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The map label for this gene is xpt-1

Identifier: 153937838

GI number: 153937838

Start: 364554

End: 365126

Strand: Direct

Name: xpt-1

Synonym: CLC_0375

Alternate gene names: 153937838

Gene position: 364554-365126 (Clockwise)

Preceding gene: 153934932

Following gene: 153936909

Centisome position: 9.69

GC content: 30.54

Gene sequence:

>573_bases
GTGGAAAAATTACAAAATCGTATTTTACAAGAAGGTCATGCATTATCTGAAACTGTATTAAAGGTGGATTCTTTTTTAAA
TCATCAAGTAGATCCAGATTTAATGTATGAAATAGGAACTTATTTTAAAAATTATTTTAAAGAACATAAAATCACAAAGG
TATTTACAATTGAAAGTTCAGGAATTGCTCCAGCTGTTATGACTGCAATGCAAATGAATTTGCCAATGGTAATATTAAAA
AAACAAGCATCAAAAATTTTAAATGGAGATGTTTATCAAACCACTGTACATTCATTTACAAAGGGATTGGATTATGAACT
AACATTATCTAAAAAATATATTGCCAAAGAGGACAATATATTAATTATAGATGATTTTCTAGCAAATGGAGAAGCAGCAT
TAGGAGCTGCACGTTTAGTTAAAGAGGCAGGGGCTAAAGTTGCTGGAATGGGGATTGTTATTGAGAAGTCATTCCAACCG
GGAAGAAAGATGTTAGAAGACAAAGGATATGATGTGTATTCACTAGCACGTATAGCAAAACTTCAAAAAGGCTTAATTGA
ATTTGTAAAGTAA

Upstream 100 bases:

>100_bases
ATGATTTTTTCATCAGGAATTTCAACTGGAACAATTGTAGCTTTATTATTAAATGTAATATTAAAAGAAAAAGAATAAGG
AATTTTACGGGGTGATATAA

Downstream 100 bases:

>100_bases
AAGTATTTTAATTATTGAATTCTAAAATAGTACTTATTGGTAATTATGTAAGACTATATTTCAAAATAGATTTAATTTTA
ATATGGCAAAGATAAAAAAC

Product: xanthine phosphoribosyltransferase

Products: NA

Alternate protein names: XPRTase 1

Number of amino acids: Translated: 190; Mature: 190

Protein sequence:

>190_residues
MEKLQNRILQEGHALSETVLKVDSFLNHQVDPDLMYEIGTYFKNYFKEHKITKVFTIESSGIAPAVMTAMQMNLPMVILK
KQASKILNGDVYQTTVHSFTKGLDYELTLSKKYIAKEDNILIIDDFLANGEAALGAARLVKEAGAKVAGMGIVIEKSFQP
GRKMLEDKGYDVYSLARIAKLQKGLIEFVK

Sequences:

>Translated_190_residues
MEKLQNRILQEGHALSETVLKVDSFLNHQVDPDLMYEIGTYFKNYFKEHKITKVFTIESSGIAPAVMTAMQMNLPMVILK
KQASKILNGDVYQTTVHSFTKGLDYELTLSKKYIAKEDNILIIDDFLANGEAALGAARLVKEAGAKVAGMGIVIEKSFQP
GRKMLEDKGYDVYSLARIAKLQKGLIEFVK
>Mature_190_residues
MEKLQNRILQEGHALSETVLKVDSFLNHQVDPDLMYEIGTYFKNYFKEHKITKVFTIESSGIAPAVMTAMQMNLPMVILK
KQASKILNGDVYQTTVHSFTKGLDYELTLSKKYIAKEDNILIIDDFLANGEAALGAARLVKEAGAKVAGMGIVIEKSFQP
GRKMLEDKGYDVYSLARIAKLQKGLIEFVK

Specific function: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XPT subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XPT1_CLOB1 (A7FPI7)

Other databases:

- EMBL:   CP000726
- RefSeq:   YP_001382719.1
- ProteinModelPortal:   A7FPI7
- SMR:   A7FPI7
- STRING:   A7FPI7
- GeneID:   5397542
- GenomeReviews:   CP000726_GR
- KEGG:   cba:CLB_0360
- eggNOG:   COG0503
- HOGENOM:   HBG288993
- OMA:   ATVYSFT
- ProtClustDB:   PRK09219
- BioCyc:   CBOT441770:CLB_0360-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01184
- InterPro:   IPR000836
- InterPro:   IPR010079
- TIGRFAMs:   TIGR01744

Pfam domain/function: PF00156 Pribosyltran

EC number: =2.4.2.22

Molecular weight: Translated: 21279; Mature: 21279

Theoretical pI: Translated: 9.14; Mature: 9.14

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: BINDING 20-20 BINDING 27-27 BINDING 156-156

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKLQNRILQEGHALSETVLKVDSFLNHQVDPDLMYEIGTYFKNYFKEHKITKVFTIESS
CHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECC
GIAPAVMTAMQMNLPMVILKKQASKILNGDVYQTTVHSFTKGLDYELTLSKKYIAKEDNI
CCHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEECHHHHCCCCCE
LIIDDFLANGEAALGAARLVKEAGAKVAGMGIVIEKSFQPGRKMLEDKGYDVYSLARIAK
EEEECCCCCCCHHHHHHHHHHHHCCCEECCEEEEECCCCCHHHHHHHCCCCHHHHHHHHH
LQKGLIEFVK
HHHHHHHHCC
>Mature Secondary Structure
MEKLQNRILQEGHALSETVLKVDSFLNHQVDPDLMYEIGTYFKNYFKEHKITKVFTIESS
CHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECC
GIAPAVMTAMQMNLPMVILKKQASKILNGDVYQTTVHSFTKGLDYELTLSKKYIAKEDNI
CCHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEECHHHHCCCCCE
LIIDDFLANGEAALGAARLVKEAGAKVAGMGIVIEKSFQPGRKMLEDKGYDVYSLARIAK
EEEECCCCCCCHHHHHHHHHHHHCCCEECCEEEEECCCCCHHHHHHHCCCCHHHHHHHHH
LQKGLIEFVK
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA