Click here to switch to the map view.

The map label for this gene is treR [H]

Identifier: 153937812

GI number: 153937812

Start: 2055684

End: 2056394

Strand: Direct

Name: treR [H]

Synonym: CLC_1935

Alternate gene names: 153937812

Gene position: 2055684-2056394 (Clockwise)

Preceding gene: 153936849

Following gene: 153937199

Centisome position: 54.66

GC content: 25.6

Gene sequence:

>711_bases
ATGGAAAGCAAATATTTGACTATTTATAATGAGATTTCAAATAAAATAGAAAATAATAAAATTCAATCCGGCGAAAAACT
TTCTTCTGAAAATGAAATGATGAAAGAATATAATGTATCTAGAGATACCATAAGAAAAGCATTAAATTTGCTGGAAAGTA
ATGGTTATATTCAAAAAGTGAAAGGTAAAGGTTCCTTTGTACTAGATATTAATAAATTTGATTTTCCTGTTTCAGGACTT
ACAAGTTTTAAAGAATTATCTACTAGAATGGGAGTAGAATCTAATACCCTAGTTAAAGAATTAAAGTTAATAAAGCCAGA
TAACTTTTTAATGAAACAACTAAACCTATCAAAAAACGATGACGTGTGGAAAGTTATAAGAGTAAGAGAAATAGATAATA
AAAAAATTATCTTAGATAAAGACTTTTTTAATAAGAAATATGTTCCTTTATTAACTAAAGATATTTGTGAAAATTCTATA
TATGAATATCTTGAAAATGAACTAGGACTTAAAATTAGCTTTGCTAAAAAGGAAATTACAGTGCAGCAAGCTACACAGGA
AGACAAATCATATTTAGATTTTGAAAATTATAATATGATAGTGGTGGTAAAAAACTATATATATCTAGATGATATGAGTC
TATTTCAGTACACTGAATCTAGACATAGACCGGATAGATTTAAATTTGTAGAATTTGCAAGAAGAAAATAG

Upstream 100 bases:

>100_bases
CTATAGACTTTAGAAAAATTAATTTAAGACCTTATGAGTCTATAGTTTACCATCTTGAGAGAAAATAAAAAAAATGTTAA
AATGTTTCTGGTGATAAGAT

Downstream 100 bases:

>100_bases
TAATGCTTTTGATTTTATACTAATAGTTCAGAAAAGAAATTGCTTCATTAAGATAGGTTTATATTTGCGCCTTTAAAATA
AAATTAAATCATTTTATTTT

Product: trehalose operon repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MESKYLTIYNEISNKIENNKIQSGEKLSSENEMMKEYNVSRDTIRKALNLLESNGYIQKVKGKGSFVLDINKFDFPVSGL
TSFKELSTRMGVESNTLVKELKLIKPDNFLMKQLNLSKNDDVWKVIRVREIDNKKIILDKDFFNKKYVPLLTKDICENSI
YEYLENELGLKISFAKKEITVQQATQEDKSYLDFENYNMIVVVKNYIYLDDMSLFQYTESRHRPDRFKFVEFARRK

Sequences:

>Translated_236_residues
MESKYLTIYNEISNKIENNKIQSGEKLSSENEMMKEYNVSRDTIRKALNLLESNGYIQKVKGKGSFVLDINKFDFPVSGL
TSFKELSTRMGVESNTLVKELKLIKPDNFLMKQLNLSKNDDVWKVIRVREIDNKKIILDKDFFNKKYVPLLTKDICENSI
YEYLENELGLKISFAKKEITVQQATQEDKSYLDFENYNMIVVVKNYIYLDDMSLFQYTESRHRPDRFKFVEFARRK
>Mature_236_residues
MESKYLTIYNEISNKIENNKIQSGEKLSSENEMMKEYNVSRDTIRKALNLLESNGYIQKVKGKGSFVLDINKFDFPVSGL
TSFKELSTRMGVESNTLVKELKLIKPDNFLMKQLNLSKNDDVWKVIRVREIDNKKIILDKDFFNKKYVPLLTKDICENSI
YEYLENELGLKISFAKKEITVQQATQEDKSYLDFENYNMIVVVKNYIYLDDMSLFQYTESRHRPDRFKFVEFARRK

Specific function: Repressor for the trehalose operon (treP and treA). Binds trehalose-6-phosphate, which probably acts as an inducer [H]

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786950, Length=232, Percent_Identity=28.8793103448276, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1790540, Length=234, Percent_Identity=23.5042735042735, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI87082252, Length=192, Percent_Identity=26.5625, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1790118, Length=149, Percent_Identity=30.2013422818792, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1788418, Length=226, Percent_Identity=19.9115044247788, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000524
- InterPro:   IPR012770
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 27934; Mature: 27934

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESKYLTIYNEISNKIENNKIQSGEKLSSENEMMKEYNVSRDTIRKALNLLESNGYIQKV
CCCCEEEHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEE
KGKGSFVLDINKFDFPVSGLTSFKELSTRMGVESNTLVKELKLIKPDNFLMKQLNLSKND
CCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHCCCCCCC
DVWKVIRVREIDNKKIILDKDFFNKKYVPLLTKDICENSIYEYLENELGLKISFAKKEIT
CCEEEEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEECHHHHH
VQQATQEDKSYLDFENYNMIVVVKNYIYLDDMSLFQYTESRHRPDRFKFVEFARRK
HHHHHHHHHCCCCCCCCCEEEEEEEEEEECCHHHHHHHHHCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MESKYLTIYNEISNKIENNKIQSGEKLSSENEMMKEYNVSRDTIRKALNLLESNGYIQKV
CCCCEEEHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEE
KGKGSFVLDINKFDFPVSGLTSFKELSTRMGVESNTLVKELKLIKPDNFLMKQLNLSKND
CCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHCCCCCCC
DVWKVIRVREIDNKKIILDKDFFNKKYVPLLTKDICENSIYEYLENELGLKISFAKKEIT
CCEEEEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEECHHHHH
VQQATQEDKSYLDFENYNMIVVVKNYIYLDDMSLFQYTESRHRPDRFKFVEFARRK
HHHHHHHHHCCCCCCCCCEEEEEEEEEEECCHHHHHHHHHCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8917076; 8969503; 9384377; 7651129; 8755887 [H]