAKHQVVGTIDFQLNG
EEEECCCCEEEEEECCCCEEEECCCHHHCCEEEEEECHHHHHCCHHHCEEEEEEEEEECC
KTIEQRPLVVLNEVKEGGIFSRFWDYVMMKLNQWFGGIFG
CEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3279397; 8905232; 9278503; 7042389 [H]