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The map label for this gene is plsB [H]

Identifier: 153946857

GI number: 153946857

Start: 4249907

End: 4252384

Strand: Direct

Name: plsB [H]

Synonym: YpsIP31758_3772

Alternate gene names: 153946857

Gene position: 4249907-4252384 (Clockwise)

Preceding gene: 153947273

Following gene: 153949827

Centisome position: 89.98

GC content: 49.96

Gene sequence:

>2478_bases
ATGTCAGGTTGGCGTAAAATATATTATAAGTTACTGAATTTACCACTCAAATTGTTGGTAAAAAGCAAGGTTATCCCTGC
AGATCCGGTCTCTGAGCTAGGGCTAGACCCTTCTCGTCCTATTCTGTACGTTTTACCTTACAATTCTAAGGCTGATTTGC
TGACGTTACGGGCACAGTGCTTGGCGCAAGATCTGCCCGATCCATTGATTCCATTGGAAATCGATGGCGTGCAATTGCCC
AGCCATGTGTTTATCGAGAACGGGCCAAGAGTCTTTCGCTACTATGTTCCTAAACAAGAATCGGTGAAGCTATTCCACGA
TTATCTGGATTTACATCGTAATAATCCGGCGCTAGATATTCAGATGTTACCCGTTTCCGTGATGTTTGGCCGTTCCCCTG
GGCGCGAAGGCCACGGTACGCCACATCTGCGGGTACTTAACGGTGTACAGAAATTCTTTGCTGTATTGTGGTTGGGGCGC
GACAGTTTTGTGCGTTTTTCTACCACCGTATCGCTACGCCGAATGGCCAGTGAGCACGGTACCGATAAAACTATCGCCCA
TAAACTGGCACGTGTGGCGCGGATGCACTTCTCTCGTCAACGTTTGGCCGCGGTAGGTCCGAGTTTACCTGCCCGTCAGG
ATCTGTTTAAAAAACTCTTGGCCTCTAAGGCTATCGAGAAAGCTGTCGCTGACGAGGCGCGGTCGAAAAAAATCTCCCAT
GAAAAAGCACAGCAAAACGCCATCACTCTGATGGAAGAGATTGCGGCTAATTTCTCCTATGAAGCCGTGCGGTTGTCTGA
TCGGGTACTTAGCTGGACGTGGAACCGTTTGTATCAGGGGATTAACGTTCATAATGCAGAGCGGGTCCGGCAATTGGCAC
AAGATGGCCATGAGATCGTCTATGTACCTTGTCATCGCAGCCATATGGATTACCTGCTGCTCTCCTATGTGCTCTACCAT
CAGGGGCTGGTCCCACCGCATATCGCCGCAGGGATTAACCTCAACTTCTGGCCTGCCGGGCCAATCTTCCGCCGTTTAGG
CGCATTCTTTATCCGCCGTACCTTTAAAGGCAATAAACTCTACTCAACGGTGTTCCGCGAATATCTGGGTGAGCTATTTA
CTCGTGGCTATTCCGTTGAATACTTTGTTGAAGGGGGGCGTTCGCGGACTGGCCGCCTGTTGGAGCCGAAAACCGGCACC
TTGTCGATGACGATTCAGGCCATGTTACGTGGTGGCACCCGCCCTATCACGTTGGTGCCGATTTACATCGGCTACGAGCA
TGTTATGGAAGTGGGGACTTACGCCAAAGAGTTGCGCGGTGCGATAAAAGAAAAAGAGAACCTGTTACAGATGCTACGTG
GCTTACGTAAGTTGCGTAATCTCGGCCAGGGCTATGTGAACTTTGGCGAACCCCTGCCATTGACGACCTACCTTAATACC
CATGTGCCACAGTGGCGGGATGCCATCGATCCCATTGAAGCACAGCGCCCAAGTTGGCTAACACCGGCAGTGAATGATTT
GGCTAATCAGATTATGGTCCGAATCAACAATGCGGCAGCAGCAAATGCCATGAATCTCTGTTCAACGGCGTTACTCGCCT
CACGTCAGCGTTCACTAACCCGTGAGCAGCTACTTGAGCAACTTGATTGCTATCTGCAATTAATGCGCAATGCACCCTAT
GCAAAAGATACTACCGTGCCGGATAAAACACCGGAAGAGTTGCTTAATCACGCCTTGAATATGAATAAGTTTGAGGTGGA
GAAAGACACCATCGGTGACATCATCATCCTGCCACGGGAACAGGCCGTGCTGATGACCTATTATCGCAATAATATTCAGC
ACTTACTGATATTGCCATCGCTGATTGCCAGTATGGTCATGTACCACCGCCGGATTACCCGGACGGAGTTACTGCACAAA
ATCAGCATGATCTATCCAATGCTAAAAGCTGAACTGTTCCTGCATTACAGCAAAGAGCAGCTACCAGAGACTCTGGATAC
ATTGATCGATGAGCTGGCTCGTCAGCAGTTAATTTGTGATAAAGGCAGCGAATTGGTCCTGAATCCGGCACGCATTCGCC
CACTGCAATTGCTGGCCGCAGGTGTGCGGGAAACGCTACAACGCTACGCGATCACACTTTCACTCCTCAGCGCTACCCCC
AGTATCAACCGTGGGGCATTGGAGAAAGAGAGCCGCATTATGGCGCAGCGCTTGTCGGTTCTGCATGGTATTAATGCGCC
GGAATTCTTTGATAAAGCGGTCTTCTCAACGCTGGTTGCGACCTTGCGTGAAGAAGGCTATATCAGTGATAGCGGTGATG
CCATTCAGGAACATACGCTGGAAGTTTACAATATGCTGAGTGCGTTGATGACCCCAGAAGTAAAGCTGACTATCGAAAGT
GTCAGTATGCCAGCGGAGACCAGCAATCAGCCAGAAGCTCCAGAGACACCAGAGCCTGAGGGTAAAACGGAATCCTAA

Upstream 100 bases:

>100_bases
TCGTGATTTTTGCCATTTTCTGTTGTCTCATCTCCACAGATCTCAAAACCAGTTTCTGGTATCCTTGCGACGAATTGCTA
ACAAGAGGCTCCAAGTCGTT

Downstream 100 bases:

>100_bases
TGTCTTAGCGTACTCAATGCTTAACAGCCCCCTGCCTAGCAGGGGGTTTTCTGAATACCATAACAATGGCCGGACTCATT
ATCCGGCCATTTTTTACCAT

Product: glycerol-3-phosphate acyltransferase

Products: NA

Alternate protein names: GPAT [H]

Number of amino acids: Translated: 825; Mature: 824

Protein sequence:

>825_residues
MSGWRKIYYKLLNLPLKLLVKSKVIPADPVSELGLDPSRPILYVLPYNSKADLLTLRAQCLAQDLPDPLIPLEIDGVQLP
SHVFIENGPRVFRYYVPKQESVKLFHDYLDLHRNNPALDIQMLPVSVMFGRSPGREGHGTPHLRVLNGVQKFFAVLWLGR
DSFVRFSTTVSLRRMASEHGTDKTIAHKLARVARMHFSRQRLAAVGPSLPARQDLFKKLLASKAIEKAVADEARSKKISH
EKAQQNAITLMEEIAANFSYEAVRLSDRVLSWTWNRLYQGINVHNAERVRQLAQDGHEIVYVPCHRSHMDYLLLSYVLYH
QGLVPPHIAAGINLNFWPAGPIFRRLGAFFIRRTFKGNKLYSTVFREYLGELFTRGYSVEYFVEGGRSRTGRLLEPKTGT
LSMTIQAMLRGGTRPITLVPIYIGYEHVMEVGTYAKELRGAIKEKENLLQMLRGLRKLRNLGQGYVNFGEPLPLTTYLNT
HVPQWRDAIDPIEAQRPSWLTPAVNDLANQIMVRINNAAAANAMNLCSTALLASRQRSLTREQLLEQLDCYLQLMRNAPY
AKDTTVPDKTPEELLNHALNMNKFEVEKDTIGDIIILPREQAVLMTYYRNNIQHLLILPSLIASMVMYHRRITRTELLHK
ISMIYPMLKAELFLHYSKEQLPETLDTLIDELARQQLICDKGSELVLNPARIRPLQLLAAGVRETLQRYAITLSLLSATP
SINRGALEKESRIMAQRLSVLHGINAPEFFDKAVFSTLVATLREEGYISDSGDAIQEHTLEVYNMLSALMTPEVKLTIES
VSMPAETSNQPEAPETPEPEGKTES

Sequences:

>Translated_825_residues
MSGWRKIYYKLLNLPLKLLVKSKVIPADPVSELGLDPSRPILYVLPYNSKADLLTLRAQCLAQDLPDPLIPLEIDGVQLP
SHVFIENGPRVFRYYVPKQESVKLFHDYLDLHRNNPALDIQMLPVSVMFGRSPGREGHGTPHLRVLNGVQKFFAVLWLGR
DSFVRFSTTVSLRRMASEHGTDKTIAHKLARVARMHFSRQRLAAVGPSLPARQDLFKKLLASKAIEKAVADEARSKKISH
EKAQQNAITLMEEIAANFSYEAVRLSDRVLSWTWNRLYQGINVHNAERVRQLAQDGHEIVYVPCHRSHMDYLLLSYVLYH
QGLVPPHIAAGINLNFWPAGPIFRRLGAFFIRRTFKGNKLYSTVFREYLGELFTRGYSVEYFVEGGRSRTGRLLEPKTGT
LSMTIQAMLRGGTRPITLVPIYIGYEHVMEVGTYAKELRGAIKEKENLLQMLRGLRKLRNLGQGYVNFGEPLPLTTYLNT
HVPQWRDAIDPIEAQRPSWLTPAVNDLANQIMVRINNAAAANAMNLCSTALLASRQRSLTREQLLEQLDCYLQLMRNAPY
AKDTTVPDKTPEELLNHALNMNKFEVEKDTIGDIIILPREQAVLMTYYRNNIQHLLILPSLIASMVMYHRRITRTELLHK
ISMIYPMLKAELFLHYSKEQLPETLDTLIDELARQQLICDKGSELVLNPARIRPLQLLAAGVRETLQRYAITLSLLSATP
SINRGALEKESRIMAQRLSVLHGINAPEFFDKAVFSTLVATLREEGYISDSGDAIQEHTLEVYNMLSALMTPEVKLTIES
VSMPAETSNQPEAPETPEPEGKTES
>Mature_824_residues
SGWRKIYYKLLNLPLKLLVKSKVIPADPVSELGLDPSRPILYVLPYNSKADLLTLRAQCLAQDLPDPLIPLEIDGVQLPS
HVFIENGPRVFRYYVPKQESVKLFHDYLDLHRNNPALDIQMLPVSVMFGRSPGREGHGTPHLRVLNGVQKFFAVLWLGRD
SFVRFSTTVSLRRMASEHGTDKTIAHKLARVARMHFSRQRLAAVGPSLPARQDLFKKLLASKAIEKAVADEARSKKISHE
KAQQNAITLMEEIAANFSYEAVRLSDRVLSWTWNRLYQGINVHNAERVRQLAQDGHEIVYVPCHRSHMDYLLLSYVLYHQ
GLVPPHIAAGINLNFWPAGPIFRRLGAFFIRRTFKGNKLYSTVFREYLGELFTRGYSVEYFVEGGRSRTGRLLEPKTGTL
SMTIQAMLRGGTRPITLVPIYIGYEHVMEVGTYAKELRGAIKEKENLLQMLRGLRKLRNLGQGYVNFGEPLPLTTYLNTH
VPQWRDAIDPIEAQRPSWLTPAVNDLANQIMVRINNAAAANAMNLCSTALLASRQRSLTREQLLEQLDCYLQLMRNAPYA
KDTTVPDKTPEELLNHALNMNKFEVEKDTIGDIIILPREQAVLMTYYRNNIQHLLILPSLIASMVMYHRRITRTELLHKI
SMIYPMLKAELFLHYSKEQLPETLDTLIDELARQQLICDKGSELVLNPARIRPLQLLAAGVRETLQRYAITLSLLSATPS
INRGALEKESRIMAQRLSVLHGINAPEFFDKAVFSTLVATLREEGYISDSGDAIQEHTLEVYNMLSALMTPEVKLTIESV
SMPAETSNQPEAPETPEPEGKTES

Specific function: De novo phospholipid biosynthesis; first step. [C]

COG id: COG2937

COG function: function code I; Glycerol-3-phosphate O-acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPAT/DAPAT family [H]

Homologues:

Organism=Homo sapiens, GI7657134, Length=442, Percent_Identity=28.5067873303167, Blast_Score=154, Evalue=4e-37,
Organism=Homo sapiens, GI190358539, Length=466, Percent_Identity=24.4635193133047, Blast_Score=132, Evalue=1e-30,
Organism=Escherichia coli, GI87082362, Length=803, Percent_Identity=80.1992528019925, Blast_Score=1323, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71988723, Length=276, Percent_Identity=32.9710144927536, Blast_Score=150, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI25147672, Length=295, Percent_Identity=30.5084745762712, Blast_Score=144, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI71988728, Length=192, Percent_Identity=38.0208333333333, Blast_Score=136, Evalue=4e-32,
Organism=Drosophila melanogaster, GI17864692, Length=340, Percent_Identity=27.9411764705882, Blast_Score=145, Evalue=1e-34,
Organism=Drosophila melanogaster, GI24650754, Length=406, Percent_Identity=26.8472906403941, Blast_Score=135, Evalue=1e-31,
Organism=Drosophila melanogaster, GI21357731, Length=405, Percent_Identity=26.9135802469136, Blast_Score=135, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24650752, Length=502, Percent_Identity=25.0996015936255, Blast_Score=135, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR022284 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.15 [H]

Molecular weight: Translated: 93623; Mature: 93492

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGWRKIYYKLLNLPLKLLVKSKVIPADPVSELGLDPSRPILYVLPYNSKADLLTLRAQC
CCHHHHHHHHHHHCHHHHHHHCCCCCCCCHHHCCCCCCCCEEEEECCCCCCHHHHHHHHH
LAQDLPDPLIPLEIDGVQLPSHVFIENGPRVFRYYVPKQESVKLFHDYLDLHRNNPALDI
HHHHCCCCCCEEEECCEECCCEEEECCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCEEE
QMLPVSVMFGRSPGREGHGTPHLRVLNGVQKFFAVLWLGRDSFVRFSTTVSLRRMASEHG
EEECEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHCC
TDKTIAHKLARVARMHFSRQRLAAVGPSLPARQDLFKKLLASKAIEKAVADEARSKKISH
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKAQQNAITLMEEIAANFSYEAVRLSDRVLSWTWNRLYQGINVHNAERVRQLAQDGHEIV
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCEEE
YVPCHRSHMDYLLLSYVLYHQGLVPPHIAAGINLNFWPAGPIFRRLGAFFIRRTFKGNKL
EECCCCCHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHH
YSTVFREYLGELFTRGYSVEYFVEGGRSRTGRLLEPKTGTLSMTIQAMLRGGTRPITLVP
HHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEECCCCCCHHHHHHHHHCCCCCCEEEEE
IYIGYEHVMEVGTYAKELRGAIKEKENLLQMLRGLRKLRNLGQGYVNFGEPLPLTTYLNT
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEHHHCC
HVPQWRDAIDPIEAQRPSWLTPAVNDLANQIMVRINNAAAANAMNLCSTALLASRQRSLT
CCCCHHHHCCCHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
REQLLEQLDCYLQLMRNAPYAKDTTVPDKTPEELLNHALNMNKFEVEKDTIGDIIILPRE
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCEEECCCCCCCEEEECCC
QAVLMTYYRNNIQHLLILPSLIASMVMYHRRITRTELLHKISMIYPMLKAELFLHYSKEQ
CHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
LPETLDTLIDELARQQLICDKGSELVLNPARIRPLQLLAAGVRETLQRYAITLSLLSATP
HHHHHHHHHHHHHHHHHHHCCCCCEEECHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
SINRGALEKESRIMAQRLSVLHGINAPEFFDKAVFSTLVATLREEGYISDSGDAIQEHTL
CCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
EVYNMLSALMTPEVKLTIESVSMPAETSNQPEAPETPEPEGKTES
HHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SGWRKIYYKLLNLPLKLLVKSKVIPADPVSELGLDPSRPILYVLPYNSKADLLTLRAQC
CHHHHHHHHHHHCHHHHHHHCCCCCCCCHHHCCCCCCCCEEEEECCCCCCHHHHHHHHH
LAQDLPDPLIPLEIDGVQLPSHVFIENGPRVFRYYVPKQESVKLFHDYLDLHRNNPALDI
HHHHCCCCCCEEEECCEECCCEEEECCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCEEE
QMLPVSVMFGRSPGREGHGTPHLRVLNGVQKFFAVLWLGRDSFVRFSTTVSLRRMASEHG
EEECEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHCC
TDKTIAHKLARVARMHFSRQRLAAVGPSLPARQDLFKKLLASKAIEKAVADEARSKKISH
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKAQQNAITLMEEIAANFSYEAVRLSDRVLSWTWNRLYQGINVHNAERVRQLAQDGHEIV
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCEEE
YVPCHRSHMDYLLLSYVLYHQGLVPPHIAAGINLNFWPAGPIFRRLGAFFIRRTFKGNKL
EECCCCCHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHH
YSTVFREYLGELFTRGYSVEYFVEGGRSRTGRLLEPKTGTLSMTIQAMLRGGTRPITLVP
HHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEECCCCCCHHHHHHHHHCCCCCCEEEEE
IYIGYEHVMEVGTYAKELRGAIKEKENLLQMLRGLRKLRNLGQGYVNFGEPLPLTTYLNT
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEHHHCC
HVPQWRDAIDPIEAQRPSWLTPAVNDLANQIMVRINNAAAANAMNLCSTALLASRQRSLT
CCCCHHHHCCCHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
REQLLEQLDCYLQLMRNAPYAKDTTVPDKTPEELLNHALNMNKFEVEKDTIGDIIILPRE
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCEEECCCCCCCEEEECCC
QAVLMTYYRNNIQHLLILPSLIASMVMYHRRITRTELLHKISMIYPMLKAELFLHYSKEQ
CHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
LPETLDTLIDELARQQLICDKGSELVLNPARIRPLQLLAAGVRETLQRYAITLSLLSATP
HHHHHHHHHHHHHHHHHHHCCCCCEEECHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
SINRGALEKESRIMAQRLSVLHGINAPEFFDKAVFSTLVATLREEGYISDSGDAIQEHTL
CCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
EVYNMLSALMTPEVKLTIESVSMPAETSNQPEAPETPEPEGKTES
HHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA